Abstract:
:While the symptomology of underactive bladder (UAB) may imply a primary dysfunction of the detrusor muscle, insights into pathophysiology indicate that both myogenic and neurogenic mechanisms need to be considered. Due to lack of proper animal models, the current understanding of the UAB pathophysiology is limited, and much of what is known about the clinical etiology of the condition has been derived from epidemiological data. We hereby review current state of the art in the understanding of the pathophysiology of and animal models used to study the UAB.
journal_name
Int Urol Nephroljournal_title
International urology and nephrologyauthors
Tyagi P,Smith PP,Kuchel GA,de Groat WC,Birder LA,Chermansky CJ,Adam RM,Tse V,Chancellor MB,Yoshimura Ndoi
10.1007/s11255-014-0808-9subject
Has Abstractpub_date
2014-09-01 00:00:00pages
S11-21eissn
0301-1623issn
1573-2584journal_volume
46 Suppl 1pub_type
杂志文章,评审abstract:BACKGROUND:There is evidence that chronic local ischemia may be one possible etiology of prostatic atrophy (PA). Our aim was to study the expression of hypoxia induced factors in areas of PA. DESIGN:The immunohistochemical expression of hypoxia-inducible factor-1 alpha (HIF-1) and vascular endothelial growth factor (V...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-006-6657-4
更新日期:2006-01-01 00:00:00
abstract::In this study, 31 (30%) cases of urinary tract infection (UTI) of 103 patients with malnutrition, who were admitted to our hospital, were investigated prospectively. Our purpose was to determine the frequency of UTI, species of bacteria caused to infection and their antibiotic susceptibility in infants with malnutriti...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1023/a:1007104326689
更新日期:2000-01-01 00:00:00
abstract::The incidence of cytomegalovirus infection in Chinese patients was reviewed in a retrospective study of 99 renal transplant recipients. CMV infection occurred in 18 patients (18.2%). In 4 the infection was considered primary and in 14 it was thought to be reactivation. Of the infections 88.9% occurred within the first...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02767664
更新日期:1994-01-01 00:00:00
abstract:OBJECTIVE/BACKGROUND:The aim of this study was to evaluate the efficacy of the autologous fascia rectus sling in treating stress urinary incontinence in female patients with neuropathic bladder. Furthermore, correlations between preoperative parameters and outcome were evaluated. METHODS AND DESIGN:We retrospectively ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-012-0247-4
更新日期:2012-10-01 00:00:00
abstract::Kidney transplantation provides the best outcome for patients with end-stage renal failure both in terms of morbidity and mortality and health-related quality of life (QoL). Health-related QoL has become recognized as an important outcome measure in patients with different chronic medical conditions, including chronic...
journal_title:International urology and nephrology
pub_type: 杂志文章,评审
doi:10.1007/s11255-009-9527-z
更新日期:2009-01-01 00:00:00
abstract::Administration of intravenous iron to supplement erythropoiesis stimulating agents (ESAs) has become a common practice in the management of anemia in patients with end-stage renal disease. Randomized clinical trials of anemia correction in this population have shown more adverse outcomes in CKD and ESRD patients assig...
journal_title:International urology and nephrology
pub_type: 杂志文章,评审
doi:10.1007/s11255-011-0028-5
更新日期:2012-04-01 00:00:00
abstract:OBJECTIVE:To determine the prostate specific antigen (PSA) population standards of a cluster of Turkish men with no clinical evidence of prostate cancer. PATIENTS AND METHODS:We evaluated PSA values of the men who were living in a well-defined, rural district of Western Anatolia. Two hundred fifty-seven men agreed to ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-004-7976-y
更新日期:2005-01-01 00:00:00
abstract:BACKGROUND:General and spinal anesthesia are currently in widespread use during transurethral bladder tumor resection. However, local anesthetic methods are claimed to provide sufficient intra-operative analgesia and satisfactory post-operative pain management. We evaluated whether local levobupivacaine infiltration of...
journal_title:International urology and nephrology
pub_type: 杂志文章,随机对照试验
doi:10.1007/s11255-007-9295-6
更新日期:2008-01-01 00:00:00
abstract:PURPOSE:We aimed to evaluate the efficacy of Lachance formula and more readily available clinical or laboratory factors (other than serum methanol level) in prediction of the needed time for hemodialysis in methanol-poisoned patients. METHODS:In a retrospective study, all methanol-poisoned patients referred to us betw...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-017-1521-2
更新日期:2017-06-01 00:00:00
abstract:BACKGROUND:We reviewed our experience with ureteral complications and secondary ureteral implantation after kidney transplantation. METHODS:Between 1997 and 2005, 636 patients underwent kidney transplantation at our transplant center. Ureteral implantation was performed in the Lich-Gregoire technique. Thirty-one patie...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-010-9893-6
更新日期:2011-09-01 00:00:00
abstract:PURPOSE:In mouse models of prostate cancer, increased epinephrine levels accelerated tumor growth via the beta2-adrenoreceptor/PKA signaling pathway. It is unknown, however, whether men experience increased epinephrine levels sufficient to activate the beta2-adrenoreceptor/PKA pathway in the prostate gland. We measured...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-013-0513-0
更新日期:2014-03-01 00:00:00
abstract:BACKGROUND:Bladder neck contracture (BNC) following prostatectomy has been reported in 0.5-32% of cases. While the etiology of a BNC is unclear, several factors have been associated with this complication, including blood loss, devascularization of bladder neck tissue, poor mucosal apposition and urinary extravasation....
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-007-9239-1
更新日期:2008-01-01 00:00:00
abstract:PURPOSE:The impact of radical surgery for urothelial carcinoma is significant on patient's quality of life. Organ-sparing surgery (OSS) can provide comparable oncological outcomes and with improved quality of life. In this review, we summarize the indications, techniques and outcomes of OSS for these tumors. METHODS:P...
journal_title:International urology and nephrology
pub_type: 杂志文章,评审
doi:10.1007/s11255-019-02232-z
更新日期:2019-11-01 00:00:00
abstract:OBJECTIVE:To determine predictors for surgical complications and assess patient satisfaction after surgical treatment of Adult-Acquired Buried Penis (AABP). METHODS:A retrospective review was performed on all patients diagnosed with AABP who underwent surgical treatment at a single institution from January 2013-Decemb...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-019-02347-3
更新日期:2020-04-01 00:00:00
abstract::The urethral syndrome is generally not associated clinically with urethral changes, however, histology often reveals inflammatory or degenerative alterations. The conventionally diagnosed urethral syndrome can certainly be considered to be a synonym of chronic urethritis in adult females. The remarkable histological l...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02082229
更新日期:1979-01-01 00:00:00
abstract::Renal oncocytoma represents a special category of renal tumours and accounts for 3-5% of renal neoplasms. Usually they are incidental findings. Most reports have demonstrated their benign nature but a few cases of high-grade oncocytomas were reported to have metastasized. In Poland, between 1971 and 1991, 7 patients (...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02768007
更新日期:1994-01-01 00:00:00
abstract:PURPOSE:Hypoxia plays a significant role in the pathogenesis of acute kidney injury (AKI). Autophagy protects from AKI. Amino acid deprivation induces autophagy. The effect of L-tryptophan depletion on survival and autophagy in cultures of renal proximal tubular epithelial cells (RPTECs) under hypoxia was evaluated. M...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-017-1596-9
更新日期:2017-07-01 00:00:00
abstract:BACKGROUND:It has been shown that residual renal function but not peritoneal clearance predicted patients' survival in peritoneal dialysis therapy. In the present study, we tried to explore the potential causes resulting in the difference between residual renal function and peritoneal dialysis in continuous ambulatory ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-005-4011-x
更新日期:2005-01-01 00:00:00
abstract::Serum renin concentration (SRC) was determined in 97 hypertensive patients under basal conditions and during stimulation of renin secretion. Renin secretion was stimulated by upright posture and by either of the following means: (a) diet containing 20 mEq Na/24 hours for 3 days; (b) 300 mg i.v. diazoxide injections; (...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02082246
更新日期:1976-01-01 00:00:00
abstract::The follow-up study has been performed in 4 male patients with nephrogenic diabetes insipidus lasting for 4 to 15 years. Hydronephrosis or hydroureter appeared to be caused by polyuria with or without urinary tract obstruction. The efficacy of drainage operation is emphasized when polyuria surpasses the transporting a...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02549772
更新日期:1990-01-01 00:00:00
abstract::Protein Z (PZ) is a vitamin K-dependent protein isolated from human and bovine plasmas. Although the exact role of PZ in the haemostatic system is presently unknown, it is suggested that PZ deficiency may cause bleeding tendency. Haemostatic alterations in end-stage renal failure (ESRF) are certainly complex and invol...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1023/a:1007179631603
更新日期:1999-01-01 00:00:00
abstract:PURPOSE:The development of a symptomatic lymphocele (SL) is a frequent postoperative surgical complication after kidney transplantation. It may lead to pain and discomfort and cause transplant malfunction or even secondary graft loss. A large cohort of renal recipients was investigated to identify the possible risk fac...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-019-02269-0
更新日期:2019-12-01 00:00:00
abstract::Experience in the treatment of urinary bladder cancer based upon observation of 306 cases has been presented. Two hundred and thirteen patients were treated surgically by performing in 151 cases partial cystectomy and in 62 cases total cystectomy. Conservative treatment was applied in 75 patients. In the authors' opin...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02082168
更新日期:1977-01-01 00:00:00
abstract::Tubular reabsorption of magnesium ( TRMg ) was calculated from the values of plasma ultrafiltrable Mg and urinary Mg in 36 patients with transplanted kidneys. The study revealed a defect in TRMg in all investigated patients. The lowest TRMg values were found in patients with poor function of the transplanted kidneys. ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02082706
更新日期:1984-01-01 00:00:00
abstract::Among 104 patients with urethral strictures treated over a period of 3 years, sixty-five (63%) had complications such as inflammatory periurethral mass, watering-can perineum with discharging sinuses and fistulas, associated urethral calculi, periurethral abscesses and urethral diverticula. Seventy-four per cent of th...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02549587
更新日期:1989-01-01 00:00:00
abstract::A patient with bladder carcinoma, subjected to cystectomy and bilateral ureterosigmoidostomy, survived for the length of 31 years. The Coffey method of anastomosis was applied in a form modified by the authors. The patient succumbed to acute circulatory insufficiency at the age of 85. Metastases were not discovered ei...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02081864
更新日期:1984-01-01 00:00:00
abstract:PURPOSE:We compared the accuracy of magnetic resonance (MR) urethrography and X-ray urethrography with operative findings for urethral strictures and observed their effects on treatment. MATERIALS AND METHODS:A total of 87 male patients (10-85 years of age) treated from January 2015 to December 2016 were included in t...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-019-02162-w
更新日期:2019-07-01 00:00:00
abstract::Register and Multicenter Study for Testicular Tumours Bonn was founded in September 1976. Until August 1981, from 46 institutions participating in Austria and the Federal Republic of Germany the data from a total of 1508 patients with testicular tumours have been collected and evaluated. This paper gives an overview o...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02082779
更新日期:1984-01-01 00:00:00
abstract::This study was designed to investigate the relationship between the effects of testicular reactive oxygen species (ROS) levels and testicular histology on infertile patients with the aid of xanthine oxidase system and testicular tissue malondialdehyde levels. Forty patients with idiopathic infertility constituted our ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1023/a:1007138522517
更新日期:1999-01-01 00:00:00
abstract::Infertility may occur in patients with unilateral testicular torsion whose contralateral testis is intact. Depending on this observation, the physicians have begun to examine the contralateral testis. In the present prospective study we aimed to examine the histopathologic alterations occurring in the contralateral te...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02550935
更新日期:1997-01-01 00:00:00