当前位置： SCI文献检索 > INTERNATIONAL UROLOGY AND NEPHROLOGY期刊下所有文献 > Renal function and urine drainage after conservative or operative treatment of primary (obstructive) megaureter in infants and children.

Renal function and urine drainage after conservative or operative treatment of primary (obstructive) megaureter in infants and children.

Abstract：

UNLABELLED:We examined renal function and urinary drainage of children with primary megaureter (PMU) in dependence on conservative or operative treatment. MATERIAL AND METHODS:The retrospective analysis covering the years 1994 to 2000 comprised children at an age of 0-7 years with 35 PMU. Sonography, dynamic MAG3 renography as well as endogenic creatinine clearance (GFR) were used to assess drainage and the renal function. Temporary urinary diversion was established in fourteen patients of both groups. In 14 children with 16 PMU a ureteroneocystostomy (UNC) was performed. The average observation period was 30 months (11-108). RESULTS:The children of the UNC group differed from the non-neoimplanted group in the age at diagnosis (10.5 vs. < 1 months), higher degrees of hydronephrosis on average, a more distinct dilatation of the ureter as well as renographically significant obstruction. Children of the non-UNC group, including four children with a type B drainage curve (O'Reilly), had an unimpaired differential renal function or improved during the observation period (initially 51% vs. 50.5% at the end). In neoimplantation group the differential function improved from 32.5% to 38.5% (p < 0.05) and obstruction resolved with one exception. CONCLUSION:Given a higher-grade PMU with a reduced function of the kidneys and a significant impaired drainage pattern and/or symptoms, neoimplantation without temporary diversion has proved to be an efficient renoprotective method. Furthermore, data clearly justify a conservative approach without urinary diversion in infants with large asymptomatic PMU.

journal_name

Int Urol Nephrol

journal_title

International urology and nephrology

authors

Tröbs RB,Heinecke K,Elouahidi T,Nounla J,Kluge R

doi

10.1007/s11255-005-3615-5

keywords:

subject

Has Abstract

pub_date

2006-01-01 00:00:00

pages

141-7

issue

1

eissn

0301-1623

issn

1573-2584

journal_volume

38

pub_type

杂志文章

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