Abstract:
:Insulin resistance is characterized by the systemic impairment of insulin action and is usually the result of aging, obesity, chronic inflammation, or another factor that may contribute to the inhibition of the insulin signaling pathway. Insulin resistance is accompanied by defects in lipid metabolism and blood coagulation, hypertension, obesity, and vascular inflammation in a syndrome called syndrome X or metabolic syndrome. Metabolic syndrome is involved in the development of atherosclerosis with consequent cardiovascular complications including acute myocardial infarction, stroke, and vascular disease. Recent data have shown that vitamin D acts as a negative regulator of the renin gene and that vitamin D deficiency is followed by increased renin-angiotensin II expression. The link between the insulin signaling pathway/insulin resistance and the renin-angiotensin system has been well documented in previous studies. The present review focuses on disorders characterized by a reduction in vitamin D concentration or its receptor function and the development of insulin resistance or metabolic syndrome, and discusses also possible therapeutic interventions.
journal_name
Int Urol Nephroljournal_title
International urology and nephrologyauthors
Rammos G,Tseke P,Ziakka Sdoi
10.1007/s11255-007-9244-4subject
Has Abstractpub_date
2008-01-01 00:00:00pages
419-26issue
2eissn
0301-1623issn
1573-2584journal_volume
40pub_type
杂志文章,评审abstract::Children with nephrotic syndrome (NS) are at risk for sinovenous and arterial thrombosis, uncommon but serious complications of the nephrotic syndrome. Multiple factors are involved in the hypercoagulable state of patients with NS, for instance, enhanced platelet reactivity and deficiency of antithrombin III due to ur...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-008-9434-8
更新日期:2009-01-01 00:00:00
abstract::In a retrospective study of patients treated for germ cell tumours, the authors found seven patients with primary extragonadal tumours in the retroperitoneum. These tumours are, in terms of histology, identical with germ cell tumours of the testis. The disease manifests itself by pain in the kidney region, palpable ab...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02549572
更新日期:1988-01-01 00:00:00
abstract::The clinical course of 30 patients with idiopathic membranous glomerulonephritis has been followed up for 8.1 +/- 3.4 (4-17) years. First, in each case a long-term prednisone treatment was administered. During this therapy 12 (40%) patients improved and 9 had remission. In the 18 (60%) steroid resistant cases the trea...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02549523
更新日期:1988-01-01 00:00:00
abstract:PURPOSE:No safe ultrasound (US) parameters have been established to differentiate the causes of graft dysfunction. OBJECTIVES:To define US parameters and identify the predictors of normal graft evolution, delayed graft function (DGF), and rejection at the early period after kidney transplantation. METHODS:Between Jun...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-014-0896-6
更新日期:2015-02-01 00:00:00
abstract:INTRODUCTION:Factors responsible for the low incidence of clinical prostate cancer (3-8/100,000 men/year) in the Arab population remain unclear, but may be related to changes in steroid hormone metabolism. We compared the levels of serum conjugated and unconjugated steroids between Arab and Caucasian populations, to de...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-005-3619-1
更新日期:2006-01-01 00:00:00
abstract::Orthostatic hypotension is very common in the elderly. It increases morbidity and is an independant predictor of all cause mortality. It is defined as a fall in systolic blood pressure greater than 20 mm Hg or a fall in diastolic blood pressure greater than 10 mm Hg within 3 minutes of standing. Symptoms include light...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-005-7663-7
更新日期:2005-01-01 00:00:00
abstract::Serum, corpuscular and renal tissue phosphate (Pi) concentrations in normal and chronic renal failure rats were examined. A significant correlation was found between Pi levels and indications of renal function. In addition, there were significant relationships between phosphate levels and RBC, Hb, Hct, serum Fe, serum...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:
更新日期:1993-01-01 00:00:00
abstract::Primary squamous cell carcinoma of seminal vesicle is extremely rare, and most cases regarding seminal vesicle tumors failed to address this kind of tumor. A 54-year-old male patient presented with intermittent painless visual hematuria for 6 months was hospitalized. Ultrasonography, computerized tomography and magnet...
journal_title:International urology and nephrology
pub_type: 杂志文章,评审
doi:10.1007/s11255-012-0373-z
更新日期:2013-02-01 00:00:00
abstract:PURPOSE:Reusable flexible-ureteroscopes (fURS) require personnel and budget for processing and repairing, whereas single-use fURS were recently developed. After exclusive reusable fURS since 2011, we experienced high repair costs and single-use fURS were therefore introduced in mid-2017. We aimed to evaluate economic a...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-019-02230-1
更新日期:2019-10-01 00:00:00
abstract:OBJECTIVE:To investigate the association of retrocaval ureter with other congenital abnormalities. METHODS AND PATIENTS:Two new cases of retrocaval ureter are discussed and a detailed electronic search of the literature was mainly focused on the concomitant abnormalities. The first of our patients had also a glandular...
journal_title:International urology and nephrology
pub_type: 杂志文章,评审
doi:10.1023/a:1014436432109
更新日期:2002-01-01 00:00:00
abstract:OBJECTIVE:We aimed to investigate significance of smoking regarding pathologic and biochemical outcomes following radical prostatectomy (RP). MATERIALS AND METHODS:We reviewed data of 1,165 patients who underwent RP without any neoadjuvant or adjuvant therapy at our institution. Patients were categorized into two grou...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-011-9964-3
更新日期:2012-02-01 00:00:00
abstract::We report an unusual case of benign recurrent pheochromocytoma that developed at the same site 8 years following initial treatment. This tumor was managed successfully through the 11th rib bed using the transperitoneal extrapleural approach. ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1023/a:1021309023695
更新日期:2002-01-01 00:00:00
abstract::Biomedical informatics in Health (BIH) is the discipline in charge of capturing, handling and using information in health and biomedicine in order to improve the processes involved with assistance and management. Informatic nephrology has appeared as a product of the combination between conventional nephrology with BI...
journal_title:International urology and nephrology
pub_type: 杂志文章,评审
doi:10.1007/s11255-012-0282-1
更新日期:2013-08-01 00:00:00
abstract::One hundred patients with recurrent calcium nephrolithiasis were submitted to the Pak test. At fasting state hypercalciuria was found in 27 cases, while a group of 16 further patients became hypercalciuric after oral calcium load. Only measurement of urinary cAMP excretion in both conditions made it possible to diagno...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02083499
更新日期:1985-01-01 00:00:00
abstract:PURPOSE:To evaluate the usage of unidirectional barbed suture and its related implications in various surgeon-controlled robotic reconstructive urologic surgeries. METHODS:From March 2010 to March 2011, all patients undergoing various surgeon-controlled robotic reconstructive urologic surgeries utilizing barbed suture...
journal_title:International urology and nephrology
pub_type: 杂志文章,评审
doi:10.1007/s11255-011-0075-y
更新日期:2012-06-01 00:00:00
abstract:PURPOSE:To investigate the role of urinary neutrophil gelatinase-induced lipocalin (uNGAL) measurement in the early diagnosis of acute kidney injury that may occur after intraoperative ischemia in patients undergoing partial nephrectomy (PN). METHODS:This prospective study included 86 patients who underwent open lapar...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-020-02660-2
更新日期:2020-09-26 00:00:00
abstract:OBJECTIVE:To evaluate the clinical value of detected prostate-specific antigen (PSA) mRNA expression levels in circulating cells in patients with prostate cancer by quantitative real-time polymerase chain reaction (qRT-PCR) and to determine the effect of surgical manipulation on hematogenous dissemination. METHODS:Blo...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-008-9416-x
更新日期:2009-01-01 00:00:00
abstract:PURPOSE:To suggest a different method for diagnosing vesicoureteral reflux (VUR) in lieu of voiding cystourethrography (VCU), in order to prevent radiation exposure. MATERIALS AND METHODS:Fifty-two ureterorenal units of 26 patients were evaluated ultrasonographically for visualizing the renal collecting systems, both ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02550307
更新日期:1998-01-01 00:00:00
abstract:PURPOSE:Studies have shown the increased incidence of urinary tract cancers which are associated with a decrease in glomerular filtration rate (GFR). We hypothesized that patients with GFR < 60 ml/min/1.73 m2 have an increased risk for higher staging and histology grades of cancers and, therefore, the increased risk fo...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-019-02216-z
更新日期:2019-09-01 00:00:00
abstract::Intraglomerular embolization by tubular epithelial cell is a rare artefact found in needle biopsy specimens. The authors have observed this phenomenon in five out of 300 renal biopsy cases. Tubular epithelial cells, were present in the glomerular capillaries (in two cases) or in the capillaries and within the glomerul...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02559622
更新日期:1989-01-01 00:00:00
abstract::Twenty-six boys were evaluated and treated for posterior urethral valves. At the time the valves were diagnosed unilateral or bilateral vesicoureteral reflux was present in 58% of the ureters and 69% of the children, while dilatation of the upper urinary tract was present in 88% and 92%, respectively. There was a vari...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02549902
更新日期:1989-01-01 00:00:00
abstract::When a transfusion of packed red blood cells is given, the net potassium load results from lysis of some cells and absorption of potassium by surviving cells. Potassium load was calculated which results from administration of 1 unit (200 cc.) of packed RBC and also that resulting from administration of sufficient pack...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02082677
更新日期:1975-01-01 00:00:00
abstract::A case of spontaneous right uretero-cutaneous fistula complicated by spontaneous rupture of the urinary bladder is presented. This morbid state is extremely rare and has not been previously reported to the best of our knowledge. ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02564762
更新日期:1995-01-01 00:00:00
abstract::In this study we explored the possible role of arachidonoylethanolamine (AEA) in regulating blood pressure in patients on continuous ambulatory peritoneal dialysis (CAPD). One hundred and five patients on CAPD were enrolled. Volume status was evaluated by the overhydration (OH) value obtained by bioimpedance analysis....
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-012-0153-9
更新日期:2012-12-01 00:00:00
abstract::Renal osteodystrophy, a frequent complication of chronic renal failure, is usually assessed by periodic X-rays of bone which are both poorly reproducible and expensive. Seeking a better screening test for osteodystrophy, we evaluated the usefulness of serum alkaline phosphatase as a predictor of bone disease and of hy...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02085384
更新日期:1980-01-01 00:00:00
abstract::Megaureter and ureteropelvic junction obstruction are not uncommon urinary tract congenital abnormalities. While each has been known to be associated with other urogenital anomalies, their association together is rarely reported. This report will describe the diagnosis and management of such a case. ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02083010
更新日期:1983-01-01 00:00:00
abstract::The first time in Scandinavia we present a case report of a pure primary low-grade neuroendocrine carcinoma (carcinoid tumor) of the prostate. Our patient is a 34-year-old male with a long history of symptomatic chronic prostatitis/prostatodynia. After developing severe obstructive uropathy, a transurethral resection ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-009-9660-8
更新日期:2010-09-01 00:00:00
abstract:PURPOSE:The impact of radical surgery for urothelial carcinoma is significant on patient's quality of life. Organ-sparing surgery (OSS) can provide comparable oncological outcomes and with improved quality of life. In this review, we summarize the indications, techniques and outcomes of OSS for these tumors. METHODS:P...
journal_title:International urology and nephrology
pub_type: 杂志文章,评审
doi:10.1007/s11255-019-02232-z
更新日期:2019-11-01 00:00:00
abstract:PURPOSE:This study examined whether the laser-capture microdissection (LCM) method can achieve separation of urothelial cells from detrusor cells or superficial urothelial cells from intermediate/basal urothelial cells, using α-smooth muscle actin (SMA) and cytokeratin 20 (CK20). In addition, we investigated the change...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-015-0926-z
更新日期:2015-04-01 00:00:00
abstract::The authors report the late results of reconstructive surgery on stenosis of the pelvo-ureteral junction in children. 69 patients had been operated during 1965--1970. The results on clinical grounds were good: the infections and pain disappeared and the renal function was normal; however, the operation had no noticeab...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02085428
更新日期:1975-01-01 00:00:00