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Patient outcome in primary peritoneal dialysis patients versus those transferred from hemodialysis and transplantation.

Abstract：

BACKGROUND:According to the concept of integrated care, renal transplantation, peritoneal dialysis (PD), and hemodialysis (HD) should be considered three complementary methods of renal replacement therapy. This study tried to evaluate patient outcomes in three different groups of PD patients, namely primary PD patients, those transferred to PD with failing kidney transplant, and those transferred to PD from HD. METHOD:From January 1, 1995, to end of 2006 from 26 PD centers, 1,355 patients including demographic, clinical and laboratory data, which were monthly collected through questionnaires, were enrolled in the study. We compared patients' characteristics, factors affecting patient survival, and patient outcomes between primary PD patients (group 1, n = 1,067), patients transferred from transplantation (group 2, n = 43) and those transferred from HD (group 3, n = 245), which had been on HD for at least 3 months before switching to PD. RESULTS:There was no difference in the proportion of patients with diabetes in the three groups. Overall, 238 patients (17.5%) were transferred to HD but there was no significant difference in PD technique survival on between the three groups. Death occurred in 256 (24%), 3 (7%) and 65 (26.5%) subjects in groups 1, 2 and 3, respectively. Most patients (81.5%) in group 2 underwent re-transplantation. The Kaplan-Meier survival rates were not different between the three groups. In the Cox multiple regression model, age, presence of diabetes and serum albumin level significantly influenced patient survival. CONCLUSION:We concluded that PD could be considered safe for patients experiencing complications on HD, as well as for those with renal transplantation.

journal_name

Int Urol Nephrol

journal_title

International urology and nephrology

authors

Najafi I,Hosseini M,Atabac S,Sanadgol H,Majelan NN,Seirafian S,Naghibi M,Makhdoumi K,Saddadi F,Soleymanian T

doi

10.1007/s11255-011-0068-x

subject

Has Abstract

pub_date

2012-08-01 00:00:00

pages

1237-42

issue

eissn

0301-1623

issn

1573-2584

journal_volume

pub_type

杂志文章,多中心研究

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Patient outcome in primary peritoneal dialysis patients versus those transferred from hemodialysis and transplantation.