Abstract:
:Background: The COVID-19 pandemic represents an unprecedented global challenge and implicates a wide range of burden on medical professionals. Here, we evaluated the perception of the COVID-19 pandemic among medical professionals in Germany. Methods: A total of n = 2827 medical professionals participated in an online survey between 27 March and 11 April. Results: While most participants stated that Germany was well prepared and rated the measures taken by their employer as positive, subgroup analyses revealed decisive differences. The preventive measures were rated significantly worse by nurses compared to doctors (p < 0.001) and by participants from ambulatory healthcare centres compared to participants from maximum-care hospitals (p < 0.001). Importantly, shortage of protective medical equipment was reported more commonly in the ambulatory sector (p < 0.001) and in East German federal states (p = 0.004). Moreover, the majority of health care professionals (72.4%) reported significant restrictions of daily work routine. Finally, over 60% of medical professionals had concerns regarding their own health, which were more pronounced among female participants (p = 0.024). Conclusion: This survey may indicate starting points on how medical professionals could be supported in carrying out their important activities during the ongoing and future healthcare challenges.
journal_name
Emerg Microbes Infectjournal_title
Emerging microbes & infectionsauthors
Paffenholz P,Peine A,Hellmich M,Paffenholz SV,Martin L,Luedde M,Haverkamp M,Roderburg C,Marx G,Heidenreich A,Trautwein C,Luedde T,Loosen SHdoi
10.1080/22221751.2020.1785951subject
Has Abstractpub_date
2020-12-01 00:00:00pages
1590-1599issue
1issn
2222-1751journal_volume
9pub_type
杂志文章abstract::Little is known about the processes that enable influenza A viruses to jump into new host species. Here we show that the non-structural protein1 nucleotide substitution, A374G, encoding the D125G(GAT→GGT) mutation, which evolved during the adaptation of a human virus within a mouse host, activates a novel donor splice...
journal_title:Emerging microbes & infections
pub_type: 杂志文章
doi:10.1038/emi.2012.38
更新日期:2012-11-01 00:00:00
abstract::We report the first case of severe pneumonia due to co-infection with the emerging avian influenza A (H5N1) virus subclade 2.3.2.1 and Mycoplasma pneumoniae. The patient was a returning traveller who had visited a poultry market in South China. We then review the epidemiology, virology, interspecies barrier limiting p...
journal_title:Emerging microbes & infections
pub_type: 杂志文章,评审
doi:10.1038/emi.2012.24
更新日期:2012-09-01 00:00:00
abstract::Zika virus (ZIKV) has become a threat to global health since the outbreak in Brazil in 2015. Although ZIKV is generally considered an Aedes-transmitted pathogen, new evidence has shown that parts of the virus closely resemble Culex-transmitted viruses. Therefore, it is important to evaluate the competence of Culex spe...
journal_title:Emerging microbes & infections
pub_type: 杂志文章
doi:10.1038/emi.2016.102
更新日期:2016-09-07 00:00:00
abstract::Severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) has resulted in a pandemic and is continuing to spread rapidly around the globe. No effective vaccine is currently available to prevent COVID-19, and intense efforts are being invested worldwide into vaccine development. In this context, all technolo...
journal_title:Emerging microbes & infections
pub_type: 杂志文章
doi:10.1080/22221751.2020.1791737
更新日期:2020-12-01 00:00:00
abstract::Clostridium difficile is the major causative agent of nosocomial antibiotic-associated diarrhea. In a 2009 outbreak of C. difficile-associated diarrhea that was recorded in a major Costa Rican hospital, the hypervirulent NAP1 strain (45%) predominated together with a local genotype variant (NAPCR1, 31%). Both strains ...
journal_title:Emerging microbes & infections
pub_type: 杂志文章
doi:10.1038/emi.2016.38
更新日期:2016-05-11 00:00:00
abstract::Infection with a novel H10N8 influenza virus in humans was first described in China in December 2013, which raised concerns related to public health. This novel virus was subsequently confirmed to have originated from a live poultry market. However, whether this virus can infect other mammals remains unclear. In the p...
journal_title:Emerging microbes & infections
pub_type: 杂志文章
doi:10.1080/22221751.2019.1708811
更新日期:2020-01-03 00:00:00
abstract::Acinetobacter baumannii is a notorious pathogen that has emerged as a healthcare nightmare in recent years because it causes serious infections that are associated with high morbidity and mortality rates. Due to its exceptional ability to acquire resistance to almost all available antibiotics, A. baumannii is currentl...
journal_title:Emerging microbes & infections
pub_type: 杂志文章,评审
doi:10.1038/s41426-018-0030-4
更新日期:2018-03-21 00:00:00
abstract::COVID-19, the worst pandemic in 100 years, has rapidly spread to the entire world in 2 months since its early report in January 2020. Based on the publicly available data sources, we developed a simple mathematic modeling approach to track the outbreaks of COVID-19 in the US and three selected states: New York, Michig...
journal_title:Emerging microbes & infections
pub_type: 信件
doi:10.1080/22221751.2020.1760146
更新日期:2020-12-01 00:00:00
abstract::After three decades of intensive research efforts, an effective vaccine against HIV-1 remains to be developed. Several broadly neutralizing antibodies to HIV-1, such as 10E8, recognize the membrane proximal external region (MPER) of the HIV-1 gp41 protein. Thus, the MPER is considered to be a very important target for...
journal_title:Emerging microbes & infections
pub_type: 杂志文章
doi:10.1038/emi.2016.86
更新日期:2016-06-22 00:00:00
abstract::Dengue virus (DENV) is a mosquito-borne Flavivirus that is endemic in many tropical and sub-tropical countries where the transmission vectors Aedes spp. mosquitoes resides. There are four serotypes of the virus. Each serotype is antigenically different, meaning they elicit heterologous antibodies. Infection with one s...
journal_title:Emerging microbes & infections
pub_type: 杂志文章,评审
doi:10.1038/s41426-018-0168-0
更新日期:2018-10-10 00:00:00
abstract::Worldwide emergence of Salmonella enterica serovar Newport (S. Newport) infection in humans, in parallel with a significant increasing prevalence of antimicrobial resistance (AR), is a serious public health concern. However, the prevalence of S. Newport resistance in China remains largely unknown. A retrospective stud...
journal_title:Emerging microbes & infections
pub_type: 信件
doi:10.1080/22221751.2020.1733439
更新日期:2020-03-03 00:00:00
abstract::Toxoplasmosis is one of the most common zoonotic diseases in the world. Felines excrete environmentally resistant Toxoplasma gondii oocysts. However, there is no direct evidence to prove tigers are the intermediate host of T. gondii. Here, we show that, IgG antibodies to T. gondii in 80% (8/10) of captive tigers. Two ...
journal_title:Emerging microbes & infections
pub_type: 信件
doi:10.1080/22221751.2019.1682471
更新日期:2019-01-01 00:00:00
abstract::Hepatitis C virus (HCV) infection is a major cause of chronic hepatitis and liver cancer worldwide. Adaptive mutations play important roles in the development of the HCV replicon and its infectious clones. We and others have previously identified the p7 mutation F772S and the co-presence of NS4A mutations in infectiou...
journal_title:Emerging microbes & infections
pub_type: 杂志文章
doi:10.1038/s41426-018-0140-z
更新日期:2018-08-08 00:00:00
abstract::Serology detection is recognized for its sensitivity in convalescent patients with COVID-19, in comparison with nucleic acid amplification tests (NAATs). This article aimed to evaluate the diagnostic accuracy of serologic methods for COVID-19 based on assay design and post-symptom-onset intervals. Two authors independ...
journal_title:Emerging microbes & infections
pub_type: 杂志文章,meta分析
doi:10.1080/22221751.2020.1826362
更新日期:2020-12-01 00:00:00
abstract::Pigs play an important role in interspecies transmission of the influenza virus, particularly as "mixing vessels" for reassortment. Two influenza A/H1N1 virus strains, A/swine/Siberia/1sw/2016 and A/swine/Siberia/4sw/2017, were isolated during a surveillance of pigs from private farms in Russia from 2016 to 2017. Ther...
journal_title:Emerging microbes & infections
pub_type: 杂志文章
doi:10.1080/22221751.2019.1673136
更新日期:2019-01-01 00:00:00
abstract::Saffold virus (SAFV), a newly discovered human cardiovirus of the Picornaviridae family, causes widespread infection among children, as shown by previous seroprevalence studies. To determine the host cell range of SAFV and its cytopathogenicity, eight mammalian cell lines that were available in the laboratory were scr...
journal_title:Emerging microbes & infections
pub_type: 杂志文章
doi:10.1038/emi.2014.15
更新日期:2014-02-01 00:00:00
abstract::Influenza has been a long-running health problem and novel antiviral drugs are urgently needed. In pre-clinical studies, we demonstrated broad antiviral activity of D, L-lysine-acetylsalicylate glycine (LASAG) against influenza virus (IV) in cell culture and protection against lethal challenge in mice. LASAG is a comp...
journal_title:Emerging microbes & infections
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1038/s41426-018-0023-3
更新日期:2018-03-07 00:00:00
abstract::Outbreaks of avian influenza virus continue to pose threats to human health. Animal models such as the mouse, ferret, and macaque are used to understand the pathogenesis of avian influenza virus infection in humans. We previously reported that the tree shrew (Tupaia belangeri, family Tupaiidae), which is regarded as a...
journal_title:Emerging microbes & infections
pub_type: 杂志文章
doi:10.1038/s41426-018-0167-1
更新日期:2018-10-10 00:00:00
abstract::Molecular epidemiology of Clostridium difficile infection (CDI) has been extensively studied in North America and Europe; however, limited data on CDI are available in the Asia-Pacific region. A multicentre retrospective study was conducted in this region. C. difficile isolates were subjected to multilocus sequence ty...
journal_title:Emerging microbes & infections
pub_type: 杂志文章
doi:10.1080/22221751.2019.1682472
更新日期:2019-01-01 00:00:00
abstract::Macrolides such as erythromycin are the empirical treatment of Bordetella pertussis infections. China has experienced an increase in erythromycin-resistant B. pertussis isolates since they were first reported in 2013. Here, we undertook a genomic study on Chinese B. pertussis isolates from 2012 to 2015 to elucidate th...
journal_title:Emerging microbes & infections
pub_type: 杂志文章
doi:10.1080/22221751.2019.1587315
更新日期:2019-01-01 00:00:00
abstract::Previous studies have shown that livestock (LA)-MRSA ST398 evolved from a human-adapted methicillin-susceptible S. aureus (MSSA) clone. However, detailed information regarding ST9 is still unclear. Here, we characterized a community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) ST9-SCCmec XII isolat...
journal_title:Emerging microbes & infections
pub_type: 杂志文章
doi:10.1080/22221751.2020.1848354
更新日期:2020-12-01 00:00:00
abstract::Lentiviruses harbour high genetic variability for efficient evasion from host immunity. An attenuated equine infectious anaemia (EIA) vaccine was developed decades ago in China and presented remarkably robust protection against EIA. The vaccine was recently proven to have high genomic diversity, particular in env. How...
journal_title:Emerging microbes & infections
pub_type: 杂志文章
doi:10.1080/22221751.2020.1773323
更新日期:2020-12-01 00:00:00
abstract::Norovirus (NoV) is now recognized as a leading cause of nonbacterial acute gastroenteritis; however, the NoV GII.17 genotype has rarely been reported as the predominant genotype in clinical diarrhea cases. During the winter of 2014–2015, the GII.17 genotype, together with the NoV GII.4 genotype, dominated in sporadic ...
journal_title:Emerging microbes & infections
pub_type: 杂志文章
doi:10.1038/emi.2015.67
更新日期:2015-11-01 00:00:00
abstract::Human coronavirus OC43 (HCoV-OC43) is commonly associated with respiratory tract infections in humans, with five genetically distinct genotypes (A to E) described so far. In this study, we obtained the full-length genomes of HCoV-OC43 strains from two previously unrecognized lineages identified among patients presenti...
journal_title:Emerging microbes & infections
pub_type: 杂志文章
doi:10.1038/emi.2016.132
更新日期:2017-01-04 00:00:00
abstract::Influenza A(H1N1)pdm09 virus has remained in a seasonal circulation since being recognized in 2009. Although it followed a mild course in most patients, in others it caused a series of severe clinical illnesses. Epidemiologic studies have implicated that host factors have a major influence on the disease severity of i...
journal_title:Emerging microbes & infections
pub_type: 杂志文章
doi:10.1080/22221751.2020.1870412
更新日期:2021-12-01 00:00:00
abstract::Interleukin 17 (IL-17) and its closest relative, IL-17F, have recently drawn much attention in the field of immunology. IL-17 and IL-17F are expressed by a distinct type of T cells, T helper 17 cells and certain other lymphocytes. These cytokines play key regulatory roles in host defense and inflammatory diseases. In ...
journal_title:Emerging microbes & infections
pub_type: 杂志文章,评审
doi:10.1038/emi.2013.58
更新日期:2013-09-01 00:00:00
abstract::The progressive anthropization of caves for food resources or economic purposes increases human exposure to pathogens that naturally infect cave-dwelling animals. The presence of wild or domestic animals in the immediate surroundings of caves also may contribute to increasing the risk of emergence of such pathogens. S...
journal_title:Emerging microbes & infections
pub_type: 杂志文章,评审
doi:10.1038/emi.2017.6
更新日期:2017-04-12 00:00:00
abstract::Host switch events of influenza A viruses (IAVs) continuously pose a zoonotic threat to humans. In 2013, swine-origin H1N1 IAVs emerged in dogs soon after they were detected in swine in the Guangxi province of China. This host switch was followed by multiple reassortment events between these H1N1 and previously circul...
journal_title:Emerging microbes & infections
pub_type: 杂志文章
doi:10.1080/22221751.2019.1637284
更新日期:2019-01-01 00:00:00
abstract::Babesiosis is a tick-borne, zoonotic disease caused by Babesia spp. Two cases of babesiosis were detected by nested polymerase chain reaction (PCR) in Yunnan province, China, and further confirmed by molecular assay. The blood smears showed intraerythrocytic ring form and tetrads typical of small B. microti. In both c...
journal_title:Emerging microbes & infections
pub_type: 杂志文章
doi:10.1038/emi.2014.55
更新日期:2014-08-01 00:00:00
abstract::Whooping cough, caused by Bordetella pertussis, has resurged and presents a global health burden worldwide. B. pertussis strains unable to produce the acellular pertussis vaccine component pertactin (Prn), have been emerging and in some countries represent up to 95% of recent clinical isolates. Knowledge on the effect...
journal_title:Emerging microbes & infections
pub_type: 杂志文章
doi:10.1038/s41426-018-0039-8
更新日期:2018-03-21 00:00:00