Author Correction: Multicellular 3D Neurovascular Unit Model for Assessing Hypoxia and Neuroinflammation Induced Blood-Brain Barrier Dysfunction.

abstract：:Development of artificial materials for the facilitation of cartilage regeneration remains an important challenge in orthopedic practice. Our study investigates the potential for neocartilage formation within a synthetic polyester scaffold based on the polymerization of high internal phase emulsions. The fabrication o...

journal_title：Scientific reports

authors： Naranda J,Sušec M,Maver U,Gradišnik L,Gorenjak M,Vukasović A,Ivković A,Rupnik MS,Vogrin M,Krajnc P

更新日期：2016-06-24 00:00:00

abstract：:The temporal dynamics of brain activation during visual and auditory perception of congruent vs. incongruent musical video clips was investigated in 12 musicians from the Milan Conservatory of music and 12 controls. 368 videos of a clarinetist and a violinist playing the same score with their instruments were presente...

journal_title：Scientific reports

authors： Proverbio AM,Calbi M,Manfredi M,Zani A

更新日期：2014-07-29 00:00:00

abstract：:During nervous system development growing axons can interact with each other, for example by adhering together in order to produce bundles (fasciculation). How does such axon-axon interaction affect the resulting axonal trajectories, and what are the possible benefits of this process in terms of network function? In t...

journal_title：Scientific reports

authors： Davis O,Merrison-Hort R,Soffe SR,Borisyuk R

更新日期：2017-10-19 00:00:00

abstract：:Treatment as Prevention (TasP) using directly-acting antivirals has been advocated for Hepatitis C Virus (HCV) in people who inject drugs (PWID), but treatment is expensive and TasP's effectiveness is uncertain. Previous modelling has assumed a homogeneously-mixed population or a static network lacking turnover in the...

journal_title：Scientific reports

authors： Metzig C,Surey J,Francis M,Conneely J,Abubakar I,White PJ

更新日期：2017-05-12 00:00:00

abstract：:The aim of this study was to estimate substitution rate and imprints of natural selection on parvovirus B19 genotype 1. Studied datasets included 137 near complete coding B19 genomes (positions 665 to 4851) for phylogenetic and substitution rate analysis and 146 and 214 partial genomes for selection analyses in open r...

journal_title：Scientific reports

authors： Stamenković GG,Ćirković VS,Šiljić MM,Blagojević JV,Knežević AM,Joksić ID,Stanojević MP

更新日期：2016-10-24 00:00:00

abstract：:Recently, a concept of digital metamaterials has been proposed to manipulate field distribution through proper spatial mixtures of digital metamaterial bits. Here, we present a design of 2-bit digitally-controlled coding metasurface that can effectively modulate the scattered electromagnetic wave and realize different...

journal_title：Scientific reports

authors： Huang C,Sun B,Pan W,Cui J,Wu X,Luo X

更新日期：2017-02-08 00:00:00

abstract：:The use of anti-cancer adjuvant therapy is rationalized by potentiating the efficacy, and/or protecting from major side effects of chemotherapeutics. Thymoquinone (TQ) is a naturally occurring compound with cumulative evidence of anti-cancer properties. In this study, we assessed the chemomodulatory potential of TQ to...

journal_title：Scientific reports

authors： Bashmail HA,Alamoudi AA,Noorwali A,Hegazy GA,AJabnoor G,Choudhry H,Al-Abd AM

更新日期：2018-08-03 00:00:00

abstract：:Hydrocarbons fuel our economy. Furthermore, intermediate goods and consumer products are often hydrocarbon-based. Beside all the progress they made possible, hydrogen-containing substances can have severe detrimental effects on materials exposed to them. Hydrogen-assisted failure of iron alloys has been recognised mor...

journal_title：Scientific reports

authors： Röhsler A,Sobol O,Hänninen H,Böllinghaus T

更新日期：2020-02-27 00:00:00

abstract：:The combination of genome-edited human embryonic stem cells (hESCs) and subsequent neural differentiation is a powerful tool to study neurodevelopmental disorders. Since the naïve state of pluripotency has favourable characteristics for efficient genome-editing, we optimized a workflow for the CRISPR/Cas9 system in th...

journal_title：Scientific reports

authors： Jacobs EZ,Warrier S,Volders PJ,D'haene E,Van Lombergen E,Vantomme L,Van der Jeught M,Heindryckx B,Menten B,Vergult S

更新日期：2017-11-30 00:00:00

abstract：:This study aimed to identify single nucleotide polymorphisms (SNPs) associated with milk cholesterol (CHL) content via a genome wide association study (GWAS). Milk CHL content was determined by gas chromatography and expressed as mg of CHL in 100 g of fat (CHL_fat) or in 100 mg of milk (CHL_milk). GWAS was performed w...

journal_title：Scientific reports

authors： Do DN,Schenkel FS,Miglior F,Zhao X,Ibeagha-Awemu EM

更新日期：2018-09-05 00:00:00

abstract：:Nanocarrier systems for the encapsulation of agrochemicals can contribute to sustainable agriculture, but few nanosystems have been developed for plant growth regulators (PGRs). The present study evaluated the effects of seed priming using alginate/chitosan (nanoALG/CS) and chitosan/tripolyphosphate (nanoCS/TPP) conta...

journal_title：Scientific reports

authors： Pereira ADES,Oliveira HC,Fraceto LF

更新日期：2019-05-09 00:00:00

abstract：:The hair bundle of cochlear hair cells is the site of auditory mechanoelectrical transduction. It is formed by three rows of stiff microvilli-like protrusions of graduated heights, the short, middle-sized, and tall stereocilia. In developing and mature sensory hair cells, stereocilia are connected to each other by var...

journal_title：Scientific reports

authors： Michel V,Pepermans E,Boutet de Monvel J,England P,Nouaille S,Aghaie A,Delhommel F,Wolff N,Perfettini I,Hardelin JP,Petit C,Bahloul A

更新日期：2020-10-02 00:00:00

abstract：:We report two brothers from a non-consanguineous Irish family presenting with a novel syndrome characterised by intellectual disability, facial dysmorphism, scoliosis and long QT. Their mother has a milder phenotype including long QT. X-linked inheritance was suspected. Whole exome sequencing identified a novel missen...

journal_title：Scientific reports

authors： Casey JP,Støve SI,McGorrian C,Galvin J,Blenski M,Dunne A,Ennis S,Brett F,King MD,Arnesen T,Lynch SA

更新日期：2015-11-02 00:00:00

abstract：:Development of new antimicrobial agents is required against the causative agent for listeriosis, Listeria monocytogenes, as the number of drug resistant strains continues to increase. A promising target is the β-ketoacyl-acyl carrier protein synthase FabF, which participates in the catalysis of fatty acid synthesis an...

journal_title：Scientific reports

authors： Soares da Costa TP,Nanson JD,Forwood JK

更新日期：2017-01-03 00:00:00

abstract：:Systemic lupus erythematosus (SLE) features a decreased pool of CD4+CD25+Foxp3+ T regulatory (Treg) cells. We had previously observed NKG2D+CD4+ T cell expansion in contrast to a decreased pool of Treg cells in SLE patients, but whether NKG2D+CD4+ T cells contribute to the decreased Treg cells remains unclear. In the ...

journal_title：Scientific reports

authors： Yang D,Tian Z,Zhang M,Yang W,Tang J,Wu Y,Ni B

更新日期：2017-04-28 00:00:00

abstract：:A major translational challenge in the fields of therapeutic angiogenesis and regenerative medicine is the need to create functional microvasculature. The purpose of this study was to assess whether a potentially autologous endothelial cell (EC) source derived from human induced pluripotent stem cells (iPSC-ECs) can f...

journal_title：Scientific reports

authors： Bezenah JR,Kong YP,Putnam AJ

更新日期：2018-02-08 00:00:00

abstract：:In this work, surface plasmons (SPs) on a germanium (Ge) thin film in terahertz (THz) region that are excited by electron cyclotron motion (ECM) and the subsequent SP emission (SPE) by adding Ge gratings on the film are explored by finite-difference time-domain (FDTD) and particle-in-cell FDTD (PIC-FDTD) simulations. ...

journal_title：Scientific reports

authors： Lan YC,Shen CH,Chen CM

更新日期：2020-10-07 00:00:00

abstract：:A novel type of transparent monitor with high-resolution images based on Si-SiO2 core-shell nanoparticles is presented in this contribution. In this monitor, a quasi-array of nanoparticles was used to obtain a very sharp scattering profile. For this purpose, the Si-SiO2 nanoparticles were synthesized and with controll...

journal_title：Scientific reports

authors： Dolatyari M,Jafari A,Rostami A,Klein A

更新日期：2019-02-19 00:00:00

abstract：:The pollination syndrome concept has provided powerful utility in understanding the evolution and adaptation of floral traits. However, the utility of this conception has been questioned on the grounds that flowers usually attract a broader spectrum of visitors than one might expect. Furthermore, the relationship betw...

journal_title：Scientific reports

authors： Wang X,Wen M,Qian X,Pei N,Zhang D

更新日期：2020-08-18 00:00:00

abstract：:At mid-ocean ridges volcanism generally decreases with spreading rate but surprisingly massive volcanic centres occur at the slowest spreading ridges. These volcanoes can host unexpectedly strong earthquakes and vigorous, explosive submarine eruptions. Our understanding of the geodynamic processes forming these volcan...

journal_title：Scientific reports

authors： Schmid F,Schlindwein V,Koulakov I,Plötz A,Scholz JR

更新日期：2017-02-20 00:00:00

abstract：:Downstream analysis of genomic and transcriptomic sequence data is often executed by functional annotation that can be performed by various bioinformatics tools and biological databases. However, a full fast integrated tool is not available for such analysis. Besides, the current available software is not able to prod...

journal_title：Scientific reports

authors： Araujo FA,Barh D,Silva A,Guimarães L,Ramos RTJ

更新日期：2018-01-29 00:00:00

abstract：:Nonequilibrium can be a source of order. This rather counterintuitive statement has been proven to be true through a variety of fluctuation-driven, self-organization behaviors exhibited by out-of-equilibrium, many-body systems in nature (physical, chemical, and biological), resulting in the spontaneous appearance of m...

journal_title：Scientific reports

authors： Kim JH,Noe GT 2nd,McGill SA,Wang Y,Wójcik AK,Belyanin AA,Kono J

更新日期：2013-11-21 00:00:00

abstract：:Platelet transfusions can cause adverse reactions in their recipients, including transfusion-related acute lung injury (TRALI). The pathophysiology of TRALI depends on a number of signaling pathways and the inflammatory role played by blood platelets remains controversial. Platelets are important in inflammation, part...

journal_title：Scientific reports

authors： Tariket S,Hamzeh-Cognasse H,Laradi S,Arthaud CA,Eyraud MA,Bourlet T,Berthelot P,Garraud O,Cognasse F

更新日期：2019-08-29 00:00:00

abstract：:The psychrophilic (cold-loving) fungus Pseudogymnoascus destructans was discovered more than a decade ago to be the pathogen responsible for white-nose syndrome, an emerging disease of North American bats causing unprecedented population declines. The same species of fungus is found in Europe but without associated mo...

journal_title：Scientific reports

authors： Ren P,Rajkumar SS,Zhang T,Sui H,Masters PS,Martinkova N,Kubátová A,Pikula J,Chaturvedi S,Chaturvedi V

更新日期：2020-08-17 00:00:00

abstract：:Over the last decades, great strides were made in the development of novel implants for the treatment of bone defects. The increasing versatility and complexity of these implant designs request for concurrent advances in means to assess in vivo the course of induced bone formation in preclinical models. Since its disc...

journal_title：Scientific reports

authors： Lienemann PS,Metzger S,Kiveliö AS,Blanc A,Papageorgiou P,Astolfo A,Pinzer BR,Cinelli P,Weber FE,Schibli R,Béhé M,Ehrbar M

更新日期：2015-05-19 00:00:00

abstract：:The natural alkaloid berberine has several pharmacological properties and recently received attention as a potential anticancer agent. In this work, we investigated the molecular mechanisms underlying the anti-tumor effect of berberine on glioblastoma U343 and pancreatic carcinoma MIA PaCa-2 cells. Human dermal fibrob...

journal_title：Scientific reports

authors： Agnarelli A,Natali M,Garcia-Gil M,Pesi R,Tozzi MG,Ippolito C,Bernardini N,Vignali R,Batistoni R,Bianucci AM,Marracci S

更新日期：2018-07-13 00:00:00

abstract：:The annotation of protein function is a vital step to elucidate the essence of life at a molecular level, and it is also meritorious in biomedical and pharmaceutical industry. Developments of sequencing technology result in constant expansion of the gap between the number of the known sequences and their functions. Th...

journal_title：Scientific reports

authors： Li Z,Liu Z,Zhong W,Huang M,Wu N,Xie Y,Dai Z,Zou X

更新日期：2016-11-16 00:00:00

abstract：:Outbreaks involving the Asian genotype Chikungunya virus (CHIKV) caused over one million infections in the Americas recently. The outbreak was preceded by a major nationwide outbreak in the Philippines. We examined the phylogenetic and phylogeographic relationships of representative CHIKV isolates obtained from the 20...

journal_title：Scientific reports

authors： Tan KK,Sy AK,Tandoc AO,Khoo JJ,Sulaiman S,Chang LY,AbuBakar S

更新日期：2015-07-23 00:00:00

abstract：:Microorganisms in vertebrate guts have been recognized as important symbionts influencing host life. However, it remains unclear about the gut microbiota in long-distance migratory Anseriformes herbivores, which could be functionally important for these wetland-dependent animals. We collected faeces of the greater whi...

journal_title：Scientific reports

authors： Yang Y,Deng Y,Cao L

更新日期：2016-09-07 00:00:00

abstract：:Robust biomarker quantification is essential for the accurate diagnosis of diseases and is of great value in cancer management. In this paper, an innovative diagnostic platform is presented which provides automated molecularly imprinted solid-phase extraction (MISPE) followed by liquid chromatography-mass spectrometry...

journal_title：Scientific reports

authors： Rossetti C,Świtnicka-Plak MA,Grønhaug Halvorsen T,Cormack PA,Sellergren B,Reubsaet L

更新日期：2017-03-17 00:00:00