Abstract:
BACKGROUND:Several techniques have been used to repair mid-penile hypospadias; however, high failure rates and major complications have been reported. In this study, we describe a novel technique using a well-vascularized flap of the inner and outer preputial skin. METHODS:A total of 110 male children with hypospadias underwent repair by our technique between 2008 and 2015. The inclusion criteria were children with mid-penile or slightly more proximal hypospadias, with or without ventral chordae, and an intact prepuce of the cobra eyes variety. Recurrent cases, patients with other preputial types, and circumcised children were excluded from this study. The prepared flap was sutured in its natural longitudinal orientation to the created urethral plate strip to form a neo-urethra over a urethral catheter. Outcome measures included surgical success without the formation of a urethra-cutaneous fistula, no ischaemia of the flaps, glans dehiscence or infection and functional outcome and cosmetic appearance. RESULTS:The median follow-up duration was 3.3 years. There were 63 cases of mid-penile hypospadias (57.3 %), and in 47 cases (42.7 %), the meatus was slightly more proximal. The age of the patients ranged from 1.1 to 8.0 years, with a mean age of 4.6 ± 1.2 years. Surgery was successful in 106 (96.4 %) cases. Minor complications occurred in 11 patients (10 %) and included oedema of glans in ten patients and bluish discoloration on the ventral aspect of the glans close to the suture line in three patients. All patients improved within 2 weeks after surgery. Long-term follow-up revealed a properly functioning urethra with a forward, projectile, single, compact, and rifled urinary stream of adequate calibre and cosmetically acceptable repair. No cases of meatal retraction, meatal stenosis, urethral stricture, or acquired urethral diverticulum occurred. DISCUSSION:Our technique is different from the split prepuce in situ technique. We create a narrow strip of the urethral plate that facilitates glanular closure, and we use the inner and adjacent outer skin in a vertical manner to preserve excess skin for penile coverage. Prepuce is split at midline to preserve more preputial skin with favourable dartos tissue for penile skin coverage. The glans is closed using a stitch-by-stitch method that has not been described previously. CONCLUSION:This study presents a novel technique for mid-penile hypospadias repair using a preputial skin flap with excellent results in terms of short- and long-term outcomes.
journal_name
Int Urol Nephroljournal_title
International urology and nephrologyauthors
Elmoghazy H,Hussein MM,Mohamed E,Badawy A,Alsagheer G,Abd Elhamed AMdoi
10.1007/s11255-016-1416-7subject
Has Abstractpub_date
2016-12-01 00:00:00pages
1943-1949issue
12eissn
0301-1623issn
1573-2584pii
10.1007/s11255-016-1416-7journal_volume
48pub_type
杂志文章abstract::Renal arterial embolization and subsequent nephrectomy or nephrectomy alone were performed in 34 patients with renal cell carcinoma. Renal arterial embolization caused a blood pressure elevation concomitant with an increase in plasma renin activity (PRA), urinary aldosterone excretion or urinary prostaglandin (PGE2) e...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02549489
更新日期:1988-01-01 00:00:00
abstract::Nephroblastoma (Wilms' tumour) is very rarely found in adult patients. We report on 10 cases to demonstrate the diagnostic and therapeutic problems. In case of flank pain, large tumour mass, fast tumour growth and young age, the possibility of Wilms' tumour should be taken into consideration even in adult patients. Th...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02550952
更新日期:1996-01-01 00:00:00
abstract:PURPOSE:To assess clinical presentation and outcomes of different treatment strategies in cases of spontaneous renal hemorrhage (SRH). METHODS:A retrospective analysis of patients with SRH between 2000 and 2018 was performed. Patients' demographics, clinical presentation, laboratory and radiological investigations, an...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-019-02333-9
更新日期:2020-03-01 00:00:00
abstract::Search is under way to develop reliable tests for the prediction of stone risk. Several indices and ratios on the basis of urinary excretions have been suggested. In the present study the applicability of some risk indices and ratios in slum dwellers of Dharavi area of Bombay was examined. No significant difference wa...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02550432
更新日期:1990-01-01 00:00:00
abstract:BACKGROUND:Although sleep complaints are commonly reported in persons with end stage renal disease (ESRD), little is known about the prevalence of sleep complaints in chronic kidney disease (CKD), and the relation of sleep quality to the severity of kidney disease. METHODS:We administered the Kidney Disease Quality of...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-004-4654-z
更新日期:2005-01-01 00:00:00
abstract::The first time in Scandinavia we present a case report of a pure primary low-grade neuroendocrine carcinoma (carcinoid tumor) of the prostate. Our patient is a 34-year-old male with a long history of symptomatic chronic prostatitis/prostatodynia. After developing severe obstructive uropathy, a transurethral resection ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-009-9660-8
更新日期:2010-09-01 00:00:00
abstract:AIM:Chronic prostatitis (CP) and chronic pelvic pain syndrome (CPPS) is a common disabling condition that is primarily associated with pain in the urogenital region and disturbances in urinary and sexual function. Chronic pelvic pain symptoms are the most common presentation, especially perineal, lower abdominal, testi...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-010-9809-5
更新日期:2011-06-01 00:00:00
abstract::To compare the two conventional surgical methods for varicocelectomy, 50 patients with varicocele were operated by using either the retroperitoneal or the inguinal techniques. Compliance with local anaesthesia was found to be poor in the retroperitoneal group. The operative time was significantly shorter (p = 0.00038)...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02768286
更新日期:1994-01-01 00:00:00
abstract::Insulin resistance (IR) and secondary hyperinsulinaemia are major risk factors of atherosclerosis and probably also of related glomerulosclerosis. Angiotensin converting enzyme inhibitors (ACEI), while improving IR in essential hypertension, do not improve it in patients with chronic renal disease. Thus, the combinati...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02551119
更新日期:1997-01-01 00:00:00
abstract:INTRODUCTION:Hand-assisted laparoscopy was first performed in the 1990s by inserting the surgeon's finger or hand through a small tight wound. Although leakage of gas from the incision initially limited the usefulness of the technique, the hand-assisted procedures have advanced extensively since the introduction of the...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-006-9027-3
更新日期:2007-01-01 00:00:00
abstract:AIM:Skin test anergy is common in patients with uremia and during maintenance hemodialysis treatment. However, up to date only one study concerning skin test in peritoneal dialysis patients has focused on the issue. Our cross-sectional controlled study was conducted to analyze the correlation of purified protein deriva...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-020-02467-1
更新日期:2020-06-01 00:00:00
abstract:PURPOSE:Anaemia and resistance to erythropoiesis-stimulating agents (ESAs) are common complications in haemodialysis (HD) patients. We investigated the role of hepcidin in the development of anaemia and ESA resistance/hyporesponsiveness and its relation to the plasma levels of the inflammatory markers interleukin 6 (IL...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-018-2062-z
更新日期:2019-02-01 00:00:00
abstract::The white blood cell count (WBC) decreases during haemodialysis and it was investigated as a function of different dialysis membranes. Each of them was used four times, applying different sterilization methods. Twelve chronic haemodialysis patients were studied and dialysed with cuprophan and polyacrylonitrile (PAN) m...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02082704
更新日期:1984-01-01 00:00:00
abstract::During transurethral electroresection in the posterolateral bladder neck, trigone and posterior urethra, unintentional contractions of the thigh-adductor muscles may occur due to irritation of the obturator nerve. The sudden displacement of the bladder wall against the cutting loop may cause a perforation of the bladd...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02085445
更新日期:1983-01-01 00:00:00
abstract:OBJECTIVE:Hemodialysis (HD) patients are at risk of deficiency of essential trace elements and excess of toxic trace elements. The aim of the study was to evaluate the relation between the serum levels of some trace elements and heavy metals (iron, zinc, manganese, copper, magnesium, cobalt, cadmium, and lead) and endo...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-011-0055-2
更新日期:2012-10-01 00:00:00
abstract::Between 1985 and 1989, 54 boys underwent a MAGPI procedure. Excellent cosmetic and functional results were achieved in 94% of our cases in the early period. In order to assess the long-term results of this procedure, 41 boys attended long-term re-evaluation between 6 and 40 (mean 29) months postoperatively. MAGPI was ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02549850
更新日期:1991-01-01 00:00:00
abstract::Hydatid disease of the urinary tract is very rare. We report a case of pure renal hydatid cyst, with its clinical presentation and management. ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02551409
更新日期:1997-01-01 00:00:00
abstract::Semen analysis and immunofluorescent antisperm antibodies were tested in 65 patients with varicocele. The mean sperm count and motility values in our study were 36.8 +/- 2.9 million per ml and 38.4 +/- 2.5 per cent, respectively. Both parameters were found not to differ significantly in three grades of varicocele. Imm...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02089408
更新日期:1985-01-01 00:00:00
abstract::A 40-year-old man was referred to our hospital with gynecomastia and painless swelling of the right scrotum. Ultrasonography revealed a 15 x 10 mm mass with low echogenicity of the right testis. We performed right high orchiectomy. Histologically, Reinke's crystals and capsular invasion by tumor cells were found. Fina...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-006-6661-8
更新日期:2006-01-01 00:00:00
abstract::We have been using the flexible cystoscope since 1987. Detailed information is given concerning the technique of flexible cystoscopy, its indications, advantages and disadvantages. A comparison is made with the results obtained using the rigid cystoscope in an initial series of 100 patients, yielding false negative re...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02549531
更新日期:1992-01-01 00:00:00
abstract::The new microsurgical techniques, tubule and loop intussusception, are compared to end-to-end and side-to-end in an experimental rat model. Sixty adult male Sprague-Dawley rats were operated on bilaterally under the same conditions. The four microsurgical techniques differ in approach to the inner mucosal layer, while...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:
更新日期:1993-01-01 00:00:00
abstract::Sickle cell nephropathy is a major complication of sickle cell disease. It manifests in different forms, including glomerulopathy, proteinuria, hematuria, and tubular defects, and frequently results in end-stage renal disease (ESRD). Different pathophysiologic mechanisms have been proposed to explain the development o...
journal_title:International urology and nephrology
pub_type: 杂志文章,评审
doi:10.1007/s11255-018-1803-3
更新日期:2018-06-01 00:00:00
abstract::This study presents a view of the knowledge the authors have gathered during 11 years of work with radioisotope examinations of the kidneys and ureteral urine passage performed in 34 children. As an important indication field they consider the conditions where excretory urography or separate functional examination, re...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02217144
更新日期:1980-01-01 00:00:00
abstract:PURPOSE:Type 2 diabetes mellitus (T2DM) patients treated with metformin are predisposed to develop contrast-induced nephropathy (CIN) after received emergency contrast-enhanced computed tomography (CT) examination. We evaluated the protective effects of alprostadil on CIN in T2DM patients treated with metformin after c...
journal_title:International urology and nephrology
pub_type: 杂志文章,随机对照试验
doi:10.1007/s11255-017-1639-2
更新日期:2017-11-01 00:00:00
abstract::Infertility may occur in patients with unilateral testicular torsion whose contralateral testis is intact. Depending on this observation, the physicians have begun to examine the contralateral testis. In the present prospective study we aimed to examine the histopathologic alterations occurring in the contralateral te...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02550935
更新日期:1997-01-01 00:00:00
abstract:OBJECTIVE:PlasmaKinetic electrode, holmium laser, green laser and Nd: YAG laser have been used for treating benign prostate hyperplasia (BPH). To compare the pathological changes of thermal injury by these different devices. MATERIAL AND METHODS:Tissues donated by several male patients with prostate cancer who have wr...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-020-02723-4
更新日期:2021-01-22 00:00:00
abstract:BACKGROUND:Recently, great progress has been made in understanding the pathogenesis of membranous nephropathy (MN) with the discovery of autoantibodies (Abs) to M-type phospholipase A2 receptor (PLA2R) in serum and in immunocomplexes deposited in glomerulus in most adult patients with primary MN. OBJECTIVE:To evaluate...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-020-02682-w
更新日期:2020-10-31 00:00:00
abstract:PURPOSE:Sodium restriction is important for the management of chronic kidney disease (CKD). The present study evaluated the factors impacting dietary sodium restriction in a cohort of Chinese patients with CKD. METHODS:A questionnaire on dietary sodium restriction was administered to patients with non-dialysis CKD who...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-016-1223-1
更新日期:2016-05-01 00:00:00
abstract::The development of a reno-jejunal fistula following a Roux-en-Y cystojejunostomy for an incorrectly diagnosed pancreatic pseudocyst is described. Up to now, this is the second case of iatrogenic reno-jejunal fistula reported in literature. Reno-jejunal fistulas are exceedingly rare and are usually consequences of urol...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1023/a:1007115605427
更新日期:1999-01-01 00:00:00
abstract::Most of the purported links between microbial agents and primary small-vessel anti-neutrophilic antibody-positive (ANCA) vasculitides remain speculative. There is strong circumstantial evidence for the role of Staphylococcus aureus in the development of Wegener's granulomatosis, but its role in other ANCA-positive vas...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-009-9652-8
更新日期:2010-09-01 00:00:00