Biomimetic design of iridescent insect cuticles with tailored, self-organized cholesteric patterns.

abstract：:The demand for highly scalable, low-power devices for data storage and logic operations is strongly stimulating research into resistive switching as a novel concept for future non-volatile memory devices. To meet technological requirements, it is imperative to have a set of material design rules based on fundamental m...

journal_title：Nature communications

authors： Baeumer C,Schmitz C,Ramadan AH,Du H,Skaja K,Feyer V,Müller P,Arndt B,Jia CL,Mayer J,De Souza RA,Michael Schneider C,Waser R,Dittmann R

更新日期：2015-10-19 00:00:00

abstract：:Detection of microbial components such as lipopolysaccharide (LPS) by Toll-like receptor 4 (TLR4) on macrophages induces a robust pro-inflammatory response that is dependent on metabolic reprogramming. These innate metabolic changes have been compared to aerobic glycolysis in tumour cells. However, the mechanisms by w...

journal_title：Nature communications

authors： Balic JJ,Albargy H,Luu K,Kirby FJ,Jayasekara WSN,Mansell F,Garama DJ,De Nardo D,Baschuk N,Louis C,Humphries F,Fitzgerald K,Latz E,Gough DJ,Mansell A

更新日期：2020-07-30 00:00:00

abstract：:Folding processes play a crucial role in the development of function in biomacromolecules. Recreating this feature on synthetic systems would not only allow understanding and reproducing biological functions but also developing new functions. This has inspired the development of conformationally ordered synthetic olig...

journal_title：Nature communications

authors： Carini M,Ruiz MP,Usabiaga I,Fernández JA,Cocinero EJ,Melle-Franco M,Diez-Perez I,Mateo-Alonso A

更新日期：2017-05-18 00:00:00

abstract：:The term tunnel electroresistance (TER) denotes a fast, non-volatile, reversible resistance switching triggered by voltage pulses in ferroelectric tunnel junctions. It is explained by subtle mechanisms connected to the voltage-induced reversal of the ferroelectric polarization. Here we demonstrate that effects functio...

journal_title：Nature communications

authors： Rouco V,Hage RE,Sander A,Grandal J,Seurre K,Palermo X,Briatico J,Collin S,Trastoy J,Bouzehouane K,Buzdin AI,Singh G,Bergeal N,Feuillet-Palma C,Lesueur J,Leon C,Varela M,Santamaría J,Villegas JE

更新日期：2020-01-31 00:00:00

abstract：:Disordered mechanical systems, when strongly deformed, have complex configuration spaces with multiple stable states and pathways connecting them. The topology of such pathways determines which states are smoothly accessible from any part of configuration space. Controlling this topology would allow us to limit access...

journal_title：Nature communications

authors： Stern M,Jayaram V,Murugan A

更新日期：2018-10-16 00:00:00

abstract：:Genetic studies of Neolithic and Bronze Age skeletons from Europe have provided evidence for strong population genetic changes at the beginning and the end of the Neolithic period. To further understand the implications of these in Southern Central Europe, we analyze 96 ancient genomes from Switzerland, Southern Germa...

journal_title：Nature communications

authors： Furtwängler A,Rohrlach AB,Lamnidis TC,Papac L,Neumann GU,Siebke I,Reiter E,Steuri N,Hald J,Denaire A,Schnitzler B,Wahl J,Ramstein M,Schuenemann VJ,Stockhammer PW,Hafner A,Lösch S,Haak W,Schiffels S,Krause J

更新日期：2020-04-20 00:00:00

abstract：:To fulfill its role in protein biogenesis, the endoplasmic reticulum (ER) depends on the Hsp70-type molecular chaperone BiP, which requires a constant ATP supply. However, the carrier that catalyzes ATP uptake into the ER was unknown. Here, we report that our screen of gene expression datasets for member(s) of the fam...

journal_title：Nature communications

authors： Klein MC,Zimmermann K,Schorr S,Landini M,Klemens PAW,Altensell J,Jung M,Krause E,Nguyen D,Helms V,Rettig J,Fecher-Trost C,Cavalié A,Hoth M,Bogeski I,Neuhaus HE,Zimmermann R,Lang S,Haferkamp I

更新日期：2018-08-28 00:00:00

abstract：:Organic-inorganic hybrid perovskites are promising candidates for the next-generation solar cells. Many efforts have been made to study their structures in the search for a better mechanistic understanding to guide the materials optimization. Here, we investigate the structure instability of the single-crystalline CH3...

journal_title：Nature communications

authors： Chen S,Zhang X,Zhao J,Zhang Y,Kong G,Li Q,Li N,Yu Y,Xu N,Zhang J,Liu K,Zhao Q,Cao J,Feng J,Li X,Qi J,Yu D,Li J,Gao P

更新日期：2018-11-15 00:00:00

abstract：:Many porous materials are damaged by pressure exerted by salt crystals growing in their pores. This is a serious issue in conservation science, geomorphology, geotechnical engineering and concrete materials science. In all cases, a central question is whether crystallization pressure will cause damage. Here we present...

journal_title：Nature communications

authors： Flatt RJ,Caruso F,Sanchez AM,Scherer GW

更新日期：2014-09-11 00:00:00

abstract：:The prefrontal cortex and striatum form a recurrent network whose spiking activity encodes multiple types of learning-relevant information. This spike-encoded information is evident in average firing rates, but finer temporal coding might allow multiplexing and enhanced readout across the connected network. We tested ...

journal_title：Nature communications

authors： Voloh B,Oemisch M,Womelsdorf T

更新日期：2020-09-16 00:00:00

abstract：:In life sciences, the material properties of suspended cells have attained significance close to that of fluorescent markers but with the advantage of label-free and unbiased sample characterization. Until recently, cell rheological measurements were either limited by acquisition throughput, excessive post processing,...

journal_title：Nature communications

authors： Fregin B,Czerwinski F,Biedenweg D,Girardo S,Gross S,Aurich K,Otto O

更新日期：2019-01-24 00:00:00

abstract：:HOXA9 and MEIS1 have essential oncogenic roles in mixed lineage leukaemia (MLL)-rearranged leukaemia. Here we show that they are direct targets of miRNA-196b, a microRNA (miRNA) located adjacent to and co-expressed with HOXA9, in MLL-rearranged leukaemic cells. Forced expression of miR-196b significantly delays MLL-fu...

journal_title：Nature communications

authors： Li Z,Huang H,Chen P,He M,Li Y,Arnovitz S,Jiang X,He C,Hyjek E,Zhang J,Zhang Z,Elkahloun A,Cao D,Shen C,Wunderlich M,Wang Y,Neilly MB,Jin J,Wei M,Lu J,Valk PJM,Delwel R,Lowenberg B,Le Beau MM,Vardiman J,M

更新日期：2012-02-21 00:00:00

abstract：:Heparin-like oligosaccharides mediate numerous important biological interactions, of which many are implicated in various diseases. Synthetic improvements are central to the development of such oligosaccharides as therapeutics and, in addition, there are no methods to elucidate the pharmacokinetics of structurally def...

journal_title：Nature communications

authors： Hansen SU,Miller GJ,Cole C,Rushton G,Avizienyte E,Jayson GC,Gardiner JM

更新日期：2013-01-01 00:00:00

abstract：:Systems-wide profiling of breast cancer has almost always entailed RNA and DNA analysis by microarray and sequencing techniques. Marked developments in proteomic technologies now enable very deep profiling of clinical samples, with high identification and quantification accuracy. We analysed 40 oestrogen receptor posi...

journal_title：Nature communications

authors： Tyanova S,Albrechtsen R,Kronqvist P,Cox J,Mann M,Geiger T

更新日期：2016-01-04 00:00:00

abstract：:Bacterial infections and antibiotic resistance, particularly by Gram-negative pathogens, have become a global healthcare crisis. We report the design of a class of cationic antimicrobial polymers that cluster local facial amphiphilicity from repeating units to enhance interactions with bacterial membranes without requ...

journal_title：Nature communications

authors： Rahman MA,Bam M,Luat E,Jui MS,Ganewatta MS,Shokfai T,Nagarkatti M,Decho AW,Tang C

更新日期：2018-12-07 00:00:00

abstract：:Analysis of potentially interconnected residential water and energy demand is sparse. In a 1-in-10 random sample of Singapore households living in apartments, water use per capita declines over the socioeconomic distribution, whereas electricity use rises. Here I show that in this leading Asian city and tropical clima...

journal_title：Nature communications

authors： Salvo A

更新日期：2018-12-20 00:00:00

abstract：:Targeted insertion of transgenes at pre-determined plant genomic safe harbors provides a desirable alternative to insertions at random sites achieved through conventional methods. Most existing cases of targeted gene insertion in plants have either relied on the presence of a selectable marker gene in the insertion ca...

journal_title：Nature communications

authors： Dong OX,Yu S,Jain R,Zhang N,Duong PQ,Butler C,Li Y,Lipzen A,Martin JA,Barry KW,Schmutz J,Tian L,Ronald PC

更新日期：2020-03-04 00:00:00

abstract：:Foldamers provide an attractive medium to test the mechanisms by which biological macromolecules fold into complex three-dimensional structures, and ultimately to design novel protein-like architectures with properties unprecedented in nature. Here, we describe a large cage-like structure formed from an amphiphilic ar...

journal_title：Nature communications

authors： Pavone V,Zhang SQ,Merlino A,Lombardi A,Wu Y,DeGrado WF

更新日期：2014-04-07 00:00:00

abstract：:Longevity is influenced by genetic and environmental factors, but the underlying mechanisms remain elusive. Here, we functionally characterise a Drosophila small nucleolar RNA (snoRNA), named jouvence whose loss of function reduces lifespan. The genomic region of jouvence rescues the longevity in mutant, while its ove...

journal_title：Nature communications

authors： Soulé S,Mellottée L,Arab A,Chen C,Martin JR

更新日期：2020-02-20 00:00:00

abstract：:Alcohol oxidation reactions are widely used for the preparation of aldehydes and ketones. The electrolysis of alcohols to carbonyl compounds have been underutilized owing to low efficiency. Herein, we report an electrochemical oxidation of various alcohols in a continuous-flow reactor without external oxidants, base o...

journal_title：Nature communications

authors： Wang D,Wang P,Wang S,Chen YH,Zhang H,Lei A

更新日期：2019-06-26 00:00:00

abstract：:Cancer is caused by the accumulation of multiple genetic mutations, but their cooperative effects are poorly understood. Using a genome-wide analysis of all the somatic mutations in colorectal cancer patients in a large-scale molecular interaction network, here we find that a giant cluster of mutation-propagating modu...

journal_title：Nature communications

authors： Shin D,Lee J,Gong JR,Cho KH

更新日期：2017-11-02 00:00:00

abstract：:Understanding catalysts strain dynamic behaviours is crucial for the development of cost-effective, efficient, stable and long-lasting catalysts. Here, we reveal in situ three-dimensional strain evolution of single gold nanocrystals during a catalytic CO oxidation reaction under operando conditions with coherent X-ray...

journal_title：Nature communications

authors： Passos AR,Rochet A,Manente LM,Suzana AF,Harder R,Cha W,Meneau F

更新日期：2020-09-18 00:00:00

abstract：:Transient precursor states are often experimentally observed for molecules adsorbing on surfaces. However, such precursor states are typically rather short-lived, quickly yielding to more stable adsorption configurations. Here we employ first-principles calculations to systematically explore the interaction mechanism ...

journal_title：Nature communications

authors： Liu W,Filimonov SN,Carrasco J,Tkatchenko A

更新日期：2013-01-01 00:00:00

abstract：:Many bacteria and most archaea possess a crystalline protein surface layer (S-layer), which surrounds their growing and topologically complicated outer surface. Constructing a macromolecular structure of this scale generally requires localized enzymatic machinery, but a regulatory framework for S-layer assembly has no...

journal_title：Nature communications

authors： Comerci CJ,Herrmann J,Yoon J,Jabbarpour F,Zhou X,Nomellini JF,Smit J,Shapiro L,Wakatsuki S,Moerner WE

更新日期：2019-06-21 00:00:00

abstract：:The JmjC histone demethylases (KDMs) are linked to tumour cell proliferation and are current cancer targets; however, very few highly selective inhibitors for these are available. Here we report cyclic peptide inhibitors of the KDM4A-C with selectivity over other KDMs/2OG oxygenases, including closely related KDM4D/E ...

journal_title：Nature communications

authors： Kawamura A,Münzel M,Kojima T,Yapp C,Bhushan B,Goto Y,Tumber A,Katoh T,King ON,Passioura T,Walport LJ,Hatch SB,Madden S,Müller S,Brennan PE,Chowdhury R,Hopkinson RJ,Suga H,Schofield CJ

更新日期：2017-04-06 00:00:00

abstract：:As academic careers become more competitive, junior scientists need to understand the value that mentorship brings to their success in academia. Previous research has found that, unsurprisingly, successful mentors tend to train successful students. But what characteristics of this relationship predict success, and how...

journal_title：Nature communications

authors： Liénard JF,Achakulvisut T,Acuna DE,David SV

更新日期：2018-11-27 00:00:00

abstract：:Thin-film oxide heterostructures show great potential for use in spintronic memories, where electronic charge and spin are coupled to transport information. Here we use a La0.7Sr0.3MnO3 (LSMO)/PbZr0.2Ti0.8O3 (PZT) model system to explore how local variations in electronic and magnetic phases mediate this coupling. We ...

journal_title：Nature communications

authors： Spurgeon SR,Balachandran PV,Kepaptsoglou DM,Damodaran AR,Karthik J,Nejati S,Jones L,Ambaye H,Lauter V,Ramasse QM,Lau KKS,Martin LW,Rondinelli JM,Taheri ML

更新日期：2015-04-16 00:00:00

abstract：:While plasmonic designs have dominated recent trends in structural color, schemes using localized surface plasmon resonances and surface plasmon polaritons that simultaneously achieve high color vibrancy at ultrahigh resolution have been elusive because of tradeoffs between size and performance. Herein we demonstrate ...

journal_title：Nature communications

authors： Lee JS,Park JY,Kim YH,Jeon S,Ouellette O,Sargent EH,Kim DH,Hyun JK

更新日期：2019-10-21 00:00:00

abstract：:Stimuli-responsive behaviors of flexible metal-organic frameworks (MOFs) make these materials promising in a wide variety of applications such as gas separation, drug delivery, and molecular sensing. Considerable efforts have been made over the last decade to understand the structural changes of flexible MOFs in respo...

journal_title：Nature communications

authors： Zhao P,Fang H,Mukhopadhyay S,Li A,Rudić S,McPherson IJ,Tang CC,Fairen-Jimenez D,Tsang SCE,Redfern SAT

更新日期：2019-03-01 00:00:00

abstract：:The identification of fractionalized excitations, such as Majorana quasi-particles, would be a striking signal of the realization of exotic quantum states of matter. While the paramount demonstration of such excitations would be a probe of their non-Abelian statistics via controlled braiding operations, alternative pr...

journal_title：Nature communications

authors： Laflamme C,Budich JC,Zoller P,Dalmonte M

更新日期：2016-08-02 00:00:00