Dengue virus and the host innate immune response.

abstract：:The continuing pandemic threat posed by avian influenza A/H5N1 viruses calls for improved insights into their evolution during human infection. We performed whole genome deep sequencing of respiratory specimens from 44 H5N1-infected individuals from Indonesia and found substantial within-host viral diversity. At nearl...

journal_title：Emerging microbes & infections

authors： Welkers MRA,Pawestri HA,Fonville JM,Sampurno OD,Pater M,Holwerda M,Han AX,Russell CA,Jeeninga RE,Setiawaty V,de Jong MD,Eggink D

更新日期：2019-01-01 00:00:00

abstract：:Zika virus (ZIKV) infection during pregnancy is associated with congenital brain abnormalities, a finding that highlights the urgent need to understand mother-to-fetus transmission mechanisms. Human umbilical cord mesenchymal stem cells (hUCMSCs) are susceptible to ZIKV infection but the underlying mechanisms of viral...

journal_title：Emerging microbes & infections

authors： Seong RK,Lee JK,Cho GJ,Kumar M,Shin OS

更新日期：2020-12-01 00:00:00

abstract：:Tick-borne encephalitis virus (TBEV) has been classified into three subtypes, namely the European (Eu-TBEV), Far Eastern (FE-TBEV), and Siberian (Sib-TBEV). In this study, we discovered a new subtype of TBEV in wild rodent Marmota himalayana in Qinghai-Tibet Plateau in China, proposed as subtype Himalayan (Him-TBEV). ...

journal_title：Emerging microbes & infections

authors： Dai X,Shang G,Lu S,Yang J,Xu J

更新日期：2018-04-25 00:00:00

abstract：:The progressive anthropization of caves for food resources or economic purposes increases human exposure to pathogens that naturally infect cave-dwelling animals. The presence of wild or domestic animals in the immediate surroundings of caves also may contribute to increasing the risk of emergence of such pathogens. S...

journal_title：Emerging microbes & infections

authors： Obame-Nkoghe J,Leroy EM,Paupy C

更新日期：2017-04-12 00:00:00

abstract：:The Beijing genotype comprises a highly disseminated strain type that is frequently associated with multidrug resistant (MDR) tuberculosis (TB) and increased transmissibility but, countries such as Portugal and Guinea-Bissau fall outside the regions phylogeographically associated with this specific genotype. Neverthel...

journal_title：Emerging microbes & infections

authors： Perdigão J,Silva C,Maltez F,Machado D,Miranda A,Couto I,Rabna P,Florez de Sessions P,Phelan J,Pain A,McNerney R,Hibberd ML,Mokrousov I,Clark TG,Viveiros M,Portugal I

更新日期：2020-12-01 00:00:00

abstract：:Accumulating evidence indicates that bacterial metabolism plays an important role in virulence. Acetyl phosphate (AcP), the high-energy intermediate of the phosphotransacetylase-acetate kinase pathway, is the major acetyl donor in E. coli. PhoP is an essential transcription factor for bacterial virulence. Here, we sho...

journal_title：Emerging microbes & infections

authors： Ren J,Sang Y,Qin R,Su Y,Cui Z,Mang Z,Li H,Lu S,Zhang J,Cheng S,Liu X,Li J,Lu J,Wu W,Zhao GP,Shao F,Yao YF

更新日期：2019-01-01 00:00:00

abstract：:Background: The COVID-19 pandemic represents an unprecedented global challenge and implicates a wide range of burden on medical professionals. Here, we evaluated the perception of the COVID-19 pandemic among medical professionals in Germany. Methods: A total of n = 2827 medical professionals participated in an online ...

journal_title：Emerging microbes & infections

authors： Paffenholz P,Peine A,Hellmich M,Paffenholz SV,Martin L,Luedde M,Haverkamp M,Roderburg C,Marx G,Heidenreich A,Trautwein C,Luedde T,Loosen SH

更新日期：2020-12-01 00:00:00

abstract：:Infection with a novel H10N8 influenza virus in humans was first described in China in December 2013, which raised concerns related to public health. This novel virus was subsequently confirmed to have originated from a live poultry market. However, whether this virus can infect other mammals remains unclear. In the p...

journal_title：Emerging microbes & infections

authors： Fu X,Huang Y,Fang B,Liu Y,Cai M,Zhong R,Huang J,Wenbao Q,Tian Y,Zhang G

更新日期：2020-01-03 00:00:00

abstract：:Zika virus (ZIKV) has become a threat to global health since the outbreak in Brazil in 2015. Although ZIKV is generally considered an Aedes-transmitted pathogen, new evidence has shown that parts of the virus closely resemble Culex-transmitted viruses. Therefore, it is important to evaluate the competence of Culex spe...

journal_title：Emerging microbes & infections

authors： Guo XX,Li CX,Deng YQ,Xing D,Liu QM,Wu Q,Sun AJ,Dong YD,Cao WC,Qin CF,Zhao TY

更新日期：2016-09-07 00:00:00

abstract：:Human coronavirus OC43 (HCoV-OC43) is commonly associated with respiratory tract infections in humans, with five genetically distinct genotypes (A to E) described so far. In this study, we obtained the full-length genomes of HCoV-OC43 strains from two previously unrecognized lineages identified among patients presenti...

journal_title：Emerging microbes & infections

authors： Oong XY,Ng KT,Takebe Y,Ng LJ,Chan KG,Chook JB,Kamarulzaman A,Tee KK

更新日期：2017-01-04 00:00:00

abstract：:Klebsiella pneumoniae carbapenemase (KPC)-producing K. pneumoniae (KPC-KP) have disseminated worldwide and emerged as major threats to public health. Of epidemiological significance, the international pandemic of KPC-KP is primarily associated with CG258 isolates and blaKPC-IncF plasmids. CRISPR-Cas system is an adapt...

journal_title：Emerging microbes & infections

authors： Zhou Y,Tang Y,Fu P,Tian D,Yu L,Huang Y,Li G,Li M,Wang Y,Yang Z,Xu X,Yin Z,Zhou D,Poirel L,Jiang X

更新日期：2020-12-01 00:00:00

abstract：:Previous studies have shown that livestock (LA)-MRSA ST398 evolved from a human-adapted methicillin-susceptible S. aureus (MSSA) clone. However, detailed information regarding ST9 is still unclear. Here, we characterized a community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) ST9-SCCmec XII isolat...

journal_title：Emerging microbes & infections

authors： Jin Y,Yu X,Chen Y,Chen W,Shen P,Luo Q,Zhang S,Kong X,Zheng B,Xiao Y

更新日期：2020-12-01 00:00:00

abstract：:The emergence of SARS-CoV-2 has led to the current global coronavirus pandemic and more than one million infections since December 2019. The exact origin of SARS-CoV-2 remains elusive, but the presence of a distinct motif in the S1/S2 junction region suggests the possible acquisition of cleavage site(s) in the spike p...

journal_title：Emerging microbes & infections

authors： Lau SY,Wang P,Mok BW,Zhang AJ,Chu H,Lee AC,Deng S,Chen P,Chan KH,Song W,Chen Z,To KK,Chan JF,Yuen KY,Chen H

更新日期：2020-12-01 00:00:00

abstract：:Severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) has resulted in a pandemic and is continuing to spread rapidly around the globe. No effective vaccine is currently available to prevent COVID-19, and intense efforts are being invested worldwide into vaccine development. In this context, all technolo...

journal_title：Emerging microbes & infections

authors： Grenga L,Gallais F,Pible O,Gaillard JC,Gouveia D,Batina H,Bazaline N,Ruat S,Culotta K,Miotello G,Debroas S,Roncato MA,Steinmetz G,Foissard C,Desplan A,Alpha-Bazin B,Almunia C,Gas F,Bellanger L,Armengaud J

更新日期：2020-12-01 00:00:00

abstract：:Tigecycline is regarded as a last-resort treatment for carbapenem-resistant Enterobacteriaceae (CRE), however, the emergence of tigecycline heteroresistance has posted the therapeutic challenge to combat this "nightmare bacteria". The primary purpose of this study was to demonstrate the existence of tigecycline hetero...

journal_title：Emerging microbes & infections

authors： Liu H,Jia X,Zou H,Sun S,Li S,Wang Y,Xia Y

更新日期：2019-01-01 00:00:00

abstract：:Norovirus (NoV) is now recognized as a leading cause of nonbacterial acute gastroenteritis; however, the NoV GII.17 genotype has rarely been reported as the predominant genotype in clinical diarrhea cases. During the winter of 2014–2015, the GII.17 genotype, together with the NoV GII.4 genotype, dominated in sporadic ...

journal_title：Emerging microbes & infections

authors： Chen H,Qian F,Xu J,Chan M,Shen Z,Zai S,Shan M,Cai J,Zhang W,He J,Liu Y,Zhang J,Yuan Z,Zhu Z,Hu Y

更新日期：2015-11-01 00:00:00

abstract：:Molecular epidemiology of Clostridium difficile infection (CDI) has been extensively studied in North America and Europe; however, limited data on CDI are available in the Asia-Pacific region. A multicentre retrospective study was conducted in this region. C. difficile isolates were subjected to multilocus sequence ty...

journal_title：Emerging microbes & infections

authors： Luo Y,Cheong E,Bian Q,Collins DA,Ye J,Shin JH,Yam WC,Takata T,Song X,Wang X,Kamboj M,Gottlieb T,Jiang J,Riley TV,Tang YW,Jin D

更新日期：2019-01-01 00:00:00

abstract：:Human papillomaviruses (HPV) contribute to most cervical cancers and are considered to be sexually transmitted. However, papillomaviruses are often found in cancers of internal organs, including the stomach, raising the question as to how the viruses gain access to these sites. A possible connection between blood tran...

journal_title：Emerging microbes & infections

authors： Cladel NM,Jiang P,Li JJ,Peng X,Cooper TK,Majerciak V,Balogh KK,Meyer TJ,Brendle SA,Budgeon LR,Shearer DA,Munden R,Cam M,Vallur R,Christensen ND,Zheng ZM,Hu J

更新日期：2019-01-01 00:00:00

abstract：:MERS-CoV infection emerged in the Kingdom of Saudi Arabia (KSA) in 2012 and has spread to 26 countries. However, 80% of all cases have occurred in KSA. The largest outbreak outside KSA occurred in South Korea (SK) in 2015. In this report, we describe an epidemiological comparison of the two outbreaks. Data from 1299 c...

journal_title：Emerging microbes & infections

authors： Chen X,Chughtai AA,Dyda A,MacIntyre CR

更新日期：2017-06-07 00:00:00

abstract：:Toxoplasmosis is one of the most common zoonotic diseases in the world. Felines excrete environmentally resistant Toxoplasma gondii oocysts. However, there is no direct evidence to prove tigers are the intermediate host of T. gondii. Here, we show that, IgG antibodies to T. gondii in 80% (8/10) of captive tigers. Two ...

journal_title：Emerging microbes & infections

authors： Yang Y,Dong H,Su R,Jiang N,Li T,Su C,Yuan Z,Zhang L

更新日期：2019-01-01 00:00:00

abstract：:Echinocandin resistance in Candida glabrata poses a serious clinical challenge. The underlying resistance mechanism of a pan-echinocandin-resistant C. glabrata isolate (strain L74) was investigated in this study. FKS mutants carrying specific mutations found in L74 were reconstructed by the Alt-R CRISPR-Cas9 system (F...

journal_title：Emerging microbes & infections

authors： Hou X,Healey KR,Shor E,Kordalewska M,Ortigosa CJ,Paderu P,Xiao M,Wang H,Zhao Y,Lin LY,Zhang YH,Li YZ,Xu YC,Perlin DS,Zhao Y

更新日期：2019-01-01 00:00:00

abstract：:H7N9 influenza viruses emerged in 2013 and have caused severe disease and deaths in humans in China. Some H7N9 viruses circulating in chickens have mutated to highly pathogenic viruses that have caused several disease outbreaks in chickens. Studies have shown that when the H7N9 highly pathogenic viruses replicate in f...

journal_title：Emerging microbes & infections

authors： Yang W,Yin X,Guan L,Li M,Ma S,Shi J,Deng G,Suzuki Y,Chen H

更新日期：2018-09-12 00:00:00

abstract：:Pigs play an important role in interspecies transmission of the influenza virus, particularly as "mixing vessels" for reassortment. Two influenza A/H1N1 virus strains, A/swine/Siberia/1sw/2016 and A/swine/Siberia/4sw/2017, were isolated during a surveillance of pigs from private farms in Russia from 2016 to 2017. Ther...

journal_title：Emerging microbes & infections

authors： Sobolev I,Kurskaya O,Leonov S,Kabilov M,Alikina T,Alekseev A,Yushkov Y,Saito T,Uchida Y,Mine J,Shestopalov A,Sharshov K

更新日期：2019-01-01 00:00:00

abstract：:Influenza has been a long-running health problem and novel antiviral drugs are urgently needed. In pre-clinical studies, we demonstrated broad antiviral activity of D, L-lysine-acetylsalicylate glycine (LASAG) against influenza virus (IV) in cell culture and protection against lethal challenge in mice. LASAG is a comp...

journal_title：Emerging microbes & infections

authors： Scheuch G,Canisius S,Nocker K,Hofmann T,Naumann R,Pleschka S,Ludwig S,Welte T,Planz O

更新日期：2018-03-07 00:00:00

abstract：:The recently emerged novel coronavirus, "severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)", caused a highly contagious disease called coronavirus disease 2019 (COVID-19). The virus was first reported from Wuhan city in China in December, 2019, which in less than three months spread throughout the globe and...

journal_title：Emerging microbes & infections

authors： Lone SA,Ahmad A

更新日期：2020-12-01 00:00:00

abstract：:A novel equine parvovirus, equine parvovirus-hepatitis (EqPV-H), was first discovered in a horse that died of equine serum hepatitis in the USA in 2018. EqPV-H was shown to be a novel etiological agent associated with equine serum hepatitis. Following this initial report, no additional studies on EqPV-H have been publ...

journal_title：Emerging microbes & infections

authors： Lu G,Sun L,Ou J,Xu H,Wu L,Li S

更新日期：2018-10-23 00:00:00

abstract：:Emerging studies have indicated that some penaeidins restrict virus infection; however, the mechanism(s) involved are poorly understood. In the present study, we uncovered that penaeidins are a novel family of antiviral effectors against white spot syndrome virus (WSSV), which antagonize the envelope proteins to block...

journal_title：Emerging microbes & infections

authors： Xiao B,Fu Q,Niu S,Zhu P,He J,Li C

更新日期：2020-12-01 00:00:00

abstract：:Tuberculosis (TB) has been a persistent public health concern for hundreds of years. Despite advances in medicine and science, eliminating this disease has been beyond our reach. Several organizations, including the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Healt...

journal_title：Emerging microbes & infections

authors： Sizemore CF,Schleif AC,Bernstein JB,Heilman CA

更新日期：2012-07-01 00:00:00

abstract：:Candida albicans is a major human fungal pathogen, capable of switching among a range of morphological types, such as the yeast form, including white and opaque cell types and the GUT (gastrointestinally induced transition) cell type, the filamentous form, including hyphal and pseudohyphal cell types, and chlamydospor...

journal_title：Emerging microbes & infections

authors： Liang W,Guan G,Li C,Nobile CJ,Tao L,Huang G

更新日期：2020-02-21 00:00:00

abstract：:A 78-year-old woman with a long-term ankle spacer with antibacterials developed an intra-articular Candida auris infection. Treatment with systemic antifungal therapy plus an amphotericin B moulded cement spacer was successful. ...

journal_title：Emerging microbes & infections

authors： Roberts SC,Zembower TR,Bolon MK,Kadakia AR,Gilley JH,Ko JH,Clark J,Ward-Fore S,Taiwo BO

更新日期：2019-01-01 00:00:00