COVID-19 pandemic - an African perspective.

abstract：:Little is known about the processes that enable influenza A viruses to jump into new host species. Here we show that the non-structural protein1 nucleotide substitution, A374G, encoding the D125G(GAT→GGT) mutation, which evolved during the adaptation of a human virus within a mouse host, activates a novel donor splice...

journal_title：Emerging microbes & infections

authors： Selman M,Dankar SK,Forbes NE,Jia JJ,Brown EG

更新日期：2012-11-01 00:00:00

abstract：:From September 2015 to March 2016, hepatitis A notifications in Germany increased by 45% to 699 cases compared to 482 cases in the same period of the previous year. Children aged five to nine years were predominantly affected (22% of all cases in this period). We hypothesized that this increase could be explained by t...

journal_title：Emerging microbes & infections

authors： Michaelis K,Wenzel JJ,Stark K,Faber M

更新日期：2017-04-26 00:00:00

abstract：:A novel equine parvovirus, equine parvovirus-hepatitis (EqPV-H), was first discovered in a horse that died of equine serum hepatitis in the USA in 2018. EqPV-H was shown to be a novel etiological agent associated with equine serum hepatitis. Following this initial report, no additional studies on EqPV-H have been publ...

journal_title：Emerging microbes & infections

authors： Lu G,Sun L,Ou J,Xu H,Wu L,Li S

更新日期：2018-10-23 00:00:00

abstract：:Echinocandin resistance in Candida glabrata poses a serious clinical challenge. The underlying resistance mechanism of a pan-echinocandin-resistant C. glabrata isolate (strain L74) was investigated in this study. FKS mutants carrying specific mutations found in L74 were reconstructed by the Alt-R CRISPR-Cas9 system (F...

journal_title：Emerging microbes & infections

authors： Hou X,Healey KR,Shor E,Kordalewska M,Ortigosa CJ,Paderu P,Xiao M,Wang H,Zhao Y,Lin LY,Zhang YH,Li YZ,Xu YC,Perlin DS,Zhao Y

更新日期：2019-01-01 00:00:00

abstract：:Occult hepatitis B virus infection (OBI) is a low-level asymptomatic phase of HBV infection. Evidence of OBI clinical relevance is emerging but the mechanisms of its occurrence remain unclear. In this study, the molecular characteristics of 97 confirmed OBI from Chinese blood donors were analyzed and relevant mutation...

journal_title：Emerging microbes & infections

authors： Zhang L,Chang L,Laperche S,Ji H,Zhao J,Jiang X,Wang L,Candotti D

更新日期：2019-01-01 00:00:00

abstract：:Host switch events of influenza A viruses (IAVs) continuously pose a zoonotic threat to humans. In 2013, swine-origin H1N1 IAVs emerged in dogs soon after they were detected in swine in the Guangxi province of China. This host switch was followed by multiple reassortment events between these H1N1 and previously circul...

journal_title：Emerging microbes & infections

authors： Wang G,Dos Anjos Borges LG,Stadlbauer D,Ramos I,Bermúdez González MC,He J,Ding Y,Wei Z,Ouyang K,Huang W,Simon V,Fernandez-Sesma A,Krammer F,Nelson MI,Chen Y,García-Sastre A

更新日期：2019-01-01 00:00:00

abstract：:Shiga toxin-producing Escherichia coli (STEC) are foodborne pathogens causing severe gastroenteritis, which may lead to hemolytic uremic syndrome. The Locus of Enterocyte Effacement (LEE), a Pathogenicity Island (PAI), is a major determinant of intestinal epithelium attachment of a group of STEC strains; however, the ...

journal_title：Emerging microbes & infections

authors： Montero DA,Canto FD,Velasco J,Colello R,Padola NL,Salazar JC,Martin CS,Oñate A,Blanco J,Rasko DA,Contreras C,Puente JL,Scheutz F,Franz E,Vidal RM

更新日期：2019-01-01 00:00:00

abstract：:Acute meningoencephalitis (AME) is associated with considerable morbidity and mortality in children in developing countries. Clinical specimens were collected from children presenting with AME at two Cambodian paediatric hospitals to determine the major aetiologies associated with AME in the country. Cerebrospinal flu...

journal_title：Emerging microbes & infections

authors： Horwood PF,Duong V,Laurent D,Mey C,Sothy H,Santy K,Richner B,Heng S,Hem S,Cheval J,Gorman C,Dussart P,de Jong MD,Kerleguer A,Guillard B,Murgue B,Lecuit M,de Lamballerie X,Farrar JJ,Tarantola A,Eloit M,Buchy P

更新日期：2017-05-24 00:00:00

abstract：:We report the discovery and confirmation of 23 novel mutations with previously undocumented role in isoniazid (INH) drug resistance, in catalase-peroxidase (katG) gene of Mycobacterium tuberculosis (Mtb) isolates. With these mutations, a synonymous mutation in fabG1 (g609a), and two canonical mutations, we were able t...

journal_title：Emerging microbes & infections

authors： Torres JN,Paul LV,Rodwell TC,Victor TC,Amallraja AM,Elghraoui A,Goodmanson AP,Ramirez-Busby SM,Chawla A,Zadorozhny V,Streicher EM,Sirgel FA,Catanzaro D,Rodrigues C,Gler MT,Crudu V,Catanzaro A,Valafar F

更新日期：2015-07-01 00:00:00

abstract：:In March 2013, a patient infected with a novel avian influenza A H7N9 virus was reported in China. Since then, there have been 458 confirmed infection cases and 177 deaths. The virus contains several human-adapted markers, indicating that H7N9 has pandemic potential. The outbreak of this new influenza virus highlighte...

journal_title：Emerging microbes & infections

authors： Leung HC,Chan CC,Poon VK,Zhao HJ,Cheung CY,Ng F,Huang JD,Zheng BJ

更新日期：2015-04-01 00:00:00

abstract：:Toxoplasmosis is one of the most common zoonotic diseases in the world. Felines excrete environmentally resistant Toxoplasma gondii oocysts. However, there is no direct evidence to prove tigers are the intermediate host of T. gondii. Here, we show that, IgG antibodies to T. gondii in 80% (8/10) of captive tigers. Two ...

journal_title：Emerging microbes & infections

authors： Yang Y,Dong H,Su R,Jiang N,Li T,Su C,Yuan Z,Zhang L

更新日期：2019-01-01 00:00:00

abstract：:Dengue virus (DENV) is a mosquito-borne Flavivirus that is endemic in many tropical and sub-tropical countries where the transmission vectors Aedes spp. mosquitoes resides. There are four serotypes of the virus. Each serotype is antigenically different, meaning they elicit heterologous antibodies. Infection with one s...

journal_title：Emerging microbes & infections

authors： Uno N,Ross TM

更新日期：2018-10-10 00:00:00

abstract：:Serology is a crucial part of the public health response to the ongoing SARS-CoV-2 pandemic. Here, we describe the development, validation and clinical evaluation of a protein micro-array as a quantitative multiplex immunoassay that can identify S and N-directed SARS-CoV-2 IgG antibodies with high specificity and sens...

journal_title：Emerging microbes & infections

authors： van Tol S,Mögling R,Li W,Godeke GJ,Swart A,Bergmans B,Brandenburg A,Kremer K,Murk JL,van Beek J,Wintermans B,Reimerink J,Bosch BJ,Reusken C

更新日期：2020-12-01 00:00:00

abstract：:Since the outbreak of coronavirus disease 2019 (COVID-19) in Wuhan, China, it has rapidly spread across many other countries. While the majority of patients were considered mild, critically ill patients involving respiratory failure and multiple organ dysfunction syndrome are not uncommon, which could result death. We...

journal_title：Emerging microbes & infections

authors： Han H,Ma Q,Li C,Liu R,Zhao L,Wang W,Zhang P,Liu X,Gao G,Liu F,Jiang Y,Cheng X,Zhu C,Xia Y

更新日期：2020-12-01 00:00:00

abstract：:Candida albicans is a major human fungal pathogen, capable of switching among a range of morphological types, such as the yeast form, including white and opaque cell types and the GUT (gastrointestinally induced transition) cell type, the filamentous form, including hyphal and pseudohyphal cell types, and chlamydospor...

journal_title：Emerging microbes & infections

authors： Liang W,Guan G,Li C,Nobile CJ,Tao L,Huang G

更新日期：2020-02-21 00:00:00

abstract：:Tuberculosis (TB) has been a persistent public health concern for hundreds of years. Despite advances in medicine and science, eliminating this disease has been beyond our reach. Several organizations, including the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Healt...

journal_title：Emerging microbes & infections

authors： Sizemore CF,Schleif AC,Bernstein JB,Heilman CA

更新日期：2012-07-01 00:00:00

abstract：:Babesiosis is a tick-borne, zoonotic disease caused by Babesia spp. Two cases of babesiosis were detected by nested polymerase chain reaction (PCR) in Yunnan province, China, and further confirmed by molecular assay. The blood smears showed intraerythrocytic ring form and tetrads typical of small B. microti. In both c...

journal_title：Emerging microbes & infections

authors： Zhou X,Li SG,Wang JZ,Huang JL,Zhou HJ,Chen JH,Zhou XN

更新日期：2014-08-01 00:00:00

abstract：:Tigecycline is regarded as a last-resort treatment for carbapenem-resistant Enterobacteriaceae (CRE), however, the emergence of tigecycline heteroresistance has posted the therapeutic challenge to combat this "nightmare bacteria". The primary purpose of this study was to demonstrate the existence of tigecycline hetero...

journal_title：Emerging microbes & infections

authors： Liu H,Jia X,Zou H,Sun S,Li S,Wang Y,Xia Y

更新日期：2019-01-01 00:00:00

abstract：:The first imported case of Middle East respiratory syndrome (MERS) in China recently occurred, allowing for the characterization of antibody titers in a series of the patient's sera using the following methods based on recombinant viral structural antigens: inactivated MERS coronavirus (MERS-CoV) enzyme-linked immunos...

journal_title：Emerging microbes & infections

authors： Wang W,Wang H,Deng Y,Song T,Lan J,Wu G,Ke C,Tan W

更新日期：2016-11-09 00:00:00

abstract：:Hepatitis C virus (HCV) infection is a major cause of chronic hepatitis and liver cancer worldwide. Adaptive mutations play important roles in the development of the HCV replicon and its infectious clones. We and others have previously identified the p7 mutation F772S and the co-presence of NS4A mutations in infectiou...

journal_title：Emerging microbes & infections

authors： Duan X,Anwar MI,Xu Z,Ma L,Yuan G,Chen Y,Liu X,Xia J,Zhou Y,Li YP

更新日期：2018-08-08 00:00:00

abstract：:Avian influenza A(H7N9) virus (A(H7N9)) emerged in February 2013. Liver impairment of unknown cause is present in 29% of patients with A(H7N9) infection, some of whom experience severe liver injury. Hypoxic hepatitis (HH) is a type of acute severe liver injury characterized by an abrupt, massive increase in serum amin...

journal_title：Emerging microbes & infections

authors： Zhang Y,Liu J,Yu L,Zhou N,Ding W,Zheng S,Shi D,Li L

更新日期：2016-01-06 00:00:00

abstract：:Pigs play an important role in interspecies transmission of the influenza virus, particularly as "mixing vessels" for reassortment. Two influenza A/H1N1 virus strains, A/swine/Siberia/1sw/2016 and A/swine/Siberia/4sw/2017, were isolated during a surveillance of pigs from private farms in Russia from 2016 to 2017. Ther...

journal_title：Emerging microbes & infections

authors： Sobolev I,Kurskaya O,Leonov S,Kabilov M,Alikina T,Alekseev A,Yushkov Y,Saito T,Uchida Y,Mine J,Shestopalov A,Sharshov K

更新日期：2019-01-01 00:00:00

abstract：:Influenza viruses of the H4 subtype are widespread in wild birds, circulate in domestic poultry, readily infect mammals, and tolerate the insertion of a polybasic cleavage site. In addition, serological evidence suggests that humans working with poultry are exposed to these viruses. While H4 viruses are not of immedia...

journal_title：Emerging microbes & infections

authors： Amanat F,Meade P,Strohmeier S,Krammer F

更新日期：2019-01-01 00:00:00

abstract：:Emerging studies have indicated that some penaeidins restrict virus infection; however, the mechanism(s) involved are poorly understood. In the present study, we uncovered that penaeidins are a novel family of antiviral effectors against white spot syndrome virus (WSSV), which antagonize the envelope proteins to block...

journal_title：Emerging microbes & infections

authors： Xiao B,Fu Q,Niu S,Zhu P,He J,Li C

更新日期：2020-12-01 00:00:00

abstract：:Highly pathogenic avian influenza H5N1 viruses were first isolated in Bangladesh in February 2007. Subsequently, clades 2.2.2, 2.3.4.2 and 2.3.2.1a were identified in Bangladesh, and our previous surveillance data revealed that by the end of 2014, the circulating viruses exclusively comprised clade 2.3.2.1a. We recent...

journal_title：Emerging microbes & infections

authors： Barman S,Marinova-Petkova A,Hasan MK,Akhtar S,El-Shesheny R,Turner JC,Franks J,Walker D,Seiler J,Friedman K,Kercher L,Jeevan T,Darnell D,Kayali G,Jones-Engel L,McKenzie P,Krauss S,Webby RJ,Webster RG,Feeroz MM

更新日期：2017-08-09 00:00:00

abstract：:Background: The COVID-19 pandemic represents an unprecedented global challenge and implicates a wide range of burden on medical professionals. Here, we evaluated the perception of the COVID-19 pandemic among medical professionals in Germany. Methods: A total of n = 2827 medical professionals participated in an online ...

journal_title：Emerging microbes & infections

authors： Paffenholz P,Peine A,Hellmich M,Paffenholz SV,Martin L,Luedde M,Haverkamp M,Roderburg C,Marx G,Heidenreich A,Trautwein C,Luedde T,Loosen SH

更新日期：2020-12-01 00:00:00

abstract：:Recent canine influenza outbreaks have raised concerns about the generation of pathogenic variants that may pose a threat to public health. Here, we examine avian-like H3N2 canine influenza viruses (CIVs) isolated from 2009 to 2013 in South Korea from dogs. Phylogenetic analysis revealed that these viruses are closely...

journal_title：Emerging microbes & infections

authors： Lee IW,Kim YI,Lim GJ,Kwon HI,Si YJ,Park SJ,Kim EH,Kim SM,Nguyen HD,Song MS,Choi YK

更新日期：2018-03-07 00:00:00

abstract：:Histoplasmosis caused by the fungus Histoplasma capsulatum is often lethal in patients with AIDS. Urine antigen testing is highly sensitive and much quicker for diagnosis than culture. Histoplasmosis has a patchy and incompletely appreciated distribution around the world especially in South East Asia. We conducted a s...

journal_title：Emerging microbes & infections

authors： Baker J,Setianingrum F,Wahyuningsih R,Denning DW

更新日期：2019-01-01 00:00:00

abstract：:Nontuberculous mycobacterial (NTM) infections in humans have increased in prevalence in recent decades. Mycobacterium kansasii is one of the most prevalent human pathogenic NTM species worldwide. Herein, we report the first isolation of M. kansasii from an indoor domestic cat in Japan. Comparative genome sequence anal...

journal_title：Emerging microbes & infections

authors： Fukano H,Terazono T,Hirabayashi A,Yoshida M,Suzuki M,Wada S,Ishii N,Hoshino Y

更新日期：2021-01-19 00:00:00

abstract：:Interferon-induced transmembrane protein 3 (IFITM3) as an antiviral factor can inhibit replication of several viruses including influenza virus. A single-nucleotide polymorphism rs12252-C of IFITM3 results in a truncated IFITM3 protein lacking its first 21 amino acids, which is much higher in the Han Chinese populatio...

journal_title：Emerging microbes & infections

authors： Lei N,Li Y,Sun Q,Lu J,Zhou J,Li Z,Liu L,Guo J,Qin K,Wang H,Zhao J,Li C,Sun L,Wang D,Zhao Z,Shu Y

更新日期：2020-12-01 00:00:00