Abstract：
:The best "treatment" of acute kidney injury (AKI) is prevention. Patients who are at high risk of AKI should have an assessment of their volume status and receive appropriate volume expansion. The most effective type of intravenous fluid remains unclear. Innumerable studies have compared sodium bicarbonate and isotonic saline and have combined fluid hydration with pharmacological interventions, particularly N-acetyl-cysteine. However, abundant systematic reviews and meta-analyses have provided conflicting conclusions and have recognized a significant degree of heterogeneity between studies and publication bias. Most studies comparing intravenous sodium bicarbonate and saline were small. They often enrolled patients with a low risk for AKI, yielding low serious events (renal replacement therapy), and used different protocols for administration of fluids. Based on current literature, intravenous sodium bicarbonate does not seem to be more efficient than saline for the prevention of contrast-media-induced AKI, cardiac surgery-associated AKI, pigment nephropathy or septic AKI. However, some cohort studies or prospective randomized trials did track and report serious adverse events, such as higher rates of AKI or higher in-hospital mortality. At present, it should be concluded that the use of intravenous sodium bicarbonate administration to prevent AKI should be evaluated further in multicenter randomized double-blind trials rather than adopted into routine clinical practice.
journal_name
Int Urol Nephroljournal_title
International urology and nephrologyauthors
Schiffl Hdoi
10.1007/s11255-014-0820-0subject
Has Abstractpub_date
2015-02-01 00:00:00pages
321-6issue
2eissn
0301-1623issn
1573-2584journal_volume
47pub_type
社论,评审abstract：PURPOSE:The purpose of this study was to evaluate the efficacy of tegafur-uracil (UFT) administration as a fourth-line therapy in patients with castration-resistant prostate cancer (CRPC) who had already received combined androgen blockade (CAB) therapy (first-line), alternative antiandrogen therapy (second-line), and ...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/s11255-013-0634-5
更新日期：2014-06-01 00:00:00
abstract：:The authors describe a case of ureteral fibroma. The aetiology, clinical symptomatology and diagnosis are discussed, and differentiation between benign and malignant lesions is emphasized. ...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/BF02552113
更新日期：1992-01-01 00:00:00
abstract：:In this study, we evaluated low dose intravesical bacillus Calmette-Guerin (BCG) therapy following transurethral resection (TUR) in 80 patients with superficial bladder cancer. The patients were divided into two groups. Of the Connaught BCG strain 81 mg was given to 40 patients in Group 1 and 54 mg to the remainder of...
journal_title：International urology and nephrology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1007/BF02550276
更新日期：1998-01-01 00:00:00
abstract：PURPOSE:Smoking habit is the major risk factor for bladder cancer (BC), related to about 50% of these tumors; however, the tobacco dose-effect impact on BC immune treatment is underexplored. This study evaluates the impact of smoke load on non-muscle invasive bladder cancer (NMIBC) prognosis after intravesical BCG. ME...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/s11255-020-02438-6
更新日期：2020-08-01 00:00:00
abstract：PURPOSE:Water intake is important for preventing kidney stones. Small molecules water is a more active restructured water under magnetic field. Here, we studied the relation between small molecules water and crystal formation in the rat kidney. MATERIALS:The small molecules water was prepared by a water machine provid...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/s11255-017-1769-6
更新日期：2018-02-01 00:00:00
abstract：OBJECTIVES:Uroepithelium repair has always been the subject of discussion in urology surgeries. Using human amniotic membrane allograft has already proved to be useful in other fields. In this study, we use amniotic membrane to repair uroepithelium injuries in rabbits. METHODS:Twenty healthy rabbits underwent surgery ...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/s11255-009-9532-2
更新日期：2009-12-01 00:00:00
abstract：:A study was carried out to verify the clinical usefulness of the elaborated method for the measurement of antistreptococcal antibody in revealing the streptococcal etiology of glomerulonephritis. In 158 patients with glomerulonephritis antistreptococcal antibody (ASA), circulating immune complexes (CIC) and haemolytic...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/BF02082387
更新日期：1982-01-01 00:00:00
abstract：OBJECTIVES:Surgical removal of completely endophytic renal tumors has presented great technical difficulties for surgeons. In this study, we aim to introduce the role and use of intraoperative ultrasound (IOUS) performed in robotic-assisted renal partial nephrectomy (RAPN) for endophytic renal tumors. METHODS:We retro...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/s11255-020-02664-y
更新日期：2020-10-01 00:00:00
abstract：:Ureteral endometriosis is a rare disease that typically is unilateral. Endometriosis involving both ureters and surgical management after hormone therapy failure has seldom been described. We describe a patient with bilateral ureteral endometriosis who underwent ureteroneocystostomy with psoas hitches of both ureters....
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/s11255-006-0101-7
更新日期：2006-01-01 00:00:00
abstract：:Megaureter and ureteropelvic junction obstruction are not uncommon urinary tract congenital abnormalities. While each has been known to be associated with other urogenital anomalies, their association together is rarely reported. This report will describe the diagnosis and management of such a case. ...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/BF02083010
更新日期：1983-01-01 00:00:00
abstract：:A modified method of retropubic radical prostatectomy was devised. The root of the penis was compressed and the bilateral internal iliac arteries were clamped before the dissection of the prostate. The urethra was divided at the junction of the prostate and bladder so that the bladder stump thus created has the size o...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/BF02549537
更新日期：1992-01-01 00:00:00
abstract：:The white blood cell count (WBC) decreases during haemodialysis and it was investigated as a function of different dialysis membranes. Each of them was used four times, applying different sterilization methods. Twelve chronic haemodialysis patients were studied and dialysed with cuprophan and polyacrylonitrile (PAN) m...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/BF02082704
更新日期：1984-01-01 00:00:00
abstract：:In recent years, the role of trace elements in lithogenesis has received steadily increasing attention. It is well documented that some trace elements can influence the morphology and speed of the crystallization process. Zinc has been found in significant amounts in calcium stones relative or organic stones (uric aci...
journal_title：International urology and nephrology
pub_type： 杂志文章,评审
doi：10.1007/s11255-017-1784-7
更新日期：2018-05-01 00:00:00
abstract：BACKGROUND:Recently, great progress has been made in understanding the pathogenesis of membranous nephropathy (MN) with the discovery of autoantibodies (Abs) to M-type phospholipase A2 receptor (PLA2R) in serum and in immunocomplexes deposited in glomerulus in most adult patients with primary MN. OBJECTIVE:To evaluate...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/s11255-020-02682-w
更新日期：2020-10-31 00:00:00
abstract：PURPOSE:Chronic kidney disease (CKD) is an inflammatory process. In addition to increased morbidity and mortality, inflammation also contributes to the progression of CKD. Neutrophil/lymphocyte ratio (NLR) is a marker of inflammation. Some recent data suggest that NLR may predict the progression of CKD. METHODS:In thi...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/s11255-018-1994-7
更新日期：2019-01-01 00:00:00
abstract：:A total of 42 neurologically normal children with different voiding problems have been studied urodynamically during the last 4 years. Seventeen patients had unstable bladder, with significantly decreased capacity. The degree of volume decrease depended on the severity of instability and on the type of micturition pro...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：
更新日期：1993-01-01 00:00:00
abstract：:We report on our experience with a new surgical procedure of forming a pseudoneotesticle from indigenous tissues obtained from the existing scrotal contents. This procedure has been performed in 32 patients with a diagnosis of hormone dependent cancer of the prostate as a therapeutic manoeuvre, and in 3 children who h...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/BF02550317
更新日期：1998-01-01 00:00:00
abstract：OBJECTIVE:The current study was carried out to assess the effects of omega-3 fatty acid and alpha-tocopherol co-supplementation on malnutrition-inflammation score (MIS), biomarkers of inflammation and oxidative stress in chronic hemodialysis (HD) patients. METHODS:In a randomized double-blind placebo-controlled clinic...
journal_title：International urology and nephrology
pub_type： 杂志文章,随机对照试验
doi：10.1007/s11255-016-1399-4
更新日期：2016-11-01 00:00:00
abstract：PURPOSE:To investigate the effects of combined treatment of tadalafil (a phosphodiesterase-5 inhibitor) and tamsulosin (an α1-adrenoceptor antagonist) on bladder dysfunction in a rat model of bladder outlet obstruction (BOO). METHODS:Cystometry was performed in conscious female BOO rats 6 weeks after partially ligatio...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/s11255-018-1835-8
更新日期：2018-05-01 00:00:00
abstract：:Accurate knowledge about the morphology and degree of infiltration of a bladder tumor is an essential prerequisite to correctly plan, and forecast the results of, the treatment of these tumors. Among the radiological investigations double contrast cystography is superior to excretory cystogram or conventional cystogra...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/BF02082014
更新日期：1977-01-01 00:00:00
abstract：:We report a case of testicular microlithiasis in a 24-year-old man who was referred to us for evaluation of unclear ultrasonographic appearance of his testes while being examined for bilateral varicocele and epididymal cysts. Since testicular microlithiasis has been found to be associated with testicular germ cell tum...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/BF02550962
更新日期：1996-01-01 00:00:00
abstract：PURPOSE:Chronic kidney disease (CKD) is associated with a high incidence of obstructive sleep apnea (OSA). We assessed the effect of continuous positive airway pressure (CPAP) on renal function in patients with CKD and OSA. METHODS:In this retrospective cohort study, 42 patients with Stage 3-5 CKD and OSA were stratif...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/s11255-015-1113-y
更新日期：2015-11-01 00:00:00
abstract：:The recommended treatment for patients with severe bleeding from upper gastrointestinal (GI) metastases is embolisation. We report a case in which despite adequate embolisation major haemorrhage from renal cell carcinoma (RCC) gastric metastases continually recurred. During a severe bleed refractory to embolisation oc...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/s11255-005-0251-z
更新日期：2005-01-01 00:00:00
abstract：:A 75-year old man with long-term arterial hypertension was diagnosed in 1998 with stage 3 chronic kidney disease due to hypertensive nephropathy. Since May 2004 the patient has been treated with intermittent hemodialysis. Since 1998 he has been hospitalized several times because of palpitations in the course of paroxy...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/s11255-007-9302-y
更新日期：2009-01-01 00:00:00
abstract：OBJECTIVES:To assess whether conservative treatment of pediatric patients with neurogenic detrusor overactivity (NDO) results in lower bladder pressure and increased expected bladder volume (EBV), we investigated the clinical and urodynamic effects of long-term intravesical oxybutynin instillation compared with a stand...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/s11255-011-0030-y
更新日期：2012-04-01 00:00:00
abstract：BACKGROUND/AIMS:The aim of this work is to determine the long-term therapeutic benefit(s) of daclizumab induction therapy with triple immunosuppressive protocols including prednisolone, cyclosporine microemulsion (CsA), and mycophenolate mofetil (MMF) in the living related donor kidney transplantation. METHODS:Twenty-...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/s11255-006-9091-8
更新日期：2007-01-01 00:00:00
abstract：BACKGROUND:Chronic kidney disease (CKD) has been identified as a growing global burden and traditional health care systems are inadequate for the management of CKD patients. This paper describes an initiative to establish a renal management clinic (RMC) in China and discusses the challenges and opportunities in the man...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/s11255-008-9450-8
更新日期：2008-01-01 00:00:00
abstract：BACKGROUND:The adequate control of phosphataemia is of major importance in end-stage renal disease patients on maintenance dialysis. Recently, lanthanum carbonate (LC) has been added to the phosphate binder armamentarium. To our knowledge, no studies have yet evaluated the usefulness of this drug in uncontrolled hyperp...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/s11255-010-9860-2
更新日期：2012-02-01 00:00:00
abstract：PURPOSE:The development of a symptomatic lymphocele (SL) is a frequent postoperative surgical complication after kidney transplantation. It may lead to pain and discomfort and cause transplant malfunction or even secondary graft loss. A large cohort of renal recipients was investigated to identify the possible risk fac...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/s11255-019-02269-0
更新日期：2019-12-01 00:00:00
abstract：OBJECTIVE:The purpose was to evaluate the efficacy of the addition of short-term desmopressin to enuretic alarm in patients with primary monosymptomatic nocturnal enuresis (PMNE). MATERIALS AND METHODS:A total of 58 [corrected] children with PMNE were included in this study. The patients were randomized into two group...
journal_title：International urology and nephrology
pub_type： 杂志文章,随机对照试验
doi：10.1007/s11255-008-9355-6
更新日期：2008-01-01 00:00:00
