Abstract:
:Gleason score has been identified as an important variable to predict disease extent and biologic behaviour of prostate cancer. However, the correlation between Gleason score of needle biopsy and surgical specimen is often poor. We studied 72 patients who underwent needle biopsy and radical prostatectomy to correlate Gleason score with PSA, clinical and pathological tumour stage. Only 47.2% of Gleason scores were identical in the biopsy and specimens, 37.5% were undergraded and 15.2% were overgraded. Correlations between clinical and pathological stage were identical in 30.5% of patients, 61.1% of patients were understaged and 8.3% overstaged. In conclusion, accuracy of clinical staging and grading of prostate cancer is low. Although the Gleason score on needle biopsy might be useful to predict the final stage and grade, correlation with surgical specimen is poor.
journal_name
Int Urol Nephroljournal_title
International urology and nephrologyauthors
Cecchi M,Minervini R,Sepich CA,Ippolito C,Pagni GL,Summonti D,Di Benedetto A,Fiorentini Ldoi
10.1007/BF02550548subject
Has Abstractpub_date
1998-01-01 00:00:00pages
575-80issue
5eissn
0301-1623issn
1573-2584journal_volume
30pub_type
杂志文章abstract::We report on our experience with a new surgical procedure of forming a pseudoneotesticle from indigenous tissues obtained from the existing scrotal contents. This procedure has been performed in 32 patients with a diagnosis of hormone dependent cancer of the prostate as a therapeutic manoeuvre, and in 3 children who h...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02550317
更新日期:1998-01-01 00:00:00
abstract:OBJECTIVE:Recently, we reported that alpha 1A-adrenoceptor (AR) is the main participant in phenylephrine-induced human ureteral contraction. We therefore decided to carry out a prospective randomized study to evaluate the effects of silodosin, a selective alpha 1A AR antagonist, as a medical expulsive therapy (MET) for...
journal_title:International urology and nephrology
pub_type: 杂志文章,随机对照试验
doi:10.1007/s11255-013-0429-8
更新日期:2013-06-01 00:00:00
abstract::Açai (Euterpe oleracea Mart.) fruit from the Amazon region in Brazil contains bioactive compounds such as α-tocopherol, anthocyanins (cyanidin 3-glycoside and cyanidin 3-rutinoside), and other flavonoids with antioxidant and anti-inflammatory properties. Moreover, the prebiotic activity of anthocyanins in modulating t...
journal_title:International urology and nephrology
pub_type: 杂志文章,评审
doi:10.1007/s11255-018-1912-z
更新日期:2018-12-01 00:00:00
abstract::Sleep disorders for patients on dialysis are significant causes of a poorer quality of life and increased morbidity and mortality. No study has evaluated patients undergoing automated peritoneal dialysis (APD) to assess their sleep disorders compared to hemodialysis (HD) and continuous ambulatory peritoneal dialysis (...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-014-0860-5
更新日期:2015-02-01 00:00:00
abstract:PURPOSE:To assess clinical presentation and outcomes of different treatment strategies in cases of spontaneous renal hemorrhage (SRH). METHODS:A retrospective analysis of patients with SRH between 2000 and 2018 was performed. Patients' demographics, clinical presentation, laboratory and radiological investigations, an...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-019-02333-9
更新日期:2020-03-01 00:00:00
abstract::We report a case of penile incarceration in a 53-year-old impotent man. The base of the penis was encircled by a metal ring in order to achieve better erection. There was marked oedema of the entire penis distal to the constricting ring. The metal ring was removed successfully by cutting it with a steel saw. ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02564752
更新日期:1995-01-01 00:00:00
abstract::The results of an investigation dealing with the therapy of instability of the detrusor using oxybutynin hydrochloride are presented. Out of an unselected group of patients 21 were enrolled in the trial. After therapy 19 patients showed significant improvement of subjective symptoms and objective urodynamic parameters...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02550401
更新日期:1990-01-01 00:00:00
abstract:BACKGROUND:Although sleep complaints are commonly reported in persons with end stage renal disease (ESRD), little is known about the prevalence of sleep complaints in chronic kidney disease (CKD), and the relation of sleep quality to the severity of kidney disease. METHODS:We administered the Kidney Disease Quality of...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-004-4654-z
更新日期:2005-01-01 00:00:00
abstract:BACKGROUND:Contrast-induced nephropathy (CIN) is the major complication related to contrast media administration in patients after coronary angiography (CAG). However, inconsistent results have been published in the literature regarding the effects of pharmacological drugs on CIN prevention. We conducted a network meta...
journal_title:International urology and nephrology
pub_type: 杂志文章,meta分析,评审
doi:10.1007/s11255-018-1814-0
更新日期:2018-06-01 00:00:00
abstract:PURPOSE:To evaluate the surgical feasibility and postoperative cosmesis of a novel transumbilical laparoendoscopic single-site (LESS) surgical approach involving Y-shaped incisions and three-flap umbilicoplasty in urachal remnant patients. METHODS:Patients with symptomatic urachal remnants who underwent either convent...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-020-02746-x
更新日期:2021-01-02 00:00:00
abstract:PURPOSE:Obstructive pyelonephritis is a common urologic emergency that requires prompt decompression of the collecting system. The COVID-19 pandemic has changed patient flow and healthcare strategies at numerous emergency departments across Brazil with still unknown consequences for the population. This study sought to...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-020-02708-3
更新日期:2020-11-21 00:00:00
abstract::In the introduction the author stresses that the main facts which decide the choice and prognosis of therapy are localization, length and the so-called complexity of the stricture. His 15-year material from 388 operations on 290 patients is presented. Circular strictures of the anterior urethra (a total of 135 operati...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02082106
更新日期:1983-01-01 00:00:00
abstract:BACKGROUND:Proteinuric renal diseases are often associated with progressive tubulointerstitial fibrosis that usually defines the degree and rate of progression of renal failure. Glomerular filtration of excess albumin, the dominant protein in proteinuria, into proximal tubule could provide the stimulus to induce certai...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-007-9249-z
更新日期:2007-01-01 00:00:00
abstract:OBJECTIVE:The present study investigated the inhibitory effects of a novel minimally invasive implanted tibial nerve stimulation device on non-nociceptive bladder reflexes in cats. MATERIALS AND METHODS:A wireless minimally invasive implanted nerve stimulator was implanted adjacent to the left tibial nerve in seven ca...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-020-02666-w
更新日期:2020-09-28 00:00:00
abstract:PURPOSE:Symptomatic urachal remnants are rare benign anomalies affecting young adults. For these patients, both curative treatment and acceptable postoperative aesthetic outcomes are important. Here, we describe a novel transumbilical approach, using Y-shaped incisions and three-flap umbilicoplasty techniques, to impro...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-017-1678-8
更新日期:2017-11-01 00:00:00
abstract::Fournier's gangrene (FG) is a rapidly progressive, fulminant infection of the scrotum, perineum and the abdominal wall. FG is caused by synergic aerobic and anaerobic organisms. Modern surgical series report mortality of up to 67%. This originally rare disease has become more frequent. Aggressive treatment including a...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1023/a:1019554327341
更新日期:2001-01-01 00:00:00
abstract:OBJECTIVES:To examine symptomatology and microbiology of infected lymphocele (LC) post-robotic-assisted radical prostatectomy and pelvic lymph node dissection (PLND) and to assess for potential predictors for LC fluid culture positivity. Secondly, to provide general recommendations about use of select antimicrobial the...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-017-1599-6
更新日期:2017-07-01 00:00:00
abstract::When groups of 10 Spontaneously Hypertensive Rats (SHR) were fed diets containing either 1% w/w regular garlic (Allium sativum) (AS) or 1% w/w wild garlic (Allium ursinum) (AU) for 45 days, the final mean systolic blood pressure (SBP) was reduced significantly compared to control (C) (C 189; AS 175; Au 173 mm Hg). Com...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1023/a:1014417526290
更新日期:2001-01-01 00:00:00
abstract::The aim of this report is to emphasize the use of methylene staining test and the Nd:YAG laser in the diagnosis and treatment of premalignant lesions and CIS of the bladder. The use of an appropriate solution of methylene blue (0.2% in 0.9 M NaCl for 15 min) permits the staining of premalignant areas and CIS, and thei...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02559739
更新日期:1989-01-01 00:00:00
abstract::Patients with metastatic prostate cancer respond to androgen withdrawal therapy, but progression to androgen independence is frequently observed. To clarify the predictor of response to endocrine therapy, the role of PSA changes and the prognosis of the patients were evaluated in 115 Japanese cases of prostate cancer ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1023/a:1014410026495
更新日期:2001-01-01 00:00:00
abstract:BACKGROUND:Cardiovascular disease is the most common cause of death in patients with chronic kidney disease (CKD). Epicardial adipose tissue (EAT) is an independent predictor of cardiovascular disease in the general population, and usually increases in the patients with cardiovascular disease risk. The change of EAT in...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-020-02575-y
更新日期:2020-12-01 00:00:00
abstract:PURPOSE:A region of chromosome 22 which includes APOL1 and MYH9 genes was recently identified as a risk locus for non-diabetic forms of kidney disease, including idiopathic and HIV-associated focal segmental glomerular sclerosis and kidney disease clinically attributed to hypertension among African Americans. The purpo...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-012-0263-4
更新日期:2013-04-01 00:00:00
abstract:PURPOSE:Smoking habit is the major risk factor for bladder cancer (BC), related to about 50% of these tumors; however, the tobacco dose-effect impact on BC immune treatment is underexplored. This study evaluates the impact of smoke load on non-muscle invasive bladder cancer (NMIBC) prognosis after intravesical BCG. ME...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-020-02438-6
更新日期:2020-08-01 00:00:00
abstract:PURPOSE:To examine whether platelet-to-lymphocyte ratio (PLR) is associated with 5-year mortality in patients with chronic kidney disease (CKD), we performed this study using data from the National Health and Nutrition Examination Survey (NHANES) through 1999 to 2006. METHODS:3285 patients with CKD stage 1-5 were incl...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-020-02548-1
更新日期:2020-10-01 00:00:00
abstract:PURPOSE:To evaluate the efficacy and safety of the calcineurin inhibitors (CNIs) cyclosporine (CyA) and tacrolimus (TAC) in the induction and maintenance treatment of lupus nephritis (LN). METHODS:The Cochrane library, PubMed, Embase, and CENTRAL databases were searched and reviewed up to February 2015. Randomized con...
journal_title:International urology and nephrology
pub_type: 杂志文章,meta分析,评审
doi:10.1007/s11255-015-1201-z
更新日期:2016-05-01 00:00:00
abstract:BACKGROUND:Several techniques have been used to repair mid-penile hypospadias; however, high failure rates and major complications have been reported. In this study, we describe a novel technique using a well-vascularized flap of the inner and outer preputial skin. METHODS:A total of 110 male children with hypospadias...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-016-1416-7
更新日期:2016-12-01 00:00:00
abstract::Using the materials of more than 200 scientific papers of recent years in this review it has been carried out analysis of the effectiveness and also discussed the merits and demerits of various methods of treatment of urinary stone diseases (USD). With this purpose, for the first time it has been carried out analysis ...
journal_title:International urology and nephrology
pub_type: 杂志文章,评审
doi:10.1023/a:1015282526252
更新日期:2001-01-01 00:00:00
abstract:BACKGROUND:There is evidence that chronic local ischemia may be one possible etiology of prostatic atrophy (PA). Our aim was to study the expression of hypoxia induced factors in areas of PA. DESIGN:The immunohistochemical expression of hypoxia-inducible factor-1 alpha (HIF-1) and vascular endothelial growth factor (V...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-006-6657-4
更新日期:2006-01-01 00:00:00
abstract:PURPOSE:Non-adherence (NA) to medication is a major contributor to treatment failure in hypertensive patients. Factors of the ecological model, at family/healthcare professional, service, and system levels, are rarely evaluated as correlates of NA in hypertensive patients. METHODS:This crossectional study assessed the...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-020-02755-w
更新日期:2021-01-16 00:00:00
abstract:PURPOSE:Physical inactivity and sleep disturbance are frequently observed and relate to poor clinical outcomes in maintenance hemodialysis patients. We aimed to investigate the effect of intradialytic exercise on daily physical activity and sleep quality, measured by an accelerometer, in maintenance hemodialysis patien...
journal_title:International urology and nephrology
pub_type: 杂志文章,随机对照试验
doi:10.1007/s11255-018-1796-y
更新日期:2018-04-01 00:00:00