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Prospective randomized comparison of intravesical BCG therapy with standard dose versus low doses in superficial bladder cancer.

Abstract：

:In this study, we evaluated low dose intravesical bacillus Calmette-Guerin (BCG) therapy following transurethral resection (TUR) in 80 patients with superficial bladder cancer. The patients were divided into two groups. Of the Connaught BCG strain 81 mg was given to 40 patients in Group 1 and 54 mg to the remainder of 40 patients in Group 2. BCG was introduced once a week for 6 weeks. Tumour recurrence was seen in 6 patients in Group 1 and in 10 patients in Group 2. Recurrence rates per month were 0.71 and 1.49, respectively. There was no significant difference in complication rates. These data suggest that while the standard dose (81 mg) intravesical therapy of BCG is more effective than the low dose, there was no significant difference in side effects between the two groups.

journal_name

Int Urol Nephrol

journal_title

International urology and nephrology

authors

Yalçinkaya F,Kamiş L,Ozteke O,Günlüsoy B,Yigitbaşi O,Unal S

doi

10.1007/BF02550276

subject

Has Abstract

pub_date

1998-01-01 00:00:00

pages

41-4

issue

1

eissn

0301-1623

issn

1573-2584

journal_volume

30

pub_type

临床试验,杂志文章,随机对照试验

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