Abstract:
PURPOSE:To investigate whether an elevated serum uric acid (SUA) level is an independent risk factor for rapid decline in renal function or new-onset chronic kidney disease (CKD) in a Chinese health checkup population. METHODS:A cohort study of 6495 Chinese individuals who underwent health checkups with normal estimated glomerular filtration rate (eGFR) at baseline was carried out from May 2011 to April 2016. Examinations included a questionnaire, physical measurements, and blood sampling. The gender-specific quartiles of blood uric acid were used to present baseline descriptive data. Rapid decline of renal function was defined as eGFR loss of > 3 mL/min/1.73 m2/year. New-onset CKD was defined as follow-up eGFR < 60 mL/min/1.73 m2 or positive proteinuria. Multivariable logistic regression was used to assess the relationship between serum uric acid and the following outcomes: rapid decline of renal function, incident CKD, and combined renal outcomes. RESULTS:During mean follow-up of 52.8 months, 1608 (24.8%) individuals reached combined renal events. Rapid decline in renal function developed in 1506 (23.2%) individuals, and incident CKD was documented in 372 (5.7%) individuals. In a multivariate model adjusted for age, BMI, diabetes, hypertension, alcohol drinking, SBP, total cholesterol, and eGFR, the odds ratio for rapid decline of renal function increased across quartiles of serum uric acid level, reaching a 1.32 (95% CI 1.02-2.97) for the top quartile compared to the lowest quartile (P for trend < 0.001). Meanwhile, higher SUA was also associated with incident CKD in all models. Furthermore, an increased risk of reaching renal outcomes across increasing quartiles of SUA levels appeared to be similar among subgroups stratified according to age, eGFR, and SBP (P < 0.05 in all). CONCLUSIONS:These findings suggest that higher SUA may predict progressive renal damage and dysfunction in a health checkup population in China.
journal_name
Int Urol Nephroljournal_title
International urology and nephrologyauthors
Cao X,Wu L,Chen Zdoi
10.1007/s11255-017-1732-6subject
Has Abstractpub_date
2018-03-01 00:00:00pages
517-525issue
3eissn
0301-1623issn
1573-2584pii
10.1007/s11255-017-1732-6journal_volume
50pub_type
杂志文章abstract::Seventy-one women suffering from recurrent cystitis were analysed. The patients were randomly distributed into two groups, in accordance with the treatment given. Forty-one were treated medically and thirty were subjected to internal urethrotomy with the Otis urethrotome and antimicrobial agents. The results of treatm...
journal_title:International urology and nephrology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/BF02217138
更新日期:1980-01-01 00:00:00
abstract::Bilateral vasovasostomies were performed in 7 previously vasectomized patients. The method employed was a modification of a one-layer anastomotic technique. There was no correlation between the presence of absence of sperm in the vas fluid, presence or absence of sperm granuloma, and site of vasectomy. No correlation ...
journal_title:International urology and nephrology
pub_type: 临床试验,杂志文章
doi:10.1007/BF02550083
更新日期:1995-01-01 00:00:00
abstract:AIMS:Sacral neurostimulation (SNS) involves a two-stage procedure to assess outcomes prior to permanent implantation. Stage 1 involves placement of a sacral lead that is externalized and tested for 2 weeks. Stage 2 is the implantation of a pulse generator in responders (≥ 50% improved). This study's purpose was to dete...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-011-9919-8
更新日期:2011-12-01 00:00:00
abstract:BACKGROUND:The use of anabolic steroids and vitamin supplements has reached alarming proportions in the last decades. Adverse effects have been documented and include virilization, feminization, adverse lipid profile, psychiatric disorders, cardiac and liver disease. Acute kidney injury (AKI) is not frequently describe...
journal_title:International urology and nephrology
pub_type: 杂志文章,评审
doi:10.1007/s11255-009-9571-8
更新日期:2009-01-01 00:00:00
abstract:PURPOSE:To survey long-term outcomes of dialysis patients with urothelial cancers who have undergone complete urinary tract exenteration (bilateral nephroureterectomy and cystectomy). METHODS:We retrospectively reviewed our patients with urinary tract urothelial cancer. Forty-two dialysis patients who underwent comple...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-017-1522-1
更新日期:2017-04-01 00:00:00
abstract:PURPOSE:In this prospective study we aimed to describe our new technique; dehydrated human dura mater as an interposition graft in patients undergoing benign vesicovaginal fistula repair (VVF). PATIENTS AND METHODS:Eleven patients with benign VVFs aged 38-73 years were operated with dura mater interposition technique ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1023/b:urol.0000032682.84973.e9
更新日期:2004-01-01 00:00:00
abstract:INTRODUCTION:The aim of this study was to assess the feasibility of robotic assisted kidney transplantation in graft with multiple vessels. MATERIALS AND METHODS:Eighteen patients underwent RAKT with grafts with multiple vessels (GMVs) from living donor performed by a single surgeon in single institution. The retrospe...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-019-02305-z
更新日期:2020-02-01 00:00:00
abstract:OBJECTIVES:Metformin has been shown to reduce diabetic complications in overweight patients, and is increasingly used to treat this condition. However, this agent is associated with a rare but serious risk of lactic acidosis. METHODS:From January 2004 to November 2008, 11 cases of metformin-associated lactic acidosis ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-009-9549-6
更新日期:2009-12-01 00:00:00
abstract::In the course of a disinterment of an ancient Avar burial place at Székkutas-Kápolna near Hódmezövásárhely, Hungary, the archaeologist conducting the excavations, Miss Katalin B. Nagy, noticed a lithoid body of oval shape in the pelvis of a skeleton. The find was identified on morphological and chemo-analytical ground...
journal_title:International urology and nephrology
pub_type: 历史文章,杂志文章
doi:10.1007/BF02550466
更新日期:1987-01-01 00:00:00
abstract::Nonfunctional carcinomas of the adrenal gland are quite rare. By presenting a 47-year-old woman with such a tumour, a review of the literature is made, with special emphasis on the epidemiology and histologic criteria in predicting malignant behaviour. In addition, the clinical, pathological and radiographic findings,...
journal_title:International urology and nephrology
pub_type: 杂志文章,评审
doi:10.1007/BF02550852
更新日期:1996-01-01 00:00:00
abstract:OBJECTIVES:Progression of the cell cycle is regulated by the interactions of cyclins, cyclin dependent kinases (CDKs) and CDK inhibitors (CDKIs). p27 is a member of the universal cyclin-dependent kinase inhibitor family. The level of p27 protein expression decreases during tumor development and progression in some epit...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1023/b:urol.0000020301.39181.03
更新日期:2003-01-01 00:00:00
abstract::During transurethral electroresection in the posterolateral bladder neck, trigone and posterior urethra, unintentional contractions of the thigh-adductor muscles may occur due to irritation of the obturator nerve. The sudden displacement of the bladder wall against the cutting loop may cause a perforation of the bladd...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02085445
更新日期:1983-01-01 00:00:00
abstract:OBJECTIVE:The prostatitis syndrome is a multifactorial condition of largely unknown etiology. This study is to analyze the relationship between cyclooxygenase-2 (COX-2) and prostaglandin E2 (PGE2) with the chronic nonbacterial prostatitis (CNBP). METHODS:A total of 172 CNBP patients and 151 healthy males were recruite...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-014-0743-9
更新日期:2014-10-01 00:00:00
abstract:AIM:To determine the effectiveness of transdermal electromotive administration (TEA) of verapamil and dexamethasone in the treatment of Peyronie's disease (PD). METHOD:Totally, 51 patients with PD were prospectively included in the study. All patients were evaluated by history, subjective score scales, physical examin...
journal_title:International urology and nephrology
pub_type: 临床试验,杂志文章
doi:10.1007/s11255-008-9408-x
更新日期:2009-01-01 00:00:00
abstract:OBJECTIVES:Uroepithelium repair has always been the subject of discussion in urology surgeries. Using human amniotic membrane allograft has already proved to be useful in other fields. In this study, we use amniotic membrane to repair uroepithelium injuries in rabbits. METHODS:Twenty healthy rabbits underwent surgery ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-009-9532-2
更新日期:2009-12-01 00:00:00
abstract:OBJECTIVE/BACKGROUND:The aim of this study was to evaluate the efficacy of the autologous fascia rectus sling in treating stress urinary incontinence in female patients with neuropathic bladder. Furthermore, correlations between preoperative parameters and outcome were evaluated. METHODS AND DESIGN:We retrospectively ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-012-0247-4
更新日期:2012-10-01 00:00:00
abstract::The recommended treatment for patients with severe bleeding from upper gastrointestinal (GI) metastases is embolisation. We report a case in which despite adequate embolisation major haemorrhage from renal cell carcinoma (RCC) gastric metastases continually recurred. During a severe bleed refractory to embolisation oc...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-005-0251-z
更新日期:2005-01-01 00:00:00
abstract:PURPOSE:To determine the effectiveness of Vacuum-Assisted Closure Device in the postoperative wound care for Fournier's gangrene METHODS: We performed a systematic review in the following databases: Medline (Ovid), EMBASE, and The Cochrane Central Register of Controlled Trials (CENTRAL), from inception to nowadays. We ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-020-02705-6
更新日期:2020-11-13 00:00:00
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journal_title:International urology and nephrology
pub_type: 杂志文章,评审
doi:10.1007/s11255-014-0808-9
更新日期:2014-09-01 00:00:00
abstract::We report a case of penile incarceration in a 53-year-old impotent man. The base of the penis was encircled by a metal ring in order to achieve better erection. There was marked oedema of the entire penis distal to the constricting ring. The metal ring was removed successfully by cutting it with a steel saw. ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02564752
更新日期:1995-01-01 00:00:00
abstract::It is well known that some antibiotics are particularly nephrotoxic. In the present study we investigated kidney function and AAP excretion (as an index of nephrotoxicity) in patients with urinary tract infection treated with CAZ or CTX plus TOB. The main cause of infection was E. coli in both treated groups. After 10...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02550604
更新日期:1988-01-01 00:00:00
abstract:PURPOSE:Reusable flexible-ureteroscopes (fURS) require personnel and budget for processing and repairing, whereas single-use fURS were recently developed. After exclusive reusable fURS since 2011, we experienced high repair costs and single-use fURS were therefore introduced in mid-2017. We aimed to evaluate economic a...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-019-02230-1
更新日期:2019-10-01 00:00:00
abstract:OBJECTIVE:To describe our experience with Hydro-Jet-assisted laparoscopic partial nephrectomy (LPN) with no renal arterial clamping in 35 patients with renal cell carcinoma. METHODS:Hydro-Jet technique was used to incise the renal parenchyma, dissect the intrarenal vessels and collecting system during the LPN procedur...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-014-0670-9
更新日期:2014-07-01 00:00:00
abstract::The incidence of cytomegalovirus infection in Chinese patients was reviewed in a retrospective study of 99 renal transplant recipients. CMV infection occurred in 18 patients (18.2%). In 4 the infection was considered primary and in 14 it was thought to be reactivation. Of the infections 88.9% occurred within the first...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02767664
更新日期:1994-01-01 00:00:00
abstract:PURPOSE:Control of hydration status is an important constituent of adequate and efficient hemodialysis (HD) treatment. Nevertheless, there are no precise clinical indices for early recognition of small changes in fluid status of patients undergoing chronic hemodialysis therapy. This study aimed to evaluate and compare ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-016-1473-y
更新日期:2017-03-01 00:00:00
abstract::The paper deals with the authors' own experience in endoscopic treatment of urethrostenosis in males. Since 1980, 86 patients have been treated in this manner. Good results were obtained in 60 (70%) after one surgical procedure and in 18 (21%) after two operations. Two patients were operated upon by routine methods. W...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02550611
更新日期:1988-01-01 00:00:00
abstract::To remove multiple calyceal stones percutaneously is not a simple task. During the act of dilating the pierced channel the stones are apt to drift away towards other parts of the renal cavitary system. For avoidance we recommend the use of Pyeloform, a bicomponent synthetic compound in which chemical reaction between ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:
更新日期:1993-01-01 00:00:00
abstract::Behcet's disease (BD) is a rare chronic, relapsing, multisystemic disorder characterized by mucocutaneous, ocular, vascular and central nervous system manifestations. However, the etiopathogenesis of the disease remains unknown, and diagnosis is basically dependent on clinical manifestations. Sometimes BD may be diagn...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-013-0519-7
更新日期:2014-02-01 00:00:00
abstract::To report a rare congenital anomaly of the genitourinary tract, renal dysplasia is associated with ipsilateral incomplete duplicated ectopic ureter and seminal vesicle cyst in an adult, successfully treated with robotic-assisted laparoscopic approach. ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-013-0412-4
更新日期:2013-06-01 00:00:00
abstract:PURPOSE:We examined the incidence of myocardial ischemia (MI) in kidney transplant recipients (KTR) using myocardial perfusion imaging (MPI), and its association with long-term outcomes after transplantation. METHODS:A retrospective observational study was conducted of asymptomatic KTRs who underwent post-transplant M...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-020-02542-7
更新日期:2020-10-01 00:00:00