Preserving π-conjugation in covalently functionalized carbon nanotubes for optoelectronic applications.

abstract：:Two-dimensional materials provide extraordinary opportunities for exploring phenomena arising in atomically thin crystals. Beginning with the first isolation of graphene, mechanical exfoliation has been a key to provide high-quality two-dimensional materials, but despite improvements it is still limited in yield, late...

journal_title：Nature communications

authors： Huang Y,Pan YH,Yang R,Bao LH,Meng L,Luo HL,Cai YQ,Liu GD,Zhao WJ,Zhou Z,Wu LM,Zhu ZL,Huang M,Liu LW,Liu L,Cheng P,Wu KH,Tian SB,Gu CZ,Shi YG,Guo YF,Cheng ZG,Hu JP,Zhao L,Yang GH,Sutter E,Sutter P,Wan

更新日期：2020-05-15 00:00:00

abstract：:The complex transport processes contributing to sintering are not yet fully understood, partially because in-situ observations of sintering in three dimensions (3D) are very difficult. Here we report a novel experiment in which monocrystalline copper spheres are first marked with microscopic boreholes drilled using a ...

journal_title：Nature communications

authors： Grupp R,Nöthe M,Kieback B,Banhart J

更新日期：2011-01-01 00:00:00

abstract：:Cell-to-cell variability plays a critical role in cellular responses and decision-making in a population, and transcriptional bursting has been broadly studied by experimental and theoretical approaches as the potential source of cell-to-cell variability. Although molecular mechanisms of transcriptional bursting have ...

journal_title：Nature communications

authors： Fujita K,Iwaki M,Yanagida T

更新日期：2016-12-07 00:00:00

abstract：:Using asymmetric catalysis to simultaneously form carbon-carbon bonds and generate single isomer products is strategically important. Suzuki-Miyaura cross-coupling is widely used in the academic and industrial sectors to synthesize drugs, agrochemicals and biologically active and advanced materials. However, widely ap...

journal_title：Nature communications

authors： Schäfer P,Palacin T,Sidera M,Fletcher SP

更新日期：2017-06-13 00:00:00

abstract：:The TORC1 complex controls cell growth upon integrating nutritional signals including amino-acid availability. TORC1 notably adapts the plasma membrane protein content by regulating arrestin-mediated endocytosis of amino-acid transporters. Here we demonstrate that TORC1 further fine tunes the inherent activity of the ...

journal_title：Nature communications

authors： Boeckstaens M,Llinares E,Van Vooren P,Marini AM

更新日期：2014-01-01 00:00:00

abstract：:Bacterial Type III Secretion Systems deliver effectors into host cells to manipulate cellular processes to the advantage of the pathogen. Many host targets of these effectors are found on membranes. Therefore, to identify their targets, effectors often use specialized membrane-localization domains to localize to appro...

journal_title：Nature communications

authors： Salomon D,Guo Y,Kinch LN,Grishin NV,Gardner KH,Orth K

更新日期：2013-01-01 00:00:00

abstract：:Taxanes are the only chemotherapies used to treat patients with metastatic castration-resistant prostate cancer (CRPC). Despite the initial efficacy of taxanes in treating CRPC, all patients ultimately fail due to the development of drug resistance. In this study, we show that ERG overexpression in in vitro and in viv...

journal_title：Nature communications

authors： Galletti G,Matov A,Beltran H,Fontugne J,Miguel Mosquera J,Cheung C,MacDonald TY,Sung M,O'Toole S,Kench JG,Suk Chae S,Kimovski D,Tagawa ST,Nanus DM,Rubin MA,Horvath LG,Giannakakou P,Rickman DS

更新日期：2014-11-25 00:00:00

abstract：:The importance of metabolism in macrophage function has been reported, but the in vivo relevance of the in vitro observations is still unclear. Here we show that macrophage metabolites are defined in a specific tissue context, and these metabolites are crucially linked to tissue-resident macrophage functions. We find ...

journal_title：Nature communications

authors： Davies LC,Rice CM,Palmieri EM,Taylor PR,Kuhns DB,McVicar DW

更新日期：2017-12-12 00:00:00

abstract：:Writing artificial logic and dynamic function into complex cellular background to achieve desired phenotypes or improved outputs calls for the development of new genetic tools as well as their innovative use. In this study, we present a sensor-regulator and RNAi-based bifunctional dynamic control network that can prov...

journal_title：Nature communications

authors： Yang Y,Lin Y,Wang J,Wu Y,Zhang R,Cheng M,Shen X,Wang J,Chen Z,Li C,Yuan Q,Yan Y

更新日期：2018-08-02 00:00:00

abstract：:Metals and polymers are dissimilar materials in terms of their physicochemical properties, but complementary in terms of functionality. As a result, metal-organic structures can introduce a wealth of novel applications in small-scale robotics. However, current fabrication techniques are unable to process three-dimensi...

journal_title：Nature communications

authors： Alcântara CCJ,Landers FC,Kim S,De Marco C,Ahmed D,Nelson BJ,Pané S

更新日期：2020-11-24 00:00:00

abstract：:Pancreatic cancer is the fourth leading cause of cancer-related deaths in Japan. To identify risk loci, we perform a meta-analysis of three genome-wide association studies comprising 2,039 pancreatic cancer patients and 32,592 controls in the Japanese population. Here, we identify 3 (13q12.2, 13q22.1, and 16p12.3) gen...

journal_title：Nature communications

authors： Lin Y,Nakatochi M,Hosono Y,Ito H,Kamatani Y,Inoko A,Sakamoto H,Kinoshita F,Kobayashi Y,Ishii H,Ozaka M,Sasaki T,Matsuyama M,Sasahira N,Morimoto M,Kobayashi S,Fukushima T,Ueno M,Ohkawa S,Egawa N,Kuruma S,Mori M,

更新日期：2020-06-24 00:00:00

abstract：:Hundreds of clinical studies have demonstrated associations between the human microbiome and disease, yet fundamental questions remain on how we can generalize this knowledge. Results from individual studies can be inconsistent, and comparing published data is further complicated by a lack of standard processing and a...

journal_title：Nature communications

authors： Duvallet C,Gibbons SM,Gurry T,Irizarry RA,Alm EJ

更新日期：2017-12-05 00:00:00

abstract：:Molecularly defined subclassification is associated with phenotypic malignancy of glioblastoma (GBM). However, current understanding of the molecular basis of subclass conversion that is often involved in GBM recurrence remain rudimentary at best. Here we report that canonical Wnt signalling that is active in proneura...

journal_title：Nature communications

authors： Huang T,Alvarez AA,Pangeni RP,Horbinski CM,Lu S,Kim SH,James CD,J Raizer J,A Kessler J,Brenann CW,Sulman EP,Finocchiaro G,Tan M,Nishikawa R,Lu X,Nakano I,Hu B,Cheng SY

更新日期：2016-10-04 00:00:00

abstract：:Six CO2 fixation pathways are known to operate in photoautotrophic and chemoautotrophic microorganisms. Here, we describe chemolithoautotrophic growth of the sulphate-reducing bacterium Desulfovibrio desulfuricans (strain G11) with hydrogen and sulphate as energy substrates. Genomic, transcriptomic, proteomic and meta...

journal_title：Nature communications

authors： Sánchez-Andrea I,Guedes IA,Hornung B,Boeren S,Lawson CE,Sousa DZ,Bar-Even A,Claassens NJ,Stams AJM

更新日期：2020-10-09 00:00:00

abstract：:Replicating biological patterns is promising for designing materials with multifaceted properties. Twisted cholesteric liquid crystal patterns are found in the iridescent tessellated cuticles of many insects and a few fruits. Their accurate replication is extremely difficult since discontinuous patterns and colors mus...

journal_title：Nature communications

authors： Scarangella A,Soldan V,Mitov M

更新日期：2020-08-14 00:00:00

abstract：:A variant at amino acid 47 in human TP53 exists predominantly in individuals of African descent. P47S human and mouse cells show increased cancer risk due to defective ferroptosis. Here, we show that this ferroptotic defect causes iron accumulation in P47S macrophages. This high iron content alters macrophage cytokine...

journal_title：Nature communications

authors： Singh KS,Leu JI,Barnoud T,Vonteddu P,Gnanapradeepan K,Lin C,Liu Q,Barton JC,Kossenkov AV,George DL,Murphy ME,Dotiwala F

更新日期：2020-01-24 00:00:00

abstract：:Cancer persister cells tolerate anticancer drugs and serve as the founders of acquired resistance and cancer relapse. Here we show that a subpopulation of BRAFV600 mutant melanoma cells that tolerates exposure to BRAF and MEK inhibitors undergoes a reversible remodelling of mRNA translation that evolves in parallel wi...

journal_title：Nature communications

authors： Shen S,Faouzi S,Bastide A,Martineau S,Malka-Mahieu H,Fu Y,Sun X,Mateus C,Routier E,Roy S,Desaubry L,André F,Eggermont A,David A,Scoazec JY,Vagner S,Robert C

更新日期：2019-12-16 00:00:00

abstract：:Solid-state quantum acoustodynamic (QAD) systems provide a compact platform for quantum information storage and processing by coupling acoustic phonon sources with superconducting or spin qubits. The multi-mode composite high-overtone bulk acoustic wave resonator (HBAR) is a popular phonon source well suited for QAD. ...

journal_title：Nature communications

authors： Gokhale VJ,Downey BP,Katzer DS,Nepal N,Lang AC,Stroud RM,Meyer DJ

更新日期：2020-05-08 00:00:00

abstract：:The coupling of compartmentalisation with molecular replication is thought to be crucial for the emergence of the first evolvable chemical systems. Minimal artificial replicators have been designed based on molecular recognition, inspired by the template copying of DNA, but none yet have been coupled to compartmentali...

journal_title：Nature communications

authors： Taylor JW,Eghtesadi SA,Points LJ,Liu T,Cronin L

更新日期：2017-08-10 00:00:00

abstract：:Generous behaviour is known to increase happiness, which could thereby motivate generosity. In this study, we use functional magnetic resonance imaging and a public pledge for future generosity to investigate the brain mechanisms that link generous behaviour with increases in happiness. Participants promised to spend ...

journal_title：Nature communications

authors： Park SQ,Kahnt T,Dogan A,Strang S,Fehr E,Tobler PN

更新日期：2017-07-11 00:00:00

abstract：:Osmoregulation is important for plant growth, development and response to environmental changes. SNF1-related protein kinase 2s (SnRK2s) are quickly activated by osmotic stress and are central components in osmotic stress and abscisic acid (ABA) signaling pathways; however, the upstream components required for SnRK2 a...

journal_title：Nature communications

authors： Lin Z,Li Y,Zhang Z,Liu X,Hsu CC,Du Y,Sang T,Zhu C,Wang Y,Satheesh V,Pratibha P,Zhao Y,Song CP,Tao WA,Zhu JK,Wang P

更新日期：2020-01-30 00:00:00

abstract：:The developing CA3 hippocampus is comprised by highly connected hub neurons that are particularly effective in achieving network synchronization. Functional hub neurons were shown to be exclusively GABAergic, suggesting that the contribution of glutamatergic neurons to physiological synchronization processes at early ...

journal_title：Nature communications

authors： Marissal T,Bonifazi P,Picardo MA,Nardou R,Petit LF,Baude A,Fishell GJ,Ben-Ari Y,Cossart R

更新日期：2012-01-01 00:00:00

abstract：:The three-dimensional architecture of the genome affects genomic functions. Multiple genome architectures at different length scales, including chromatin loops, domains, compartments, and lamina- and nucleolus-associated regions, have been discovered. However, how these structures are arranged in the same cell and how...

journal_title：Nature communications

authors： Liu M,Lu Y,Yang B,Chen Y,Radda JSD,Hu M,Katz SG,Wang S

更新日期：2020-06-09 00:00:00

abstract：:Mitochondria and peroxisomes proliferate by division. During division, a part of their membrane is pinched off by constriction of the ring-shaped mitochondrial division (MD) and peroxisome-dividing (POD) machinery. This constriction is mediated by a dynamin-like GTPase Dnm1 that requires a large amount of GTP as an en...

journal_title：Nature communications

authors： Imoto Y,Abe Y,Honsho M,Okumoto K,Ohnuma M,Kuroiwa H,Kuroiwa T,Fujiki Y

更新日期：2018-11-06 00:00:00

abstract：:Nervous systems exhibit myriad cell types, but understanding how this diversity arises is hampered by the difficulty to visualize and genetically-probe specific lineages, especially at early developmental stages prior to expression of unique molecular markers. Here, we use a genetic immortalization method to analyze t...

journal_title：Nature communications

authors： Chai PC,Cruchet S,Wigger L,Benton R

更新日期：2019-02-07 00:00:00

abstract：:Saccharomyces cerevisiae is a Crabtree-positive eukaryal model organism. It is believed that the Crabtree effect has evolved as a competition mechanism by allowing for rapid growth and production of ethanol at aerobic glucose excess conditions. This inherent property of yeast metabolism and the multiple mechanisms und...

journal_title：Nature communications

authors： Dai Z,Huang M,Chen Y,Siewers V,Nielsen J

更新日期：2018-08-03 00:00:00

abstract：:The search for two-dimensional quantum spin liquids, exotic magnetic states remaining disordered down to zero temperature, has been a great challenge in frustrated magnetism over the last few decades. Recently, evidence for fractionalized excitations, called spinons, emerging from these states has been observed in kag...

journal_title：Nature communications

authors： Lhotel E,Petit S,Ciomaga Hatnean M,Ollivier J,Mutka H,Ressouche E,Lees MR,Balakrishnan G

更新日期：2018-09-17 00:00:00

abstract：:The gravitational collapse of eruption columns generates ground-hugging pyroclastic density currents (PDCs) with highly variable temperatures, high enough to be a threat for communities surrounding volcanoes. The reasons for such great temperature variability are debated in terms of eruptive versus transport and empla...

journal_title：Nature communications

authors： Trolese M,Cerminara M,Esposti Ongaro T,Giordano G

更新日期：2019-06-06 00:00:00

abstract：:The ability to simultaneously image multiple biomolecules in biologically relevant three-dimensional (3D) cell culture environments would contribute greatly to the understanding of complex cellular mechanisms and cell-material interactions. Here, we present a computational framework for label-free quantitative volumet...

journal_title：Nature communications

authors： Kallepitis C,Bergholt MS,Mazo MM,Leonardo V,Skaalure SC,Maynard SA,Stevens MM

更新日期：2017-03-22 00:00:00

abstract：:Autophagy can degrade cargos with the help of selective autophagy receptors such as p62/SQSTM1, which facilitates the degradation of ubiquitinated cargo. While the process of autophagy has been linked to aging, the impact of selective autophagy in lifespan regulation remains unclear. We have recently shown in Caenorha...

journal_title：Nature communications

authors： Kumsta C,Chang JT,Lee R,Tan EP,Yang Y,Loureiro R,Choy EH,Lim SHY,Saez I,Springhorn A,Hoppe T,Vilchez D,Hansen M

更新日期：2019-12-11 00:00:00