NADH Ties One-Carbon Metabolism to Cellular Respiration.

Abstract:

:In this issue of Cell Metabolism, Yang et al., 2020 report that serine is a source of mitochondrial NADH derived from one-carbon metabolism. Serine becomes a major source of NADH when cellular respiration is inhibited, and the un-utilized, accumulated NADH inhibits the TCA cycle and slows proliferation.

journal_name

Cell Metab

journal_title

Cell metabolism

authors

Maynard AG,Kanarek N

doi

10.1016/j.cmet.2020.03.012

subject

Has Abstract

pub_date

2020-04-07 00:00:00

pages

660-662

issue

4

eissn

1550-4131

issn

1932-7420

pii

S1550-4131(20)30127-3

journal_volume

31

pub_type

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