Onsite GTP fuelling via DYNAMO1 drives division of mitochondria and peroxisomes.

abstract：:How are memories transferred from short-term to long-term storage? Systems-level memory consolidation is thought to be dependent on the coordinated interplay of cortical slow waves, thalamo-cortical sleep spindles and hippocampal ripple oscillations. However, it is currently unclear how the selective interaction of th...

journal_title：Nature communications

authors： Helfrich RF,Lendner JD,Mander BA,Guillen H,Paff M,Mnatsakanyan L,Vadera S,Walker MP,Lin JJ,Knight RT

更新日期：2019-08-08 00:00:00

abstract：:Removal of internal transcribed spacer 2 (ITS2) from pre-ribosomal RNA is essential to make functional ribosomes. This complicated processing reaction begins with a single endonucleolytic cleavage followed by exonucleolytic trimming at both new cleavage sites to generate mature 5.8S and 25S rRNA. We reconstituted the ...

journal_title：Nature communications

authors： Fromm L,Falk S,Flemming D,Schuller JM,Thoms M,Conti E,Hurt E

更新日期：2017-11-27 00:00:00

abstract：:How genomic and transcriptomic alterations affect the functional proteome in lung cancer is not fully understood. Here, we integrate DNA copy number, somatic mutations, RNA-sequencing, and expression proteomics in a cohort of 108 squamous cell lung cancer (SCC) patients. We identify three proteomic subtypes, two of wh...

journal_title：Nature communications

authors： Stewart PA,Welsh EA,Slebos RJC,Fang B,Izumi V,Chambers M,Zhang G,Cen L,Pettersson F,Zhang Y,Chen Z,Cheng CH,Thapa R,Thompson Z,Fellows KM,Francis JM,Saller JJ,Mesa T,Zhang C,Yoder S,DeNicola GM,Beg AA,Boyle TA

更新日期：2019-08-08 00:00:00

abstract：:Respiration by soil bacteria and fungi is one of the largest fluxes of carbon (C) from the land surface. Although this flux is a direct product of microbial metabolism, controls over metabolism and their responses to global change are a major uncertainty in the global C cycle. Here, we explore an in silico approach to...

journal_title：Nature communications

authors： Saifuddin M,Bhatnagar JM,Segrè D,Finzi AC

更新日期：2019-08-08 00:00:00

abstract：:Natural products have traditionally been rich sources for drug discovery. In order to clear the road toward the discovery of unknown natural products, biologists need dereplication strategies that identify known ones. Here we report DEREPLICATOR+, an algorithm that improves on the previous approaches for identifying p...

journal_title：Nature communications

authors： Mohimani H,Gurevich A,Shlemov A,Mikheenko A,Korobeynikov A,Cao L,Shcherbin E,Nothias LF,Dorrestein PC,Pevzner PA

更新日期：2018-10-02 00:00:00

abstract：:The Amazon river basin receives ~2000 mm of precipitation annually and contributes ~17% of global river freshwater input to the oceans; its hydroclimatic variations can exert profound impacts on the marine ecosystem in the Amazon plume region (APR) and have potential far-reaching influences on hydroclimate over the tr...

journal_title：Nature communications

authors： Liang YC,Lo MH,Lan CW,Seo H,Ummenhofer CC,Yeager S,Wu RJ,Steffen JD

更新日期：2020-09-01 00:00:00

abstract：:Transposable elements constitute a substantial portion of eukaryotic genomes and contribute to genomic variation, function, and evolution. Miniature inverted-repeat transposable elements (MITEs), as DNA transposons, are widely distributed in plant and animal genomes. Previous studies have suggested that retrotransposo...

journal_title：Nature communications

authors： Shen J,Liu J,Xie K,Xing F,Xiong F,Xiao J,Li X,Xiong L

更新日期：2017-03-03 00:00:00

abstract：:Variation in body iron is associated with or causes diseases, including anaemia and iron overload. Here, we analyse genetic association data on biochemical markers of iron status from 11 European-population studies, with replication in eight additional cohorts (total up to 48,972 subjects). We find 11 genome-wide-sign...

journal_title：Nature communications

authors： Benyamin B,Esko T,Ried JS,Radhakrishnan A,Vermeulen SH,Traglia M,Gögele M,Anderson D,Broer L,Podmore C,Luan J,Kutalik Z,Sanna S,van der Meer P,Tanaka T,Wang F,Westra HJ,Franke L,Mihailov E,Milani L,Hälldin J,Win

更新日期：2014-10-29 00:00:00

abstract：:Pools of carbon dioxide are found in natural geological accumulations and in engineered storage in saline aquifers. It has been thought that once this CO2 dissolves in the formation water, making it denser, convection streams will transport it efficiently to depth, but this may not be so. Here, we assess theoretically...

journal_title：Nature communications

authors： Cardoso SS,Andres JT

更新日期：2014-12-11 00:00:00

abstract：:One of the primary efforts in influenza vaccine strain recommendation is to monitor through gene sequencing the viral surface protein haemagglutinin (HA) variants that lead to viral antigenic changes. Here we have developed a computational method, denoted as PREDAC, to predict antigenic clusters of influenza A (H3N2) ...

journal_title：Nature communications

authors： Du X,Dong L,Lan Y,Peng Y,Wu A,Zhang Y,Huang W,Wang D,Wang M,Guo Y,Shu Y,Jiang T

更新日期：2012-02-28 00:00:00

abstract：:Within all physical disciplines, it is accepted that wave transport is predetermined by the existence of disorder. In this vein, it is known that ballistic transport is possible only when a structure is ordered, and that disorder is crucial for diffusion or (Anderson-)localization to occur. As this commonly accepted p...

journal_title：Nature communications

authors： Eichelkraut T,Heilmann R,Weimann S,Stützer S,Dreisow F,Christodoulides DN,Nolte S,Szameit A

更新日期：2013-01-01 00:00:00

abstract：:The process of crystallization is difficult to observe for transported, out-of-equilibrium systems, as the continuous energy injection increases activity and competes with ordering. In emerging fields such as microfluidics and active matter, the formation of long-range order is often frustrated by the presence of hydr...

journal_title：Nature communications

authors： Massana-Cid H,Meng F,Matsunaga D,Golestanian R,Tierno P

更新日期：2019-06-04 00:00:00

abstract：:The concept of spin-torque-driven high-frequency magnetization dynamics, allows the potential construction of complex networks of non-linear dynamical nanoscale systems, combining the field of spintronics and the study of non-linear systems. In the few previous demonstrations of synchronization of several spin-torque ...

journal_title：Nature communications

authors： Lebrun R,Tsunegi S,Bortolotti P,Kubota H,Jenkins AS,Romera M,Yakushiji K,Fukushima A,Grollier J,Yuasa S,Cros V

更新日期：2017-06-12 00:00:00

abstract：:Obesity is a pandemic disease associated with many metabolic alterations and involves several organs and systems. The endocannabinoid system (ECS) appears to be a key regulator of energy homeostasis and metabolism. Here we show that specific deletion of the ECS synthesizing enzyme, NAPE-PLD, in adipocytes induces obes...

journal_title：Nature communications

authors： Geurts L,Everard A,Van Hul M,Essaghir A,Duparc T,Matamoros S,Plovier H,Castel J,Denis RG,Bergiers M,Druart C,Alhouayek M,Delzenne NM,Muccioli GG,Demoulin JB,Luquet S,Cani PD

更新日期：2015-03-11 00:00:00

abstract：:Liquid sensors composed of ionic liquids are rising as alternatives to solid semiconductors for flexible and self-healing electronics. However, the fluidic nature may give rise to leakage problems in cases of accidental damages. Here, we proposed a liquid sensor based on a binary ionic liquid system, in which a flowin...

journal_title：Nature communications

authors： Gao N,He Y,Tao X,Xu XQ,Wu X,Wang Y

更新日期：2019-02-01 00:00:00

abstract：:The space charge layer (SCL) is generally considered one of the origins of the sluggish interfacial lithium-ion transport in all-solid-state lithium-ion batteries (ASSLIBs). However, in-situ visualization of the SCL effect on the interfacial lithium-ion transport in sulfide-based ASSLIBs is still a great challenge. He...

journal_title：Nature communications

authors： Wang L,Xie R,Chen B,Yu X,Ma J,Li C,Hu Z,Sun X,Xu C,Dong S,Chan TS,Luo J,Cui G,Chen L

更新日期：2020-11-18 00:00:00

abstract：:Protein post-translational modifications (PTMs) play important roles in the control of various biological processes including protein-protein interactions, epigenetics and cell cycle regulation. Mass spectrometry-based proteomics approaches enable comprehensive identification and quantitation of numerous types of PTMs...

journal_title：Nature communications

authors： Abshiru N,Caron-Lizotte O,Rajan RE,Jamai A,Pomies C,Verreault A,Thibault P

更新日期：2015-10-15 00:00:00

abstract：:Generation and recombination of electrons and holes in organic solar cells occurs via charge transfer states located at the donor/acceptor interface. The energy of these charge transfer states is a crucial factor for the attainable open-circuit voltage and its correct determination is thus of utmost importance for a d...

journal_title：Nature communications

authors： List M,Sarkar T,Perkhun P,Ackermann J,Luo C,Würfel U

更新日期：2018-09-07 00:00:00

abstract：:Ferroelectric materials exhibit a phase transition to a paraelectric state driven by temperature - called the Curie transition. In conventional ferroelectrics, the Curie transition is caused by a change in crystal symmetry, while the material itself remains a continuous three-dimensional solid crystal. However, ferroe...

journal_title：Nature communications

authors： Hafner J,Benaglia S,Richheimer F,Teuschel M,Maier FJ,Werner A,Wood S,Platz D,Schneider M,Hradil K,Castro FA,Garcia R,Schmid U

更新日期：2021-01-08 00:00:00

abstract：:Ultrafast photoinduced electron transfer preceding energy equilibration still poses many experimental and conceptual challenges to the optimization of photoconversion since an atomic-scale description has so far been beyond reach. Here we combine femtosecond transient optical absorption spectroscopy with ultrafast X-r...

journal_title：Nature communications

authors： Canton SE,Kjær KS,Vankó G,van Driel TB,Adachi S,Bordage A,Bressler C,Chabera P,Christensen M,Dohn AO,Galler A,Gawelda W,Gosztola D,Haldrup K,Harlang T,Liu Y,Møller KB,Németh Z,Nozawa S,Pápai M,Sato T,Sato T,Su

更新日期：2015-03-02 00:00:00

abstract：:High-gamma signals mirror the tuning and temporal profiles of neurons near a recording electrode in sensory and motor areas. These frequencies appear to aggregate local neuronal activity, but it is unclear how this relationship affects information encoding in high-gamma activity (HGA) in cortical areas where neurons a...

journal_title：Nature communications

authors： Rich EL,Wallis JD

更新日期：2017-10-26 00:00:00

abstract：:Transposons are known to participate in tissue aging, but their effects on aged stem cells remain unclear. Here, we report that in the Drosophila ovarian germline stem cell (GSC) niche, aging-related reductions in expression of Piwi (a transposon silencer) derepress retrotransposons and cause GSC loss. Suppression of ...

journal_title：Nature communications

authors： Lin KY,Wang WD,Lin CH,Rastegari E,Su YH,Chang YT,Liao YF,Chang YC,Pi H,Yu BY,Chen SH,Lin CY,Lu MY,Su TY,Tzou FY,Chan CC,Hsu HJ

更新日期：2020-06-19 00:00:00

abstract：:An evolutionary account of human language as a neurobiological system must distinguish between human-unique neurocognitive processes supporting language and evolutionarily conserved, domain-general processes that can be traced back to our primate ancestors. Neuroimaging studies across species may determine whether can...

journal_title：Nature communications

authors： Wilson B,Kikuchi Y,Sun L,Hunter D,Dick F,Smith K,Thiele A,Griffiths TD,Marslen-Wilson WD,Petkov CI

更新日期：2015-11-17 00:00:00

abstract：:Metagenomic sequencing has greatly improved our ability to profile the composition of environmental and host-associated microbial communities. However, the dependency of most methods on reference genomes, which are currently unavailable for a substantial fraction of microbial species, introduces estimation biases. We ...

journal_title：Nature communications

authors： Milanese A,Mende DR,Paoli L,Salazar G,Ruscheweyh HJ,Cuenca M,Hingamp P,Alves R,Costea PI,Coelho LP,Schmidt TSB,Almeida A,Mitchell AL,Finn RD,Huerta-Cepas J,Bork P,Zeller G,Sunagawa S

更新日期：2019-03-04 00:00:00

abstract：:Modelling of non-adiabatic dynamics in extended molecular systems and solids is a next frontier of atomistic electronic structure theory. The underlying numerical algorithms should operate only with a few quantities (that can be efficiently obtained from quantum chemistry), provide a controlled approximation (which ca...

journal_title：Nature communications

authors： Gorshkov VN,Tretiak S,Mozyrsky D

更新日期：2013-01-01 00:00:00

abstract：:Identifying regions important for spreading and mediating perturbations is crucial to assess the susceptibilities of spatio-temporal complex systems such as the Earth's climate to volcanic eruptions, extreme events or geoengineering. Here a data-driven approach is introduced based on a dimension reduction, causal reco...

journal_title：Nature communications

authors： Runge J,Petoukhov V,Donges JF,Hlinka J,Jajcay N,Vejmelka M,Hartman D,Marwan N,Paluš M,Kurths J

更新日期：2015-10-07 00:00:00

abstract：:Peptide macrocycles are promising therapeutic molecules because they are protease resistant, structurally rigid, membrane permeable, and capable of modulating protein-protein interactions. Here, we report the characterization of the dual function macrocyclase-peptidase enzyme involved in the biosynthesis of the highly...

journal_title：Nature communications

authors： Czekster CM,Ludewig H,McMahon SA,Naismith JH

更新日期：2017-10-19 00:00:00

abstract：:Despite tremendous importance in catalysis, the design of oxide-metal interface has been hampered by the limited understanding of the nature of interfacial sites and the oxide-metal interaction (OMI). Through construction of well-defined Cu2O/Pt, Cu2O/Ag and Cu2O/Au interfaces, we find that Cu2O nanostructures (NSs) o...

journal_title：Nature communications

authors： Huang W,Liu Q,Zhou Z,Li Y,Ling Y,Wang Y,Tu Y,Wang B,Zhou X,Deng D,Yang B,Yang Y,Liu Z,Bao X,Yang F

更新日期：2020-05-08 00:00:00

abstract：:In all of the diverse areas of science where waves play an important role, one of the most fundamental solutions of the corresponding wave equation is a stationary wave with constant intensity. The most familiar example is that of a plane wave propagating in free space. In the presence of any Hermitian potential, a wa...

journal_title：Nature communications

authors： Makris KG,Musslimani ZH,Christodoulides DN,Rotter S

更新日期：2015-07-08 00:00:00

abstract：:The emergence of artificial intelligence (AI) and its progressively wider impact on many sectors requires an assessment of its effect on the achievement of the Sustainable Development Goals. Using a consensus-based expert elicitation process, we find that AI can enable the accomplishment of 134 targets across all the ...

journal_title：Nature communications

authors： Vinuesa R,Azizpour H,Leite I,Balaam M,Dignum V,Domisch S,Felländer A,Langhans SD,Tegmark M,Fuso Nerini F

更新日期：2020-01-13 00:00:00