Abstract:
:Worldwide emergence of Salmonella enterica serovar Newport (S. Newport) infection in humans, in parallel with a significant increasing prevalence of antimicrobial resistance (AR), is a serious public health concern. However, the prevalence of S. Newport resistance in China remains largely unknown. A retrospective study of 287 S. Newport clinical isolates collected during 1997-2018 was undertaken for characterization of AR profiles using the micro-dilution assay. We found a recent emergence of colistin resistance in four Chinese clinical isolates, including mcr-1-positive isolates. Importantly, phylogenomic and microbiological investigations indicate multiple independent clonal transmission of colistin-resistant S. Newport isolates of different seafood origins. Our study highlights potential reservoirs for transmission of colistin resistance and suggests that the global food supply chain may facilitate this dissemination.
journal_name
Emerg Microbes Infectjournal_title
Emerging microbes & infectionsauthors
Elbediwi M,Pan H,Biswas S,Li Y,Yue Mdoi
10.1080/22221751.2020.1733439subject
Has Abstractpub_date
2020-03-03 00:00:00pages
535-538issue
1issn
2222-1751journal_volume
9pub_type
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journal_title:Emerging microbes & infections
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journal_title:Emerging microbes & infections
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abstract::Pyrazinamide (PZA) is a key antibiotic in current anti-tuberculosis regimens. Although the WHO has stressed the urgent need to obtain data on PZA resistance, in high tuberculosis burden countries, little is known about the level of PZA resistance, the genetic basis of such resistance or its link with Mycobacterium tub...
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journal_title:Emerging microbes & infections
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pub_type: 杂志文章,多中心研究,随机对照试验
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journal_title:Emerging microbes & infections
pub_type: 杂志文章,评审
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journal_title:Emerging microbes & infections
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