Abstract：
PURPOSE:Varicocele is among the leading causes of male infertility. Despite decades of research, its pathogenesis is still unclear. S100A12 is a member of the S100 family of calcium-binding proteins with principal extracellular activities. It is secreted by activated neutrophils and interacts with the multiligand receptor for advanced glycation end products (RAGE). Many studies have delineated the patterns of S100A12 expression in a variety of pathologic conditions. These data show that S100A12 could be a potentially useful inflammatory marker. To explore the relationship between S100A12 and infertility, we examined the amount of S100A12 in semen of infertile men who suffered from varicocele. METHODS:S100A12 levels in seminal plasma of 68 infertile men with varicocele (age range 30-45 years) and 68 healthy fertile controls were measured using ELISA. Statistical analysis was performed using both parametric and nonparametric tests. RESULTS:Results of this study showed that the seminal levels of S100A12 were significantly increased in infertile men with varicocele when compared to fertile controls (P < 0.001). CONCLUSIONS:Because of the important role(s) of these molecules in inflammatory response of cell systems, it could be possible that the spermatozoa motility is reduced following increasing neutrophils, S100A12, and reactive oxygen species in semen of infertile patients with varicocele. S100 proteins seem to be potential biomarkers and therapeutic targets for male infertility.
journal_name
Int Urol Nephroljournal_title
International urology and nephrologyauthors
Bagheri V,Hassanshahi G,Zeinali M,Abedinzadeh M,Khorramdelazad Hdoi
10.1007/s11255-015-1188-5subject
Has Abstractpub_date
2016-03-01 00:00:00pages
343-7issue
3eissn
0301-1623issn
1573-2584pii
10.1007/s11255-015-1188-5journal_volume
48pub_type
杂志文章abstract：PURPOSE:Cardiovascular (CV) events are the first cause of death in patients with chronic renal disease (CKD) and in patients with type 2 diabetes mellitus (DM2). The combination of CKD and DM2 elevates the risk of both cardiovascular disease (CVD) and death in this high-risk population. Besides traditional risk factors...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/s11255-017-1755-z
更新日期：2018-02-01 00:00:00
abstract：:Recipients of renal allografts are surviving longer and, consequently, may experience a variety of complications related not only to the transplanted kidney, but also to the hematopoietic system. Common hematologic complications in the renal transplant patient include abnormalities of one cell line, such as post-trans...
journal_title：International urology and nephrology
pub_type： 杂志文章,评审
doi：10.1007/s11255-009-9558-5
更新日期：2010-03-01 00:00:00
abstract：:Ganglioneuroblastoma is a common type of tumor in children, but is rarely seen in adults. We present here a case of adrenal ganglioneuroblastoma in a 59-year old man. ...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/s11255-004-0851-z
更新日期：2004-01-01 00:00:00
abstract：OBJECTIVE:The present study investigated the inhibitory effects of a novel minimally invasive implanted tibial nerve stimulation device on non-nociceptive bladder reflexes in cats. MATERIALS AND METHODS:A wireless minimally invasive implanted nerve stimulator was implanted adjacent to the left tibial nerve in seven ca...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/s11255-020-02666-w
更新日期：2020-09-28 00:00:00
abstract：:The results of an investigation dealing with the therapy of instability of the detrusor using oxybutynin hydrochloride are presented. Out of an unselected group of patients 21 were enrolled in the trial. After therapy 19 patients showed significant improvement of subjective symptoms and objective urodynamic parameters...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/BF02550401
更新日期：1990-01-01 00:00:00
abstract：BACKGROUND:The adequate control of phosphataemia is of major importance in end-stage renal disease patients on maintenance dialysis. Recently, lanthanum carbonate (LC) has been added to the phosphate binder armamentarium. To our knowledge, no studies have yet evaluated the usefulness of this drug in uncontrolled hyperp...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/s11255-010-9860-2
更新日期：2012-02-01 00:00:00
abstract：OBJECTIVE:To report a case of a 31-year-old woman with renal angiomyolipoma (RAML) who presented with progressive massive haematuria with successive pregnancies. CLINICAL PRESENTATION:A 28-year-old woman presented with mild haematuria in the third trimester of her second pregnancy. This was due to bleeding from a left...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/s11255-006-9036-2
更新日期：2007-01-01 00:00:00
abstract：:We report the unusual case of a patient with G3 pT1 transitional cell carcinoma (TCC) of the bladder, which was treated with repeated transurethral resection and maintenance intravesical Bacillus Calmette-Guérin (BCG) therapy. At 30 months follow-up, a symptomatic, solitary iliac lymph node mass was identified and bio...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/s11255-007-9187-9
更新日期：2007-01-01 00:00:00
abstract：:Insulin resistance is characterized by the systemic impairment of insulin action and is usually the result of aging, obesity, chronic inflammation, or another factor that may contribute to the inhibition of the insulin signaling pathway. Insulin resistance is accompanied by defects in lipid metabolism and blood coagul...
journal_title：International urology and nephrology
pub_type： 杂志文章,评审
doi：10.1007/s11255-007-9244-4
更新日期：2008-01-01 00:00:00
abstract：PURPOSE:We sought to evaluate the effects of oral testosterone undecanoate treatment based on the temporary growth of penis and the complications of surgery in children with microphallic hypospadias. MATERIALS AND METHODS:A total of 72 randomized consecutive children with microphallic hypospadias were included in the ...
journal_title：International urology and nephrology
pub_type： 杂志文章,随机对照试验
doi：10.1007/s11255-015-0972-6
更新日期：2015-06-01 00:00:00
abstract：AIM:To investigate the correlation of renal tubular inflammatory and injury markers with renal uric acid excretion in chronic kidney disease (CKD) patients. METHODS:Seventy-three patients with CKD were enrolled. Fasting blood and morning urine sample were collected for routine laboratory measurements. At the same time...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/s11255-020-02447-5
更新日期：2020-05-01 00:00:00
abstract：:In this study, 31 (30%) cases of urinary tract infection (UTI) of 103 patients with malnutrition, who were admitted to our hospital, were investigated prospectively. Our purpose was to determine the frequency of UTI, species of bacteria caused to infection and their antibiotic susceptibility in infants with malnutriti...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1023/a:1007104326689
更新日期：2000-01-01 00:00:00
abstract：:A total of 234 patients with chronic glomerulonephritis, detected on the basis of clinical, immunological and pathomorphological criteria, have been examined. A group of 23 chronic glomerulonephritis patients with massive deposits of immunoglobulin A found by immunofluorescent examination, has been separated on the ba...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/BF02085414
更新日期：1985-01-01 00:00:00
abstract：BACKGROUND:Chronic kidney disease (CKD) is a worldwide health problem, and promotion of the World Kidney Day has improved general population education and awareness of renal illnesses aimed at ameliorating disease prevention. The Kidney Day was also an opportunity for us to investigate risk factors for CKD in an Italia...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/s11255-010-9861-1
更新日期：2011-09-01 00:00:00
abstract：:Five characteristics of neonate renal physiology, namely glomerular hypofiltration, low renal blood flow and alterations in water, sodium and potassium management, disappear during the first year of life but reoccur during senescence. However, the underlying mechanisms are different during the two periods. ...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1023/b:urol.0000034681.60457.84
更新日期：2004-01-01 00:00:00
abstract：:We report a case involving a 55-year-old healthy man that presented with urinary retention and a lower abdominal mass. His evaluation revealed a large mucocele arising from the appendix that caused severe bilateral ureteral obstruction and renal failure. Appendiceal mucoceles are rare and insidious entities that can p...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/s11255-005-0917-6
更新日期：2005-01-01 00:00:00
abstract：PURPOSE:Anaemia and resistance to erythropoiesis-stimulating agents (ESAs) are common complications in haemodialysis (HD) patients. We investigated the role of hepcidin in the development of anaemia and ESA resistance/hyporesponsiveness and its relation to the plasma levels of the inflammatory markers interleukin 6 (IL...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/s11255-018-2062-z
更新日期：2019-02-01 00:00:00
abstract：BACKGROUND:Chronic kidney disease (CKD) has been identified as a growing global burden and traditional health care systems are inadequate for the management of CKD patients. This paper describes an initiative to establish a renal management clinic (RMC) in China and discusses the challenges and opportunities in the man...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/s11255-008-9450-8
更新日期：2008-01-01 00:00:00
abstract：:We are presenting a 68-year-old female patient who was diagnosed to have a complete ureteral duplication and adenocarcinoma in the ureter which drained the upper moiety of the right kidney. ...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1023/b:urol.0000025627.15113.e3
更新日期：2003-01-01 00:00:00
abstract：PURPOSE:To analyse the incidence and management of emphysematous pyelonephritis (EPN) in North West London and examine factors that influence immediate and 6-month outcomes with the aim of guiding future management. METHODS:This work analyses EPN cases from the London North West Healthcare NHS Trust from October 2006 ...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/s11255-017-1706-8
更新日期：2017-12-01 00:00:00
abstract：:The effect of Ergobromocriptine treatment on serum testosterone and prolactin levels in 15 patients with prostatic carcinoma and 15 patients with benign prostatic hyperplasia was examined. The prolactin levels which were elevated in patients with prostatic carcinoma showed a significant decrease after suppression with...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/BF02082651
更新日期：1986-01-01 00:00:00
abstract：:Observations with diagnostic ultrasound in renal disease over a 10-year period are reviewed. The advantages of diagnostic methods involving the least possible discomfort to the patient are emphasized. Ultrasonography is regarded as a reliable non-invasive method for the diagnostic differentiation between renal tumours...
journal_title：International urology and nephrology
pub_type： 杂志文章,评审
doi：10.1007/BF02083009
更新日期：1983-01-01 00:00:00
abstract：:Artificial insemination (ADI) has been carried out with donor semen since 1984. Following artificial insemination 14 women out of 27 became pregnant in 1984, 30 women out of 57 in 1985 and 33 women out of 56 until October 1, 1986. The cycles were monitored. Serum LH and oestradiol levels were determined every day from...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/BF02549573
更新日期：1988-01-01 00:00:00
abstract：OBJECTIVE:Previous studies on the association between extracorporeal shock wave lithotripsy (SWL) and new onset hypertension have only illustrated contradictory results. In order to illustrate the association between SWL and new onset hypertension, a meta-analysis of case-control and cohort studies was conducted. METH...
journal_title：International urology and nephrology
pub_type： 杂志文章,meta分析,评审
doi：10.1007/s11255-013-0588-7
更新日期：2014-04-01 00:00:00
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journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/s11255-007-9278-7
更新日期：2008-01-01 00:00:00
abstract：OBJECTIVES:Surgical removal of completely endophytic renal tumors has presented great technical difficulties for surgeons. In this study, we aim to introduce the role and use of intraoperative ultrasound (IOUS) performed in robotic-assisted renal partial nephrectomy (RAPN) for endophytic renal tumors. METHODS:We retro...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/s11255-020-02664-y
更新日期：2020-10-01 00:00:00
abstract：PURPOSE:To compare efficacy, safety, and cost-effectiveness of fosfomycin tromethamine with other standard-of-care antibiotics in patients undergoing ureteroscopic lithotripsy. METHODS:This study was a prospective, multicenter, randomized, controlled trial. Eligible patients scheduled for ureteroscopic lithotripsy wer...
journal_title：International urology and nephrology
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1007/s11255-017-1776-7
更新日期：2018-03-01 00:00:00
abstract：PURPOSE:This study investigated the clinical characteristics and symptomatology of ESRD patients in Jordan taking a multidimensional approach. METHODS:This was a cross-sectional study that included a cohort of 620 patients undergoing maintenance hemodialysis (HD). Data were retrieved via patient survey administration ...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/s11255-020-02458-2
更新日期：2020-05-01 00:00:00
abstract：OBJECTIVES:To evaluate the results and complications in 170 patients with symptomatic benign hyperplasia who underwent laser prostatectomy focusing on six month and long-term results. METHODS:A total of 170 patients underwent side firing Neodymium:Yag laser prostatectomy between January 1995 and February 2001 of whom ...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1023/a:1025948028530
更新日期：2003-01-01 00:00:00
abstract：OBJECTIVES:PSA is regarded as the best method in the follow-up of prostate carcinoma. After radical vesiculo-prostatectomy the prostate carcinoma seldom recurs at zero or nearly zero PSA levels. METHODS:The authors have used PSA since 1989 and they have found only one case where metastasis in the tibia came without an...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1023/a:1007142910479
更新日期：2000-01-01 00:00:00
