Abstract:
AIMS:Erectile dysfunction (ED) is a major care problem worldwide. Tadalafil and sildenafil are the two most common phosphodiesterase 5 inhibitors used to treat ED. This systematic review and meta-analysis were conducted to directly compare tadalafil with sildenafil for the treatment of ED. METHODS:We designed a strategy for searching the PubMed, Embase, EBSCO, Web of Science and Cochrane library databases; the reference lists of the retrieved studies were also investigated. A literature review was performed to identify all published randomized or non-randomized controlled trials that compared tadalafil with sildenafil for the treatment of ED and to assess the quality of the studies. Two investigators independently and blindly screened the studies for inclusion. The meta-analysis was performed using RevMan 5.0. RESULTS:A total of 16 trials that compared tadalafil with sildenafil for the treatment of ED were included in the meta-analysis. In the meta-analysis, tadalafil and sildenafil appeared to have similar efficacies and overall adverse event rates. However, compared with sildenafil, tadalafil significantly improved psychological outcomes. Furthermore, the patients and their partners preferred tadalafil over sildenafil, and no significant difference was found in the adherence and persistence rates between tadalafil and sildenafil. Additionally, the myalgia and back pain rates were higher and the flushing rate was lower with tadalafil than with sildenafil. CONCLUSION:Tadalafil shares a similar efficacy and safety with sildenafil and significantly improves patients' sexual confidence. Furthermore, patients and their partners prefer tadalafil to sildenafil. Hence, tadalafil may be a better choice for ED treatment.
journal_name
Int Urol Nephroljournal_title
International urology and nephrologyauthors
Gong B,Ma M,Xie W,Yang X,Huang Y,Sun T,Luo Y,Huang Jdoi
10.1007/s11255-017-1644-5subject
Has Abstractpub_date
2017-10-01 00:00:00pages
1731-1740issue
10eissn
0301-1623issn
1573-2584pii
10.1007/s11255-017-1644-5journal_volume
49pub_type
杂志文章,meta分析,评审abstract:BACKGROUND:Cardiovascular disease is the most common cause of death in patients with chronic kidney disease (CKD). Epicardial adipose tissue (EAT) is an independent predictor of cardiovascular disease in the general population, and usually increases in the patients with cardiovascular disease risk. The change of EAT in...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-020-02575-y
更新日期:2020-12-01 00:00:00
abstract::Disorders in calcium, phosphorus, and parathyroid hormone (PTH) are common in chronic kidney disease (CKD) and may be associated with poor outcomes including a higher rate of CKD progression and increased death risk. Although these abnormalities have been examined extensively in patients with CKD stage 5 who are recei...
journal_title:International urology and nephrology
pub_type: 杂志文章,评审
doi:10.1007/s11255-008-9346-7
更新日期:2008-01-01 00:00:00
abstract::Renal inflammatory pseudotumor is a very rare benign condition of unknown etiology characterized by proliferative myofibroblasts, fibroblasts, histiocytes, and plasma cells. We report a case of inflammatory pseudotumor of the kidney. A 42-year-old female was admitted with the complaint of right flank pain. Computerize...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1023/b:urol.0000034661.52215.a3
更新日期:2004-01-01 00:00:00
abstract:OBJECTIVES:To prospectively compare biopsy outcomes between free-hand transperineal mpMRI/TRUS fusion targeted biopsy (TB) and transperineal systematic biopsy (SB) in patients with first prostate biopsy. PATIENTS AND METHODS:In all, 224 consecutive patients with the suspicion of PCa were investigated. All patients wer...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-016-1484-8
更新日期:2017-03-01 00:00:00
abstract::Using the materials of more than 200 scientific papers of recent years in this review it has been carried out analysis of the effectiveness and also discussed the merits and demerits of various methods of treatment of urinary stone diseases (USD). With this purpose, for the first time it has been carried out analysis ...
journal_title:International urology and nephrology
pub_type: 杂志文章,评审
doi:10.1023/a:1015282526252
更新日期:2001-01-01 00:00:00
abstract::Percutaneous nephrolithotomy provides an attractive alternative to the surgical removal of renal stones as it is associated with reduced patient morbidity and shortened hospital stay. The advantages of this procedure may, however, be overshadowed by complications like bleeding, extravasation of irrigant fluid and infe...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1023/b:urol.0000022937.22909.65
更新日期:2003-01-01 00:00:00
abstract:BACKGROUND:Prolonged cold ischemia time (CIT) has been associated with inferior graft survival in kidney transplantation (KT). The aim of this study was to evaluate the impact of prolonged CIT on short- and long-term outcomes and to determine the possible ways to optimize the use of these organs. METHODS:All kidney tr...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-012-0235-8
更新日期:2012-10-01 00:00:00
abstract::Seventy-one women suffering from recurrent cystitis were analysed. The patients were randomly distributed into two groups, in accordance with the treatment given. Forty-one were treated medically and thirty were subjected to internal urethrotomy with the Otis urethrotome and antimicrobial agents. The results of treatm...
journal_title:International urology and nephrology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/BF02217138
更新日期:1980-01-01 00:00:00
abstract::Administration of intravenous iron to supplement erythropoiesis stimulating agents (ESAs) has become a common practice in the management of anemia in patients with end-stage renal disease. Randomized clinical trials of anemia correction in this population have shown more adverse outcomes in CKD and ESRD patients assig...
journal_title:International urology and nephrology
pub_type: 杂志文章,评审
doi:10.1007/s11255-011-0028-5
更新日期:2012-04-01 00:00:00
abstract:PURPOSE:The aim of this study was to examine the usefulness of three GFR-estimating equations (eGFR) compared with measured GFR (mGFR) in potential living kidney donors. METHODS:We compared the performance of the MDRD, CKD-Epi and Cockcroft-Gault equations with mGFR measured using (51)Cr-EDTA in 508 consecutive potent...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-014-0859-y
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:Bladder neck contracture (BNC) following prostatectomy has been reported in 0.5-32% of cases. While the etiology of a BNC is unclear, several factors have been associated with this complication, including blood loss, devascularization of bladder neck tissue, poor mucosal apposition and urinary extravasation....
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-007-9239-1
更新日期:2008-01-01 00:00:00
abstract::The objective of this study was to evaluate the prognostic factors and role of nephrectomy in metastatic renal cell carcinoma. We reviewed 62 cases of metastatic renal cell carcinoma (RCC) at presentation to document the factors influencing the survival and to evaluate the role of nephrectomy. Sex and age of the patie...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02564853
更新日期:1998-01-01 00:00:00
abstract::We have documented the data of squamous metaplasia of the bladder in 14 patients who had undergone cystoscopies for different reasons. In two biopsies, there were marked keratinization and cellular atypia. One of these two subjects was diagnosed as squamous carcinoma of the prostate and transitional cell carcinoma of ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1023/a:1007107110222
更新日期:1999-01-01 00:00:00
abstract:BACKGROUND:In the last decade, despite constant investigation, no current single treatment has been able to decrease the incidence of diabetic nephropathy and to significantly reduce progression of diabetic CKD. METHODS:Patients with type 2 diabetes mellitus and proteinuria (>0.5 g/day) after a screening and treatment...
journal_title:International urology and nephrology
pub_type: 杂志文章,随机对照试验
doi:10.1007/s11255-017-1697-5
更新日期:2017-12-01 00:00:00
abstract::Evaluation of potential candidates for testosterone replacement therapy (TRT) includes a complete medical history, physical examination, and hormonal screening. The choice of testosterone assay is important in clinical decision making. TRT should, in theory, approximate natural endogenous production of the hormone. Th...
journal_title:International urology and nephrology
pub_type: 杂志文章,评审
doi:10.1007/s11255-010-9879-4
更新日期:2012-02-01 00:00:00
abstract::Insulin resistance is characterized by the systemic impairment of insulin action and is usually the result of aging, obesity, chronic inflammation, or another factor that may contribute to the inhibition of the insulin signaling pathway. Insulin resistance is accompanied by defects in lipid metabolism and blood coagul...
journal_title:International urology and nephrology
pub_type: 杂志文章,评审
doi:10.1007/s11255-007-9244-4
更新日期:2008-01-01 00:00:00
abstract:INTRODUCTION:Factors responsible for the low incidence of clinical prostate cancer (3-8/100,000 men/year) in the Arab population remain unclear, but may be related to changes in steroid hormone metabolism. We compared the levels of serum conjugated and unconjugated steroids between Arab and Caucasian populations, to de...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-005-3619-1
更新日期:2006-01-01 00:00:00
abstract::Although brucellosis is an endemic disease in Mediterranean countries, there are few reported cases of Brucella endocarditis and glomerulonephritis. We report a case of Brucella prosthetic mitral valve endocarditis and glomerulonephritis that could be managed by using only antibiotic therapy, including rifampicin, dox...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-010-9895-4
更新日期:2012-04-01 00:00:00
abstract::The authors describe various possibilities of using uretero-ureterostomy in cases of healthy bladder an in cases of supracystic urinary diversion. The history and the technique of the operation are described. Attention is called to the direction of anastomosis in cases of ureters differing in the width of their lumen....
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02082423
更新日期:1981-01-01 00:00:00
abstract:OBJECTIVE:Questionnaires for adequate assessment of the urinary function of neurological patients are not available in Portuguese. The Qualiveen, developed in France for evaluation of general and urinary-related impact on QoL, has been successfully used in neurological patients. AIM:To translate the Qualiveen, to adap...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-008-9402-3
更新日期:2009-01-01 00:00:00
abstract:OBJECTIVE:Evaluation of ultrasonographic abnormalities with active Schistosoma haematobium infection in Yemeni patients. METHODS:As part of a cooperation between a private hospital and Schistosomiasis Control Project in Yemen, laboratory and ultrasonographic examinations were performed in 158 patients (8 females, 150 ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1023/a:1007168507070
更新日期:1999-01-01 00:00:00
abstract::Forty-two young men with abacterial prostatitis underwent physical examination, semen analyses, rectal US (TRUS) and magnetic resonance imaging (MRI) of the pelvis. Findings on TRUS showed no distinct differences like capsular irregularity, dilatation of the seminal vesicles and calcified foci in the prostate. In MRI ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02550227
更新日期:1998-01-01 00:00:00
abstract:OBJECTIVES:Uroepithelium repair has always been the subject of discussion in urology surgeries. Using human amniotic membrane allograft has already proved to be useful in other fields. In this study, we use amniotic membrane to repair uroepithelium injuries in rabbits. METHODS:Twenty healthy rabbits underwent surgery ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-009-9532-2
更新日期:2009-12-01 00:00:00
abstract::The authors present a series of 2,173 patients with renal tuberculosis seen between 1950 and 1979. This is group 1, serving only to show the incidence of renal tuberculosis during the antibiotic era. The fact is that the incidence of renal tuberculosis is going down slightly but constantly in the last years because th...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02082596
更新日期:1986-01-01 00:00:00
abstract::Serum, corpuscular and renal tissue phosphate (Pi) concentrations in normal and chronic renal failure rats were examined. A significant correlation was found between Pi levels and indications of renal function. In addition, there were significant relationships between phosphate levels and RBC, Hb, Hct, serum Fe, serum...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:
更新日期:1993-01-01 00:00:00
abstract::Tubular reabsorption of magnesium ( TRMg ) was calculated from the values of plasma ultrafiltrable Mg and urinary Mg in 36 patients with transplanted kidneys. The study revealed a defect in TRMg in all investigated patients. The lowest TRMg values were found in patients with poor function of the transplanted kidneys. ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02082706
更新日期:1984-01-01 00:00:00
abstract:AIMS:Sacral neurostimulation (SNS) involves a two-stage procedure to assess outcomes prior to permanent implantation. Stage 1 involves placement of a sacral lead that is externalized and tested for 2 weeks. Stage 2 is the implantation of a pulse generator in responders (≥ 50% improved). This study's purpose was to dete...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-011-9919-8
更新日期:2011-12-01 00:00:00
abstract::Sleep disorders for patients on dialysis are significant causes of a poorer quality of life and increased morbidity and mortality. No study has evaluated patients undergoing automated peritoneal dialysis (APD) to assess their sleep disorders compared to hemodialysis (HD) and continuous ambulatory peritoneal dialysis (...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-014-0860-5
更新日期:2015-02-01 00:00:00
abstract::An analysis of the ultrastructural features of 35 canine kidneys after hypothermic preservation in Rheomacrodex, Collins3 and Sacks II solutions, and subsequent autologous reperfusion for 2 to 3 hours is presented. Signs of irreversibility (intramitochondrial crista fragmentation, cell membrane rupture, detachment of ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02089353
更新日期:1980-01-01 00:00:00
abstract:OBJECTIVE:We aimed to investigate significance of smoking regarding pathologic and biochemical outcomes following radical prostatectomy (RP). MATERIALS AND METHODS:We reviewed data of 1,165 patients who underwent RP without any neoadjuvant or adjuvant therapy at our institution. Patients were categorized into two grou...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-011-9964-3
更新日期:2012-02-01 00:00:00