Abstract:
PURPOSE:The natural history and optimal management strategy for men with human immunodeficiency virus (HIV) and prostate cancer remain to be definitively characterized. This study was conducted to evaluate the clinical characteristics and outcomes of HIV-seropositive men treated with robotic-assisted radical laparoscopic prostatectomy for localized prostate cancer. METHODS:After Institutional Review Board approval, a prospective database of 2175 operative cases of clinically localized prostate adenocarcinoma was reviewed. Thirteen patients were identified as HIV-positive. Tumor characteristics, operative outcomes, postoperative outcomes, histology (Gleason score), local invasion, biochemical recurrence, and surgical complications were compared with HIV-negative patients. RESULTS:There were no preoperative demographic differences between the HIV-positive and HIV-negative patients. HIV-positive patients had higher prostate specific antigen (PSA) levels at time of diagnosis which was not statistically significant. However, HIV-positive patients had higher D'Amico risk assessment (p < 0.05). There was no postoperative complication. HIV-positive patients treated with robotic prostatectomy had similarly favorable perioperative and short-term biochemical recurrence-free survival outcomes. CONCLUSION:Our findings show that minimally invasive prostatectomy can be safely considered as a therapeutic option in otherwise eligible HIV-positive patients with clinically significant prostate cancer. Further research is necessary to outline a diagnostic and treatment guideline for HIV-positive men in detection and treatment of prostate cancer.
journal_name
Int Urol Nephroljournal_title
International urology and nephrologyauthors
Izadmehr S,Leapman M,Hobbs AR,Katsigeorgis M,Nabizada-Pace F,Jazayeri SB,Samadi DBdoi
10.1007/s11255-016-1338-4subject
Has Abstractpub_date
2016-10-01 00:00:00pages
1639-45issue
10eissn
0301-1623issn
1573-2584pii
10.1007/s11255-016-1338-4journal_volume
48pub_type
杂志文章abstract::Infertility in a large proportion of infertile couples is due, in part, to the male factor. Spermatozoa must survive the unique environment of the female reproductive tract in their path to fertilize the ovum. This fact is even more problematic for men with oligospermia. Of the many environmental factors that effect s...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-008-9493-x
更新日期:2009-01-01 00:00:00
abstract::We report on our experience with a new surgical procedure of forming a pseudoneotesticle from indigenous tissues obtained from the existing scrotal contents. This procedure has been performed in 32 patients with a diagnosis of hormone dependent cancer of the prostate as a therapeutic manoeuvre, and in 3 children who h...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02550317
更新日期:1998-01-01 00:00:00
abstract::Primary CNS lymphoma (PCNSL) is a rare B cell variant non-Hodgkins lymphoma that is confined to the brain, leptomeninges, spinal cord and eyes. Its incidence is increasing, primarily due to increase in the number of organ transplantations being undertaken. The majority of the PTLD (post-transplant lymphoproliferative ...
journal_title:International urology and nephrology
pub_type: 杂志文章,评审
doi:10.1007/s11255-012-0146-8
更新日期:2013-08-01 00:00:00
abstract::The best "treatment" of acute kidney injury (AKI) is prevention. Patients who are at high risk of AKI should have an assessment of their volume status and receive appropriate volume expansion. The most effective type of intravenous fluid remains unclear. Innumerable studies have compared sodium bicarbonate and isotoni...
journal_title:International urology and nephrology
pub_type: 社论,评审
doi:10.1007/s11255-014-0820-0
更新日期:2015-02-01 00:00:00
abstract::A case of spontaneous right uretero-cutaneous fistula complicated by spontaneous rupture of the urinary bladder is presented. This morbid state is extremely rare and has not been previously reported to the best of our knowledge. ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02564762
更新日期:1995-01-01 00:00:00
abstract:PURPOSE:To share our 7-year experiences of a safe and effective method for tract creation in percutaneous nephrolithotomy (PCNL). METHODS:A total of 143 patients had received this kind of method for renal stone disease at our institute from May 2010 to December 2016. Finally, 130 patients with complete data were inclu...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-018-1949-z
更新日期:2018-09-01 00:00:00
abstract:PURPOSE:Physical inactivity and sleep disturbance are frequently observed and relate to poor clinical outcomes in maintenance hemodialysis patients. We aimed to investigate the effect of intradialytic exercise on daily physical activity and sleep quality, measured by an accelerometer, in maintenance hemodialysis patien...
journal_title:International urology and nephrology
pub_type: 杂志文章,随机对照试验
doi:10.1007/s11255-018-1796-y
更新日期:2018-04-01 00:00:00
abstract::We aimed to investigate whether high peripheral and cavernosal plasma levels of apolipoprotein-(a) [Lp (a)] is an indicator for vasculogenic erectile dysfunction. We determined Lp (a), total cholesterol (TC), triglyceride (TG) and high density lipoprotein (HDL) levels in peripheral and cavernosal blood in 39 patients ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02550575
更新日期:1998-01-01 00:00:00
abstract::Hemangiopericytoma (HPC) arising from within the urinary bladder is exceptionally rare. A 45-year-old man having the symptoms of left groin pain, vague suprapubic discomfort and frequency was admitted to our clinic. Pelvic tomography revealed a tumor in the bladder wall measuring 4 x 3 cm and was not clearly distinct ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-006-6673-4
更新日期:2006-01-01 00:00:00
abstract:AIM:To evaluate the infectious complications, microorganism distribution and antibacterial treatment in patients who underwent percutaneous nephrolithotomy (PCNL). PATIENTS AND METHODS:Three hundred and thirty-eight patients who were 17 years age or older who underwent PCNL between January 2001 and December 2002 have ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-006-9147-9
更新日期:2007-01-01 00:00:00
abstract:PURPOSE:Uremic toxins produced by gut microbiota (indoxyl sulfate-IS, p-cresyl sulfate-p-CS, and indole-3-acetic acid-IAA) accumulate in hemodialysis (HD) patients and exhibit potent inflammatory effects. However, the impact of these toxins on nuclear E2-related factor 2 (Nrf2) and nuclear factor-kappa B (NF-κB) expres...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-017-1748-y
更新日期:2018-02-01 00:00:00
abstract:OBJECTIVE:Evaluation of ultrasonographic abnormalities with active Schistosoma haematobium infection in Yemeni patients. METHODS:As part of a cooperation between a private hospital and Schistosomiasis Control Project in Yemen, laboratory and ultrasonographic examinations were performed in 158 patients (8 females, 150 ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1023/a:1007168507070
更新日期:1999-01-01 00:00:00
abstract::A total of 42 neurologically normal children with different voiding problems have been studied urodynamically during the last 4 years. Seventeen patients had unstable bladder, with significantly decreased capacity. The degree of volume decrease depended on the severity of instability and on the type of micturition pro...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:
更新日期:1993-01-01 00:00:00
abstract::Fifty-eight patients with urate calculi and 31 patients with other (non-urate) calculi were examined for total-body potassium by means of a total-body counter. The patients with urate calculosis were found to differ significantly in their total-body K from patients with other calculi as well as from normal subjects. T...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02082228
更新日期:1979-01-01 00:00:00
abstract:OBJECTIVE:To analyze the effect of age on nutrition indices in subjects on the same continuous ambulatory peritoneal dialysis (CAPD) schedule. METHODS:We analyzed 613 sets of clearance values and nutrition indices in 302 CAPD patients. Small solute clearances included urea clearance (Kt/Vurea) and creatinine clearance...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1023/a:1017579105158
更新日期:2001-01-01 00:00:00
abstract::Biomedical informatics in Health (BIH) is the discipline in charge of capturing, handling and using information in health and biomedicine in order to improve the processes involved with assistance and management. Informatic nephrology has appeared as a product of the combination between conventional nephrology with BI...
journal_title:International urology and nephrology
pub_type: 杂志文章,评审
doi:10.1007/s11255-012-0282-1
更新日期:2013-08-01 00:00:00
abstract:PURPOSE:The age-related decline of the testosterone-to-estrogen (T-to-E2) ratio in serum is associated with the increased prevalence of prostatic inflammation. The goal of the study was to induce prostatic inflammation with E2 and androgen treatment and to explore the inflammatory markers and apoptosis on prostatitis. ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-014-0845-4
更新日期:2015-01-01 00:00:00
abstract:PURPOSE:In this research, the normal anatomy of urethral sphincter complex in young Chinese males has been studied. METHODS:The sagittal, coronal, and axial T2-weighted non-fat suppressed fast spin-echo images of pelvic cavities of 86 Chinese young males were studied. RESULT:Urethral sphincter complex is a cylindrica...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-014-0686-1
更新日期:2014-08-01 00:00:00
abstract:OBJECTIVE:Some studies have found that prostate cancer (PCa) screening provides little or no change in PCa-related mortality during the 7-10 years following diagnoses. However, most men are diagnosed with PCa at low-stage disease and die of unrelated causes during this period. Men diagnosed at stage IV are at much high...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-010-9799-3
更新日期:2011-06-01 00:00:00
abstract:AIM:The complete biological effects of chronic use of dehydroepiandrosterone (DHEA), reported as a weak androgen, are not completely understood. The aim of the present study is to evaluate the effects of chronic administration of DHEA on the spermatogenesis in rats. METHODS:Male Wistar rats, 4 months old, were selecte...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1023/a:1025918228851
更新日期:2003-01-01 00:00:00
abstract::The incidence of cytomegalovirus infection in Chinese patients was reviewed in a retrospective study of 99 renal transplant recipients. CMV infection occurred in 18 patients (18.2%). In 4 the infection was considered primary and in 14 it was thought to be reactivation. Of the infections 88.9% occurred within the first...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02767664
更新日期:1994-01-01 00:00:00
abstract:PURPOSE:Chronic kidney disease is independently associated with an increased risk of cardiovascular events; however, the relationship between the glomerular filtration rate (GFR) and coronary artery disease (CAD) in patients undergoing coronary angiography has yet to be fully elucidated. METHODS:This retrospective stu...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-011-0070-3
更新日期:2012-08-01 00:00:00
abstract:PURPOSE:In large observational studies of adult kidney transplant recipients (KTRs) where older adults (65 years old and older) were not well represented, the mammalian target of rapamycin inhibitors (mTOR inhibitors) has poorer outcomes than the standard tacrolimus-mycophenolate-steroids (TAC-MPA-S) regimen. We conduc...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-019-02251-w
更新日期:2019-11-01 00:00:00
abstract:BACKGROUND:According to the concept of integrated care, renal transplantation, peritoneal dialysis (PD), and hemodialysis (HD) should be considered three complementary methods of renal replacement therapy. This study tried to evaluate patient outcomes in three different groups of PD patients, namely primary PD patients...
journal_title:International urology and nephrology
pub_type: 杂志文章,多中心研究
doi:10.1007/s11255-011-0068-x
更新日期:2012-08-01 00:00:00
abstract:OBJECTIVE:Fatigue and depressed mood are considered main impediments to physical activity in haemodialysis (HD) patients. A better understanding of their interrelationships is crucial to develop effective therapies. Moreover, measurement of daily physical activity (DPA) in HD patients is tricky, as it is usually assess...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-020-02578-9
更新日期:2020-10-01 00:00:00
abstract:PURPOSE:To investigate the effects of combined treatment of tadalafil (a phosphodiesterase-5 inhibitor) and tamsulosin (an α1-adrenoceptor antagonist) on bladder dysfunction in a rat model of bladder outlet obstruction (BOO). METHODS:Cystometry was performed in conscious female BOO rats 6 weeks after partially ligatio...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-018-1835-8
更新日期:2018-05-01 00:00:00
abstract::Fibrosing cholestatic hepatitis (FCH) is an uncommon complication of renal transplantation. It is usually associated with hepatitis B and C viral infection. It is further rare in renal transplantation in absence of HBV and HCV infection. To the best of our knowledge, only three cases of FCH in renal transplantation, w...
journal_title:International urology and nephrology
pub_type: 杂志文章,评审
doi:10.1007/s11255-004-6196-9
更新日期:2004-01-01 00:00:00
abstract::A male with a severe form of congenital nephrogenic diabetes insipidus (diuresis 10 l per day) had megaureters, megavesica, large residuum and a history of three traumatic ruptures of the megavesica and a recurrent urinary tract infection (RUTI). Hemodialysis was introduced at 41 years of age. At age of 42, he underwe...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-006-0093-3
更新日期:2006-01-01 00:00:00
abstract::In recent years, the role of trace elements in lithogenesis has received steadily increasing attention. It is well documented that some trace elements can influence the morphology and speed of the crystallization process. Zinc has been found in significant amounts in calcium stones relative or organic stones (uric aci...
journal_title:International urology and nephrology
pub_type: 杂志文章,评审
doi:10.1007/s11255-017-1784-7
更新日期:2018-05-01 00:00:00
abstract::The aim of this report is to emphasize the use of methylene staining test and the Nd:YAG laser in the diagnosis and treatment of premalignant lesions and CIS of the bladder. The use of an appropriate solution of methylene blue (0.2% in 0.9 M NaCl for 15 min) permits the staining of premalignant areas and CIS, and thei...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02559739
更新日期:1989-01-01 00:00:00