Abstract：
:Functional studies on heteroantisera raised against mouse B cells in rabbits suggest a correlation between thymus-independent B cells and LPS-responsive B cells, and differences in either from thymus-dependent B cells. Furthermore it seems possible to follow B-lymphocyte differentiation from antigen-uncommitted precursors to antigen committed immature B cells to mature B lymphocytes by the loss and acquisition of surface markers distinguished by these heteroantisera. Additional evidence is provided that there are distinctive antigenic differences between antibody forming cells raised from the same B-cell source after in vivo or in vitro immunization.
journal_name
Immunologyjournal_title
Immunologyauthors
Gorczynski RMsubject
Has Abstractpub_date
1977-05-01 00:00:00pages
717-29issue
5eissn
0019-2805issn
1365-2567journal_volume
32pub_type
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