Abstract:
BACKGROUND:Estimation of the glomerular filtration rate (GFR) is required in the assessment of patients with chronic kidney disease (CKD) in order to provide information regarding the functional status of the kidneys. Current guidelines advocate the use of prediction equations, such as the Cockcroft-Gault (CG) formula and the Modification of Diet in Renal Disease (MDRD) study-derived equations, over clearance of endogenous creatinine (Ccr) in achieving this aim. We were interested in knowing the accuracy of these equations in predicting the GFR in adult Nigerians with CKD. METHODS:We conducted a review of records of patients who were evaluated for CKD at the Nephrology Clinic of the Jos University Teaching Hospital between 2001 and 2003. We compared the CG and MDRD equations against the Ccr in predicting the GFR in 130 patients (88 males and 42 females) with CKD. RESULTS:The means +/- standard deviation (SD) for the measured and predicted GFR by the CG and MDRD equations were similar (17.6 +/- 25.8 ml/min, 19.9 +/- 24.0 ml/min and 21.5 +/- 28.2 ml/min, respectively; analysis of variance [ANOVA], F = 0.68, P = 0.5). The mean difference between CG and Ccr was -2.2 +/- 14.8 ml/min, with discordance at Ccr values >25 ml/min. The mean difference between MDRD and Ccr was -3.9 +/- 18.1 ml/min, with discordance at Ccr values >40 ml/min. CONCLUSION:The CG and MDRD equations provide reliable alternatives to measured Ccr in the estimation of the GFR in Nigerian patients with CKD.
journal_name
Int Urol Nephroljournal_title
International urology and nephrologyauthors
Agaba EI,Wigwe CM,Agaba PA,Tzamaloukas AHdoi
10.1007/s11255-008-9515-8subject
Has Abstractpub_date
2009-01-01 00:00:00pages
635-42issue
3eissn
0301-1623issn
1573-2584journal_volume
41pub_type
杂志文章abstract:OBJECTIVES:Uroepithelium repair has always been the subject of discussion in urology surgeries. Using human amniotic membrane allograft has already proved to be useful in other fields. In this study, we use amniotic membrane to repair uroepithelium injuries in rabbits. METHODS:Twenty healthy rabbits underwent surgery ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-009-9532-2
更新日期:2009-12-01 00:00:00
abstract::The best "treatment" of acute kidney injury (AKI) is prevention. Patients who are at high risk of AKI should have an assessment of their volume status and receive appropriate volume expansion. The most effective type of intravenous fluid remains unclear. Innumerable studies have compared sodium bicarbonate and isotoni...
journal_title:International urology and nephrology
pub_type: 社论,评审
doi:10.1007/s11255-014-0820-0
更新日期:2015-02-01 00:00:00
abstract:AIMS:Erectile dysfunction (ED) is a major care problem worldwide. Tadalafil and sildenafil are the two most common phosphodiesterase 5 inhibitors used to treat ED. This systematic review and meta-analysis were conducted to directly compare tadalafil with sildenafil for the treatment of ED. METHODS:We designed a strate...
journal_title:International urology and nephrology
pub_type: 杂志文章,meta分析,评审
doi:10.1007/s11255-017-1644-5
更新日期:2017-10-01 00:00:00
abstract:PURPOSE:Varicocele is among the leading causes of male infertility. Despite decades of research, its pathogenesis is still unclear. S100A12 is a member of the S100 family of calcium-binding proteins with principal extracellular activities. It is secreted by activated neutrophils and interacts with the multiligand recep...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-015-1188-5
更新日期:2016-03-01 00:00:00
abstract::We describe and report two cases of bilateral symptomatic ureterocele with calculi in two young adult women. They were successfully managed endoscopically by a transverse meatotomy and stone extraction done bilaterally in a single operative session. The 6th month postoperative voiding cystourethrogram showed no reflux...
journal_title:International urology and nephrology
pub_type: 杂志文章,评审
doi:10.1007/s11255-006-0091-5
更新日期:2007-01-01 00:00:00
abstract::Penile cancer is an uncommon disease in the industrialized world that most frequently presents at low stage and is cured with treatment of local and regional surgery. In cases of advanced cancer, the use of more aggressive surgical techniques and the addition of adjuvant therapy may be warranted. So far, few agents ha...
journal_title:International urology and nephrology
pub_type: 杂志文章,评审
doi:10.1007/s11255-011-0011-1
更新日期:2012-02-01 00:00:00
abstract::We report the unusual case of a patient with G3 pT1 transitional cell carcinoma (TCC) of the bladder, which was treated with repeated transurethral resection and maintenance intravesical Bacillus Calmette-Guérin (BCG) therapy. At 30 months follow-up, a symptomatic, solitary iliac lymph node mass was identified and bio...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-007-9187-9
更新日期:2007-01-01 00:00:00
abstract:INTRODUCTION:To find the most beneficial method, we assessed patient comfort and morbidity rates during prostate biopsy procedures performed using periprostatic nerve blockade, unilateral pudendal nerve blockade, intrarectal lidocaine gel, and a combination of periprostatic nerve blockade and intrarectal lidocaine gel....
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-007-9237-3
更新日期:2008-01-01 00:00:00
abstract::A total of 234 patients with chronic glomerulonephritis, detected on the basis of clinical, immunological and pathomorphological criteria, have been examined. A group of 23 chronic glomerulonephritis patients with massive deposits of immunoglobulin A found by immunofluorescent examination, has been separated on the ba...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02085414
更新日期:1985-01-01 00:00:00
abstract::The vaginal influx during miction is a frequent phenomenon. In our clinical study it showed a rate of 54 per cent. The significance of pathomorphological substrates is diminishing with the advancing vesical descensus. The posture during miction has but little influence on the vaginal deviation of the urinary stream. T...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02086819
更新日期:1979-01-01 00:00:00
abstract:AIM:Chronic prostatitis (CP) and chronic pelvic pain syndrome (CPPS) is a common disabling condition that is primarily associated with pain in the urogenital region and disturbances in urinary and sexual function. Chronic pelvic pain symptoms are the most common presentation, especially perineal, lower abdominal, testi...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-010-9809-5
更新日期:2011-06-01 00:00:00
abstract:PURPOSE:To compare the performance of prostate-specific antigen (PSA) density in the diagnosis of prostate cancer in obese and non-obese Chinese men. METHODS:The results of transrectal ultrasound-guided (TRUS) prostate biopsies of Chinese men with PSA <20 ng/mL were reviewed. Parameters including age, body mass index ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-014-0826-7
更新日期:2014-12-01 00:00:00
abstract:PURPOSE:Non-adherence (NA) to medication is a major contributor to treatment failure in hypertensive patients. Factors of the ecological model, at family/healthcare professional, service, and system levels, are rarely evaluated as correlates of NA in hypertensive patients. METHODS:This crossectional study assessed the...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-020-02755-w
更新日期:2021-01-16 00:00:00
abstract::It is well known that some antibiotics are particularly nephrotoxic. In the present study we investigated kidney function and AAP excretion (as an index of nephrotoxicity) in patients with urinary tract infection treated with CAZ or CTX plus TOB. The main cause of infection was E. coli in both treated groups. After 10...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02550604
更新日期:1988-01-01 00:00:00
abstract::The aim of this study was to investigate the hormonal and hemodynamic changes during percutaneous nephrolithotomy (PCNL) procedure. Twenty-one patients between 15-65 years of age were included in the study. Invasive blood pressure and heart rate were monitored during PCNL. Serum sodium, potassium, BUN and creatinine l...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1023/a:1017527126481
更新日期:2001-01-01 00:00:00
abstract::We report a 40-year-old lady who presented with severe headaches, persistent microscopic haematuria and hypertension requiring anti-hypertensive medication. Investigations for secondary hypertension were all normal except for a CT scan. This indicated a complex cystic lesion, measuring 2.4 x 5 x 10 cms , arising from ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-006-9085-6
更新日期:2007-01-01 00:00:00
abstract:OBJECTIVES:To assess whether conservative treatment of pediatric patients with neurogenic detrusor overactivity (NDO) results in lower bladder pressure and increased expected bladder volume (EBV), we investigated the clinical and urodynamic effects of long-term intravesical oxybutynin instillation compared with a stand...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-011-0030-y
更新日期:2012-04-01 00:00:00
abstract:OBJECTIVE:To assess the effectiveness of stepwise extracorporeal shock wave lithotripsy in the treatment of upper urinary stones in childhood. PATIENTS AND METHODS:Between August 1998 and August 2003, 31 patients were treated for renal or ureteric stones. All treatments were performed with Dornier Compact Delta lithot...
journal_title:International urology and nephrology
pub_type: 临床试验,杂志文章
doi:10.1007/s11255-005-4971-x
更新日期:2006-01-01 00:00:00
abstract:AIM:The aim of this study is to assess whether the haemostatic markers D-dimer, factor VIII (FVIII) and von Willebrand factor (VWF) are predictive of non-dipping status in treated hypertensive patients; so, as easy available laboratory data can predict non-dipping pattern and help with the selection of the patients who...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-012-0288-8
更新日期:2013-06-01 00:00:00
abstract::Peripheral PRA was examined in 11 patients with graft artery stenosis after the onset and throughout the course of hypertension. In the acute stage PRA was elevated in 9 patients and decreased to normal in the later stage of hypertension in all but 1 patient with malignant hypertension. The findings suggest that the d...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02082428
更新日期:1981-01-01 00:00:00
abstract::To compare the anti-inflammatory effectiveness of corticotherapy and nonsteroid anti-inflammatory drugs (NSAID), we examined 126 infertile men with infectious aetiology. Seventy-seven patients were on corticotherapy and antibiotherapy (thirty-eight patients on high-dose and thirty-nine patients on low-dose corticother...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1023/a:1007184125900
更新日期:1999-01-01 00:00:00
abstract::El-Far and Sobh were the first to describe abnormalities in porphyrin metabolism in Egyptian patients with chronic renal failure (CRF). Our results were confirmed by others. The present investigation aims to study and discuss the nature of those abnormalities and changes in porphyrin metabolism in CRF patients followi...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02583996
更新日期:1991-01-01 00:00:00
abstract::Tubular reabsorption of magnesium ( TRMg ) was calculated from the values of plasma ultrafiltrable Mg and urinary Mg in 36 patients with transplanted kidneys. The study revealed a defect in TRMg in all investigated patients. The lowest TRMg values were found in patients with poor function of the transplanted kidneys. ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02082706
更新日期:1984-01-01 00:00:00
abstract:OBJECTIVES:To prospectively evaluate the new medical device Transurethral Suprapubic endo-Cystostomy (T-SPeC(®)), used for suprapubic catheter (SPC) placement via the transurethral (inside-to-out) approach, and examine the 30-day outcomes in the first US series. METHODS:IRB approval was obtained for this prospective s...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-014-0884-x
更新日期:2015-02-01 00:00:00
abstract::The authors report a rare case of imperforate anus as a congenital anomaly. Early diagnosis and close follow up are emphasized, in order to prevent the development of complications which may last for a lifetime. ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02549605
更新日期:1991-01-01 00:00:00
abstract:OBJECTIVE:To determine the prostate specific antigen (PSA) population standards of a cluster of Turkish men with no clinical evidence of prostate cancer. PATIENTS AND METHODS:We evaluated PSA values of the men who were living in a well-defined, rural district of Western Anatolia. Two hundred fifty-seven men agreed to ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-004-7976-y
更新日期:2005-01-01 00:00:00
abstract::The objective of this study was to evaluate the prognostic factors and role of nephrectomy in metastatic renal cell carcinoma. We reviewed 62 cases of metastatic renal cell carcinoma (RCC) at presentation to document the factors influencing the survival and to evaluate the role of nephrectomy. Sex and age of the patie...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02564853
更新日期:1998-01-01 00:00:00
abstract::A review of 71 cases of horseshoe kidney accounting for 0.12% of the total number of patients seen at the Department of Urology, Semmelweis University Medical School, Budapest, over 25 years is presented. The incidence of the abnormality has been found twice as high in males as in females. The proportion of surgical c...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02082128
更新日期:1978-01-01 00:00:00
abstract::Two cases of rarely observed granulomatous prostatitis are presented. Unspecific clinical symptoms and a close similarity in clinical course to prostatic adenoma or adenocarcinoma may be misleading and produce severe diagnostic difficulties even for an experienced urologist. Close cooperation with a pathomorphologist ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02084115
更新日期:1986-01-01 00:00:00
abstract::Fifty-eight patients with urate calculi and 31 patients with other (non-urate) calculi were examined for total-body potassium by means of a total-body counter. The patients with urate calculosis were found to differ significantly in their total-body K from patients with other calculi as well as from normal subjects. T...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02082228
更新日期:1979-01-01 00:00:00