Abstract:
PURPOSE:TNF-α -308G/A polymorphism has been implicated in the susceptibility of diabetic nephropathy, but studies have reported inconclusive results. The present study investigated the relationship between -308G/A polymorphism in the TNF-α gene and diabetic nephropathy risk by meta-analysis. METHODS:Data from PubMed, Embase, Ovid, Cochrane Library, China National Knowledge Infrastructure, Wanfang, VIP and China Biology Medicine disc databases were evaluated and analyzed. Statistical analysis was performed using RevMan 4.2 and Stata 10.0 software. RESULTS:A total of 1,277 diabetic nephropathy cases and 1,740 controls in eight case-controlled studies were identified for data analysis. The results suggested that A allele carriers (GA + AA) may not have an altered risk of diabetic nephropathy when compared with homozygote GG carriers with boarder-line statistical significance (OR = 0.84, 95 % CI = 0.71-1.00, p = 0.05 for GA + AA vs. GG). However, in Asian subgroup analysis, the A allele variant was associated with a decreased diabetic nephropathy risk (OR = 0.69, 95 % CI = 0.51-0.94, p = 0.02 for GA + AA vs. GG) CONCLUSIONS:Meta-analysis suggests that the A allele of TNF-α -308G/A polymorphism might be protective against diabetic nephropathy with ethnic selectivity. Future studies are needed to validate these findings.
journal_name
Int Urol Nephroljournal_title
International urology and nephrologyauthors
Zhao Y,Yang J,Zhang L,Li Z,Yang Y,Tang Y,Fu Pdoi
10.1007/s11255-013-0490-3subject
Has Abstractpub_date
2013-12-01 00:00:00pages
1653-9issue
6eissn
0301-1623issn
1573-2584journal_volume
45pub_type
杂志文章,meta分析abstract::We report a case of 20-year-old farmer with penile amputation and emasculation secondary to crushing injury inflicted by agricultural machinery. His entire penis, scrotum and both the testis had been avulsed after falling onto a rotating axel wheel of an electronically driven thrashing machine. After resuscitation the...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-004-0918-x
更新日期:2004-01-01 00:00:00
abstract:PURPOSE:The venous thromboembolic events (VTE) incidence is high in nephrotic syndrome (NS). We aimed to assess prospectively the risk of VTE in a large cohort of NS patients and to identify predictive factors for VTE, especially haemostasis-related parameters. METHODS:This is the prospective, observational study cond...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-013-0574-0
更新日期:2014-04-01 00:00:00
abstract:AIM:The aim of this study is to assess whether the haemostatic markers D-dimer, factor VIII (FVIII) and von Willebrand factor (VWF) are predictive of non-dipping status in treated hypertensive patients; so, as easy available laboratory data can predict non-dipping pattern and help with the selection of the patients who...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-012-0288-8
更新日期:2013-06-01 00:00:00
abstract::Two cases of rarely observed granulomatous prostatitis are presented. Unspecific clinical symptoms and a close similarity in clinical course to prostatic adenoma or adenocarcinoma may be misleading and produce severe diagnostic difficulties even for an experienced urologist. Close cooperation with a pathomorphologist ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02084115
更新日期:1986-01-01 00:00:00
abstract::Hemangiopericytoma (HPC) arising from within the urinary bladder is exceptionally rare. A 45-year-old man having the symptoms of left groin pain, vague suprapubic discomfort and frequency was admitted to our clinic. Pelvic tomography revealed a tumor in the bladder wall measuring 4 x 3 cm and was not clearly distinct ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-006-6673-4
更新日期:2006-01-01 00:00:00
abstract:PURPOSE:Varicocele is among the leading causes of male infertility. Despite decades of research, its pathogenesis is still unclear. S100A12 is a member of the S100 family of calcium-binding proteins with principal extracellular activities. It is secreted by activated neutrophils and interacts with the multiligand recep...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-015-1188-5
更新日期:2016-03-01 00:00:00
abstract:BACKGROUND:Significantly increased cardiovascular mortality in patients with chronic kidney (CKD) disease cannot be explained by traditional risk factors. Recent studies revealed that the quality of HDL and LDL cholesterol may be more important than their serum levels. The aim of this study was to assess which LDL and ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-016-1466-x
更新日期:2017-01-01 00:00:00
abstract::Hydatid disease of the urinary tract is very rare. We report a case of pure renal hydatid cyst, with its clinical presentation and management. ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02551409
更新日期:1997-01-01 00:00:00
abstract::The follow-up study has been performed in 4 male patients with nephrogenic diabetes insipidus lasting for 4 to 15 years. Hydronephrosis or hydroureter appeared to be caused by polyuria with or without urinary tract obstruction. The efficacy of drainage operation is emphasized when polyuria surpasses the transporting a...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02549772
更新日期:1990-01-01 00:00:00
abstract:PURPOSE:Smoking habit is the major risk factor for bladder cancer (BC), related to about 50% of these tumors; however, the tobacco dose-effect impact on BC immune treatment is underexplored. This study evaluates the impact of smoke load on non-muscle invasive bladder cancer (NMIBC) prognosis after intravesical BCG. ME...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-020-02438-6
更新日期:2020-08-01 00:00:00
abstract:OBJECTIVE:To analyze indications, surgical technique, complications and long-term outcomes of kidney autotransplantation (KAT) after 26-year experience at a single institution. MATERIALS AND METHODS:A retrospective observational study of patients who underwent KAT at our institution (January 1990-December 2016) was ca...
journal_title:International urology and nephrology
pub_type: 杂志文章,评审
doi:10.1007/s11255-017-1680-1
更新日期:2017-11-01 00:00:00
abstract::We report 3 cases of benign retroperitoneal schwannoma, of whom one presented with flank pain with hematuria, one presented with headache and secondary hypertension and one presented with recurrent renal colicky pain. Two patients were treated by open surgical excision of the tumor with nephrectomy of the correspondin...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-004-4705-5
更新日期:2005-01-01 00:00:00
abstract::Investigating the reliability of using some clinical and laboratory parameters as long-term prognostic factors in properly selected patients for stress urinary surgery could help in the prediction of the long-term result in each case. Toward this goal 51 women were examined prospectively, after they were assessed by c...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02575219
更新日期:1995-01-01 00:00:00
abstract::In developing countries, renal transplantation is offered to young end-stage renal disease (ESRD) patients, while the older ones face limitations due to higher mortality risk. We retrospectively analyzed 225 patients who underwent renal transplantation from living donors, aged 40-60 years (Group A) and >60 years (Grou...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-010-9887-4
更新日期:2011-03-01 00:00:00
abstract::Chronic renal failure is a risk factor for tuberculosis. In the past five years we have identified two cases of tuberculosis in our dialysis population. The first patient, showed chronic failure to thrive on hemodialysis. An enlarged cervical lymph node was biopsied and, although no acid fast bacilli (AFB) were seen, ...
journal_title:International urology and nephrology
pub_type: 杂志文章,评审
doi:10.1023/a:1007108809773
更新日期:2000-01-01 00:00:00
abstract::Kidney injury molecule-1 (KIM-1) staining has been shown to be very useful in identifying acute proximal tubular injury, but its sensitivity, specificity and predicting values for the recovery of renal function after injury in renal biopsies have not been well established. In the first study, we randomly selected 184 ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-019-02311-1
更新日期:2019-12-01 00:00:00
abstract:OBJECTIVE:The growth of solid tumors requires angiogenesis. Evidence indicates that mast cells (MCs) play an important role in tumor angiogenesis but results are not definitive. The aim of this study is to investigate the possible effects of angiogenesis and the presence of MCs on the prognosis of renal cell carcinoma ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-009-9577-2
更新日期:2010-03-01 00:00:00
abstract:OBJECTIVE:Evaluation of ultrasonographic abnormalities with active Schistosoma haematobium infection in Yemeni patients. METHODS:As part of a cooperation between a private hospital and Schistosomiasis Control Project in Yemen, laboratory and ultrasonographic examinations were performed in 158 patients (8 females, 150 ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1023/a:1007168507070
更新日期:1999-01-01 00:00:00
abstract::Penile cancer is an uncommon disease in the industrialized world that most frequently presents at low stage and is cured with treatment of local and regional surgery. In cases of advanced cancer, the use of more aggressive surgical techniques and the addition of adjuvant therapy may be warranted. So far, few agents ha...
journal_title:International urology and nephrology
pub_type: 杂志文章,评审
doi:10.1007/s11255-011-0011-1
更新日期:2012-02-01 00:00:00
abstract:PURPOSE:In this research, the normal anatomy of urethral sphincter complex in young Chinese males has been studied. METHODS:The sagittal, coronal, and axial T2-weighted non-fat suppressed fast spin-echo images of pelvic cavities of 86 Chinese young males were studied. RESULT:Urethral sphincter complex is a cylindrica...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-014-0686-1
更新日期:2014-08-01 00:00:00
abstract:PURPOSE:We have recently reported lipopolysaccharide (LPS) pretreatment attenuated renal ischemia/reperfusion injury (IRI), but the exact mechanism remains to be well elucidated. It was reported that heat shock protein (Hsp) 27 was up-regulated after administration of LPS, but whether a direct link existed between Hsp2...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-017-1735-3
更新日期:2018-03-01 00:00:00
abstract:PURPOSE:Cognitive dysfunction (CO/DY) in chronic kidney disease (CKD) patients has long been recognized. Hypertension is also associated with CO/DY. The study describes associated factors with CO/DY in CKD patients compared to hypertensive subjects. METHODS:Ninety-six hypertensive subjects without CKD, 19 patients wit...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-013-0450-y
更新日期:2013-12-01 00:00:00
abstract::Deoxyribonuclease (DNase) activity and metal ion concentrations in lymphocytes of patients with chronic renal failure and in healthy controls were studied. The data suggest that T and B lymphocyte nuclei of patients with renal failure show increased DNase activity when compared to their healthy counterparts. It is sug...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02552124
更新日期:1992-01-01 00:00:00
abstract:OBJECTIVE:To evaluate the relationship between the expression of E-cadherin (E-CD) and tumor recurrence and progression in patients with high-grade stage T1 urothelial carcinoma of bladder. METHODS:Fifty-two patients who had primary high-grade stage T1 urothelial carcinoma were enrolled to the study. The pathologic sp...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-006-9159-5
更新日期:2007-01-01 00:00:00
abstract:INTRODUCTION:To find the most beneficial method, we assessed patient comfort and morbidity rates during prostate biopsy procedures performed using periprostatic nerve blockade, unilateral pudendal nerve blockade, intrarectal lidocaine gel, and a combination of periprostatic nerve blockade and intrarectal lidocaine gel....
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-007-9237-3
更新日期:2008-01-01 00:00:00
abstract::The results of treatment by means of modified RLND in 52 patients with clinical stage I non-seminomatous testicular cancer are presented. Retroperitoneal lymph node metastases were found in 15 patients (28.8%) with clinical stage I (CS-I) diagnosed prior to surgery. They received chemotherapy according to PVB schedule...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02768020
更新日期:1994-01-01 00:00:00
abstract::Methylene blue (MB) alone, MB metabolites in the urine and the effect of MB plus alkalization on Candida species were determined. MB was used for the treatment of childhood renal candidiasis (CRC) in 3 patients as an irrigating solution. Besides irrigation, fluconazole 3 mg/kg/day intravenously and MB 0.2 mg/kg/day we...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02550565
更新日期:1998-01-01 00:00:00
abstract::The treatment of hyponatremia, especially euvolemic and hypervolemic hyponatremia, has changed with the development of drugs which function as vasopressin receptor antagonists. These agents increase solute-free water excretion by the kidney resulting in an aquaresis. Conivaptan, a vasopressin receptor antagonist, has ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-008-9353-8
更新日期:2008-01-01 00:00:00
abstract:OBJECTIVE:Previous studies on the association between extracorporeal shock wave lithotripsy (SWL) and new onset hypertension have only illustrated contradictory results. In order to illustrate the association between SWL and new onset hypertension, a meta-analysis of case-control and cohort studies was conducted. METH...
journal_title:International urology and nephrology
pub_type: 杂志文章,meta分析,评审
doi:10.1007/s11255-013-0588-7
更新日期:2014-04-01 00:00:00
abstract:OBJECTIVE/BACKGROUND:The aim of this study was to evaluate the efficacy of the autologous fascia rectus sling in treating stress urinary incontinence in female patients with neuropathic bladder. Furthermore, correlations between preoperative parameters and outcome were evaluated. METHODS AND DESIGN:We retrospectively ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-012-0247-4
更新日期:2012-10-01 00:00:00