Critical slowing down as a biomarker for seizure susceptibility.

abstract：:The nitrogen-vacancy (NV) centre in diamond is a promising candidate for a solid-state qubit. However, its charge state is known to be unstable, discharging from the qubit state NV(-) into the neutral state NV(0) under various circumstances. Here we demonstrate that the charge state can be controlled by an electrolyti...

journal_title：Nature communications

authors： Grotz B,Hauf MV,Dankerl M,Naydenov B,Pezzagna S,Meijer J,Jelezko F,Wrachtrup J,Stutzmann M,Reinhard F,Garrido JA

更新日期：2012-03-06 00:00:00

abstract：:Nanoscale dimensions in materials lead to unique electronic and structural properties with applications ranging from site-specific drug delivery to anodes for lithium-ion batteries. These functional properties often involve large-amplitude strains and structural modifications, and thus require an understanding of the ...

journal_title：Nature communications

authors： Szilagyi E,Wittenberg JS,Miller TA,Lutker K,Quirin F,Lemke H,Zhu D,Chollet M,Robinson J,Wen H,Sokolowski-Tinten K,Lindenberg AM

更新日期：2015-03-12 00:00:00

abstract：:Three-dimensional graphene network is a promising structure for improving both the mechanical properties and functional capabilities of reinforced polymer and ceramic matrix composites. However, direct application in a metal matrix remains difficult due to the reason that wetting is usually unfavorable in the carbon/m...

journal_title：Nature communications

authors： Zhang X,Xu Y,Wang M,Liu E,Zhao N,Shi C,Lin D,Zhu F,He C

更新日期：2020-06-02 00:00:00

abstract：:The c-Jun/AP-1 transcription factor controls key cellular behaviours, including proliferation and apoptosis, in response to JNK and Ras/MAPK signalling. While the JNK pathway has been well characterized, the mechanism of activation by Ras was elusive. Here we identify the uncharacterized ubiquitin ligase Trim7 as a cr...

journal_title：Nature communications

authors： Chakraborty A,Diefenbacher ME,Mylona A,Kassel O,Behrens A

更新日期：2015-04-08 00:00:00

abstract：:The metazoan TREX complex is recruited to mRNA during nuclear RNA processing and functions in exporting mRNA to the cytoplasm. Nxf1 is an mRNA export receptor, which binds processed mRNA and transports it through the nuclear pore complex. At present, the relationship between TREX and Nxf1 is not understood. Here we sh...

journal_title：Nature communications

authors： Viphakone N,Hautbergue GM,Walsh M,Chang CT,Holland A,Folco EG,Reed R,Wilson SA

更新日期：2012-01-01 00:00:00

abstract：:Protein function and dynamics are closely related; however, accurate dynamics information is difficult to obtain. Here based on a carefully assembled data set derived from experimental data for proteins in solution, we quantify backbone dynamics properties on the amino-acid level and develop DynaMine--a fast, high-qua...

journal_title：Nature communications

authors： Cilia E,Pancsa R,Tompa P,Lenaerts T,Vranken WF

更新日期：2013-01-01 00:00:00

abstract：:Detection of microbial components such as lipopolysaccharide (LPS) by Toll-like receptor 4 (TLR4) on macrophages induces a robust pro-inflammatory response that is dependent on metabolic reprogramming. These innate metabolic changes have been compared to aerobic glycolysis in tumour cells. However, the mechanisms by w...

journal_title：Nature communications

authors： Balic JJ,Albargy H,Luu K,Kirby FJ,Jayasekara WSN,Mansell F,Garama DJ,De Nardo D,Baschuk N,Louis C,Humphries F,Fitzgerald K,Latz E,Gough DJ,Mansell A

更新日期：2020-07-30 00:00:00

abstract：:Compartmentalization of the gut microbiota is thought to be important to system function, but the extent of spatial organization in the gut ecosystem remains poorly understood. Here, we profile the murine colonic microbiota along longitudinal and lateral axes using laser capture microdissection. We found fine-scale sp...

journal_title：Nature communications

authors： Riva A,Kuzyk O,Forsberg E,Siuzdak G,Pfann C,Herbold C,Daims H,Loy A,Warth B,Berry D

更新日期：2019-09-25 00:00:00

abstract：:Plant metacaspases mediate programmed cell death in development, biotic and abiotic stresses, damage-induced immune response, and resistance to pathogen attack. Most metacaspases require Ca2+ for their activation and substrate processing. However, the Ca2+-dependent activation mechanism remains elusive. Here we report...

journal_title：Nature communications

authors： Zhu P,Yu XH,Wang C,Zhang Q,Liu W,McSweeney S,Shanklin J,Lam E,Liu Q

更新日期：2020-05-07 00:00:00

abstract：:To fulfill its role in protein biogenesis, the endoplasmic reticulum (ER) depends on the Hsp70-type molecular chaperone BiP, which requires a constant ATP supply. However, the carrier that catalyzes ATP uptake into the ER was unknown. Here, we report that our screen of gene expression datasets for member(s) of the fam...

journal_title：Nature communications

authors： Klein MC,Zimmermann K,Schorr S,Landini M,Klemens PAW,Altensell J,Jung M,Krause E,Nguyen D,Helms V,Rettig J,Fecher-Trost C,Cavalié A,Hoth M,Bogeski I,Neuhaus HE,Zimmermann R,Lang S,Haferkamp I

更新日期：2018-08-28 00:00:00

abstract：:Charge-to-spin conversion in various materials is the key for the fundamental understanding of spin-orbitronics and efficient magnetization manipulation. Here we report the direct spatial imaging of current-induced spin accumulation at the channel edges of Bi2Se3 and BiSbTeSe2 topological insulators as well as Pt by a...

journal_title：Nature communications

authors： Liu Y,Besbas J,Wang Y,He P,Chen M,Zhu D,Wu Y,Lee JM,Wang L,Moon J,Koirala N,Oh S,Yang H

更新日期：2018-06-27 00:00:00

abstract：:RNA silencing inhibits mRNA translation. While mRNA translation accounts for the majority of cellular energy expenditure, it is unclear if RNA silencing regulates energy homeostasis. Here, we report that hepatic Argonaute 2 (Ago2)-mediated RNA silencing regulates both intrinsic energy production and consumption and di...

journal_title：Nature communications

authors： Zhang C,Seo J,Murakami K,Salem ESB,Bernhard E,Borra VJ,Choi K,Yuan CL,Chan CC,Chen X,Huang T,Weirauch MT,Divanovic S,Qi NR,Thomas HE,Mercer CA,Siomi H,Nakamura T

更新日期：2018-09-10 00:00:00

abstract：:Iron sequestration by host proteins contributes to the defence against bacterial pathogens, which need iron for their metabolism and virulence. A Pseudomonas aeruginosa mutant lacking all three known iron acquisition systems retains the ability to grow in media containing iron chelators, suggesting the presence of add...

journal_title：Nature communications

authors： Lin J,Zhang W,Cheng J,Yang X,Zhu K,Wang Y,Wei G,Qian PY,Luo ZQ,Shen X

更新日期：2017-03-28 00:00:00

abstract：:To cope with the global bacterial multidrug resistance, scientific communities have devoted significant efforts to develop novel antibiotics, particularly those with new modes of actions. Teixobactin, recently isolated from uncultured bacteria, is considered as a promising first-in-class drug candidate for clinical de...

journal_title：Nature communications

authors： Jin K,Sam IH,Po KHL,Lin D,Ghazvini Zadeh EH,Chen S,Yuan Y,Li X

更新日期：2016-08-03 00:00:00

abstract：:Hidden hearing loss (HHL) is a recently described auditory neuropathy believed to contribute to speech discrimination and intelligibility deficits in people with normal audiological tests. Animals and humans with HHL have normal auditory thresholds but defective cochlear neurotransmission, that is, reduced suprathresh...

journal_title：Nature communications

authors： Wan G,Corfas G

更新日期：2017-02-17 00:00:00

abstract：:Soil bacterial diversity varies across biomes with potential impacts on soil ecological functioning. Here, we incorporate key factors that affect soil bacterial abundance and diversity across spatial scales into a mechanistic modeling framework considering soil type, carbon inputs and climate towards predicting soil b...

journal_title：Nature communications

authors： Bickel S,Or D

更新日期：2020-01-08 00:00:00

abstract：:Systems allowing label-free molecular detection are expected to have enormous impact on biochemical sciences. Research focuses on materials and technologies based on exploiting localized surface plasmon resonances in metallic nanostructures. The reason for this focused attention is their suitability for single-molecul...

journal_title：Nature communications

authors： Maccaferri N,Gregorczyk KE,de Oliveira TV,Kataja M,van Dijken S,Pirzadeh Z,Dmitriev A,Åkerman J,Knez M,Vavassori P

更新日期：2015-02-02 00:00:00

abstract：:Exploitation of the oxidation behaviour in an environmentally sensitive semiconductor is significant to modulate its electronic properties and develop unique applications. Here, we demonstrate a native oxidation-inspired InSe field-effect transistor as an artificial synapse in device level that benefits from the boost...

journal_title：Nature communications

authors： Yang FS,Li M,Lee MP,Ho IY,Chen JY,Ling H,Li Y,Chang JK,Yang SH,Chang YM,Lee KC,Chou YC,Ho CH,Li W,Lien CH,Lin YF

更新日期：2020-06-12 00:00:00

abstract：:X-linked lymphoproliferative syndrome type-2 (XLP-2) is a primary immunodeficiency disease attributed to XIAP mutation and is triggered by infection. Here, we show that mouse Xiap-/- regulatory T (Treg) cells and human XIAP-deficient Treg cells are defective in suppressive function. The Xiap-/- Treg cell defect is lin...

journal_title：Nature communications

authors： Hsieh WC,Hsu TS,Chang YJ,Lai MZ

更新日期：2018-01-31 00:00:00

abstract：:Inflammation and thrombosis occur together in many diseases. The leukocyte integrin Mac-1 (also known as integrin αMβ2, or CD11b/CD18) is crucial for leukocyte recruitment to the endothelium, and Mac-1 engagement of platelet GPIbα is required for injury responses in diverse disease models. However, the role of Mac-1 i...

journal_title：Nature communications

authors： Wang Y,Gao H,Shi C,Erhardt PW,Pavlovsky A,A Soloviev D,Bledzka K,Ustinov V,Zhu L,Qin J,Munday AD,Lopez J,Plow E,Simon DI

更新日期：2017-05-30 00:00:00

abstract：:Shear-wave anisotropy in Earth's mantle helps constrain the lattice-preferred orientation of anisotropic minerals due to viscous flow. Previous studies at the Japan Trench subduction zone using land-based seismic networks identified strong anisotropy in the mantle wedge, reflecting viscous flow induced by the subducti...

journal_title：Nature communications

authors： Uchida N,Nakajima J,Wang K,Takagi R,Yoshida K,Nakayama T,Hino R,Okada T,Asano Y

更新日期：2020-11-10 00:00:00

abstract：:Corona phase molecular recognition (CoPhMoRe) uses a heteropolymer adsorbed onto and templated by a nanoparticle surface to recognize a specific target analyte. This method has not yet been extended to macromolecular analytes, including proteins. Herein we develop a variant of a CoPhMoRe screening procedure of single-...

journal_title：Nature communications

authors： Bisker G,Dong J,Park HD,Iverson NM,Ahn J,Nelson JT,Landry MP,Kruss S,Strano MS

更新日期：2016-01-08 00:00:00

abstract：:Supercooled liquids exhibit spatial heterogeneity in the dynamics of their fluctuating atomic arrangements. The length and time scales of the heterogeneous dynamics are central to the glass transition and influence nucleation and growth of crystals from the liquid. Here, we report direct experimental visualization of ...

journal_title：Nature communications

authors： Zhang P,Maldonis JJ,Liu Z,Schroers J,Voyles PM

更新日期：2018-03-19 00:00:00

abstract：:Melting of the Greenland Ice Sheet is a leading cause of land-ice mass loss and cryosphere-attributed sea level rise. Blooms of pigmented glacier ice algae lower ice albedo and accelerate surface melting in the ice sheet's southwest sector. Although glacier ice algae cause up to 13% of the surface melting in this regi...

journal_title：Nature communications

authors： McCutcheon J,Lutz S,Williamson C,Cook JM,Tedstone AJ,Vanderstraeten A,Wilson SA,Stockdale A,Bonneville S,Anesio AM,Yallop ML,McQuaid JB,Tranter M,Benning LG

更新日期：2021-01-25 00:00:00

abstract：:Inorganic perovskites such as CsPbX3 (X=Cl, Br, I) have attracted attention due to their excellent thermal stability and high photoluminescence quantum efficiency. However, the electroluminescence quantum efficiency of their light-emitting diodes was <1%. We posited that this low efficiency was a result of high leakag...

journal_title：Nature communications

authors： Zhang L,Yang X,Jiang Q,Wang P,Yin Z,Zhang X,Tan H,Yang YM,Wei M,Sutherland BR,Sargent EH,You J

更新日期：2017-06-07 00:00:00

abstract：:The recent levelling of global mean temperatures after the late 1990s, the so-called global warming hiatus or slowdown, ignited a surge of scientific interest into natural global mean surface temperature variability, observed temperature biases, and climate communication, but many questions remain about how these find...

journal_title：Nature communications

authors： Johnson NC,Xie SP,Kosaka Y,Li X

更新日期：2018-04-30 00:00:00

abstract：:Little is known about how our brains dynamically adapt for efficient functioning. Most previous work has focused on analyzing changes in co-fluctuations between a set of brain regions over several temporal segments of the data. We argue that by collapsing data in space or time, we stand to lose useful information abou...

journal_title：Nature communications

authors： Saggar M,Sporns O,Gonzalez-Castillo J,Bandettini PA,Carlsson G,Glover G,Reiss AL

更新日期：2018-04-11 00:00:00

abstract：:Stable benzotriazinyl radicals (Blatter's radicals) recently attracted considerable interest as building blocks for functional materials. The existing strategies to derivatize Blatter's radicals are limited, however, and synthetic routes are complex. Here, we report that an inexpensive, commercially available, analyti...

journal_title：Nature communications

authors： Grant JA,Lu Z,Tucker DE,Hockin BM,Yufit DS,Fox MA,Kataky R,Chechik V,O'Donoghue AC

更新日期：2017-05-15 00:00:00

abstract：:Bloch electrons lacking inversion symmetry exhibit orbital magnetic moments owing to the rotation around their center of mass; this moment induces a valley splitting in a magnetic field. For the graphene/h-BN moiré superlattice, inversion symmetry is broken by the h-BN. The superlattice potential generates a series of...

journal_title：Nature communications

authors： Moriya R,Kinoshita K,Crosse JA,Watanabe K,Taniguchi T,Masubuchi S,Moon P,Koshino M,Machida T

更新日期：2020-10-23 00:00:00

abstract：:A phase transition is often accompanied by the appearance of an order parameter and symmetry breaking. Certain magnetic materials exhibit exotic hidden-order phases, in which the order parameters are not directly accessible to conventional magnetic measurements. Thus, experimental identification and theoretical unders...

journal_title：Nature communications

authors： Shen Y,Liu C,Qin Y,Shen S,Li YD,Bewley R,Schneidewind A,Chen G,Zhao J

更新日期：2019-10-08 00:00:00