Publisher Correction: A square-root topological insulator with non-quantized indices realized with photonic Aharonov-Bohm cages.

abstract：:Atherosclerosis is characterized by the accumulation of lipids within the arterial wall. Although activation of TRPV1 cation channels by capsaicin may reduce lipid storage and the formation of atherosclerotic lesions, a clinical use for capsaicin has been limited by its chronic toxicity. Here we show that coupling of ...

journal_title：Nature communications

authors： Gao W,Sun Y,Cai M,Zhao Y,Cao W,Liu Z,Cui G,Tang B

更新日期：2018-01-15 00:00:00

abstract：:Oxygen vacancies in proximity to surfaces and heterointerfaces in oxide thin film heterostructures have major effects on properties, resulting, for example, in emergent conduction behaviour, large changes in metal-insulator transition temperatures or enhanced catalytic activity. Here we report the discovery of a means...

journal_title：Nature communications

authors： Veal BW,Kim SK,Zapol P,Iddir H,Baldo PM,Eastman JA

更新日期：2016-06-10 00:00:00

abstract：:Two voltage-gated calcium channel subtypes-CaV1.2 and CaV1.3-underlie the major L-type Ca(2+) currents in the mammalian central nervous system. Owing to their high sequence homology, the two channel subtypes share similar pharmacological properties, and at high doses classic calcium channel blockers, such as dihydropy...

journal_title：Nature communications

authors： Huang H,Ng CY,Yu D,Zhai J,Lam Y,Soong TW

更新日期：2014-07-24 00:00:00

abstract：:Myopia can cause severe visual impairment. Here, we report a two-stage genome-wide association study for three myopia-related traits in 9,804 Japanese individuals, which was extended with trans-ethnic replication in 2,674 Chinese and 2,690 Caucasian individuals. We identify WNT7B as a novel susceptibility gene for axi...

journal_title：Nature communications

authors： Miyake M,Yamashiro K,Tabara Y,Suda K,Morooka S,Nakanishi H,Khor CC,Chen P,Qiao F,Nakata I,Akagi-Kurashige Y,Gotoh N,Tsujikawa A,Meguro A,Kusuhara S,Polasek O,Hayward C,Wright AF,Campbell H,Richardson AJ,Schache M

更新日期：2015-03-31 00:00:00

abstract：:Homologous recombination-mediated gene targeting has greatly contributed to genetic analysis in a wide range of species, but is highly inefficient in human cells because of overwhelmingly frequent random integration events, whose molecular mechanism remains elusive. Here we show that DNA polymerase θ, despite its mino...

journal_title：Nature communications

authors： Saito S,Maeda R,Adachi N

更新日期：2017-07-11 00:00:00

abstract：:Excessive nitrogen runoff leads to degraded water quality, harming human and ecosystem health. We examine the impact of changes in land use and land management for six combinations of socioeconomic pathways and climate outcomes, and find that societal choices will substantially impact riverine total nitrogen loading (...

journal_title：Nature communications

authors： Sinha E,Michalak AM,Calvin KV,Lawrence PJ

更新日期：2019-02-26 00:00:00

abstract：:FeV(O)(OH) species have long been proposed to play a key role in a wide range of biomimetic and enzymatic oxidations, including as intermediates in arene dihydroxylation catalyzed by Rieske oxygenases. However, the inability to accumulate these intermediates in solution has thus far prevented their spectroscopic and c...

journal_title：Nature communications

authors： Borrell M,Andris E,Navrátil R,Roithová J,Costas M

更新日期：2019-02-22 00:00:00

abstract：:TP53 mutations are the most frequent genetic alterations in breast cancer and are associated with more aggressive disease and worse overall survival. We have created two conditional mutant Trp53 alleles in the mouse that allow expression of Trp53R172H or Trp53R245W missense mutations in single cells surrounded by a no...

journal_title：Nature communications

authors： Zhang Y,Xiong S,Liu B,Pant V,Celii F,Chau G,Elizondo-Fraire AC,Yang P,You MJ,El-Naggar AK,Navin NE,Lozano G

更新日期：2018-09-27 00:00:00

abstract：:Exfoliated two-dimensional (2D) sheets can readily stack to form flexible, free-standing films with lamellar microstructure. The interlayer spaces in such lamellar films form a percolated network of molecularly sized, 2D nanochannels that could be used to regulate molecular transport. Here we report self-assembled cla...

journal_title：Nature communications

authors： Shao JJ,Raidongia K,Koltonow AR,Huang J

更新日期：2015-07-13 00:00:00

abstract：:Graphite dual-ion batteries represent a potential battery concept for large-scale stationary storage of electricity, especially when constructed free of lithium and other chemical elements with limited natural reserves. Owing to their non-rocking-chair operation mechanism, however, the practical deployment of graphite...

journal_title：Nature communications

authors： Kravchyk KV,Bhauriyal P,Piveteau L,Guntlin CP,Pathak B,Kovalenko MV

更新日期：2018-10-26 00:00:00

abstract：:CD24 is overexpressed in nearly 70% human cancers, whereas TP53 is the most frequently mutated tumour-suppressor gene that functions in a context-dependent manner. Here we show that both targeted mutation and short hairpin RNA (shRNA) silencing of CD24 retard the growth, progression and metastasis of prostate cancer. ...

journal_title：Nature communications

authors： Wang L,Liu R,Ye P,Wong C,Chen GY,Zhou P,Sakabe K,Zheng X,Wu W,Zhang P,Jiang T,Bassetti MF,Jube S,Sun Y,Zhang Y,Zheng P,Liu Y

更新日期：2015-01-20 00:00:00

abstract：:Covalent functionalization tailors carbon nanotubes for a wide range of applications in varying environments. Its strength and stability of attachment come at the price of degrading the carbon nanotubes sp2 network and destroying the tubes electronic and optoelectronic features. Here we present a non-destructive, cova...

journal_title：Nature communications

authors： Setaro A,Adeli M,Glaeske M,Przyrembel D,Bisswanger T,Gordeev G,Maschietto F,Faghani A,Paulus B,Weinelt M,Arenal R,Haag R,Reich S

更新日期：2017-01-30 00:00:00

abstract：:Photocatalysis has not found widespread industrial adoption, in spite of decades of active research, because the challenges associated with catalyst illumination and turnover outweigh the touted advantages of replacing heat with light. A demonstration that light can control product selectivity in complex chemical reac...

journal_title：Nature communications

authors： Zhang X,Li X,Zhang D,Su NQ,Yang W,Everitt HO,Liu J

更新日期：2017-02-23 00:00:00

abstract：:Transport of nanoscale energy in the form of excitons is at the core of photosynthesis and the operation of a wide range of nanostructured optoelectronic devices such as solar cells, light-emitting diodes and excitonic transistors. Of particular importance is the relationship between exciton transport and nanoscale di...

journal_title：Nature communications

authors： Akselrod GM,Deotare PB,Thompson NJ,Lee J,Tisdale WA,Baldo MA,Menon VM,Bulović V

更新日期：2014-04-16 00:00:00

abstract：:Large-scale genetic and genomic data are increasingly available and the major bottleneck in their analysis is a lack of sufficiently scalable computational tools. To address this problem in the context of complex traits analysis, we present DISSECT. DISSECT is a new and freely available software that is able to exploi...

journal_title：Nature communications

authors： Canela-Xandri O,Law A,Gray A,Woolliams JA,Tenesa A

更新日期：2015-12-11 00:00:00

abstract：:Understanding and extracting the full functions of single-molecule characteristics are key factors in the development of future device technologies, as well as in basic research on molecular electronics. Here we report a new methodology for realizing a three-dimensional (3D) dynamic probe of single-molecule conductanc...

journal_title：Nature communications

authors： Nakamura M,Yoshida S,Katayama T,Taninaka A,Mera Y,Okada S,Takeuchi O,Shigekawa H

更新日期：2015-10-06 00:00:00

abstract：:Weyl points, as monopoles of Berry curvature in momentum space, have captured much attention recently in various branches of physics. Realizing topological materials that exhibit such nodal points is challenging and indeed, Weyl points have been found experimentally in transition metal arsenide and phosphide and gyroi...

journal_title：Nature communications

authors： Chen WJ,Xiao M,Chan CT

更新日期：2016-10-05 00:00:00

abstract：:The interface between LaAlO(3) and SrTiO(3) possesses a range of intriguing properties, notably a proposed connection between the surface state of the LaAlO(3) and the conductivity buried in the SrTiO(3). Here we study the effect of the surface adsorption of a variety of common laboratory solvents on the conductivity ...

journal_title：Nature communications

authors： Xie Y,Hikita Y,Bell C,Hwang HY

更新日期：2011-10-11 00:00:00

abstract：:Clostridium difficile is the leading cause of pseudomembranous colitis in hospitalized patients. C. difficile enterotoxins TcdA and TcdB promote this inflammatory condition via a cytotoxic response on intestinal epithelial cells (IECs), but the underlying mechanisms are incompletely understood. Additionally, TcdA and ...

journal_title：Nature communications

authors： Saavedra PHV,Huang L,Ghazavi F,Kourula S,Vanden Berghe T,Takahashi N,Vandenabeele P,Lamkanfi M

更新日期：2018-11-19 00:00:00

abstract：:Many physical phenomena can be understood by single-particle physics; that is, treating particles as non-interacting entities. When this fails, many-body interactions lead to spontaneous symmetry breaking and phenomena such as fundamental particles' mass generation, superconductivity and magnetism. Competition between...

journal_title：Nature communications

authors： Lee Y,Tran D,Myhro K,Velasco J,Gillgren N,Lau CN,Barlas Y,Poumirol JM,Smirnov D,Guinea F

更新日期：2014-12-12 00:00:00

abstract：:Synaptic vesicle (SV) exocytosis is mediated by SNARE proteins. Reconstituted SNAREs are constitutively active, so a major focus has been to identify fusion clamps that regulate their activity in synapses: the primary candidates are synaptotagmin (syt) 1 and complexin I/II. Syt1 is a Ca2+ sensor for SV release that bi...

journal_title：Nature communications

authors： Courtney NA,Bao H,Briguglio JS,Chapman ER

更新日期：2019-09-09 00:00:00

abstract：:Intramolecular photostabilization via triple-state quenching was recently revived as a tool to impart synthetic organic fluorophores with 'self-healing' properties. To date, utilization of such fluorophore derivatives is rare due to their elaborate multi-step synthesis. Here we present a general strategy to covalently...

journal_title：Nature communications

authors： van der Velde JH,Oelerich J,Huang J,Smit JH,Aminian Jazi A,Galiani S,Kolmakov K,Guoridis G,Eggeling C,Herrmann A,Roelfes G,Cordes T

更新日期：2016-01-11 00:00:00

abstract：:Staphylococcal pathogens adhere to their human targets with exceptional resilience to mechanical stress, some propagating force to the bacterium via small, Ig-like folds called B domains. We examine the mechanical stability of these folds using atomic force microscopy-based single-molecule force spectroscopy. The forc...

journal_title：Nature communications

authors： Milles LF,Unterauer EM,Nicolaus T,Gaub HE

更新日期：2018-11-12 00:00:00

abstract：:Incorporating oxophilic metals into noble metal-based catalysts represents an emerging strategy to improve the catalytic performance of electrocatalysts in fuel cells. However, effects of the distance between the noble metal and oxophilic metal active sites on the catalytic performance have rarely been investigated. H...

journal_title：Nature communications

authors： Chen L,Lu L,Zhu H,Chen Y,Huang Y,Li Y,Wang L

更新日期：2017-01-10 00:00:00

abstract：:Maintenance of genome integrity via repair of DNA damage is a key biological process required to suppress diseases, including Fanconi anemia (FA). We generated loss-of-function human haploid cells for FA complementation group C (FANCC), a gene encoding a component of the FA core complex, and used genome-wide CRISPR li...

journal_title：Nature communications

authors： Moder M,Velimezi G,Owusu M,Mazouzi A,Wiedner M,Ferreira da Silva J,Robinson-Garcia L,Schischlik F,Slavkovsky R,Kralovics R,Schuster M,Bock C,Ideker T,Jackson SP,Menche J,Loizou JI

更新日期：2017-11-01 00:00:00

abstract：:Soil surface temperature, an important driver of terrestrial biogeochemical processes, depends strongly on soil albedo, which can be significantly modified by factors such as plant cover. In sparsely vegetated lands, the soil surface can be colonized by photosynthetic microbes that build biocrust communities. Here we ...

journal_title：Nature communications

authors： Couradeau E,Karaoz U,Lim HC,Nunes da Rocha U,Northen T,Brodie E,Garcia-Pichel F

更新日期：2016-01-20 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Nature communications

authors： Masid M,Ataman M,Hatzimanikatis V

更新日期：2020-07-23 00:00:00

abstract：:Epilepsy is a common brain disorder throughout history. Epilepsy-related ligand-receptor complex, LGI1-ADAM22, regulates synaptic transmission and has emerged as a determinant of brain excitability, as their mutations and acquired LGI1 autoantibodies cause epileptic disorders in human. Here, we report the crystal stru...

journal_title：Nature communications

authors： Yamagata A,Miyazaki Y,Yokoi N,Shigematsu H,Sato Y,Goto-Ito S,Maeda A,Goto T,Sanbo M,Hirabayashi M,Shirouzu M,Fukata Y,Fukata M,Fukai S

更新日期：2018-04-18 00:00:00

abstract：:Fluorescence imaging in the second near-infrared window (NIR-II) allows visualization of deep anatomical features with an unprecedented degree of clarity. NIR-II fluorophores draw from a broad spectrum of materials spanning semiconducting nanomaterials to organic molecular dyes, yet unfortunately all water-soluble org...

journal_title：Nature communications

authors： Antaris AL,Chen H,Diao S,Ma Z,Zhang Z,Zhu S,Wang J,Lozano AX,Fan Q,Chew L,Zhu M,Cheng K,Hong X,Dai H,Cheng Z

更新日期：2017-05-19 00:00:00

abstract：:Autophagy is the main homeostatic pathway guiding cytosolic materials for degradation by the lysosome. Maturation of autophagosomes requires their transport towards the perinuclear region of the cell, with key factors underlying both processes still poorly understood. Here we show that transport and positioning of lat...

journal_title：Nature communications

authors： Wijdeven RH,Janssen H,Nahidiazar L,Janssen L,Jalink K,Berlin I,Neefjes J

更新日期：2016-06-10 00:00:00