Abstract:
:In recent years, the role of trace elements in lithogenesis has received steadily increasing attention. It is well documented that some trace elements can influence the morphology and speed of the crystallization process. Zinc has been found in significant amounts in calcium stones relative or organic stones (uric acid and cystine), probably substituting calcium in crystals because of their similarity in charge and size. High Zn levels are present in carbapatite of Randal's plaques suggesting that zinc could promote calcium phosphate deposition in the medullar interstitium. Large-scale epidemiological studies have found an association of increased dietary zinc intake with increased risk of nephrolithiasis in adults but not in adolescents. Most studies examining urinary zinc levels in adults have reported increased urinary Zn excretion in stone formers. In an experimental model of organic crystal formation produced by silencing xanthine dehydrogenase in Drosophila fly, maneuvers that reduce Zn excretion have shown to reduce crystal formation in the lumen of the Malpighian tubules. This is curious because this is not a model of calcium stone formation. Finally, zinc supplementation has been associated with increased admissions for urinary lithiasis in men, but no change in calcium stone formation in children. Perhaps, some of these contradicting findings can be explained in part by the in vitro effect of zinc on the type and amount of calcium phosphate formed: At low concentrations, Zn inhibited the crystal growth of dicalcium phosphate dihydrate, octacalcium phosphate, and apatite, and at higher concentrations, it promoted the formation of amorphous calcium phosphate. Thus, further studies are needed to see whether manipulation of Zn metabolism can inhibit calcium stone formation.
journal_name
Int Urol Nephroljournal_title
International urology and nephrologyauthors
Negri ALdoi
10.1007/s11255-017-1784-7subject
Has Abstractpub_date
2018-05-01 00:00:00pages
879-883issue
5eissn
0301-1623issn
1573-2584pii
10.1007/s11255-017-1784-7journal_volume
50pub_type
杂志文章,评审abstract:BACKGROUND AND AIM:Fungal peritonitis is a rare but serious complication in patients undergoing peritoneal dialysis (PD). We aimed to analyze the predisposing factors, clinical aspects, etiological agents, and treatment of fungal peritonitis in patients with PD in our hospital. PATIENTS AND METHODS:The data of all pat...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-010-9763-2
更新日期:2011-03-01 00:00:00
abstract::During a 3-year period, hundreds of patients underwent ESWL treatment with the Dornier HM-3 and HM-4 lithotriptors operating at our institution. Our experience in 3,500 patients treated with the HM-4 bath-free lithotriptor is reported. Patients with radiolucent or cystine stones, stones larger than 3 cm or staghorn ca...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02551334
更新日期:1997-01-01 00:00:00
abstract::Platinum (Pt) concentrations in the kidney and liver were determined in 12 autopsied cases following cisplatin treatment. The Pt level in the liver was generally higher than that in the kidney. Pt concentration in the liver showed a significant correlation with the total dose of cisplatin. However, no dose-dependent P...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:
更新日期:1993-01-01 00:00:00
abstract:PURPOSE:The current study was conducted to determine the effects of coenzyme Q10 (CoQ10) supplementation on glycemic control and markers of lipid profiles risk in diabetic hemodialysis (HD) patients. METHODS:This randomized, double blind, placebo-controlled clinical trial was performed among 60 diabetic HD patients. S...
journal_title:International urology and nephrology
pub_type: 杂志文章,随机对照试验
doi:10.1007/s11255-018-1973-z
更新日期:2018-11-01 00:00:00
abstract::Accurate knowledge about the morphology and degree of infiltration of a bladder tumor is an essential prerequisite to correctly plan, and forecast the results of, the treatment of these tumors. Among the radiological investigations double contrast cystography is superior to excretory cystogram or conventional cystogra...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02082014
更新日期:1977-01-01 00:00:00
abstract::Serum concentrations of carboxyterminal propeptide of type I procollagen (PICP) and carboxyterminal parathyroid hormone (C-PTH) were measured in 33 haemodialysis patients. Serum levels of PICP and C-PTH in the haemodialysis group were significantly higher than those in the controls. Although there was no correlation b...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02550286
更新日期:1998-01-01 00:00:00
abstract::Peyronie's disease is characterized by the formation of a fibrotic plaque in the tunica albugenia of the penis. Two patients with calcified butterfly shaped plaques involving the ventrolateral aspect of the penis are described. These patients were managed by plaque excision and dermal grafting with excellent post-oper...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1023/a:1021371315460
更新日期:2002-01-01 00:00:00
abstract::Most of the purported links between microbial agents and primary small-vessel anti-neutrophilic antibody-positive (ANCA) vasculitides remain speculative. There is strong circumstantial evidence for the role of Staphylococcus aureus in the development of Wegener's granulomatosis, but its role in other ANCA-positive vas...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-009-9652-8
更新日期:2010-09-01 00:00:00
abstract::Primary sclerosing lipogranuloma is an unusual benign condition of the genitalia typically presenting as a painless mass affecting the penis and scrotum. Its importance lies in differentiating it from malignancy to avoid extensive surgery. It is normally treated with total or partial excision. This is the first report...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-005-8572-5
更新日期:2006-01-01 00:00:00
abstract:BACKGROUND:Contrast-induced nephropathy (CIN) is an adverse consequence of contrast media use that results in significant morbidity and mortality and adds significant costs to diagnostic and interventional cardiology procedures. Various pathophysiological mechanisms have been proposed for CIN and various agents have be...
journal_title:International urology and nephrology
pub_type: 杂志文章,随机对照试验
doi:10.1007/s11255-011-0053-4
更新日期:2012-08-01 00:00:00
abstract::A 40-year-old man was referred to our hospital with gynecomastia and painless swelling of the right scrotum. Ultrasonography revealed a 15 x 10 mm mass with low echogenicity of the right testis. We performed right high orchiectomy. Histologically, Reinke's crystals and capsular invasion by tumor cells were found. Fina...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-006-6661-8
更新日期:2006-01-01 00:00:00
abstract::Silicon transfers were examined during haemodialysis (HD) in 120 chronic HD patients who received 5-hour dialyses 3 times a week. Si levels were measured by flameless atomic absorption spectrophotometry. Ultrafiltrable Si levels approximately equalled dialysate Si levels. Serum Si levels before HD significantly increa...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02549799
更新日期:1990-01-01 00:00:00
abstract:BACKGROUND:Undescended testis is a common problem, which is prevalent in 3 % of male infants. This study aimed to determine the effect of leaving the deep inguinal ring (DIR) without closure during laparoscopic orchiopexy (LO), with regard to post-operative hernia formation and other outcomes. METHODS:From 2012 to 201...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-016-1438-1
更新日期:2017-01-01 00:00:00
abstract::Kidney transplantation provides the best outcome for patients with end-stage renal failure both in terms of morbidity and mortality and health-related quality of life (QoL). Health-related QoL has become recognized as an important outcome measure in patients with different chronic medical conditions, including chronic...
journal_title:International urology and nephrology
pub_type: 杂志文章,评审
doi:10.1007/s11255-009-9527-z
更新日期:2009-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:In diabetics genetic predisposition, poor glycemic control and arterial hypertension contribute to nephropathy development in patients affected by diabetes mellitus. We set up the hypothesis that diabetic nephropathy and incisional hernia formation may have in common alterations of collagen com...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-016-1229-8
更新日期:2016-05-01 00:00:00
abstract:OBJECTIVES:To introduce a novel surgical technique for the reconstruction of distal urethral strictures using buccal mucosal graft (BMG) through a transurethral approach. METHODS:A retrospective institution chart review was conducted of all the patients who underwent a transurethral ventral BMG inlay urethroplasty fro...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-016-1381-1
更新日期:2016-11-01 00:00:00
abstract::Tubular reabsorption of magnesium ( TRMg ) was calculated from the values of plasma ultrafiltrable Mg and urinary Mg in 36 patients with transplanted kidneys. The study revealed a defect in TRMg in all investigated patients. The lowest TRMg values were found in patients with poor function of the transplanted kidneys. ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02082706
更新日期:1984-01-01 00:00:00
abstract::Using the materials of more than 200 scientific papers of recent years in this review it has been carried out analysis of the effectiveness and also discussed the merits and demerits of various methods of treatment of urinary stone diseases (USD). With this purpose, for the first time it has been carried out analysis ...
journal_title:International urology and nephrology
pub_type: 杂志文章,评审
doi:10.1023/a:1015282526252
更新日期:2001-01-01 00:00:00
abstract::Orthostatic hypotension is very common in the elderly. It increases morbidity and is an independant predictor of all cause mortality. It is defined as a fall in systolic blood pressure greater than 20 mm Hg or a fall in diastolic blood pressure greater than 10 mm Hg within 3 minutes of standing. Symptoms include light...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-005-7663-7
更新日期:2005-01-01 00:00:00
abstract::A series of 28 patients with urethral strictures less than 2 cm length underwent 32 visual optical internal urethrotomy under local urethral anesthesia with lidocaine. The procedure was completed successfully in 26 of 28 (92.9%) patients. Among these 25 of 26 (96%) patients reported mild pain. Visual analogue scale (V...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-006-9046-0
更新日期:2007-01-01 00:00:00
abstract:OBJECTIVE:Some studies have found that prostate cancer (PCa) screening provides little or no change in PCa-related mortality during the 7-10 years following diagnoses. However, most men are diagnosed with PCa at low-stage disease and die of unrelated causes during this period. Men diagnosed at stage IV are at much high...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-010-9799-3
更新日期:2011-06-01 00:00:00
abstract::Endometriosis of the urinary tract is a relatively rare condition. Since clinical signs are not specific the diagnosis is difficult and the therapy is not well defined. Two cases and a review of the literature are presented. ...
journal_title:International urology and nephrology
pub_type: 杂志文章,评审
doi:10.1007/BF02551109
更新日期:1997-01-01 00:00:00
abstract:PURPOSE:This study examined whether the laser-capture microdissection (LCM) method can achieve separation of urothelial cells from detrusor cells or superficial urothelial cells from intermediate/basal urothelial cells, using α-smooth muscle actin (SMA) and cytokeratin 20 (CK20). In addition, we investigated the change...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-015-0926-z
更新日期:2015-04-01 00:00:00
abstract:PURPOSE:The present study aimed to evaluate the impact of a filmed research-based drama-Fit for Dialysis-and an exercise program on patients' physical activity and fitness outcomes. METHODS:Nineteen (10 at the intervention site, 9 at the control site) older patients with a medical diagnosis of hemodialysis-dependent e...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-020-02745-y
更新日期:2021-01-02 00:00:00
abstract::We describe a 21-year male with mood disorder on lithium therapy and psoriasis-like skin lesions presenting with rapidly progressive renal failure. The kidney biopsy showed acute tubulointerstitial nephritis with immunoglobulin G4-positive plasma cell infiltration. He was started on oral steroids with a provisional di...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-013-0447-6
更新日期:2014-01-01 00:00:00
abstract::Gleason score has been identified as an important variable to predict disease extent and biologic behaviour of prostate cancer. However, the correlation between Gleason score of needle biopsy and surgical specimen is often poor. We studied 72 patients who underwent needle biopsy and radical prostatectomy to correlate ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02550548
更新日期:1998-01-01 00:00:00
abstract:PURPOSE:To investigate the role of urinary neutrophil gelatinase-induced lipocalin (uNGAL) measurement in the early diagnosis of acute kidney injury that may occur after intraoperative ischemia in patients undergoing partial nephrectomy (PN). METHODS:This prospective study included 86 patients who underwent open lapar...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-020-02660-2
更新日期:2020-09-26 00:00:00
abstract:OBJECTIVE:Recently, we reported that alpha 1A-adrenoceptor (AR) is the main participant in phenylephrine-induced human ureteral contraction. We therefore decided to carry out a prospective randomized study to evaluate the effects of silodosin, a selective alpha 1A AR antagonist, as a medical expulsive therapy (MET) for...
journal_title:International urology and nephrology
pub_type: 杂志文章,随机对照试验
doi:10.1007/s11255-013-0429-8
更新日期:2013-06-01 00:00:00
abstract::Bilateral vasovasostomies were performed in 7 previously vasectomized patients. The method employed was a modification of a one-layer anastomotic technique. There was no correlation between the presence of absence of sperm in the vas fluid, presence or absence of sperm granuloma, and site of vasectomy. No correlation ...
journal_title:International urology and nephrology
pub_type: 临床试验,杂志文章
doi:10.1007/BF02550083
更新日期:1995-01-01 00:00:00
abstract::We report a case of spontaneous perirenal hematoma that developed acutely during an elective coronary angiography in a 65-year-old man with suspected coronary artery disease, probably related to the use of heparin during angiography. The patient did not have any systemic vasculitides and was not receiving antiplatelet...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1023/a:1025982613830
更新日期:2003-01-01 00:00:00