Abstract:
PURPOSE:The purpose of our study is to carry out a Bayesian network meta-analysis comparing the efficacy of different antimicrobial lock solutions (ALS) for prevention of catheter-related infections (CRI) in patients with hemodialysis (HD) and ranking these ALS for practical consideration. METHODS:We searched six electronic databases, earlier relevant meta-analysis and reference lists of included studies for randomized controlled trials (RCTs) that compared ALS for preventing episodes of CRI in patients with HD either head-to-head or against control interventions using non-ALS. Two authors independently assessed the methodological quality of included studies using the Cochrane risk of bias tool and extracted relevant information according to a predesigned extraction form. Data were analysed using the WinBUGS (V.1.4.3) and the Stata (V.13.0). RESULTS:Finally, 18 studies involving 2395 patients and evaluating 9 ALS strategies were included. Network meta-analysis showed that gentamicin plus citrate (OR 0.07, 95% CrI 0.00-0.48) and gentamicin plus heparin (OR 0.04, 95% CrI 0.00-0.23) were statistically superior to heparin alone in terms of reducing CRBSI. For exit site infection and all-cause mortality, no significant difference in the intervention effect (p > 0.05) was detected for all included ALS when compared to heparin. Moreover, all ALS were similar in efficacy (p > 0.05) from each other for CRBSI, exit site infection and all-cause mortality. CONCLUSIONS:Our findings indicated that gentamicin plus heparin may be selected for the prophylaxis of CRI in patients undergoing HD with CVCs. Whether this strategy will lead to antimicrobial resistance remains unclear in view of the relatively short duration of included studies. More attentions should be made regarding head-to-head comparisons of the most commonly used ALS in this field.
journal_name
Int Urol Nephroljournal_title
International urology and nephrologyauthors
Zhang J,Wang B,Li R,Ge L,Chen KH,Tian Jdoi
10.1007/s11255-016-1490-xsubject
Has Abstractpub_date
2017-04-01 00:00:00pages
701-716issue
4eissn
0301-1623issn
1573-2584pii
10.1007/s11255-016-1490-xjournal_volume
49pub_type
杂志文章,meta分析,评审abstract:UNLABELLED:We examined renal function and urinary drainage of children with primary megaureter (PMU) in dependence on conservative or operative treatment. MATERIAL AND METHODS:The retrospective analysis covering the years 1994 to 2000 comprised children at an age of 0-7 years with 35 PMU. Sonography, dynamic MAG3 reno...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-005-3615-5
更新日期:2006-01-01 00:00:00
abstract:PURPOSE:To assess clinical presentation and outcomes of different treatment strategies in cases of spontaneous renal hemorrhage (SRH). METHODS:A retrospective analysis of patients with SRH between 2000 and 2018 was performed. Patients' demographics, clinical presentation, laboratory and radiological investigations, an...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-019-02333-9
更新日期:2020-03-01 00:00:00
abstract:BACKGROUND:Although sleep complaints are commonly reported in persons with end stage renal disease (ESRD), little is known about the prevalence of sleep complaints in chronic kidney disease (CKD), and the relation of sleep quality to the severity of kidney disease. METHODS:We administered the Kidney Disease Quality of...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-004-4654-z
更新日期:2005-01-01 00:00:00
abstract::The prevalence of sleep disorders is significantly higher (up to 80%) in patients with chronic uremia compared to the general population. Sleep disorders appear even in the early stages of chronic kidney disease. These disturbances are complex, including difficulties in falling asleep and awakening, interrupted sleep,...
journal_title:International urology and nephrology
pub_type: 杂志文章,评审
doi:10.1007/s11255-007-9262-2
更新日期:2007-01-01 00:00:00
abstract:PURPOSE:Cardiovascular (CV) events are the first cause of death in patients with chronic renal disease (CKD) and in patients with type 2 diabetes mellitus (DM2). The combination of CKD and DM2 elevates the risk of both cardiovascular disease (CVD) and death in this high-risk population. Besides traditional risk factors...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-017-1755-z
更新日期:2018-02-01 00:00:00
abstract:PURPOSE:Five-year kidney graft loss currently stands at about 30%. We evaluate the clinical utility of a blood test measuring donor-derived cell-free DNA that detects rejection earlier and, potentially, improves diagnostic and therapeutic accuracy. METHODS:In a randomized controlled experiment, we measured the clinica...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-020-02491-1
更新日期:2020-08-01 00:00:00
abstract:INTRODUCTION:Renal function after renal surgery depends on the volume of renal parenchyma loss and improves in the postoperative period. However, the knowledge on kidney function after radical (RN) and partial (PN) nephrectomy is still insufficient. The aim of this study is to analyze the global renal function and comp...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-011-0058-z
更新日期:2012-06-01 00:00:00
abstract::Platinum (Pt) concentrations in the kidney and liver were determined in 12 autopsied cases following cisplatin treatment. The Pt level in the liver was generally higher than that in the kidney. Pt concentration in the liver showed a significant correlation with the total dose of cisplatin. However, no dose-dependent P...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:
更新日期:1993-01-01 00:00:00
abstract::In the management of infertility, in case semen quality is found insufficient and could not be improved by medical means, handling the available spermatozoa in the most beneficial way has been aimed. Thus, artificial insemination with low quality semen has become a therapeutic alternative. In this study homologous art...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02550148
更新日期:1996-01-01 00:00:00
abstract::Ureteroscopy is now in routine use for the diagnosis and treatment of various pathologies in the upper urinary tract. We report here on our experience in diagnostic and therapeutic applications of the 11.5 F rigid ureteroscope in 85 patients and 88 ureters. An overall success rate of 68.18% (60/88) was achieved when t...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02767719
更新日期:1994-01-01 00:00:00
abstract::We are presenting a 68-year-old female patient who was diagnosed to have a complete ureteral duplication and adenocarcinoma in the ureter which drained the upper moiety of the right kidney. ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1023/b:urol.0000025627.15113.e3
更新日期:2003-01-01 00:00:00
abstract:OBJECTIVES:Uroepithelium repair has always been the subject of discussion in urology surgeries. Using human amniotic membrane allograft has already proved to be useful in other fields. In this study, we use amniotic membrane to repair uroepithelium injuries in rabbits. METHODS:Twenty healthy rabbits underwent surgery ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-009-9532-2
更新日期:2009-12-01 00:00:00
abstract::Renal oncocytoma represents a special category of renal tumours and accounts for 3-5% of renal neoplasms. Usually they are incidental findings. Most reports have demonstrated their benign nature but a few cases of high-grade oncocytomas were reported to have metastasized. In Poland, between 1971 and 1991, 7 patients (...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02768007
更新日期:1994-01-01 00:00:00
abstract:OBJECTIVE:It has been shown that coenzyme Q(10) (CoQ(10)) supplementation in men with idiopathic oligoasthenoteratozoospermia (OAT) results in improved semen parameters. In present study, we evaluated the effects of coenzyme CoQ(10) supplementation on semen parameters and pregnancy rates in infertile men with idiopathi...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-011-0081-0
更新日期:2012-06-01 00:00:00
abstract::Ganglioneuroblastoma is a common type of tumor in children, but is rarely seen in adults. We present here a case of adrenal ganglioneuroblastoma in a 59-year old man. ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-004-0851-z
更新日期:2004-01-01 00:00:00
abstract:OBJECTIVE:To analyze the effect of age on nutrition indices in subjects on the same continuous ambulatory peritoneal dialysis (CAPD) schedule. METHODS:We analyzed 613 sets of clearance values and nutrition indices in 302 CAPD patients. Small solute clearances included urea clearance (Kt/Vurea) and creatinine clearance...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1023/a:1017579105158
更新日期:2001-01-01 00:00:00
abstract:OBJECTIVE:The prostatitis syndrome is a multifactorial condition of largely unknown etiology. This study is to analyze the relationship between cyclooxygenase-2 (COX-2) and prostaglandin E2 (PGE2) with the chronic nonbacterial prostatitis (CNBP). METHODS:A total of 172 CNBP patients and 151 healthy males were recruite...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-014-0743-9
更新日期:2014-10-01 00:00:00
abstract::This study presents a view of the knowledge the authors have gathered during 11 years of work with radioisotope examinations of the kidneys and ureteral urine passage performed in 34 children. As an important indication field they consider the conditions where excretory urography or separate functional examination, re...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02217144
更新日期:1980-01-01 00:00:00
abstract::We report a case of a urothelial carcinoma with trophoblastic differentiation of the bladder that occured in a 23-year-old man. The patient presented with hematuria. Multiple papillary masses were resected transurethrally. Histopathologically, grade III urothelial cell carcinoma contained giant cells that were positiv...
journal_title:International urology and nephrology
pub_type: 杂志文章,评审
doi:10.1007/s11255-004-0859-4
更新日期:2004-01-01 00:00:00
abstract:OBJECTIVE:To investigate whether stone dimension is a restrictive factor for ureterorenoscopic procedures. MATERIALS AND METHODS:A group of 416 patients who had undergone ureterorenoscopic pneumatic lithotripsy (URS-PL) for lower ureteral stones between January 1999 and June 2006 in our clinic had been evaluated retro...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-007-9278-7
更新日期:2008-01-01 00:00:00
abstract:OBJECTIVES:Preputial bacterial colonisation was investigated in preschool and primary school children with and without phimosis before the circumcision procedure. METHOD:The study group consisted of 32 boys admitted to our clinic consecutively between June 2003 and September 2003 for circumcision. The indication for s...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-004-4700-x
更新日期:2005-01-01 00:00:00
abstract::Fibrosing cholestatic hepatitis (FCH) is an uncommon complication of renal transplantation. It is usually associated with hepatitis B and C viral infection. It is further rare in renal transplantation in absence of HBV and HCV infection. To the best of our knowledge, only three cases of FCH in renal transplantation, w...
journal_title:International urology and nephrology
pub_type: 杂志文章,评审
doi:10.1007/s11255-004-6196-9
更新日期:2004-01-01 00:00:00
abstract::A surgical case of coexisting renal cyst and tumour is reported, diagnosis having been made preoperatively with the aid of two recent diagnostic procedures. Electron microscopic study of the surgical specimen revealed virus-like intranuclear particles in the malignant tissue. ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02081944
更新日期:1977-01-01 00:00:00
abstract::Experience in the treatment of urinary bladder cancer based upon observation of 306 cases has been presented. Two hundred and thirteen patients were treated surgically by performing in 151 cases partial cystectomy and in 62 cases total cystectomy. Conservative treatment was applied in 75 patients. In the authors' opin...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02082168
更新日期:1977-01-01 00:00:00
abstract::Multiloculated renal cell carcinoma and multilocular renal cyst with renal cell carcinoma are uncommon diseases. We report on 2 cases of multiloculated renal cell carcinoma. To our knowledge 16 cases of multiloculated renal cell carcinoma and multilocular renal cyst with renal cell carcinoma have been previously descr...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02583984
更新日期:1991-01-01 00:00:00
abstract:PURPOSE:Non-adherence (NA) to medication is a major contributor to treatment failure in hypertensive patients. Factors of the ecological model, at family/healthcare professional, service, and system levels, are rarely evaluated as correlates of NA in hypertensive patients. METHODS:This crossectional study assessed the...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-020-02755-w
更新日期:2021-01-16 00:00:00
abstract::Reduced peritoneal clearances of creatinine and urate were demonstrated repeatedly in a patient with scleroderma and a patient with diabetes mellitus. Urea clearances were not significantly different from usual values. The findings suggest decreased peritoneal membrane permeability and/or area (if urea clearance is fl...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02082213
更新日期:1976-01-01 00:00:00
abstract::The aim of this study was to investigate the hormonal and hemodynamic changes during percutaneous nephrolithotomy (PCNL) procedure. Twenty-one patients between 15-65 years of age were included in the study. Invasive blood pressure and heart rate were monitored during PCNL. Serum sodium, potassium, BUN and creatinine l...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1023/a:1017527126481
更新日期:2001-01-01 00:00:00
abstract:PURPOSE:Varicocele is among the leading causes of male infertility. Despite decades of research, its pathogenesis is still unclear. S100A12 is a member of the S100 family of calcium-binding proteins with principal extracellular activities. It is secreted by activated neutrophils and interacts with the multiligand recep...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-015-1188-5
更新日期:2016-03-01 00:00:00
abstract::We report a case of 20-year-old farmer with penile amputation and emasculation secondary to crushing injury inflicted by agricultural machinery. His entire penis, scrotum and both the testis had been avulsed after falling onto a rotating axel wheel of an electronically driven thrashing machine. After resuscitation the...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-004-0918-x
更新日期:2004-01-01 00:00:00