Culex pipiens quinquefasciatus: a potential vector to transmit Zika virus.

abstract：:Although a number of standardized human immunodeficiency virus 1 (HIV-1) pseudoviruses have been generated to assess neutralizing antibodies, subtype B/B' has not been comprehensively characterized either genotypically or phenotypically. Full-length env genes were isolated from plasma samples derived from B/B'-infecte...

journal_title：Emerging microbes & infections

authors： Xie H,Nie J,Chen Q,Huang W,Wang Y

更新日期：2018-05-16 00:00:00

abstract：:Accumulating evidence indicates that bacterial metabolism plays an important role in virulence. Acetyl phosphate (AcP), the high-energy intermediate of the phosphotransacetylase-acetate kinase pathway, is the major acetyl donor in E. coli. PhoP is an essential transcription factor for bacterial virulence. Here, we sho...

journal_title：Emerging microbes & infections

authors： Ren J,Sang Y,Qin R,Su Y,Cui Z,Mang Z,Li H,Lu S,Zhang J,Cheng S,Liu X,Li J,Lu J,Wu W,Zhao GP,Shao F,Yao YF

更新日期：2019-01-01 00:00:00

abstract：:We report the first case of severe pneumonia due to co-infection with the emerging avian influenza A (H5N1) virus subclade 2.3.2.1 and Mycoplasma pneumoniae. The patient was a returning traveller who had visited a poultry market in South China. We then review the epidemiology, virology, interspecies barrier limiting p...

journal_title：Emerging microbes & infections

authors： To KK,Ng KH,Que TL,Chan JM,Tsang KY,Tsang AK,Chen H,Yuen KY

更新日期：2012-09-01 00:00:00

abstract：:GRP78/BiP is an endoplasmic reticulum (ER) chaperone protein with the important function of maintaining ER homeostasis, and the overexpression of GRP78/BiP alleviates ER stress. Our previous studies showed that infection with enterovirus 71 (EV71), a (+)RNA picornavirus, induced GRP78/BiP upregulation; however, ectopi...

journal_title：Emerging microbes & infections

authors： Jheng JR,Wang SC,Jheng CR,Horng JT

更新日期：2016-03-23 00:00:00

abstract：:Norovirus (NoV) is now recognized as a leading cause of nonbacterial acute gastroenteritis; however, the NoV GII.17 genotype has rarely been reported as the predominant genotype in clinical diarrhea cases. During the winter of 2014–2015, the GII.17 genotype, together with the NoV GII.4 genotype, dominated in sporadic ...

journal_title：Emerging microbes & infections

authors： Chen H,Qian F,Xu J,Chan M,Shen Z,Zai S,Shan M,Cai J,Zhang W,He J,Liu Y,Zhang J,Yuan Z,Zhu Z,Hu Y

更新日期：2015-11-01 00:00:00

abstract：:Zika virus (ZIKV) infection during pregnancy is associated with congenital brain abnormalities, a finding that highlights the urgent need to understand mother-to-fetus transmission mechanisms. Human umbilical cord mesenchymal stem cells (hUCMSCs) are susceptible to ZIKV infection but the underlying mechanisms of viral...

journal_title：Emerging microbes & infections

authors： Seong RK,Lee JK,Cho GJ,Kumar M,Shin OS

更新日期：2020-12-01 00:00:00

abstract：:Nontuberculous mycobacterial (NTM) infections in humans have increased in prevalence in recent decades. Mycobacterium kansasii is one of the most prevalent human pathogenic NTM species worldwide. Herein, we report the first isolation of M. kansasii from an indoor domestic cat in Japan. Comparative genome sequence anal...

journal_title：Emerging microbes & infections

authors： Fukano H,Terazono T,Hirabayashi A,Yoshida M,Suzuki M,Wada S,Ishii N,Hoshino Y

更新日期：2021-01-19 00:00:00

abstract：:Clostridium difficile is the major causative agent of nosocomial antibiotic-associated diarrhea. In a 2009 outbreak of C. difficile-associated diarrhea that was recorded in a major Costa Rican hospital, the hypervirulent NAP1 strain (45%) predominated together with a local genotype variant (NAPCR1, 31%). Both strains ...

journal_title：Emerging microbes & infections

authors： López-Ureña D,Quesada-Gómez C,Montoya-Ramírez M,del Mar Gamboa-Coronado M,Somogyi T,Rodríguez C,Rodríguez-Cavallini E

更新日期：2016-05-11 00:00:00

abstract：:Shiga toxin (Stx)-producing Escherichia coli (STEC) can cause a wide range of symptoms from asymptomatic carriage, mild diarrhea to bloody diarrhea (BD) and hemolytic uremic syndrome (HUS). Intimin, encoded by the eae gene, also plays a critical role in STEC pathogenesis. Herein, we investigated the prevalence and gen...

journal_title：Emerging microbes & infections

authors： Hua Y,Bai X,Zhang J,Jernberg C,Chromek M,Hansson S,Frykman A,Yang X,Xiong Y,Wan C,Matussek A

更新日期：2020-12-01 00:00:00

abstract：:Avian influenza A(H7N9) virus (A(H7N9)) emerged in February 2013. Liver impairment of unknown cause is present in 29% of patients with A(H7N9) infection, some of whom experience severe liver injury. Hypoxic hepatitis (HH) is a type of acute severe liver injury characterized by an abrupt, massive increase in serum amin...

journal_title：Emerging microbes & infections

authors： Zhang Y,Liu J,Yu L,Zhou N,Ding W,Zheng S,Shi D,Li L

更新日期：2016-01-06 00:00:00

abstract：:Pigs play an important role in interspecies transmission of the influenza virus, particularly as "mixing vessels" for reassortment. Two influenza A/H1N1 virus strains, A/swine/Siberia/1sw/2016 and A/swine/Siberia/4sw/2017, were isolated during a surveillance of pigs from private farms in Russia from 2016 to 2017. Ther...

journal_title：Emerging microbes & infections

authors： Sobolev I,Kurskaya O,Leonov S,Kabilov M,Alikina T,Alekseev A,Yushkov Y,Saito T,Uchida Y,Mine J,Shestopalov A,Sharshov K

更新日期：2019-01-01 00:00:00

abstract：:Acute meningoencephalitis (AME) is associated with considerable morbidity and mortality in children in developing countries. Clinical specimens were collected from children presenting with AME at two Cambodian paediatric hospitals to determine the major aetiologies associated with AME in the country. Cerebrospinal flu...

journal_title：Emerging microbes & infections

authors： Horwood PF,Duong V,Laurent D,Mey C,Sothy H,Santy K,Richner B,Heng S,Hem S,Cheval J,Gorman C,Dussart P,de Jong MD,Kerleguer A,Guillard B,Murgue B,Lecuit M,de Lamballerie X,Farrar JJ,Tarantola A,Eloit M,Buchy P

更新日期：2017-05-24 00:00:00

abstract：:Pyrazinamide (PZA) is a key antibiotic in current anti-tuberculosis regimens. Although the WHO has stressed the urgent need to obtain data on PZA resistance, in high tuberculosis burden countries, little is known about the level of PZA resistance, the genetic basis of such resistance or its link with Mycobacterium tub...

journal_title：Emerging microbes & infections

authors： Huy NQ,Lucie C,Hoa TTT,Hung NV,Lan NTN,Son NT,Nhung NV,Anh DD,Anne-Laure B,Van Anh NT

更新日期：2017-10-11 00:00:00

abstract：:We report the discovery and confirmation of 23 novel mutations with previously undocumented role in isoniazid (INH) drug resistance, in catalase-peroxidase (katG) gene of Mycobacterium tuberculosis (Mtb) isolates. With these mutations, a synonymous mutation in fabG1 (g609a), and two canonical mutations, we were able t...

journal_title：Emerging microbes & infections

authors： Torres JN,Paul LV,Rodwell TC,Victor TC,Amallraja AM,Elghraoui A,Goodmanson AP,Ramirez-Busby SM,Chawla A,Zadorozhny V,Streicher EM,Sirgel FA,Catanzaro D,Rodrigues C,Gler MT,Crudu V,Catanzaro A,Valafar F

更新日期：2015-07-01 00:00:00

abstract：:West Nile virus (WNV) is an arthropod-borne flavivirus of high medical and veterinary importance. The main vectors for WNV are mosquito species of the Culex genus that transmit WNV among birds, and occasionally to humans and horses, which are 'dead-end' hosts. Recently, several studies have been published that aimed t...

journal_title：Emerging microbes & infections

authors： Vogels CB,Göertz GP,Pijlman GP,Koenraadt CJ

更新日期：2017-11-08 00:00:00

abstract：:Tigecycline is regarded as a last-resort treatment for carbapenem-resistant Enterobacteriaceae (CRE), however, the emergence of tigecycline heteroresistance has posted the therapeutic challenge to combat this "nightmare bacteria". The primary purpose of this study was to demonstrate the existence of tigecycline hetero...

journal_title：Emerging microbes & infections

authors： Liu H,Jia X,Zou H,Sun S,Li S,Wang Y,Xia Y

更新日期：2019-01-01 00:00:00

abstract：:Saffold virus (SAFV), a newly discovered human cardiovirus of the Picornaviridae family, causes widespread infection among children, as shown by previous seroprevalence studies. To determine the host cell range of SAFV and its cytopathogenicity, eight mammalian cell lines that were available in the laboratory were scr...

journal_title：Emerging microbes & infections

authors： Xu Y,Victorio CB,Ng Q,Tan YJ,Chua KB

更新日期：2014-02-01 00:00:00

abstract：:Human enteroviruses frequently cause severe diseases in children. Human enteroviruses are transmitted via the fecal-oral route and respiratory droplets, and primary replication occurs in the gastro-intestinal and respiratory tracts; however, how enteroviruses infect these sites is largely unknown. Human intestinal org...

journal_title：Emerging microbes & infections

authors： van der Sanden SMG,Sachs N,Koekkoek SM,Koen G,Pajkrt D,Clevers H,Wolthers KC

更新日期：2018-05-09 00:00:00

abstract：:Emerging studies have indicated that some penaeidins restrict virus infection; however, the mechanism(s) involved are poorly understood. In the present study, we uncovered that penaeidins are a novel family of antiviral effectors against white spot syndrome virus (WSSV), which antagonize the envelope proteins to block...

journal_title：Emerging microbes & infections

authors： Xiao B,Fu Q,Niu S,Zhu P,He J,Li C

更新日期：2020-12-01 00:00:00

abstract：:In March 2013, a patient infected with a novel avian influenza A H7N9 virus was reported in China. Since then, there have been 458 confirmed infection cases and 177 deaths. The virus contains several human-adapted markers, indicating that H7N9 has pandemic potential. The outbreak of this new influenza virus highlighte...

journal_title：Emerging microbes & infections

authors： Leung HC,Chan CC,Poon VK,Zhao HJ,Cheung CY,Ng F,Huang JD,Zheng BJ

更新日期：2015-04-01 00:00:00

abstract：:Influenza viruses of the H4 subtype are widespread in wild birds, circulate in domestic poultry, readily infect mammals, and tolerate the insertion of a polybasic cleavage site. In addition, serological evidence suggests that humans working with poultry are exposed to these viruses. While H4 viruses are not of immedia...

journal_title：Emerging microbes & infections

authors： Amanat F,Meade P,Strohmeier S,Krammer F

更新日期：2019-01-01 00:00:00

abstract：:Klebsiella pneumoniae carbapenemase (KPC)-producing K. pneumoniae (KPC-KP) have disseminated worldwide and emerged as major threats to public health. Of epidemiological significance, the international pandemic of KPC-KP is primarily associated with CG258 isolates and blaKPC-IncF plasmids. CRISPR-Cas system is an adapt...

journal_title：Emerging microbes & infections

authors： Zhou Y,Tang Y,Fu P,Tian D,Yu L,Huang Y,Li G,Li M,Wang Y,Yang Z,Xu X,Yin Z,Zhou D,Poirel L,Jiang X

更新日期：2020-12-01 00:00:00

abstract：:After three decades of intensive research efforts, an effective vaccine against HIV-1 remains to be developed. Several broadly neutralizing antibodies to HIV-1, such as 10E8, recognize the membrane proximal external region (MPER) of the HIV-1 gp41 protein. Thus, the MPER is considered to be a very important target for...

journal_title：Emerging microbes & infections

authors： Sun Z,Zhu Y,Wang Q,Ye L,Dai Y,Su S,Yu F,Ying T,Yang C,Jiang S,Lu L

更新日期：2016-06-22 00:00:00

abstract：:Severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) has resulted in a pandemic and is continuing to spread rapidly around the globe. No effective vaccine is currently available to prevent COVID-19, and intense efforts are being invested worldwide into vaccine development. In this context, all technolo...

journal_title：Emerging microbes & infections

authors： Grenga L,Gallais F,Pible O,Gaillard JC,Gouveia D,Batina H,Bazaline N,Ruat S,Culotta K,Miotello G,Debroas S,Roncato MA,Steinmetz G,Foissard C,Desplan A,Alpha-Bazin B,Almunia C,Gas F,Bellanger L,Armengaud J

更新日期：2020-12-01 00:00:00

abstract：:Host switch events of influenza A viruses (IAVs) continuously pose a zoonotic threat to humans. In 2013, swine-origin H1N1 IAVs emerged in dogs soon after they were detected in swine in the Guangxi province of China. This host switch was followed by multiple reassortment events between these H1N1 and previously circul...

journal_title：Emerging microbes & infections

authors： Wang G,Dos Anjos Borges LG,Stadlbauer D,Ramos I,Bermúdez González MC,He J,Ding Y,Wei Z,Ouyang K,Huang W,Simon V,Fernandez-Sesma A,Krammer F,Nelson MI,Chen Y,García-Sastre A

更新日期：2019-01-01 00:00:00

abstract：:The Beijing genotype comprises a highly disseminated strain type that is frequently associated with multidrug resistant (MDR) tuberculosis (TB) and increased transmissibility but, countries such as Portugal and Guinea-Bissau fall outside the regions phylogeographically associated with this specific genotype. Neverthel...

journal_title：Emerging microbes & infections

authors： Perdigão J,Silva C,Maltez F,Machado D,Miranda A,Couto I,Rabna P,Florez de Sessions P,Phelan J,Pain A,McNerney R,Hibberd ML,Mokrousov I,Clark TG,Viveiros M,Portugal I

更新日期：2020-12-01 00:00:00

abstract：:Coxsackievirus A16 (CA16) is a member of the Picornaviridae family and causes mild and self-limiting hand, foot, and mouth disease (HFMD) in infants and young children. CA16 infection can also progress to central nervous system (CNS) complications; however, the underlying mechanism by which CA16 penetrates the blood-b...

journal_title：Emerging microbes & infections

authors： Song J,Hu Y,Li H,Huang X,Zheng H,Hu Y,Wang J,Jiang X,Li J,Yang Z,Fan H,Guo L,Shi H,He Z,Yang F,Wang X,Dong S,Li Q,Liu L

更新日期：2018-09-19 00:00:00

abstract：:Tick-borne encephalitis virus (TBEV) has been classified into three subtypes, namely the European (Eu-TBEV), Far Eastern (FE-TBEV), and Siberian (Sib-TBEV). In this study, we discovered a new subtype of TBEV in wild rodent Marmota himalayana in Qinghai-Tibet Plateau in China, proposed as subtype Himalayan (Him-TBEV). ...

journal_title：Emerging microbes & infections

authors： Dai X,Shang G,Lu S,Yang J,Xu J

更新日期：2018-04-25 00:00:00

abstract：:The recently emerged novel coronavirus, "severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)", caused a highly contagious disease called coronavirus disease 2019 (COVID-19). The virus was first reported from Wuhan city in China in December, 2019, which in less than three months spread throughout the globe and...

journal_title：Emerging microbes & infections

authors： Lone SA,Ahmad A

更新日期：2020-12-01 00:00:00

abstract：:Human enterovirus 68 (EV-D68) is a rarely reported virus that has been linked to respiratory disease. In recent years, reports about EV-D68 infection have markedly increased worldwide. However, the epidemiological features of this emerging infection are not well understood. To evaluate the emerging EV-D68 epidemic, we...

journal_title：Emerging microbes & infections

authors： Xiang Z,Li L,Ren L,Guo L,Xie Z,Liu C,Li T,Luo M,Paranhos-Baccalà G,Xu W,Wang J

更新日期：2017-05-10 00:00:00