Long-term effects of steroid and cytostatic treatment on the clinical course of idiopathic membranous glomerulonephritis (retrospective study).

Abstract:

:The clinical course of 30 patients with idiopathic membranous glomerulonephritis has been followed up for 8.1 +/- 3.4 (4-17) years. First, in each case a long-term prednisone treatment was administered. During this therapy 12 (40%) patients improved and 9 had remission. In the 18 (60%) steroid resistant cases the treatment was combined with cytostatic drugs. After a combined regime for 1.9 +/- 0.8 years, 8 patients have improved, 2 of whom remitted. It has been suggested that due to a long-term immunomodulator therapy the level of urinary protein excretion might be reduced in 77% of patients. There was no effect of the applied treatment in 7% of cases, still in 16% a gradual deterioration was observed. Relapsing nephrotic syndrome has occurred in 3 (10%) of the total cases. Side effects requiring cessation of treatment were not observed.

journal_name

Int Urol Nephrol

authors

Mohácsi G,Magori A,Sonkodi S

doi

10.1007/BF02549523

subject

Has Abstract

pub_date

1988-01-01 00:00:00

pages

315-25

issue

3

eissn

0301-1623

issn

1573-2584

journal_volume

20

pub_type

杂志文章
  • Multivariate evaluation of prognostic determinants for renal cell carcinomas which are metastatic at initial diagnosis.

    abstract::To clarify the relative importance of clinicopathological factors potentially affecting the survival of individuals initially diagnosed as having metastatic renal cell carcinoma (RCC), univariate and multivariate analyses using Cox's proportional hazards model were performed for 111 RCC patients who were admitted to f...

    journal_title:International urology and nephrology

    pub_type: 杂志文章

    doi:10.1007/BF02550925

    authors: Takashi M,Kawai T,Murase T,Wakai K,Ohno Y

    更新日期:1997-01-01 00:00:00

  • Experiences in treating cancer of the bladder.

    abstract::Experience in the treatment of urinary bladder cancer based upon observation of 306 cases has been presented. Two hundred and thirteen patients were treated surgically by performing in 151 cases partial cystectomy and in 62 cases total cystectomy. Conservative treatment was applied in 75 patients. In the authors' opin...

    journal_title:International urology and nephrology

    pub_type: 杂志文章

    doi:10.1007/BF02082168

    authors: Wojewski A,Zajaczkowski T

    更新日期:1977-01-01 00:00:00

  • Role of phosphate in experimental uraemia.

    abstract::Serum, corpuscular and renal tissue phosphate (Pi) concentrations in normal and chronic renal failure rats were examined. A significant correlation was found between Pi levels and indications of renal function. In addition, there were significant relationships between phosphate levels and RBC, Hb, Hct, serum Fe, serum...

    journal_title:International urology and nephrology

    pub_type: 杂志文章

    doi:

    authors: Hosokawa S,Yoshida O

    更新日期:1993-01-01 00:00:00

  • Conservative management of post-transplant central nervous system lymphoma.

    abstract::Primary CNS lymphoma (PCNSL) is a rare B cell variant non-Hodgkins lymphoma that is confined to the brain, leptomeninges, spinal cord and eyes. Its incidence is increasing, primarily due to increase in the number of organ transplantations being undertaken. The majority of the PTLD (post-transplant lymphoproliferative ...

    journal_title:International urology and nephrology

    pub_type: 杂志文章,评审

    doi:10.1007/s11255-012-0146-8

    authors: Valavoor SH,Ashraf Z,Narwal R,Ratnam S

    更新日期:2013-08-01 00:00:00

  • Comparison of estimated GFR and measured GFR in prospective living kidney donors.

    abstract:PURPOSE:The aim of this study was to examine the usefulness of three GFR-estimating equations (eGFR) compared with measured GFR (mGFR) in potential living kidney donors. METHODS:We compared the performance of the MDRD, CKD-Epi and Cockcroft-Gault equations with mGFR measured using (51)Cr-EDTA in 508 consecutive potent...

    journal_title:International urology and nephrology

    pub_type: 杂志文章

    doi:10.1007/s11255-014-0859-y

    authors: Bhuvanakrishna T,Blake GM,Hilton R,Burnapp L,Sibley-Allen C,Goldsmith D

    更新日期:2015-01-01 00:00:00

  • Juxtaglomerular cell tumor, causing fetal demise.

    abstract:AIMS:This case report describes juxtaglomerular cell tumor-a rare renin-producing tumor of the kidney, complicating pregnancy. CLINICAL CASE:A previously healthy 24-year-old primigravid woman developed hypertension in the 20th week of pregnancy, leading to a miscarriage in the 28th week. However, hypertension continue...

    journal_title:International urology and nephrology

    pub_type: 杂志文章

    doi:10.1007/s11255-010-9782-z

    authors: Lachvac L,Svajdler M,Valansky L,Nagy V,Benicky M,Frohlichova L,Nyitrayova O

    更新日期:2011-06-01 00:00:00

  • Application of amniotic membrane as xenograft for urethroplasty in rabbit.

    abstract:OBJECTIVES:Uroepithelium repair has always been the subject of discussion in urology surgeries. Using human amniotic membrane allograft has already proved to be useful in other fields. In this study, we use amniotic membrane to repair uroepithelium injuries in rabbits. METHODS:Twenty healthy rabbits underwent surgery ...

    journal_title:International urology and nephrology

    pub_type: 杂志文章

    doi:10.1007/s11255-009-9532-2

    authors: Shakeri S,Haghpanah A,Khezri A,Yazdani M,Monabbati A,Haghpanah S,Malekmakan L,Ayrempour S

    更新日期:2009-12-01 00:00:00

  • Iatrogenic reno-jejunal fistula.

    abstract::The development of a reno-jejunal fistula following a Roux-en-Y cystojejunostomy for an incorrectly diagnosed pancreatic pseudocyst is described. Up to now, this is the second case of iatrogenic reno-jejunal fistula reported in literature. Reno-jejunal fistulas are exceedingly rare and are usually consequences of urol...

    journal_title:International urology and nephrology

    pub_type: 杂志文章

    doi:10.1023/a:1007115605427

    authors: Aragona F,Norcen M,Battanello W,Oliva G

    更新日期:1999-01-01 00:00:00

  • Gonadal dysfunction and infertility in kidney transplant patients receiving sirolimus.

    abstract::Sirolimus is an immunosupressor of the mammalian target of rapamycin inhibitors (mTOR-I) group. Recent studies have emphasized a potential impact of sirolimus on male gonadal function. We report our clinical experience with sirolimus-induced gonadal dysfunction and infertility in both male and female kidney transplant...

    journal_title:International urology and nephrology

    pub_type: 杂志文章

    doi:10.1007/s11255-009-9644-8

    authors: Boobes Y,Bernieh B,Saadi H,Raafat Al Hakim M,Abouchacra S

    更新日期:2010-06-01 00:00:00

  • Expansion of bladder capacity by the use of intact sigmoid. An experimental study and two case reports.

    abstract::To enlarge bladder capacity after extensive segmental bladder resection, the authors sutered bladder margins to the serosal aspect of intact sigmoid (Heeg's method). Experimental data and two clinical cases have proved this technique to be of practical value. ...

    journal_title:International urology and nephrology

    pub_type: 杂志文章

    doi:10.1007/BF02082674

    authors: Proca E,Nicolescu D

    更新日期:1975-01-01 00:00:00

  • The vaginal influx and its significance in the diagnosis of infections of the urinary tract.

    abstract::The vaginal influx during miction is a frequent phenomenon. In our clinical study it showed a rate of 54 per cent. The significance of pathomorphological substrates is diminishing with the advancing vesical descensus. The posture during miction has but little influence on the vaginal deviation of the urinary stream. T...

    journal_title:International urology and nephrology

    pub_type: 杂志文章

    doi:10.1007/BF02086819

    authors: Engel D,Stobbe G,Schöne D

    更新日期:1979-01-01 00:00:00

  • A novel rat model of catheter-associated urinary tract infection.

    abstract:PURPOSE:The authors aimed to establish a rat model of catheter-associated UTIs using a complete urethral catheter. Bacterial growth in biofilms on urethral catheters was analyzed using standard culture methods to validate this model. METHODS:A total of 15 rats were divided into the following three groups according to ...

    journal_title:International urology and nephrology

    pub_type: 杂志文章

    doi:10.1007/s11255-015-1038-5

    authors: Kim HY,Choe HS,Lee DS,Yoo JM,Lee SJ

    更新日期:2015-08-01 00:00:00

  • Principles of quantitative water and electrolyte replacement of losses from osmotic diuresis.

    abstract::Osmotic diuresis results from urine loss of large amounts of solutes distributed either in total body water or in the extracellular compartment. Replacement solutions should reflect the volume and monovalent cation (sodium and potassium) content of the fluid lost. Whereas the volume of the solutions used to replace lo...

    journal_title:International urology and nephrology

    pub_type: 杂志文章,评审

    doi:10.1007/s11255-018-1822-0

    authors: Roumelioti ME,Ing TS,Rondon-Berrios H,Glew RH,Khitan ZJ,Sun Y,Malhotra D,Raj DS,Agaba EI,Murata GH,Shapiro JI,Tzamaloukas AH

    更新日期:2018-07-01 00:00:00

  • The prognostic value of proliferating cell nuclear antigen, Ki-67 and nucleolar organizer region in transitional cell carcinoma of the bladder.

    abstract:OBJECTIVES:To investigate the value of proliferating cell nuclear antigen (PCNA), Ki-67 antigen labelling indices and nucleolar organizer region (NOR) score in relation to histological grade, stage, recurrence and progression of the bladder tumor. MATERIALS AND METHODS:Tissue specimens from 77 bladder cancer patients ...

    journal_title:International urology and nephrology

    pub_type: 杂志文章

    doi:10.1023/a:1014452902976

    authors: Bozlu M,Orhan D,Baltaci S,Yaman O,Elhan AH,Tulunay O,Müftüoğlu YZ

    更新日期:2002-01-01 00:00:00

  • Therapeutic role of pelvic lymphadenectomy in carcinoma of the prostate: own experiences.

    abstract::Precise determination of the extent of lymph node involvement is of decisive importance for therapy of prostatic cancer. For this reason staging pelvic lymphadenectomy is fully indicated. Some authors expect from pelvic lymphadenectomy a therapeutic effect, too. The procedure is performed as a part of radical prostate...

    journal_title:International urology and nephrology

    pub_type: 杂志文章

    doi:10.1007/BF02549869

    authors: Morávek P

    更新日期:1987-01-01 00:00:00

  • The use of polytetrafluoroethylene (Gore-Tex) grafts in reconstruction of the urinary bladder.

    abstract::The safety and histopathologic effects of polytetrafluoroethylene (Gore-Tex) grafts in reconstruction of the urinary bladder were examined. Following partial excision of the bladder Gore-Tex was placed, and the rats were sacrificed at days 7, 14 and 30. Gore-Tex did not cause urine infection, and there was no peritoni...

    journal_title:International urology and nephrology

    pub_type: 杂志文章

    doi:10.1023/a:1007117917974

    authors: Senel FM,Akman RY,Arikan AY,Gürdal M,Can C

    更新日期:1999-01-01 00:00:00

  • A case of pyonephrosis secondary to ureteral stent calculus.

    abstract::Ureteric stents, a good solution to many urologic problems, can lead to significant morbidity if left in situ longer than required. Our case is that of an elderly male with a history of intractable hypertension presenting with urosepsis, anemia, diabetes and chronic renal failure. His work-up revealed a stent in the r...

    journal_title:International urology and nephrology

    pub_type: 杂志文章

    doi:10.1007/s11255-004-0021-3

    authors: Gopaldas R,Rastogi V,Gulick T

    更新日期:2005-01-01 00:00:00

  • Sexual dysfunction in type III chronic prostatitis (CP) and chronic pelvic pain syndrome (CPPS) observed in Turkish patients.

    abstract:AIM:Chronic prostatitis (CP) and chronic pelvic pain syndrome (CPPS) is a common disabling condition that is primarily associated with pain in the urogenital region and disturbances in urinary and sexual function. Chronic pelvic pain symptoms are the most common presentation, especially perineal, lower abdominal, testi...

    journal_title:International urology and nephrology

    pub_type: 杂志文章

    doi:10.1007/s11255-010-9809-5

    authors: Sönmez NC,Kiremit MC,Güney S,Arisan S,Akça O,Dalkılıç A

    更新日期:2011-06-01 00:00:00

  • Autoantibodies against phospholipase A2 receptor in Brazilian patients with glomerular diseases.

    abstract:BACKGROUND:Recently, great progress has been made in understanding the pathogenesis of membranous nephropathy (MN) with the discovery of autoantibodies (Abs) to M-type phospholipase A2 receptor (PLA2R) in serum and in immunocomplexes deposited in glomerulus in most adult patients with primary MN. OBJECTIVE:To evaluate...

    journal_title:International urology and nephrology

    pub_type: 杂志文章

    doi:10.1007/s11255-020-02682-w

    authors: Santos Neto CO,Passos MT,Fernandes DE,Nishida SK,Andrade LEC,Mastroianni Kirsztajn G

    更新日期:2020-10-31 00:00:00

  • Does chromophobe renal cell carcinoma have better survival than clear cell renal cell carcinoma? A clinical-based cohort study and meta-analysis.

    abstract:BACKGROUND:It is controversial whether chromophobe renal cell carcinoma (chRCC) or clear cell renal cell carcinoma (ccRCC) is associated with better survival. We conducted a clinical-based cohort study and meta-analysis to evaluate the prognostic role of histology between chRCC and ccRCC. METHODS:A cohort of 1540 pati...

    journal_title:International urology and nephrology

    pub_type: 杂志文章,meta分析,评审

    doi:10.1007/s11255-015-1161-3

    authors: Jiang HM,Wei JH,Zhang ZL,Fang Y,Zhou BF,Chen ZH,Lu J,Liao B,Zhou FJ,Luo JH,Chen W

    更新日期:2016-02-01 00:00:00

  • Asymptomatic spontaneous migration of double pigtail ureteral stent outside the ureter.

    abstract::We report a case of asymptomatic spontaneous migration outside the ureter of a double pigtail ureteral stent. This previously undescribed complication confirms the need for regular follow-up of patients with indwelling stents. ...

    journal_title:International urology and nephrology

    pub_type: 杂志文章

    doi:10.1007/s11255-005-4757-1

    authors: Cormio L,Piccinni R,Cafarelli A,Callea A,Zizzi V,Traficante A

    更新日期:2007-01-01 00:00:00

  • Side firing Neodymium:Yag laser prostatectomy: six years of experience with 170 patients.

    abstract:OBJECTIVES:To evaluate the results and complications in 170 patients with symptomatic benign hyperplasia who underwent laser prostatectomy focusing on six month and long-term results. METHODS:A total of 170 patients underwent side firing Neodymium:Yag laser prostatectomy between January 1995 and February 2001 of whom ...

    journal_title:International urology and nephrology

    pub_type: 杂志文章

    doi:10.1023/a:1025948028530

    authors: Metin A,Kayigil O,Ahmed SI

    更新日期:2003-01-01 00:00:00

  • Sodium-glucose cotransporter 2 inhibitors (SGLT2i): renal implications.

    abstract::Type 2 diabetes mellitus (DM2) is a chronic condition that affects more than 400 million individuals worldwide. In DM2 patients, an appropriate glycemic control slows the onset and delays the progression of all its micro and macrovascular complications. Even though there are several glucose-lowering drugs, only approx...

    journal_title:International urology and nephrology

    pub_type: 杂志文章,评审

    doi:10.1007/s11255-020-02585-w

    authors: Castañeda AM,Dutra-Rufato A,Juarez MJ,Grosembacher L,Gonzalez-Torres H,Musso CG

    更新日期:2020-08-07 00:00:00

  • Validity of urine neutrophile gelatinase-associated lipocalin in children with primary vesicoureteral reflux.

    abstract:BACKGROUND:Vesicoureteral reflux (VUR) is the most common congenital urinary tract abnormality in children. The objective of this study was to evaluate the diagnostic value of urine neutrophil gelatinase-associated lipocalin (NGAL) in children with primary vesicoureteral reflux (VUR). MATERIALS AND METHODS:A total of ...

    journal_title:International urology and nephrology

    pub_type: 杂志文章

    doi:10.1007/s11255-019-02355-3

    authors: Nickavar A,Valavi E,Safaeian B,Moosavian M

    更新日期:2020-04-01 00:00:00

  • Biochemical methods for the assessment of the selectivity of proteinuria.

    abstract::The authors have elaborated a biochemical technique for the assessment of the selectivity of proteinuria by means of the clearances of ceruloplasmin, haptoglobin and albumin. The results obtained in 69 patients were compared to those established by the method of Cameron and Blanford, as well as by the clearance of alp...

    journal_title:International urology and nephrology

    pub_type: 杂志文章

    doi:10.1007/BF02082033

    authors: Tishkov I,Razboynikov S,Tchoukanov C,Shipkova P

    更新日期:1978-01-01 00:00:00

  • The role of ureteroscopy as a diagnostic and therapeutic tool in various indications.

    abstract::Ureteroscopy is now in routine use for the diagnosis and treatment of various pathologies in the upper urinary tract. We report here on our experience in diagnostic and therapeutic applications of the 11.5 F rigid ureteroscope in 85 patients and 88 ureters. An overall success rate of 68.18% (60/88) was achieved when t...

    journal_title:International urology and nephrology

    pub_type: 杂志文章

    doi:10.1007/BF02767719

    authors: Ilker Y,Dillioğlugil O,Tarcan T,Türkeri L,Akdaş A

    更新日期:1994-01-01 00:00:00

  • Peritoneal clearances in scleroderma and diabetes mellitus: effects of intraperitioneal isoproterenol.

    abstract::Reduced peritoneal clearances of creatinine and urate were demonstrated repeatedly in a patient with scleroderma and a patient with diabetes mellitus. Urea clearances were not significantly different from usual values. The findings suggest decreased peritoneal membrane permeability and/or area (if urea clearance is fl...

    journal_title:International urology and nephrology

    pub_type: 杂志文章

    doi:10.1007/BF02082213

    authors: Nolph KD,Miller L,Husted FC,Hirszel P

    更新日期:1976-01-01 00:00:00

  • Efficacy of pentoxifylline in prevention of contrast-induced nephropathy in angioplasty patients.

    abstract:BACKGROUND:Contrast-induced nephropathy (CIN) is an adverse consequence of contrast media use that results in significant morbidity and mortality and adds significant costs to diagnostic and interventional cardiology procedures. Various pathophysiological mechanisms have been proposed for CIN and various agents have be...

    journal_title:International urology and nephrology

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s11255-011-0053-4

    authors: Firouzi A,Eshraghi A,Shakerian F,Sanati HR,Salehi N,Zahedmehr A,Kiani R,Madani M,Pedarzadeh A

    更新日期:2012-08-01 00:00:00

  • Evaluation of nutritional status with different methods in geriatric hemodialysis patients: impact of gender.

    abstract:PURPOSE:This study investigated the frequency of malnutrition in geriatric hemodialysis patients according to biochemical, anthropometric, bioelectrical impedance analysis (BIA), modified quantitative subjective global assessment (MQSGA), and geriatric nutritional risk index (GNRI) methods, and the effect of gender on ...

    journal_title:International urology and nephrology

    pub_type: 杂志文章

    doi:10.1007/s11255-014-0776-0

    authors: Kaya T,Sipahi S,Karacaer C,Nalbant A,Varım C,Cinemre H,Tamer A

    更新日期:2014-12-01 00:00:00

  • The association of congenital megaureter and ureteropelvic junction obstruction.

    abstract::Megaureter and ureteropelvic junction obstruction are not uncommon urinary tract congenital abnormalities. While each has been known to be associated with other urogenital anomalies, their association together is rarely reported. This report will describe the diagnosis and management of such a case. ...

    journal_title:International urology and nephrology

    pub_type: 杂志文章

    doi:10.1007/BF02083010

    authors: Waltzer WC

    更新日期:1983-01-01 00:00:00