Abstract:
:To clarify the relative importance of clinicopathological factors potentially affecting the survival of individuals initially diagnosed as having metastatic renal cell carcinoma (RCC), univariate and multivariate analyses using Cox's proportional hazards model were performed for 111 RCC patients who were admitted to four hospitals in Nagoya, Japan, between 1978 and 1993. Survival time was calculated from the date of diagnosis to the date of death or the end of May, 1995. Nineteen factors (17 clinically applicable before treatment and 2 histological in nature) were included for assessment. Univariate analysis revealed that 10 of the total 19 factors were significantly associated with patient survival. Multivariate analysis found 7 factors to be statistically significant determinants. Survival was further evaluated by categorizing the patients into three groups according to the number of the 7 factors. These groups showed clearly different survivals (log-rank test, p < 0.0001), confirming the importance of the 7 factors as definite determinants. They should therefore prove to be of advantage for classifying metastatic RCC patients when designing clinical prospective studies of immunotherapy and chemotherapy.
journal_name
Int Urol Nephroljournal_title
International urology and nephrologyauthors
Takashi M,Kawai T,Murase T,Wakai K,Ohno Ydoi
10.1007/BF02550925subject
Has Abstractpub_date
1997-01-01 00:00:00pages
291-300issue
3eissn
0301-1623issn
1573-2584journal_volume
29pub_type
杂志文章abstract::Cyproterone acetate was given as monotherapy to 18 patients with advanced prostatic carcinoma at a weekly dose of 300 mg. Progression was observed in all of the patients; median time to progression was 35 months and median survival time was 48 months. Partial response, stabilization, progression and exitus rates by ye...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02551344
更新日期:1997-01-01 00:00:00
abstract::Aluminum transfer and dialysance during haemodialysis and plasma aluminum concentrations in haemodialysis patients were examined. Plasma aluminum in 30 volunteer outpatients tended to decrease after 5-hour dialysis (6.35 +/- 3.02 micrograms/dl before haemodialysis; 5.41 +/- 2.60 micrograms/dl after haemodialysis). The...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02583037
更新日期:1988-01-01 00:00:00
abstract::Posterior urethral valves are usually detected during infancy by prenatal sonography. Less is known about presentation and outcome in older patients. We are describing a patient who presented with renal stones and was found incidentally on cystoscopy to have Type I urethral valves. ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1023/b:urol.0000020294.84579.a4
更新日期:2003-01-01 00:00:00
abstract:PURPOSE:Non-adherence (NA) to medication is a major contributor to treatment failure in hypertensive patients. Factors of the ecological model, at family/healthcare professional, service, and system levels, are rarely evaluated as correlates of NA in hypertensive patients. METHODS:This crossectional study assessed the...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-020-02755-w
更新日期:2021-01-16 00:00:00
abstract:OBJECTIVE:Hemodialysis (HD) patients are at risk of deficiency of essential trace elements and excess of toxic trace elements. The aim of the study was to evaluate the relation between the serum levels of some trace elements and heavy metals (iron, zinc, manganese, copper, magnesium, cobalt, cadmium, and lead) and endo...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-011-0055-2
更新日期:2012-10-01 00:00:00
abstract:PURPOSE:The impact of radical surgery for urothelial carcinoma is significant on patient's quality of life. Organ-sparing surgery (OSS) can provide comparable oncological outcomes and with improved quality of life. In this review, we summarize the indications, techniques and outcomes of OSS for these tumors. METHODS:P...
journal_title:International urology and nephrology
pub_type: 杂志文章,评审
doi:10.1007/s11255-019-02232-z
更新日期:2019-11-01 00:00:00
abstract::Ganglioneuroblastoma is a common type of tumor in children, but is rarely seen in adults. We present here a case of adrenal ganglioneuroblastoma in a 59-year old man. ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-004-0851-z
更新日期:2004-01-01 00:00:00
abstract::Eighty-four patients with testicular seminoma were treated at the Northern Israel Oncology Center during the years 1968-1988. Using the staging classification of Hussey, 69 patients (82%) had Stage I, eight (10%) had Stage IIA, four (5%) had Stage IIB, one (1%) had Stage IIIA, and two (2%) had Stage IIIB disease. Sixt...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02768019
更新日期:1994-01-01 00:00:00
abstract:PURPOSE:Cognitive dysfunction (CO/DY) in chronic kidney disease (CKD) patients has long been recognized. Hypertension is also associated with CO/DY. The study describes associated factors with CO/DY in CKD patients compared to hypertensive subjects. METHODS:Ninety-six hypertensive subjects without CKD, 19 patients wit...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-013-0450-y
更新日期:2013-12-01 00:00:00
abstract:BACKGROUND:HAAKI is a common clinical problem in hospitalized patients. Its incidence is high in older patients and carries worse prognosis. The presence of multiple co-morbidities, aging process, and frequent diagnostic and therapeutic interventions predispose elderly patients to HAAKI. This study aims to evaluate the...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-019-02130-4
更新日期:2019-05-01 00:00:00
abstract:BACKGROUND:Patients with chronic kidney disease mineral and bone disorders (CKD-MBD) suffer high rates of morbidity and mortality, in particular related to bone and cardiovascular outcomes. The management of CKD-MBD remains challenging. The objective of this systematic survey is to critically appraise clinical practice...
journal_title:International urology and nephrology
pub_type: 杂志文章,评审
doi:10.1007/s11255-016-1436-3
更新日期:2017-02-01 00:00:00
abstract::To evaluate cancer involvement of internal female genitalia of patients undergoing anterior exenteration for clinically organ confined transitional cell carcinoma of the bladder, and identify potential preoperative risk factors. Charts and anterior exenteration specimens from 54 women with clinically organ confined tr...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-006-9158-6
更新日期:2007-01-01 00:00:00
abstract:PURPOSE:Sleep disturbance is significantly associated with overall morbidity, mortality, and quality of life in end-stage renal disease patients. Although it was reported that the prevalence of poor sleep quality was 41-83% in hemodialysis patients, sleep disturbance was not well understood in peritoneal dialysis (PD) ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-011-0060-5
更新日期:2012-06-01 00:00:00
abstract::Multiple myeloma is characterized by marrow plamacytsois, M spike in serum or urine electrophoresis and skeletal lytic lesions. The M spike may be absent in rare instances. We describe a case of myeloma cast nephropathy with acute renal failure who did not exhibit an M spike. lambda-chain staining was documented on im...
journal_title:International urology and nephrology
pub_type: 杂志文章,评审
doi:10.1007/s11255-004-2362-3
更新日期:2005-01-01 00:00:00
abstract:AIM:To determine the effectiveness of transdermal electromotive administration (TEA) of verapamil and dexamethasone in the treatment of Peyronie's disease (PD). METHOD:Totally, 51 patients with PD were prospectively included in the study. All patients were evaluated by history, subjective score scales, physical examin...
journal_title:International urology and nephrology
pub_type: 临床试验,杂志文章
doi:10.1007/s11255-008-9408-x
更新日期:2009-01-01 00:00:00
abstract::Twenty-six boys were evaluated and treated for posterior urethral valves. At the time the valves were diagnosed unilateral or bilateral vesicoureteral reflux was present in 58% of the ureters and 69% of the children, while dilatation of the upper urinary tract was present in 88% and 92%, respectively. There was a vari...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02549902
更新日期:1989-01-01 00:00:00
abstract:AIM:To evaluate the infectious complications, microorganism distribution and antibacterial treatment in patients who underwent percutaneous nephrolithotomy (PCNL). PATIENTS AND METHODS:Three hundred and thirty-eight patients who were 17 years age or older who underwent PCNL between January 2001 and December 2002 have ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-006-9147-9
更新日期:2007-01-01 00:00:00
abstract:INTRODUCTION:Renal physiology is a partially cyclooxygenase (COX)-dependent system. Kidneys express both COX-1 and COX-2 enzymes. In this study, we tried to investigate the effects of diclofenac sodium (D), with or without furosemide (F), on plasma renin activity (PRA), serum and urine electrolytes, creatinine clearanc...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-008-9496-7
更新日期:2009-12-01 00:00:00
abstract::In this study we explored the possible role of arachidonoylethanolamine (AEA) in regulating blood pressure in patients on continuous ambulatory peritoneal dialysis (CAPD). One hundred and five patients on CAPD were enrolled. Volume status was evaluated by the overhydration (OH) value obtained by bioimpedance analysis....
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-012-0153-9
更新日期:2012-12-01 00:00:00
abstract::Kidney injury molecule-1 (KIM-1) staining has been shown to be very useful in identifying acute proximal tubular injury, but its sensitivity, specificity and predicting values for the recovery of renal function after injury in renal biopsies have not been well established. In the first study, we randomly selected 184 ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-019-02311-1
更新日期:2019-12-01 00:00:00
abstract:OBJECTIVE:We describe a new technique that can easily be used as a tension-free practical alternative in closing the renal defects resulting after open partial nephrectomy (PN). METHODS:A new technique (called "lipocorticoplasty") where "wrapped fatty tissue" was placed in the tumor crater to close the renal defects t...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-011-9899-8
更新日期:2011-09-01 00:00:00
abstract:OBJECTIVES:Anastomotic stricture (AS) is a well-described complication of radical retropubic prostatectomy (RRP) despite all the refinements in surgical technique. We aimed to define and discuss the role of postoperative urinary drainage on AS development. PATIENTS AND METHODS:A total of 136 patients with localized pr...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-007-9309-4
更新日期:2008-01-01 00:00:00
abstract::A 67-year-old Saudi man with poorly controlled diabetes-mellitus underwent orchiectomy for a painful left testicular swelling that did not respond to antibiotics. Clinical diagnosis was testicular malignancy. Histologic workup demonstrated extensive involvement of the testis and epididymis by diffuse infiltrate of lar...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-009-9674-2
更新日期:2010-09-01 00:00:00
abstract::Renal blood flow measurements have been carried out by means of positron emission tomography (PET) to facilitate the detection of radiation-induced injuries. The advantages of the method employed in animal experiments are described. ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02550121
更新日期:1992-01-01 00:00:00
abstract:OBJECTIVES:To evaluate the association between preoperative detrusor underactivity (DU) and symptomatic bladder neck contracture (BNC) in patients undergoing radical retropubic prostatectomy (RRP), in order to identify a possible new risk factor in the etiopathogenic mechanisms of BNC after RRP. METHODS:A total of 100...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-013-0426-y
更新日期:2013-06-01 00:00:00
abstract::Sex cord stromal tumors are rare and account for approximately 6% of all testicular neoplasms. We report a case of sex cord tumor composed of granulosa cells and Sertoli cells in the adult testis. ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1023/b:urol.0000022907.66796.61
更新日期:2003-01-01 00:00:00
abstract::High Grade Prostatic Intraepithelial Neoplasia (HGPIN) has been recognized as the most likely precursor of invasive carcinoma of the prostate. Close surveillance and follow-up are indicated if subsequent procedures fail to identify carcinoma. There is still considerable controversy about the natural history of high gr...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1023/a:1020504832002
更新日期:2001-01-01 00:00:00
abstract:PURPOSE:The present study aimed at evaluating the relationship between Klotho levels and insulin resistance and albumin-to-creatinine ratio (ACR) in type 2 diabetic patients with CKD. METHODS:We conducted an observational, cross-sectional study in our outpatient diabetic nephropathy clinic from 2014 to 2016, enrolling...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-017-1646-3
更新日期:2017-10-01 00:00:00
abstract:BACKGROUND:Recently, there have been a few reports on the decrease in the incidence of severe Henoch-Schönlein purpura nephritis (HSPN) in Japan. To evaluate the incidence and the severity of HSPN, we examined the epidemiology and clinical manifestations of HSPN in Fukushima Prefecture over a 22-year period. METHODS:W...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-009-9701-3
更新日期:2010-12-01 00:00:00
abstract::Crossed renal ectopia and/or asymmetric fused kidney are unusual congenital anomalies. The deformity itself usually produces no symptoms and the clinical presentation generally suggests obstruction and infection. In our series, 10 of 11 patients presented with various vertebral anomalies. A theory of embryogenesis was...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02549675
更新日期:1987-01-01 00:00:00