Abstract:
:Platinum (Pt) concentrations in the kidney and liver were determined in 12 autopsied cases following cisplatin treatment. The Pt level in the liver was generally higher than that in the kidney. Pt concentration in the liver showed a significant correlation with the total dose of cisplatin. However, no dose-dependent Pt accumulation was observed in the kidney. Kidney Pt levels were correlated with the doses of cisplatin injected within a 6-month period prior to the patient's death. It is suggested that the dose of cisplatin injected during a relatively short period before the patient's death affected the Pt concentration in the kidney.
journal_name
Int Urol Nephroljournal_title
International urology and nephrologyauthors
Uozumi J,Ueda T,Yasumasu T,Koikawa Y,Naito S,Kumazawa J,Sueishi Ksubject
Has Abstractpub_date
1993-01-01 00:00:00pages
215-20issue
3eissn
0301-1623issn
1573-2584journal_volume
25pub_type
杂志文章abstract:PURPOSE:To investigate the effect of intradialytic resistance exercise on inflammation markers and sarcopenia indices in maintenance hemodialysis (MHD) patients with sarcopenia. METHODS:Forty-one MHD patients with sarcopenia were divided into an intervention group (group E, n = 21) and a control group (group C, n = 20...
journal_title:International urology and nephrology
pub_type: 杂志文章,随机对照试验
doi:10.1007/s11255-019-02200-7
更新日期:2019-08-01 00:00:00
abstract::One hundred patients with recurrent calcium nephrolithiasis were submitted to the Pak test. At fasting state hypercalciuria was found in 27 cases, while a group of 16 further patients became hypercalciuric after oral calcium load. Only measurement of urinary cAMP excretion in both conditions made it possible to diagno...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02083499
更新日期:1985-01-01 00:00:00
abstract::Observations with diagnostic ultrasound in renal disease over a 10-year period are reviewed. The advantages of diagnostic methods involving the least possible discomfort to the patient are emphasized. Ultrasonography is regarded as a reliable non-invasive method for the diagnostic differentiation between renal tumours...
journal_title:International urology and nephrology
pub_type: 杂志文章,评审
doi:10.1007/BF02083009
更新日期:1983-01-01 00:00:00
abstract::Bilateral vasovasostomies were performed in 7 previously vasectomized patients. The method employed was a modification of a one-layer anastomotic technique. There was no correlation between the presence of absence of sperm in the vas fluid, presence or absence of sperm granuloma, and site of vasectomy. No correlation ...
journal_title:International urology and nephrology
pub_type: 临床试验,杂志文章
doi:10.1007/BF02550083
更新日期:1995-01-01 00:00:00
abstract:PURPOSE:No safe ultrasound (US) parameters have been established to differentiate the causes of graft dysfunction. OBJECTIVES:To define US parameters and identify the predictors of normal graft evolution, delayed graft function (DGF), and rejection at the early period after kidney transplantation. METHODS:Between Jun...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-014-0896-6
更新日期:2015-02-01 00:00:00
abstract:PURPOSE:Cardiovascular (CV) events are the first cause of death in patients with chronic renal disease (CKD) and in patients with type 2 diabetes mellitus (DM2). The combination of CKD and DM2 elevates the risk of both cardiovascular disease (CVD) and death in this high-risk population. Besides traditional risk factors...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-017-1755-z
更新日期:2018-02-01 00:00:00
abstract:PURPOSE:Cardiovascular calcifications (CVC) are present in up to 70% of non-diabetic dialysis patients. Sparse data are available on predictors of very long-term outcomes of such patients. The Belgrade Aachen Study on Calcification in Hemodialysis patients (BASCH study) aimed to study this using a comprehensive CVC ass...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-018-1821-1
更新日期:2018-05-01 00:00:00
abstract:BACKGROUND:There is evidence that chronic local ischemia may be one possible etiology of prostatic atrophy (PA). Our aim was to study the expression of hypoxia induced factors in areas of PA. DESIGN:The immunohistochemical expression of hypoxia-inducible factor-1 alpha (HIF-1) and vascular endothelial growth factor (V...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-006-6657-4
更新日期:2006-01-01 00:00:00
abstract::Fifty-eight patients with urate calculi and 31 patients with other (non-urate) calculi were examined for total-body potassium by means of a total-body counter. The patients with urate calculosis were found to differ significantly in their total-body K from patients with other calculi as well as from normal subjects. T...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02082228
更新日期:1979-01-01 00:00:00
abstract:PURPOSE:Hypovitaminosis D is common in chronic kidney disease (CKD) and is associated with endothelial dysfunction and cardiovascular events. This study aimed to investigate the effects of vitamin D supplementation on endothelial dysfunction in non-dialysis CKD patients. MATERIALS AND METHODS:Seventy-one non-dialysis ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-018-1829-6
更新日期:2018-05-01 00:00:00
abstract:BACKGROUND:Parental iron is used to optimize hemoglobin and enhance erythropoiesis in end-stage renal disease along with erythropoietin-stimulating agents. Safety of iron has been debated extensively and there is no definite evidence whether parenteral iron increases the risk of infections and mortality. We performed t...
journal_title:International urology and nephrology
pub_type: 杂志文章,meta分析
doi:10.1007/s11255-019-02273-4
更新日期:2019-10-01 00:00:00
abstract::Immunosuppressed recipients of organ transplants have a higher incidence of carcinoma than the general population. A retrospective analysis was made at the Department of Urology of Bonn University, investigating 236 renal allograft recipients as to the incidence of neoplasms before and after transplantation. Eleven pa...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02552189
更新日期:1997-01-01 00:00:00
abstract::We aimed to investigate whether high peripheral and cavernosal plasma levels of apolipoprotein-(a) [Lp (a)] is an indicator for vasculogenic erectile dysfunction. We determined Lp (a), total cholesterol (TC), triglyceride (TG) and high density lipoprotein (HDL) levels in peripheral and cavernosal blood in 39 patients ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02550575
更新日期:1998-01-01 00:00:00
abstract::Sleep disorders for patients on dialysis are significant causes of a poorer quality of life and increased morbidity and mortality. No study has evaluated patients undergoing automated peritoneal dialysis (APD) to assess their sleep disorders compared to hemodialysis (HD) and continuous ambulatory peritoneal dialysis (...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-014-0860-5
更新日期:2015-02-01 00:00:00
abstract:OBJECTIVES:According to current guidelines, radical cystectomy (RC) should be combined with an extended pelvic lymphadenectomy (PLND) as therapeutic and staging instrument. Objective of this study was to analyze the influence of PLND on survival rates and complication rates in a selected group of elderly patients with ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-017-1699-3
更新日期:2017-12-01 00:00:00
abstract::During a 3-year period, hundreds of patients underwent ESWL treatment with the Dornier HM-3 and HM-4 lithotriptors operating at our institution. Our experience in 3,500 patients treated with the HM-4 bath-free lithotriptor is reported. Patients with radiolucent or cystine stones, stones larger than 3 cm or staghorn ca...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02551334
更新日期:1997-01-01 00:00:00
abstract:BACKGROUND:Estimation of the glomerular filtration rate (GFR) is required in the assessment of patients with chronic kidney disease (CKD) in order to provide information regarding the functional status of the kidneys. Current guidelines advocate the use of prediction equations, such as the Cockcroft-Gault (CG) formula ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-008-9515-8
更新日期:2009-01-01 00:00:00
abstract::A total of 56 patients with haemospermia were reviewed. Twenty-four patients suffered from prolonged haemospermia for more than 1 month or recurrent haemospermia (refractory group). In 32 patients haemospermia disappeared within a month (non-refractory group). Patient age in the refractory group was significantly high...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02564772
更新日期:1995-01-01 00:00:00
abstract:PURPOSE:A region of chromosome 22 which includes APOL1 and MYH9 genes was recently identified as a risk locus for non-diabetic forms of kidney disease, including idiopathic and HIV-associated focal segmental glomerular sclerosis and kidney disease clinically attributed to hypertension among African Americans. The purpo...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-012-0263-4
更新日期:2013-04-01 00:00:00
abstract::A 67-year-old Saudi man with poorly controlled diabetes-mellitus underwent orchiectomy for a painful left testicular swelling that did not respond to antibiotics. Clinical diagnosis was testicular malignancy. Histologic workup demonstrated extensive involvement of the testis and epididymis by diffuse infiltrate of lar...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-009-9674-2
更新日期:2010-09-01 00:00:00
abstract:OBJECTIVE:The purpose was to evaluate the efficacy of the addition of short-term desmopressin to enuretic alarm in patients with primary monosymptomatic nocturnal enuresis (PMNE). MATERIALS AND METHODS:A total of 58 [corrected] children with PMNE were included in this study. The patients were randomized into two group...
journal_title:International urology and nephrology
pub_type: 杂志文章,随机对照试验
doi:10.1007/s11255-008-9355-6
更新日期:2008-01-01 00:00:00
abstract:OBJECTIVES:To examine the survival effect of treatment delays from the time of confirmed diagnosis of prostate cancer to first treatment in an Australian population. METHODS:Three thousand one hundred and forty patients were identified from the South Australian Prostate Cancer Clinical Outcomes Collaborative database ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-017-1508-z
更新日期:2017-03-01 00:00:00
abstract:PURPOSE:To evaluate the efficacy and safety of the calcineurin inhibitors (CNIs) cyclosporine (CyA) and tacrolimus (TAC) in the induction and maintenance treatment of lupus nephritis (LN). METHODS:The Cochrane library, PubMed, Embase, and CENTRAL databases were searched and reviewed up to February 2015. Randomized con...
journal_title:International urology and nephrology
pub_type: 杂志文章,meta分析,评审
doi:10.1007/s11255-015-1201-z
更新日期:2016-05-01 00:00:00
abstract:PURPOSE:Uremic toxins produced by gut microbiota (indoxyl sulfate-IS, p-cresyl sulfate-p-CS, and indole-3-acetic acid-IAA) accumulate in hemodialysis (HD) patients and exhibit potent inflammatory effects. However, the impact of these toxins on nuclear E2-related factor 2 (Nrf2) and nuclear factor-kappa B (NF-κB) expres...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-017-1748-y
更新日期:2018-02-01 00:00:00
abstract::Osmotic diuresis results from urine loss of large amounts of solutes distributed either in total body water or in the extracellular compartment. Replacement solutions should reflect the volume and monovalent cation (sodium and potassium) content of the fluid lost. Whereas the volume of the solutions used to replace lo...
journal_title:International urology and nephrology
pub_type: 杂志文章,评审
doi:10.1007/s11255-018-1822-0
更新日期:2018-07-01 00:00:00
abstract::When a transfusion of packed red blood cells is given, the net potassium load results from lysis of some cells and absorption of potassium by surviving cells. Potassium load was calculated which results from administration of 1 unit (200 cc.) of packed RBC and also that resulting from administration of sufficient pack...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02082677
更新日期:1975-01-01 00:00:00
abstract:PURPOSE:In the present study we have performed a correlation of the most prevailing clinical conditions of multiple sclerosis (MS) with overall drug response and the grade of the disease. MATERIALS AND METHODS:One hundred and ten patients were consecutively and prospectively studied with a clinical syndrome of MS, ran...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1023/a:1017597016622
更新日期:2001-01-01 00:00:00
abstract:OBJECTIVE:We describe a new technique that can easily be used as a tension-free practical alternative in closing the renal defects resulting after open partial nephrectomy (PN). METHODS:A new technique (called "lipocorticoplasty") where "wrapped fatty tissue" was placed in the tumor crater to close the renal defects t...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-011-9899-8
更新日期:2011-09-01 00:00:00
abstract::Forty-two young men with abacterial prostatitis underwent physical examination, semen analyses, rectal US (TRUS) and magnetic resonance imaging (MRI) of the pelvis. Findings on TRUS showed no distinct differences like capsular irregularity, dilatation of the seminal vesicles and calcified foci in the prostate. In MRI ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02550227
更新日期:1998-01-01 00:00:00
abstract::Ureteric stents, a good solution to many urologic problems, can lead to significant morbidity if left in situ longer than required. Our case is that of an elderly male with a history of intractable hypertension presenting with urosepsis, anemia, diabetes and chronic renal failure. His work-up revealed a stent in the r...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-004-0021-3
更新日期:2005-01-01 00:00:00