Modulation of non-bilayer lipid phases and the structure and functions of thylakoid membranes: effects on the water-soluble enzyme violaxanthin de-epoxidase.

abstract：:Somatic mutations of many cancer genes tend to co-occur (termed co-mutations) in certain patterns during tumor initiation and progression. However, the genetic and epigenetic mechanisms that contribute to the co-mutations of these cancer genes have yet to be explored. Here, we systematically investigated the associati...

journal_title：Scientific reports

authors： Shi Y,Su XB,He KY,Wu BH,Zhang BY,Han ZG

更新日期：2016-10-20 00:00:00

abstract：:Clostridium difficile is a gastrointestinal pathogen but how the bacterium colonises this niche is still little understood. Sortase enzymes covalently attach specific bacterial proteins to the peptidoglycan cell wall and are often involved in colonisation by pathogens. Here we show C. difficile proteins CD2537 and CD3...

journal_title：Scientific reports

authors： Peltier J,Shaw HA,Wren BW,Fairweather NF

更新日期：2017-08-23 00:00:00

abstract：:PC4, a well-known general transcription cofactor, has multiple functions in transcription and DNA repair. Residue W89, is engaged in stacking interactions with DNA in PC4, but substituted by tyrosine in some PC4 orthologous proteins. In order to understand the consequences and reveal the molecular details of this subs...

journal_title：Scientific reports

authors： Huang J,Zhao Y,Liu H,Huang D,Cheng X,Zhao W,Taylor IA,Liu J,Peng YL

更新日期：2015-03-05 00:00:00

abstract：:Thermal management and simulation are becoming increasingly important in many areas of engineering applications. There are three cooling routes for thermal management, namely thermal conduction, thermal convection and thermal radiation, among which the first two approaches have been widely studied and applied, while t...

journal_title：Scientific reports

authors： Zhang HH,Sha WEI,Huang ZX,Shi GM

更新日期：2018-02-08 00:00:00

abstract：:We investigate recovery of multispecies oral biofilms following chlorhexidine gluconate (CHX) and CHX with surface modifiers (CHX-Plus) treatment. Specifically, we examine the percentage of viable bacteria in the biofilms following their exposure to CHX and CHX-Plus for 1, 3, and 10 minutes, respectively. Before antim...

journal_title：Scientific reports

authors： Shen Y,Zhao J,de la Fuente-Núñez C,Wang Z,Hancock RE,Roberts CR,Ma J,Li J,Haapasalo M,Wang Q

更新日期：2016-06-21 00:00:00

abstract：:Ultrasound has significantly increased safety and effectiveness in regional anesthesia. However, little is known about its clinical use. We studied clinical approaches currently used by anesthesiologists, conducted a nationwide survey, and analyzed data collected in ordered logistic regression models. All active membe...

journal_title：Scientific reports

authors： Luedi MM,Upadek V,Vogt AP,Steinfeldt T,Eichenberger U,Sauter AR

更新日期：2019-06-24 00:00:00

abstract：:Loss-of-function mutations in TREM2 cause Nasu-Hakola disease (NHD), a rare genetic disease characterized by early-onset dementia with leukoencephalopathy and bone cysts. An NHD-associated mutation, c.482 + 2 T > C, disrupts the splice donor site of intron 3 and causes aberrant skipping of exon 3, resulting in the los...

journal_title：Scientific reports

authors： Yanaizu M,Sakai K,Tosaki Y,Kino Y,Satoh JI

更新日期：2018-05-02 00:00:00

abstract：:For infants with acute progressive hydrocephalus, invasive drainage of cerebrospinal fluid (CSF) is performed until a ventriculo-peritoneal shunt can be inserted. Surrogate markers of intracranial pressure (ICP) may help optimise the timing of invasive procedures. To assess whether RI with/without fontanel compression...

journal_title：Scientific reports

authors： Yoshizuka T,Kinoshita M,Iwata S,Tsuda K,Kato T,Saikusa M,Shindou R,Hara N,Harada E,Takashima S,Takeshige N,Saitoh S,Yamashita Y,Iwata O

更新日期：2018-08-07 00:00:00

abstract：:Glomerular filtration rate (GFR) assessment is indicated before every administration of cisplatin. The optimal modality for this purpose [GFR measurement by urinary Creatinine Clearance (uCrCl) versus GFR estimation (eGFR) by the CKD-EPI formula versus both] is unclear. We investigated whether eGFR only is safe in thi...

journal_title：Scientific reports

authors： Klöckl MC,Kasparek AK,Riedl JM,Moik F,Mollnar S,Stotz M,Szkandera J,Terbuch A,Gerger A,Niedrist T,Pichler M,Bauernhofer T,Schilcher G,Zitta S,Rosenkranz AR,Friedl C,Stöger H,Posch F

更新日期：2020-07-08 00:00:00

abstract：:Mammalian sperm are unable to fertilize the egg immediately after ejaculation. To gain fertilization competence, they need to undergo a series of modifications inside the female reproductive tract, known as capacitation. Capacitation involves several molecular events such as phosphorylation cascades, hyperpolarization...

journal_title：Scientific reports

authors： Ritagliati C,Luque GM,Stival C,Baro Graf C,Buffone MG,Krapf D

更新日期：2018-09-06 00:00:00

abstract：:The ejection of internal organs, i.e., evisceration, is a well-known phenomenon in sea-cucumbers. We report the ability of a member of the Chordate phyla, the tropical ascidian Polycarpa mytiligera, to eviscerate and regenerate its gut within 12 days, and to rebuild its branchial sac within 19 days. Evisceration occur...

journal_title：Scientific reports

authors： Shenkar N,Gordon T

更新日期：2015-04-16 00:00:00

abstract：:Wet-chemistry methods have crucial advantages for the synthesis of nanostructures, including simple, low-cost, large-area, and low-temperature deposition on almost arbitrary substrates. Nevertheless, the rational design of improved wet-chemistry procedures is extremely difficult because, in practice, only post-synthes...

journal_title：Scientific reports

authors： Orsini A,Falconi C

更新日期：2014-09-05 00:00:00

abstract：:It is shown that in the ergodic regime, the temperature dependence of Young's modulus is solely determined by the magnetic properties of a material. For the large class of materials with paramagnetic or diamagnetic response, simple functional forms of the temperature derivative of Young's modulus are derived and compa...

journal_title：Scientific reports

authors： Binek C

更新日期：2017-07-07 00:00:00

abstract：:The photo-reduction of metal ions in solution induced by femtosecond laser is an important and novel method for fabricating three-dimensional metal microstructures. However, the nonlinear absorption cross section of metal ions remains unknown because its measurement is difficult. In the present study, a method based o...

journal_title：Scientific reports

authors： Ma ZC,Chen QD,Han B,Liu XQ,Song JF,Sun HB

更新日期：2015-12-11 00:00:00

abstract：:Similar to sleeping after learning, a brief period of wakeful resting after encoding new information supports memory retention in contrast to task-related cognition. Recent evidence suggests that working memory capacity (WMC) is related to sleep-dependent declarative memory consolidation. We tested whether WMC moderat...

journal_title：Scientific reports

authors： Martini M,Marhenke R,Martini C,Rossi S,Sachse P

更新日期：2020-10-21 00:00:00

abstract：:Reversible phosphorylation of proteins and the assembly of thylakoid complexes are the important protective mechanism against environmental stresses in plants. This research was aimed to investigate the different responses of the antioxidant defense system and photosystem II (PSII) to osmotic stress between drought-re...

journal_title：Scientific reports

authors： Chen YE,Cui JM,Su YQ,Zhang CM,Ma J,Zhang ZW,Yuan M,Liu WJ,Zhang HY,Yuan S

更新日期：2017-10-05 00:00:00

abstract：:Self-cleaving ribozymes fold into intricate structures, which orient active site groups into catalytically competent conformations. Most ribozyme families have distinct catalytic cores stabilized by tertiary interactions between domains peripheral to those cores. We show that large hepatitis delta virus (HDV)-like rib...

journal_title：Scientific reports

authors： Webb CH,Nguyen D,Myszka M,Lupták A

更新日期：2016-06-15 00:00:00

abstract：:Genetic polymorphisms in drug metabolizing enzymes and drug transporters may affect irinotecan toxicity. Although genetic polymorphisms have been shown to influence the irinotecan toxicity, data are limited in Thai population. Thus, the aim of this study was to assess the allele and genotype frequencies and the relati...

journal_title：Scientific reports

authors： Atasilp C,Chansriwong P,Sirachainan E,Reungwetwattana T,Sirilerttrakul S,Chamnanphon M,Puangpetch A,Sukasem C

更新日期：2020-08-10 00:00:00

abstract：:We have developed an optimized protocol for plasma targeted mRNA sequencing in our previous study. Here, we performed plasma targeted mRNA sequencing for 40 colorectal adenoma patients and 39 colonoscopy-proven normal controls in order to find potential circulating mRNA markers for colorectal adenoma. Results showed t...

journal_title：Scientific reports

authors： Xue VW,Cheung MT,Chan PT,Luk LLY,Lee VH,Au TC,Yu AC,Cho WCS,Tsang HFA,Chan AK,Wong SCC

更新日期：2019-09-10 00:00:00

abstract：:Tissue damage induces rapid recruitment of leukocytes and changes in the transcriptional landscape that influence wound healing. However, the cell-type specific transcriptional changes that influence leukocyte function and tissue repair have not been well characterized. Here, we employed translating ribosome affinity ...

journal_title：Scientific reports

authors： Houseright RA,Rosowski EE,Lam PY,Tauzin SJM,Mulvaney O,Dewey CN,Huttenlocher A

更新日期：2020-09-24 00:00:00

abstract：:Hard carbon attracts wide attentions as the anode for high-energy rechargeable batteries due to its low cost and high theoretical capacities. However, the intrinsically disordered microstructure gives it poor electrical conductivity and unsatisfactory rate performance. Here we report a facile synthesis of N-doped grap...

journal_title：Scientific reports

authors： Wang N,Liu Q,Sun B,Gu J,Yu B,Zhang W,Zhang D

更新日期：2018-07-02 00:00:00

abstract：:A 63-day feeding trial was conducted in northern snakehead to observe the effects of a dietary soybean meal substitution on the microbiota community, morphology and inflammatory cytokine gene expression in the intestine. Four isonitrogenous and isoenergetic diets containing increasing levels of soybean meal were used ...

journal_title：Scientific reports

authors： Miao S,Zhao C,Zhu J,Hu J,Dong X,Sun L

更新日期：2018-01-08 00:00:00

abstract：:Most studies on ungulate reproduction have focused on the covariates of male reproductive success, while there is much less information on female tactics of mate choice. The aim of this work is to fill this gap and to assess condition-dependent variations in female tactics in a lekking fallow deer (Dama dama) populati...

journal_title：Scientific reports

authors： Imperio S,Lombardi S,De Marinis A,Ronchi F,Santini G,Focardi S

更新日期：2020-02-27 00:00:00

abstract：:Tumor necrosis factor is a major pro-inflammatory cytokine which triggers various physiological consequences by binding to and trimerizing its receptors, and has been the single most sought-after drug target for intervening autoimmune diseases such as rheumatoid arthritis and psoriasis. However, current TNF-α blockers...

journal_title：Scientific reports

authors： Cui X,Chang L,Li Y,Lv Q,Wang F,Lin Y,Li W,Meade JD,Walden JC,Liang P

更新日期：2018-05-09 00:00:00

abstract：:Human papillomavirus (HPV) is the most common sexually transmitted infection in the world and the main cause of cervical cancer. Nowadays, the virus-like particles (VLPs) based on L1 proteins have been considered as the best candidate for vaccine development against HPV infections. Two commercial HPV (Gardasil and Cer...

journal_title：Scientific reports

authors： Namvar A,Bolhassani A,Javadi G,Noormohammadi Z

更新日期：2019-10-23 00:00:00

abstract：:Based on the electrical characteristic detection technology, the quantitative prediction models of sensory score and physical and chemical quality Index (theaflavins, thearubigins, and theabrownins) were established by using the fermented products of Congou black tea as the research object. The variation law of electr...

journal_title：Scientific reports

authors： Dong C,An T,Zhu H,Wang J,Hu B,Jiang Y,Yang Y,Li J

更新日期：2020-01-31 00:00:00

abstract：:Magnetic-charge ordering and corresponding magnetic/monopole phase transitions in spin ices are the emergent topics of condensed matter physics. In this work, we investigate a series of magnetic-charge (monopole) phase transitions in artificial square spin ice model using the conserved monopole density algorithm. It i...

journal_title：Scientific reports

authors： Xie YL,Du ZZ,Yan ZB,Liu JM

更新日期：2015-10-29 00:00:00

abstract：:Silk suture material is primarily composed of silk fibroin and regarded as a non-resorbable material. It is slowly degraded by proteolysis when it is implanted into the body. 4-Hexylresorcinol (4HR) is a well-known antiseptic. In this study, the biodegradability of 4HR-incorporated silk sutures were compared to that o...

journal_title：Scientific reports

authors： Jo YY,Kweon H,Kim DW,Kim MK,Kim SG,Kim JY,Chae WS,Hong SP,Park YH,Lee SY,Choi JY

更新日期：2017-02-13 00:00:00

abstract：:It has been postulated that there is a link between age related degenerative diseases and cancer. The TNF-related apoptosis-inducing ligand (TRAIL) has been shown to selectively kill tumor cells by binding to pro-apoptotic and anti-apoptotic receptors. Our aim was to study the levels of anti-apoptotic receptor (DcR1) ...

journal_title：Scientific reports

authors： Anand A,Sharma NK,Singh R,Gupta A,Prabhakar S,Jindal N,Bhatt AK,Sharma SK,Gupta PK

更新日期：2014-02-18 00:00:00

abstract：:We demonstrate a simple and effective strategy for implementing a polarizing beamsplitter for the terahertz spectral region, based on an artificial dielectric medium that is scalable to a range of desired frequencies. The artificial dielectric medium consists of a uniformly spaced stack of metal plates, which is elect...

journal_title：Scientific reports

authors： Mendis R,Nagai M,Zhang W,Mittleman DM

更新日期：2017-07-19 00:00:00