Tree shrew as a new animal model to study the pathogenesis of avian influenza (H9N2) virus infection.

abstract：:Emerging studies have indicated that some penaeidins restrict virus infection; however, the mechanism(s) involved are poorly understood. In the present study, we uncovered that penaeidins are a novel family of antiviral effectors against white spot syndrome virus (WSSV), which antagonize the envelope proteins to block...

journal_title：Emerging microbes & infections

authors： Xiao B,Fu Q,Niu S,Zhu P,He J,Li C

更新日期：2020-12-01 00:00:00

abstract：:We report the first case of severe pneumonia due to co-infection with the emerging avian influenza A (H5N1) virus subclade 2.3.2.1 and Mycoplasma pneumoniae. The patient was a returning traveller who had visited a poultry market in South China. We then review the epidemiology, virology, interspecies barrier limiting p...

journal_title：Emerging microbes & infections

authors： To KK,Ng KH,Que TL,Chan JM,Tsang KY,Tsang AK,Chen H,Yuen KY

更新日期：2012-09-01 00:00:00

abstract：:Human papillomaviruses (HPV) contribute to most cervical cancers and are considered to be sexually transmitted. However, papillomaviruses are often found in cancers of internal organs, including the stomach, raising the question as to how the viruses gain access to these sites. A possible connection between blood tran...

journal_title：Emerging microbes & infections

authors： Cladel NM,Jiang P,Li JJ,Peng X,Cooper TK,Majerciak V,Balogh KK,Meyer TJ,Brendle SA,Budgeon LR,Shearer DA,Munden R,Cam M,Vallur R,Christensen ND,Zheng ZM,Hu J

更新日期：2019-01-01 00:00:00

abstract：:Influenza has been a long-running health problem and novel antiviral drugs are urgently needed. In pre-clinical studies, we demonstrated broad antiviral activity of D, L-lysine-acetylsalicylate glycine (LASAG) against influenza virus (IV) in cell culture and protection against lethal challenge in mice. LASAG is a comp...

journal_title：Emerging microbes & infections

authors： Scheuch G,Canisius S,Nocker K,Hofmann T,Naumann R,Pleschka S,Ludwig S,Welte T,Planz O

更新日期：2018-03-07 00:00:00

abstract：:Candida albicans is a major human fungal pathogen, capable of switching among a range of morphological types, such as the yeast form, including white and opaque cell types and the GUT (gastrointestinally induced transition) cell type, the filamentous form, including hyphal and pseudohyphal cell types, and chlamydospor...

journal_title：Emerging microbes & infections

authors： Liang W,Guan G,Li C,Nobile CJ,Tao L,Huang G

更新日期：2020-02-21 00:00:00

abstract：:The highly pathogenic avian influenza A (H5N6) virus has caused sporadic human infections with a high case fatality rate. Due to the continuous evolution of this virus subtype and its ability to transmit to humans, there is an urgent need to develop effective antiviral therapeutics. In this study, a murine monoclonal ...

journal_title：Emerging microbes & infections

authors： Zheng Z,Teo SHC,Arularasu SC,Liu Z,Mohd-Ismail NK,Mok CK,Ong CB,Chu JJ,Tan YJ

更新日期：2020-01-06 00:00:00

abstract：:Dengue virus (DENV) is a mosquito-borne Flavivirus that is endemic in many tropical and sub-tropical countries where the transmission vectors Aedes spp. mosquitoes resides. There are four serotypes of the virus. Each serotype is antigenically different, meaning they elicit heterologous antibodies. Infection with one s...

journal_title：Emerging microbes & infections

authors： Uno N,Ross TM

更新日期：2018-10-10 00:00:00

abstract：:From September 2015 to March 2016, hepatitis A notifications in Germany increased by 45% to 699 cases compared to 482 cases in the same period of the previous year. Children aged five to nine years were predominantly affected (22% of all cases in this period). We hypothesized that this increase could be explained by t...

journal_title：Emerging microbes & infections

authors： Michaelis K,Wenzel JJ,Stark K,Faber M

更新日期：2017-04-26 00:00:00

abstract：:The recently emerged novel coronavirus, "severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)", caused a highly contagious disease called coronavirus disease 2019 (COVID-19). The virus was first reported from Wuhan city in China in December, 2019, which in less than three months spread throughout the globe and...

journal_title：Emerging microbes & infections

authors： Lone SA,Ahmad A

更新日期：2020-12-01 00:00:00

abstract：:Worldwide emergence of Salmonella enterica serovar Newport (S. Newport) infection in humans, in parallel with a significant increasing prevalence of antimicrobial resistance (AR), is a serious public health concern. However, the prevalence of S. Newport resistance in China remains largely unknown. A retrospective stud...

journal_title：Emerging microbes & infections

authors： Elbediwi M,Pan H,Biswas S,Li Y,Yue M

更新日期：2020-03-03 00:00:00

abstract：:Norovirus (NoV) is now recognized as a leading cause of nonbacterial acute gastroenteritis; however, the NoV GII.17 genotype has rarely been reported as the predominant genotype in clinical diarrhea cases. During the winter of 2014–2015, the GII.17 genotype, together with the NoV GII.4 genotype, dominated in sporadic ...

journal_title：Emerging microbes & infections

authors： Chen H,Qian F,Xu J,Chan M,Shen Z,Zai S,Shan M,Cai J,Zhang W,He J,Liu Y,Zhang J,Yuan Z,Zhu Z,Hu Y

更新日期：2015-11-01 00:00:00

abstract：:Echinocandin resistance in Candida glabrata poses a serious clinical challenge. The underlying resistance mechanism of a pan-echinocandin-resistant C. glabrata isolate (strain L74) was investigated in this study. FKS mutants carrying specific mutations found in L74 were reconstructed by the Alt-R CRISPR-Cas9 system (F...

journal_title：Emerging microbes & infections

authors： Hou X,Healey KR,Shor E,Kordalewska M,Ortigosa CJ,Paderu P,Xiao M,Wang H,Zhao Y,Lin LY,Zhang YH,Li YZ,Xu YC,Perlin DS,Zhao Y

更新日期：2019-01-01 00:00:00

abstract：:Macrolides such as erythromycin are the empirical treatment of Bordetella pertussis infections. China has experienced an increase in erythromycin-resistant B. pertussis isolates since they were first reported in 2013. Here, we undertook a genomic study on Chinese B. pertussis isolates from 2012 to 2015 to elucidate th...

journal_title：Emerging microbes & infections

authors： Xu Z,Wang Z,Luan Y,Li Y,Liu X,Peng X,Octavia S,Payne M,Lan R

更新日期：2019-01-01 00:00:00

abstract：:Although not previously known to cause human infections, Kocuria species have now emerged as human pathogens, mostly in compromised hosts with severe underlying disease. Recently, there has been an increasing incidence of different types of Kocuria infections reported, most likely due to the adoption of better identif...

journal_title：Emerging microbes & infections

authors： Purty S,Saranathan R,Prashanth K,Narayanan K,Asir J,Sheela Devi C,Kumar Amarnath S

更新日期：2013-10-01 00:00:00

abstract：:Background: The COVID-19 pandemic represents an unprecedented global challenge and implicates a wide range of burden on medical professionals. Here, we evaluated the perception of the COVID-19 pandemic among medical professionals in Germany. Methods: A total of n = 2827 medical professionals participated in an online ...

journal_title：Emerging microbes & infections

authors： Paffenholz P,Peine A,Hellmich M,Paffenholz SV,Martin L,Luedde M,Haverkamp M,Roderburg C,Marx G,Heidenreich A,Trautwein C,Luedde T,Loosen SH

更新日期：2020-12-01 00:00:00

abstract：:Interleukin 17 (IL-17) and its closest relative, IL-17F, have recently drawn much attention in the field of immunology. IL-17 and IL-17F are expressed by a distinct type of T cells, T helper 17 cells and certain other lymphocytes. These cytokines play key regulatory roles in host defense and inflammatory diseases. In ...

journal_title：Emerging microbes & infections

authors： Jin W,Dong C

更新日期：2013-09-01 00:00:00

abstract：:Serology detection is recognized for its sensitivity in convalescent patients with COVID-19, in comparison with nucleic acid amplification tests (NAATs). This article aimed to evaluate the diagnostic accuracy of serologic methods for COVID-19 based on assay design and post-symptom-onset intervals. Two authors independ...

journal_title：Emerging microbes & infections

authors： Wang H,Ai J,Loeffelholz MJ,Tang YW,Zhang W

更新日期：2020-12-01 00:00:00

abstract：:Tigecycline is regarded as a last-resort treatment for carbapenem-resistant Enterobacteriaceae (CRE), however, the emergence of tigecycline heteroresistance has posted the therapeutic challenge to combat this "nightmare bacteria". The primary purpose of this study was to demonstrate the existence of tigecycline hetero...

journal_title：Emerging microbes & infections

authors： Liu H,Jia X,Zou H,Sun S,Li S,Wang Y,Xia Y

更新日期：2019-01-01 00:00:00

abstract：:We conducted this study to describe the dynamics of the acquisition of respiratory pathogens, their potential interactions and risk factors for possible lower respiratory tract infection symptoms (LRTI) among French pilgrims during the 2018 Hajj. Each participant underwent four successive systematic nasopharyngeal swa...

journal_title：Emerging microbes & infections

authors： Hoang VT,Dao TL,Ly TDA,Belhouchat K,Chaht KL,Gaudart J,Mrenda BM,Drali T,Yezli S,Alotaibi B,Fournier PE,Raoult D,Parola P,de Santi VP,Gautret P

更新日期：2019-01-01 00:00:00

abstract：:Human enterovirus 68 (EV-D68) is a rarely reported virus that has been linked to respiratory disease. In recent years, reports about EV-D68 infection have markedly increased worldwide. However, the epidemiological features of this emerging infection are not well understood. To evaluate the emerging EV-D68 epidemic, we...

journal_title：Emerging microbes & infections

authors： Xiang Z,Li L,Ren L,Guo L,Xie Z,Liu C,Li T,Luo M,Paranhos-Baccalà G,Xu W,Wang J

更新日期：2017-05-10 00:00:00

abstract：:Influenza A(H1N1)pdm09 virus has remained in a seasonal circulation since being recognized in 2009. Although it followed a mild course in most patients, in others it caused a series of severe clinical illnesses. Epidemiologic studies have implicated that host factors have a major influence on the disease severity of i...

journal_title：Emerging microbes & infections

authors： Li M,Chen Y,Chen T,Hu S,Chen L,Shen L,Li F,Yang J,Sun Y,Wang D,He L,Qin S,Shu Y

更新日期：2021-12-01 00:00:00

abstract：:A 78-year-old woman with a long-term ankle spacer with antibacterials developed an intra-articular Candida auris infection. Treatment with systemic antifungal therapy plus an amphotericin B moulded cement spacer was successful. ...

journal_title：Emerging microbes & infections

authors： Roberts SC,Zembower TR,Bolon MK,Kadakia AR,Gilley JH,Ko JH,Clark J,Ward-Fore S,Taiwo BO

更新日期：2019-01-01 00:00:00

abstract：:Coxsackievirus A16 (CA16) is a member of the Picornaviridae family and causes mild and self-limiting hand, foot, and mouth disease (HFMD) in infants and young children. CA16 infection can also progress to central nervous system (CNS) complications; however, the underlying mechanism by which CA16 penetrates the blood-b...

journal_title：Emerging microbes & infections

authors： Song J,Hu Y,Li H,Huang X,Zheng H,Hu Y,Wang J,Jiang X,Li J,Yang Z,Fan H,Guo L,Shi H,He Z,Yang F,Wang X,Dong S,Li Q,Liu L

更新日期：2018-09-19 00:00:00

abstract：:The three unprecedented outbreaks of emerging human coronavirus (HCoV) infections at the beginning of the twenty-first century have highlighted the necessity for readily available, accurate and fast diagnostic testing methods. The laboratory diagnostic methods for human coronavirus infections have evolved substantiall...

journal_title：Emerging microbes & infections

authors： Loeffelholz MJ,Tang YW

更新日期：2020-12-01 00:00:00

abstract：:Coronavirus disease 2019 (COVID-19) is an infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with droplets and contact as the main means of transmission. Since the first case appeared in Wuhan, China, in December 2019, the outbreak has gradually spread nationwide. Up to now, acco...

journal_title：Emerging microbes & infections

authors： Lin L,Lu L,Cao W,Li T

更新日期：2020-12-01 00:00:00

abstract：:Tick-borne encephalitis virus (TBEV) has been classified into three subtypes, namely the European (Eu-TBEV), Far Eastern (FE-TBEV), and Siberian (Sib-TBEV). In this study, we discovered a new subtype of TBEV in wild rodent Marmota himalayana in Qinghai-Tibet Plateau in China, proposed as subtype Himalayan (Him-TBEV). ...

journal_title：Emerging microbes & infections

authors： Dai X,Shang G,Lu S,Yang J,Xu J

更新日期：2018-04-25 00:00:00

abstract：:Histoplasmosis caused by the fungus Histoplasma capsulatum is often lethal in patients with AIDS. Urine antigen testing is highly sensitive and much quicker for diagnosis than culture. Histoplasmosis has a patchy and incompletely appreciated distribution around the world especially in South East Asia. We conducted a s...

journal_title：Emerging microbes & infections

authors： Baker J,Setianingrum F,Wahyuningsih R,Denning DW

更新日期：2019-01-01 00:00:00

abstract：:Babesiosis is a tick-borne, zoonotic disease caused by Babesia spp. Two cases of babesiosis were detected by nested polymerase chain reaction (PCR) in Yunnan province, China, and further confirmed by molecular assay. The blood smears showed intraerythrocytic ring form and tetrads typical of small B. microti. In both c...

journal_title：Emerging microbes & infections

authors： Zhou X,Li SG,Wang JZ,Huang JL,Zhou HJ,Chen JH,Zhou XN

更新日期：2014-08-01 00:00:00

abstract：:In March 2013, a patient infected with a novel avian influenza A H7N9 virus was reported in China. Since then, there have been 458 confirmed infection cases and 177 deaths. The virus contains several human-adapted markers, indicating that H7N9 has pandemic potential. The outbreak of this new influenza virus highlighte...

journal_title：Emerging microbes & infections

authors： Leung HC,Chan CC,Poon VK,Zhao HJ,Cheung CY,Ng F,Huang JD,Zheng BJ

更新日期：2015-04-01 00:00:00

abstract：:Toxoplasmosis is one of the most common zoonotic diseases in the world. Felines excrete environmentally resistant Toxoplasma gondii oocysts. However, there is no direct evidence to prove tigers are the intermediate host of T. gondii. Here, we show that, IgG antibodies to T. gondii in 80% (8/10) of captive tigers. Two ...

journal_title：Emerging microbes & infections

authors： Yang Y,Dong H,Su R,Jiang N,Li T,Su C,Yuan Z,Zhang L

更新日期：2019-01-01 00:00:00