The Charlson Comorbidity Index: can it predict the outcome in acute kidney injury?

Abstract:

PURPOSE:Comorbidity has a significant impact on the health status and treatment outcome of a patient. The Charlson comorbidity index (CCI) is a frequently used scoring system, which evaluates the prognosis based on the patient's comorbid conditions. The aim of this study was to evaluate the usefulness of CCI in predicting the mortality and renal recovery in non-critically ill patients with severe AKI. METHODS:A total of 530 adult patients who were referred from the emergency department and underwent intermittent urgent hemodialysis (uHD) were enrolled in the study. Personal history for comorbidities were recorded and then assessed using the CCI. RESULTS:The mean CCI score was 3.3 ± 2.6. In our multivariate analysis, higher white blood cell count was associated with mortality (p = 0.023). The other parameters including CCI score were not found to be significantly associated with mortality excluding patients with sepsis. Moreover, the CCI was not significantly useful in the discrimination of patients with complete recovery from patients who remained dependent to dialysis. CONCLUSIONS:We could not find significant association between CCI and short-term hospital mortality and renal outcome. Whereas, malnutrition, inflammation and general aging may have impact on short-term mortality among patients.

journal_name

Int Urol Nephrol

authors

Yalin SF,Bakir A,Trabulus S,Seyahi N,Altiparmak MR

doi

10.1007/s11255-020-02499-7

subject

Has Abstract

pub_date

2020-09-01 00:00:00

pages

1713-1718

issue

9

eissn

0301-1623

issn

1573-2584

pii

10.1007/s11255-020-02499-7

journal_volume

52

pub_type

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