Emerging colistin resistance in Salmonella enterica serovar Newport isolates from human infections.

Abstract:

:Worldwide emergence of Salmonella enterica serovar Newport (S. Newport) infection in humans, in parallel with a significant increasing prevalence of antimicrobial resistance (AR), is a serious public health concern. However, the prevalence of S. Newport resistance in China remains largely unknown. A retrospective study of 287 S. Newport clinical isolates collected during 1997-2018 was undertaken for characterization of AR profiles using the micro-dilution assay. We found a recent emergence of colistin resistance in four Chinese clinical isolates, including mcr-1-positive isolates. Importantly, phylogenomic and microbiological investigations indicate multiple independent clonal transmission of colistin-resistant S. Newport isolates of different seafood origins. Our study highlights potential reservoirs for transmission of colistin resistance and suggests that the global food supply chain may facilitate this dissemination.

journal_name

Emerg Microbes Infect

authors

Elbediwi M,Pan H,Biswas S,Li Y,Yue M

doi

10.1080/22221751.2020.1733439

subject

Has Abstract

pub_date

2020-03-03 00:00:00

pages

535-538

issue

1

issn

2222-1751

journal_volume

9

pub_type

信件
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