Abstract:
INTRODUCTION:Renal function after renal surgery depends on the volume of renal parenchyma loss and improves in the postoperative period. However, the knowledge on kidney function after radical (RN) and partial (PN) nephrectomy is still insufficient. The aim of this study is to analyze the global renal function and compensatory hyperfunction of the non-operated kidney in patients with renal cancer after RN or PN. METHODS:Fifty-one patients of mean age 62.2 years with renal cancer were included. Thirty-three RN and eighteen PN were performed. We measured creatinine serum concentrations, and we estimated glomerular filtration rate (eGFR) preoperatively and postoperatively at two time intervals: 3 and 12 months after surgery. Additionally, we assessed effective renal plasma flow (ERPF) in dynamic scintigraphy preoperatively and 12 months after surgery. RESULT:At the baseline, all mean measured values were comparable in RN and PN groups (P > 0.05). Three months after surgery, creatinine level increased in both groups, more remarkably in RN group (128 mmol/l vs. 95 mmol/l; P < 0.05), while eGFR diminished (47 ml/min/1.73 m(2) vs. 70 ml/min/1.73 m(2); P < 0.05). Similar biochemical values were observed 12 months after surgery. The mean ERPF of the non-operated kidney 12 months after surgery in RN and PN groups increased by 3.8% (232 ml/min) and 0.1% (200 ml/min), respectively (P > 0.05). The mean ERPF of the operated kidney in PN group decreased by 24.7% (149 ml/min). CONCLUSION:The deterioration of renal function after partial nephrectomy is nearly insignificant clinically. In 1-year postoperative observation, the renal function does not improve. This causes potential compensatory mechanisms to be insufficient.
journal_name
Int Urol Nephroljournal_title
International urology and nephrologyauthors
Antoniewicz AA,Poletajew S,Borówka A,Pasierski T,Rostek M,Pikto-Pietkiewicz Wdoi
10.1007/s11255-011-0058-zsubject
Has Abstractpub_date
2012-06-01 00:00:00pages
745-51issue
3eissn
0301-1623issn
1573-2584journal_volume
44pub_type
杂志文章abstract::We report a case of 20-year-old farmer with penile amputation and emasculation secondary to crushing injury inflicted by agricultural machinery. His entire penis, scrotum and both the testis had been avulsed after falling onto a rotating axel wheel of an electronically driven thrashing machine. After resuscitation the...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-004-0918-x
更新日期:2004-01-01 00:00:00
abstract:OBJECTIVE:Supracostal superior calyceal access has been shown to be the most suitable approach for staghorn calculi, calculi in the upper ureter, and complex inferior calyceal calculi. It is a good choice for direct access for most of the intrarenal collecting system and upper ureter. The aim of this retrospective stud...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-011-9916-y
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abstract:PURPOSE:A region of chromosome 22 which includes APOL1 and MYH9 genes was recently identified as a risk locus for non-diabetic forms of kidney disease, including idiopathic and HIV-associated focal segmental glomerular sclerosis and kidney disease clinically attributed to hypertension among African Americans. The purpo...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-012-0263-4
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abstract::We report on our experience with a new surgical procedure of forming a pseudoneotesticle from indigenous tissues obtained from the existing scrotal contents. This procedure has been performed in 32 patients with a diagnosis of hormone dependent cancer of the prostate as a therapeutic manoeuvre, and in 3 children who h...
journal_title:International urology and nephrology
pub_type: 杂志文章
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更新日期:1998-01-01 00:00:00
abstract:OBJECTIVE:The prostatitis syndrome is a multifactorial condition of largely unknown etiology. This study is to analyze the relationship between cyclooxygenase-2 (COX-2) and prostaglandin E2 (PGE2) with the chronic nonbacterial prostatitis (CNBP). METHODS:A total of 172 CNBP patients and 151 healthy males were recruite...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-014-0743-9
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journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-017-1732-6
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journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02768286
更新日期:1994-01-01 00:00:00
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journal_title:International urology and nephrology
pub_type: 杂志文章
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journal_title:International urology and nephrology
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journal_title:International urology and nephrology
pub_type: 杂志文章
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journal_title:International urology and nephrology
pub_type: 临床试验,杂志文章
doi:
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journal_title:International urology and nephrology
pub_type: 临床试验,杂志文章
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journal_title:International urology and nephrology
pub_type: 杂志文章
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journal_title:International urology and nephrology
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journal_title:International urology and nephrology
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更新日期:2021-01-03 00:00:00
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journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02552189
更新日期:1997-01-01 00:00:00
abstract:INTRODUCTION:Factors responsible for the low incidence of clinical prostate cancer (3-8/100,000 men/year) in the Arab population remain unclear, but may be related to changes in steroid hormone metabolism. We compared the levels of serum conjugated and unconjugated steroids between Arab and Caucasian populations, to de...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-005-3619-1
更新日期:2006-01-01 00:00:00
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journal_title:International urology and nephrology
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journal_title:International urology and nephrology
pub_type: 杂志文章
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journal_title:International urology and nephrology
pub_type: 杂志文章
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journal_title:International urology and nephrology
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abstract::Splenogonadal fusion is a rare congenital non-malignant anomaly characterized by fusion of splenic tissue to the gonad and can be continuous or discontinuous. Very few cases have been diagnosed preoperatively. We reported one case of the continuous type presenting with scrotal mass which underwent laparoscopy and the ...
journal_title:International urology and nephrology
pub_type: 杂志文章
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更新日期:2013-02-01 00:00:00
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journal_title:International urology and nephrology
pub_type: 杂志文章
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pub_type: 杂志文章
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pub_type: 临床试验,杂志文章
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journal_title:International urology and nephrology
pub_type: 杂志文章
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journal_title:International urology and nephrology
pub_type: 杂志文章
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更新日期:2000-01-01 00:00:00
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pub_type: 杂志文章,meta分析,评审
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更新日期:2017-01-01 00:00:00