Abstract:
PURPOSE:The aim of this study was to examine the usefulness of three GFR-estimating equations (eGFR) compared with measured GFR (mGFR) in potential living kidney donors. METHODS:We compared the performance of the MDRD, CKD-Epi and Cockcroft-Gault equations with mGFR measured using (51)Cr-EDTA in 508 consecutive potential living kidney donors. Each equation was assessed for bias, precision and accuracy compared with mGFR, and the sensitivity and specificity for the identification of donors with mGFR<80 mL/min/1.73 m2 was evaluated. RESULTS:Two hundred and forty-four subjects were male, 398 Caucasian, 60 Afro-Caribbean and 50 from other ethnic groups. Median age and mGFR were 44.1 year and 91.7 mL/min/1.73 m2, respectively. Spearman correlation coefficients between eGFR and mGFR were in the range R s=0.520-0.593. Median bias (eGFR-mGFR) for the MDRD, CKD-Epi and Cockcroft-Gault equations were -1.0 (p=0.98), +8.8 (p<0.0001) and +11.1 (p<0.0001) mL/min/1.73 m2, respectively. Significant differences in bias between Afro-Caribbean and Caucasian subjects were found. The sensitivity (specificity) for the MDRD, CKD-Epi and Cockcroft-Gault equations for identifying subjects with mGFR<80 mL/min/1.73 m2 was 60 (83), 39 (95) and 44% (95%), respectively. CONCLUSIONS:The level of agreement between mGFR and all three eGFR values was poor, with the MDRD equation performing best. We conclude that reliance on creatinine-based eGFR values is unsatisfactory for the evaluation of potential living kidney donors.
journal_name
Int Urol Nephroljournal_title
International urology and nephrologyauthors
Bhuvanakrishna T,Blake GM,Hilton R,Burnapp L,Sibley-Allen C,Goldsmith Ddoi
10.1007/s11255-014-0859-ysubject
Has Abstractpub_date
2015-01-01 00:00:00pages
201-8issue
1eissn
0301-1623issn
1573-2584journal_volume
47pub_type
杂志文章abstract::Low-molecular-weight heparins (LMWHs) have been widely used in many clinical settings. LMWH-associated spontaneous retroperitoneal hematoma (SRH) has been reported mostly in patients treated with enoxaparin. We here present a 76-year-old man with renal insufficiency treated with dalteparin for acute myocardial infarct...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-011-0104-x
更新日期:2012-08-01 00:00:00
abstract:OBJECTIVE:Chronic hepatitis B virus (HBV) carrier status has a critical impact on clinical management of patients with IgA nephropathy (IgAN) who are treated with corticosteroids, because corticosteroids may enhance HBV replication. This study compared corticosteroids and antivirals combined therapy with corticosteroid...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-013-0480-5
更新日期:2014-01-01 00:00:00
abstract:OBJECTIVES:Metformin has been shown to reduce diabetic complications in overweight patients, and is increasingly used to treat this condition. However, this agent is associated with a rare but serious risk of lactic acidosis. METHODS:From January 2004 to November 2008, 11 cases of metformin-associated lactic acidosis ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-009-9549-6
更新日期:2009-12-01 00:00:00
abstract::Experience in the treatment of urinary bladder cancer based upon observation of 306 cases has been presented. Two hundred and thirteen patients were treated surgically by performing in 151 cases partial cystectomy and in 62 cases total cystectomy. Conservative treatment was applied in 75 patients. In the authors' opin...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02082168
更新日期:1977-01-01 00:00:00
abstract:BACKGROUND:It has been shown that residual renal function but not peritoneal clearance predicted patients' survival in peritoneal dialysis therapy. In the present study, we tried to explore the potential causes resulting in the difference between residual renal function and peritoneal dialysis in continuous ambulatory ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-005-4011-x
更新日期:2005-01-01 00:00:00
abstract::Five characteristics of neonate renal physiology, namely glomerular hypofiltration, low renal blood flow and alterations in water, sodium and potassium management, disappear during the first year of life but reoccur during senescence. However, the underlying mechanisms are different during the two periods. ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1023/b:urol.0000034681.60457.84
更新日期:2004-01-01 00:00:00
abstract:BACKGROUND:ADPKD is one of the most common inherited disorders, with high risk for end-stage renal disease. Numerous patients, however, have no relatives in whom this disorder is known and are unsure whether they may transmit the disease to their offsprings. The aim of this study was to evaluate whether germline mutati...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-012-0125-0
更新日期:2012-12-01 00:00:00
abstract::Leptospirosis is an infectious disease caused by pathogenic leptospires and is characterized by a broad spectrum of clinical manifestations, varying from inappearent infection to fulminant, fetal disease. Eighty-five to 90% of leptospirosis infections are self-limiting. However, 5-10% of infection by L. interrogans ca...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1023/a:1014494012062
更新日期:2002-01-01 00:00:00
abstract::The aim of this study was to find out whether an improvement of vitamin D metabolism and its metabolites and a decrease of parathormones can be reached through a diet and UV irradiation. Forty-eight children with kidney insufficiency were divided into four groups: Group 1--diet according to Bergström with EAA and ceto...
journal_title:International urology and nephrology
pub_type: 临床试验,杂志文章
doi:
更新日期:1993-01-01 00:00:00
abstract:PURPOSE:The age-related decline of the testosterone-to-estrogen (T-to-E2) ratio in serum is associated with the increased prevalence of prostatic inflammation. The goal of the study was to induce prostatic inflammation with E2 and androgen treatment and to explore the inflammatory markers and apoptosis on prostatitis. ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-014-0845-4
更新日期:2015-01-01 00:00:00
abstract:AIM:Chronic prostatitis (CP) and chronic pelvic pain syndrome (CPPS) is a common disabling condition that is primarily associated with pain in the urogenital region and disturbances in urinary and sexual function. Chronic pelvic pain symptoms are the most common presentation, especially perineal, lower abdominal, testi...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-010-9809-5
更新日期:2011-06-01 00:00:00
abstract:OBJECTIVE/BACKGROUND:The aim of this study was to evaluate the efficacy of the autologous fascia rectus sling in treating stress urinary incontinence in female patients with neuropathic bladder. Furthermore, correlations between preoperative parameters and outcome were evaluated. METHODS AND DESIGN:We retrospectively ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-012-0247-4
更新日期:2012-10-01 00:00:00
abstract:PURPOSE:Chronic kidney disease (CKD) is associated with a high incidence of obstructive sleep apnea (OSA). We assessed the effect of continuous positive airway pressure (CPAP) on renal function in patients with CKD and OSA. METHODS:In this retrospective cohort study, 42 patients with Stage 3-5 CKD and OSA were stratif...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-015-1113-y
更新日期:2015-11-01 00:00:00
abstract:OBJECTIVES:To prospectively compare biopsy outcomes between free-hand transperineal mpMRI/TRUS fusion targeted biopsy (TB) and transperineal systematic biopsy (SB) in patients with first prostate biopsy. PATIENTS AND METHODS:In all, 224 consecutive patients with the suspicion of PCa were investigated. All patients wer...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-016-1484-8
更新日期:2017-03-01 00:00:00
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journal_title:International urology and nephrology
pub_type: 杂志文章
doi:
更新日期:1993-01-01 00:00:00
abstract:OBJECTIVE:Supracostal superior calyceal access has been shown to be the most suitable approach for staghorn calculi, calculi in the upper ureter, and complex inferior calyceal calculi. It is a good choice for direct access for most of the intrarenal collecting system and upper ureter. The aim of this retrospective stud...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-011-9916-y
更新日期:2011-12-01 00:00:00
abstract:PURPOSE:To compare multiparametric magnetic resonance imaging (mpMRI) with transrectal ultrasound-guided prostate biopsy (TRUS-bx) for the diagnosis and monitoring of small-volume prostate cancer (PCa) in patients on active surveillance (AS). METHODS:In a retrospective cross-sectional validation study, 100 patients on...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-016-1212-4
更新日期:2016-04-01 00:00:00
abstract:BACKGROUND:HAAKI is a common clinical problem in hospitalized patients. Its incidence is high in older patients and carries worse prognosis. The presence of multiple co-morbidities, aging process, and frequent diagnostic and therapeutic interventions predispose elderly patients to HAAKI. This study aims to evaluate the...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-019-02130-4
更新日期:2019-05-01 00:00:00
abstract:UNLABELLED:End-to-end of terminal ureteral segments seems to be a good alternative to terminal cutaneous ureterostomy in very selected cases (patients with short life-expectancy or when it is impossible to utilize the bowel for urinary diversion). BACKGROUND:An end-to-end ureteral anastomosis (UA) drained by a single ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-004-7971-3
更新日期:2005-01-01 00:00:00
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journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02082674
更新日期:1975-01-01 00:00:00
abstract::Non-refluxing non-obstructive megaureter is a rare condition, usually diagnosed in asymptomatic neonates. We present the case of a 39-year-old male, who presented with a 6-month history of recurrent UTIs and intermittent frank haematuria. IVU, flexible cystoscopy and micturating cystogram confirmed characteristically ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-006-9054-0
更新日期:2007-01-01 00:00:00
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doi:10.1007/s11255-012-0266-1
更新日期:2012-12-01 00:00:00
abstract::Behcet's disease (BD) is a rare chronic, relapsing, multisystemic disorder characterized by mucocutaneous, ocular, vascular and central nervous system manifestations. However, the etiopathogenesis of the disease remains unknown, and diagnosis is basically dependent on clinical manifestations. Sometimes BD may be diagn...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-013-0519-7
更新日期:2014-02-01 00:00:00
abstract:PURPOSE:Timely risk assessment of chronic kidney disease (CKD) and proper community-based CKD monitoring are important to prevent patients with potential risk from further kidney injuries. As many symptoms are associated with the progressive development of CKD, evaluating risk of CKD through a set of clinical data of s...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-016-1346-4
更新日期:2016-12-01 00:00:00
abstract:PURPOSE:To compare efficacy, safety, and cost-effectiveness of fosfomycin tromethamine with other standard-of-care antibiotics in patients undergoing ureteroscopic lithotripsy. METHODS:This study was a prospective, multicenter, randomized, controlled trial. Eligible patients scheduled for ureteroscopic lithotripsy wer...
journal_title:International urology and nephrology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1007/s11255-017-1776-7
更新日期:2018-03-01 00:00:00
abstract:PURPOSE:To perform a systematic review and meta-analysis to evaluate the cardiovascular prevention effect of aspirin among patients with chronic kidney disease (CKD). METHODS:A comprehensive literature search was conducted in Embase, PubMed, and Cochrane library (up to March 2019) without language limitations. Randomi...
journal_title:International urology and nephrology
pub_type: 杂志文章,meta分析
doi:10.1007/s11255-019-02350-8
更新日期:2020-02-01 00:00:00
abstract:BACKGROUND:The use of anabolic steroids and vitamin supplements has reached alarming proportions in the last decades. Adverse effects have been documented and include virilization, feminization, adverse lipid profile, psychiatric disorders, cardiac and liver disease. Acute kidney injury (AKI) is not frequently describe...
journal_title:International urology and nephrology
pub_type: 杂志文章,评审
doi:10.1007/s11255-009-9571-8
更新日期:2009-01-01 00:00:00
abstract::To compare the anti-inflammatory effectiveness of corticotherapy and nonsteroid anti-inflammatory drugs (NSAID), we examined 126 infertile men with infectious aetiology. Seventy-seven patients were on corticotherapy and antibiotherapy (thirty-eight patients on high-dose and thirty-nine patients on low-dose corticother...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1023/a:1007184125900
更新日期:1999-01-01 00:00:00
abstract:PURPOSE:This present study aims to investigate the relationship between laboratory parameters on admission and prognosis of coronavirus disease 2019 (COVID-19) in maintenance hemodialysis patients, as well as providing a theoretical basis for clinical evaluation of prognosis and corresponding intervention measures. ME...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-020-02646-0
更新日期:2021-01-01 00:00:00
abstract:PURPOSE:Our aim was to compare the different characteristics and outcomes of the Amplatz sheaths and single-step metallic dilators which were used for mini-PCNL procedure in a single institution. METHODS:Retrospective medical records of 236 patients who underwent mini-PCNL were reviewed and divided into Amplatz (n = 1...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-017-1516-z
更新日期:2017-04-01 00:00:00