Abstract:
:Pigs play an important role in interspecies transmission of the influenza virus, particularly as "mixing vessels" for reassortment. Two influenza A/H1N1 virus strains, A/swine/Siberia/1sw/2016 and A/swine/Siberia/4sw/2017, were isolated during a surveillance of pigs from private farms in Russia from 2016 to 2017. There was a 10% identity difference between the HA and NA nucleotide sequences of isolated strains and the most phylogenetically related sequences (human influenza viruses of 1980s). Simultaneously, genome segments encoding internal proteins were found to be phylogenetically related to the A/H1N1pdm09 influenza virus. In addition, two amino acids (129-130) were deleted in the HA of A/swine/Siberia/4sw/2017 compared to that of A/swine/Siberia/1sw/2016 HA.
journal_name
Emerg Microbes Infectjournal_title
Emerging microbes & infectionsauthors
Sobolev I,Kurskaya O,Leonov S,Kabilov M,Alikina T,Alekseev A,Yushkov Y,Saito T,Uchida Y,Mine J,Shestopalov A,Sharshov Kdoi
10.1080/22221751.2019.1673136subject
Has Abstractpub_date
2019-01-01 00:00:00pages
1456-1464issue
1issn
2222-1751journal_volume
8pub_type
杂志文章abstract::Norovirus (NoV) is now recognized as a leading cause of nonbacterial acute gastroenteritis; however, the NoV GII.17 genotype has rarely been reported as the predominant genotype in clinical diarrhea cases. During the winter of 2014–2015, the GII.17 genotype, together with the NoV GII.4 genotype, dominated in sporadic ...
journal_title:Emerging microbes & infections
pub_type: 杂志文章
doi:10.1038/emi.2015.67
更新日期:2015-11-01 00:00:00
abstract::In March 2013, a patient infected with a novel avian influenza A H7N9 virus was reported in China. Since then, there have been 458 confirmed infection cases and 177 deaths. The virus contains several human-adapted markers, indicating that H7N9 has pandemic potential. The outbreak of this new influenza virus highlighte...
journal_title:Emerging microbes & infections
pub_type: 杂志文章
doi:10.1038/emi.2015.22
更新日期:2015-04-01 00:00:00
abstract::Emerging studies have indicated that some penaeidins restrict virus infection; however, the mechanism(s) involved are poorly understood. In the present study, we uncovered that penaeidins are a novel family of antiviral effectors against white spot syndrome virus (WSSV), which antagonize the envelope proteins to block...
journal_title:Emerging microbes & infections
pub_type: 杂志文章
doi:10.1080/22221751.2020.1729068
更新日期:2020-12-01 00:00:00
abstract::Previous studies have shown that livestock (LA)-MRSA ST398 evolved from a human-adapted methicillin-susceptible S. aureus (MSSA) clone. However, detailed information regarding ST9 is still unclear. Here, we characterized a community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) ST9-SCCmec XII isolat...
journal_title:Emerging microbes & infections
pub_type: 杂志文章
doi:10.1080/22221751.2020.1848354
更新日期:2020-12-01 00:00:00
abstract::Zika virus (ZIKV) has become a threat to global health since the outbreak in Brazil in 2015. Although ZIKV is generally considered an Aedes-transmitted pathogen, new evidence has shown that parts of the virus closely resemble Culex-transmitted viruses. Therefore, it is important to evaluate the competence of Culex spe...
journal_title:Emerging microbes & infections
pub_type: 杂志文章
doi:10.1038/emi.2016.102
更新日期:2016-09-07 00:00:00
abstract::Nontuberculous mycobacterial (NTM) infections in humans have increased in prevalence in recent decades. Mycobacterium kansasii is one of the most prevalent human pathogenic NTM species worldwide. Herein, we report the first isolation of M. kansasii from an indoor domestic cat in Japan. Comparative genome sequence anal...
journal_title:Emerging microbes & infections
pub_type: 信件
doi:10.1080/22221751.2021.1878935
更新日期:2021-01-19 00:00:00
abstract::Background: The COVID-19 pandemic represents an unprecedented global challenge and implicates a wide range of burden on medical professionals. Here, we evaluated the perception of the COVID-19 pandemic among medical professionals in Germany. Methods: A total of n = 2827 medical professionals participated in an online ...
journal_title:Emerging microbes & infections
pub_type: 杂志文章
doi:10.1080/22221751.2020.1785951
更新日期:2020-12-01 00:00:00
abstract::We conducted this study to describe the dynamics of the acquisition of respiratory pathogens, their potential interactions and risk factors for possible lower respiratory tract infection symptoms (LRTI) among French pilgrims during the 2018 Hajj. Each participant underwent four successive systematic nasopharyngeal swa...
journal_title:Emerging microbes & infections
pub_type: 杂志文章
doi:10.1080/22221751.2019.1693247
更新日期:2019-01-01 00:00:00
abstract::Molecular epidemiology of Clostridium difficile infection (CDI) has been extensively studied in North America and Europe; however, limited data on CDI are available in the Asia-Pacific region. A multicentre retrospective study was conducted in this region. C. difficile isolates were subjected to multilocus sequence ty...
journal_title:Emerging microbes & infections
pub_type: 杂志文章
doi:10.1080/22221751.2019.1682472
更新日期:2019-01-01 00:00:00
abstract::Worldwide emergence of Salmonella enterica serovar Newport (S. Newport) infection in humans, in parallel with a significant increasing prevalence of antimicrobial resistance (AR), is a serious public health concern. However, the prevalence of S. Newport resistance in China remains largely unknown. A retrospective stud...
journal_title:Emerging microbes & infections
pub_type: 信件
doi:10.1080/22221751.2020.1733439
更新日期:2020-03-03 00:00:00
abstract::MERS-CoV infection emerged in the Kingdom of Saudi Arabia (KSA) in 2012 and has spread to 26 countries. However, 80% of all cases have occurred in KSA. The largest outbreak outside KSA occurred in South Korea (SK) in 2015. In this report, we describe an epidemiological comparison of the two outbreaks. Data from 1299 c...
journal_title:Emerging microbes & infections
pub_type: 杂志文章
doi:10.1038/emi.2017.40
更新日期:2017-06-07 00:00:00
abstract::Severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) has resulted in a pandemic and is continuing to spread rapidly around the globe. No effective vaccine is currently available to prevent COVID-19, and intense efforts are being invested worldwide into vaccine development. In this context, all technolo...
journal_title:Emerging microbes & infections
pub_type: 杂志文章
doi:10.1080/22221751.2020.1791737
更新日期:2020-12-01 00:00:00
abstract::Shiga toxin (Stx)-producing Escherichia coli (STEC) can cause a wide range of symptoms from asymptomatic carriage, mild diarrhea to bloody diarrhea (BD) and hemolytic uremic syndrome (HUS). Intimin, encoded by the eae gene, also plays a critical role in STEC pathogenesis. Herein, we investigated the prevalence and gen...
journal_title:Emerging microbes & infections
pub_type: 杂志文章
doi:10.1080/22221751.2020.1850182
更新日期:2020-12-01 00:00:00
abstract::Zika virus (ZIKV) infection during pregnancy is associated with congenital brain abnormalities, a finding that highlights the urgent need to understand mother-to-fetus transmission mechanisms. Human umbilical cord mesenchymal stem cells (hUCMSCs) are susceptible to ZIKV infection but the underlying mechanisms of viral...
journal_title:Emerging microbes & infections
pub_type: 杂志文章
doi:10.1080/22221751.2020.1821581
更新日期:2020-12-01 00:00:00
abstract::Interleukin 17 (IL-17) and its closest relative, IL-17F, have recently drawn much attention in the field of immunology. IL-17 and IL-17F are expressed by a distinct type of T cells, T helper 17 cells and certain other lymphocytes. These cytokines play key regulatory roles in host defense and inflammatory diseases. In ...
journal_title:Emerging microbes & infections
pub_type: 杂志文章,评审
doi:10.1038/emi.2013.58
更新日期:2013-09-01 00:00:00
abstract::GRP78/BiP is an endoplasmic reticulum (ER) chaperone protein with the important function of maintaining ER homeostasis, and the overexpression of GRP78/BiP alleviates ER stress. Our previous studies showed that infection with enterovirus 71 (EV71), a (+)RNA picornavirus, induced GRP78/BiP upregulation; however, ectopi...
journal_title:Emerging microbes & infections
pub_type: 杂志文章
doi:10.1038/emi.2016.20
更新日期:2016-03-23 00:00:00
abstract::Monoclonal antibodies (mAbs), which currently constitute the main class of biotherapeutics, are now recognized as major medical tools that are increasingly being considered to fight severe viral infections. Indeed, the number of antiviral mAbs developed in recent years has grown exponentially. Although their direct ef...
journal_title:Emerging microbes & infections
pub_type: 杂志文章,评审
doi:10.1038/emi.2016.97
更新日期:2016-08-17 00:00:00
abstract::Saffold virus (SAFV), a newly discovered human cardiovirus of the Picornaviridae family, causes widespread infection among children, as shown by previous seroprevalence studies. To determine the host cell range of SAFV and its cytopathogenicity, eight mammalian cell lines that were available in the laboratory were scr...
journal_title:Emerging microbes & infections
pub_type: 杂志文章
doi:10.1038/emi.2014.15
更新日期:2014-02-01 00:00:00
abstract::A novel equine parvovirus, equine parvovirus-hepatitis (EqPV-H), was first discovered in a horse that died of equine serum hepatitis in the USA in 2018. EqPV-H was shown to be a novel etiological agent associated with equine serum hepatitis. Following this initial report, no additional studies on EqPV-H have been publ...
journal_title:Emerging microbes & infections
pub_type: 杂志文章
doi:10.1038/s41426-018-0174-2
更新日期:2018-10-23 00:00:00
abstract::Unlike those infected by H5N1, birds infected by the newly discovered H7N9 virus have no observable clinical symptoms. Public health workers in China do not know where the public health threat lies. In this study, we used a distributed focused crawler to analyze online knowledge of the live bird trade in first-wave pr...
journal_title:Emerging microbes & infections
pub_type: 杂志文章
doi:10.1038/emi.2013.91
更新日期:2013-12-01 00:00:00
abstract::Interferon-induced transmembrane protein 3 (IFITM3) as an antiviral factor can inhibit replication of several viruses including influenza virus. A single-nucleotide polymorphism rs12252-C of IFITM3 results in a truncated IFITM3 protein lacking its first 21 amino acids, which is much higher in the Han Chinese populatio...
journal_title:Emerging microbes & infections
pub_type: 杂志文章
doi:10.1080/22221751.2020.1756696
更新日期:2020-12-01 00:00:00
abstract::Human enteroviruses frequently cause severe diseases in children. Human enteroviruses are transmitted via the fecal-oral route and respiratory droplets, and primary replication occurs in the gastro-intestinal and respiratory tracts; however, how enteroviruses infect these sites is largely unknown. Human intestinal org...
journal_title:Emerging microbes & infections
pub_type: 杂志文章
doi:10.1038/s41426-018-0077-2
更新日期:2018-05-09 00:00:00
abstract::COVID-19, the worst pandemic in 100 years, has rapidly spread to the entire world in 2 months since its early report in January 2020. Based on the publicly available data sources, we developed a simple mathematic modeling approach to track the outbreaks of COVID-19 in the US and three selected states: New York, Michig...
journal_title:Emerging microbes & infections
pub_type: 信件
doi:10.1080/22221751.2020.1760146
更新日期:2020-12-01 00:00:00
abstract::The three unprecedented outbreaks of emerging human coronavirus (HCoV) infections at the beginning of the twenty-first century have highlighted the necessity for readily available, accurate and fast diagnostic testing methods. The laboratory diagnostic methods for human coronavirus infections have evolved substantiall...
journal_title:Emerging microbes & infections
pub_type: 杂志文章,评审
doi:10.1080/22221751.2020.1745095
更新日期:2020-12-01 00:00:00
abstract::Avian influenza A(H7N9) virus (A(H7N9)) emerged in February 2013. Liver impairment of unknown cause is present in 29% of patients with A(H7N9) infection, some of whom experience severe liver injury. Hypoxic hepatitis (HH) is a type of acute severe liver injury characterized by an abrupt, massive increase in serum amin...
journal_title:Emerging microbes & infections
pub_type: 杂志文章
doi:10.1038/emi.2016.1
更新日期:2016-01-06 00:00:00
abstract::Human papillomaviruses (HPV) contribute to most cervical cancers and are considered to be sexually transmitted. However, papillomaviruses are often found in cancers of internal organs, including the stomach, raising the question as to how the viruses gain access to these sites. A possible connection between blood tran...
journal_title:Emerging microbes & infections
pub_type: 杂志文章
doi:10.1080/22221751.2019.1637072
更新日期:2019-01-01 00:00:00
abstract::Serology detection is recognized for its sensitivity in convalescent patients with COVID-19, in comparison with nucleic acid amplification tests (NAATs). This article aimed to evaluate the diagnostic accuracy of serologic methods for COVID-19 based on assay design and post-symptom-onset intervals. Two authors independ...
journal_title:Emerging microbes & infections
pub_type: 杂志文章,meta分析
doi:10.1080/22221751.2020.1826362
更新日期:2020-12-01 00:00:00
abstract::A 78-year-old woman with a long-term ankle spacer with antibacterials developed an intra-articular Candida auris infection. Treatment with systemic antifungal therapy plus an amphotericin B moulded cement spacer was successful. ...
journal_title:Emerging microbes & infections
pub_type: 杂志文章
doi:10.1080/22221751.2019.1625287
更新日期:2019-01-01 00:00:00
abstract::Acute meningoencephalitis (AME) is associated with considerable morbidity and mortality in children in developing countries. Clinical specimens were collected from children presenting with AME at two Cambodian paediatric hospitals to determine the major aetiologies associated with AME in the country. Cerebrospinal flu...
journal_title:Emerging microbes & infections
pub_type: 杂志文章
doi:10.1038/emi.2017.15
更新日期:2017-05-24 00:00:00
abstract::Whooping cough, caused by Bordetella pertussis, has resurged and presents a global health burden worldwide. B. pertussis strains unable to produce the acellular pertussis vaccine component pertactin (Prn), have been emerging and in some countries represent up to 95% of recent clinical isolates. Knowledge on the effect...
journal_title:Emerging microbes & infections
pub_type: 杂志文章
doi:10.1038/s41426-018-0039-8
更新日期:2018-03-21 00:00:00