Intestinal Alkaline Phosphatase Exerts Anti-Inflammatory Effects Against Lipopolysaccharide by Inducing Autophagy.

abstract：:N(1)-methyladenosine (m(1)A) is a prominent RNA modification involved in many biological processes. Accurate identification of m(1)A site is invaluable for better understanding the biological functions of m(1)A. However, limitations in experimental methods preclude the progress towards the identification of m(1)A site...

journal_title：Scientific reports

authors： Chen W,Feng P,Tang H,Ding H,Lin H

更新日期：2016-08-11 00:00:00

abstract：:Biological control mechanisms of plant diseases have been intensively studied. However, how plant pathogens respond to and resist or alleviate biocontrol agents remains largely unknown. In this study, a comparative transcriptome analysis was performed to elucidate how the pathogen of sclerotinia stem rot, Sclerotinia ...

journal_title：Scientific reports

authors： Yang X,Zhang L,Xiang Y,Du L,Huang X,Liu Y

更新日期：2020-07-28 00:00:00

abstract：:Aging is a highly controlled biological process characterized by a progressive deterioration of various cellular activities. One of several hallmarks of aging describes a link to transcriptional alteration, suggesting that it may impact the steady-state mRNA levels. We analyzed the mRNA steady-state levels of polyCAG-...

journal_title：Scientific reports

authors： Adamla F,Ignatova Z

更新日期：2015-06-02 00:00:00

abstract：:A microfluidic probe (MFP) is a mobile channel-less microfluidic system under which a fluid is injected from an aperture into an open space, hydrodynamically confined by a surrounding fluid, and entirely re-aspirated into a second aperture. Various MFPs have been developed, and have been used for applications ranging ...

journal_title：Scientific reports

authors： Safavieh M,Qasaimeh MA,Vakil A,Juncker D,Gervais T

更新日期：2015-07-14 00:00:00

abstract：:Emergence of new molecules acting directly on the hepatitic C virus (HCV) has improved treatment outcomes. However, there is a risk of selecting viral escape mutants, so a new combination is needed using different inhibitors that target different steps of the HCV infectious cycle. Novel single tablet formulations were...

journal_title：Scientific reports

authors： Shiha G,Soliman R,Elbasiony M,Darwish NHE,Mousa SA

更新日期：2019-09-19 00:00:00

abstract：:NLRP3 inflammasomes recognize non-microbial danger signals and induce release of proinflammatory cytokine interleukin (IL)-1β, leading to sterile inflammation in cardiovascular disease. Because sterile inflammation is involved in doxorubicin (Dox)-induced cardiotoxicity, we investigated the role of NLRP3 inflammasomes...

journal_title：Scientific reports

authors： Kobayashi M,Usui F,Karasawa T,Kawashima A,Kimura H,Mizushina Y,Shirasuna K,Mizukami H,Kasahara T,Hasebe N,Takahashi M

更新日期：2016-05-26 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Seo YS,Eom MJ,Kim JS,Kang CJ,Min BI,Hwang J

更新日期：2020-03-03 00:00:00

abstract：:A novel ignition hohlraum for indirect-drive inertial confinement fusion is proposed, which is named three-axis cylindrical hohlraum (TACH). TACH is a kind of 6 laser entrance holes (LEHs) hohlraum, which is orthogonally jointed of three cylindrical hohlraums. Laser beams are injected through every entrance hole with ...

journal_title：Scientific reports

authors： Kuang L,Li H,Jing L,Lin Z,Zhang L,Li L,Ding Y,Jiang S,Liu J,Zheng J

更新日期：2016-10-05 00:00:00

abstract：:MicroRNAs (miRNAs) are noncoding RNAs which control gene expression by the suppression of translation or the degradation of mRNAs. Dre-miR-21 (miR-21) has been reported to impact cardiac valvulogenesis in zebrafish embryos. However, the target genes of miR-21 are still largely unknown. Here a tandem isobaric mass tag ...

journal_title：Scientific reports

authors： Wu Y,Lou QY,Ge F,Xiong Q

更新日期：2017-06-22 00:00:00

abstract：:Activated sludge granules and flocs have their inherent advantages and disadvantages for wastewater treatment due to their different characteristics. So far quantitative information on their evaluation is still lacking. This work provides a quantitative and comparative evaluation on the characteristics and pollutant r...

journal_title：Scientific reports

authors： Fang F,Qiao LL,Ni BJ,Cao JS,Yu HQ

更新日期：2017-02-17 00:00:00

abstract：:Staphylococcus epidermidis is the predominant cause of recalcitrant biofilm-associated infections, which are often highly resistant to antibiotics. Thus, the use of physico-chemical agents for disinfection offers a more effective approach to the control of S. epidermidis biofilm infections. However, the underlying tol...

journal_title：Scientific reports

authors： Olwal CO,Ang'ienda PO,Ochiel DO

更新日期：2019-03-29 00:00:00

abstract：:Three H10 subtype avian influenza viruses were isolated from domestic ducks in China, designated as SH602/H10N8, FJ1761/H10N3 and SX3180/H10N7, with an intravenous pathogenicity index (IVPI) of 0.39, 1.60, and 1.27, respectively. These H10 viruses showed a complex pathology pattern in different species, although full ...

journal_title：Scientific reports

authors： Zhang M,Zhang X,Xu K,Teng Q,Liu Q,Li X,Yang J,Xu J,Chen H,Zhang X,Li Z

更新日期：2016-09-28 00:00:00

abstract：:Epithelial ovarian cancer is a leading cause of death in gynecological cancers. While several systematic studies have revealed the mutation landscape of serous epithelial ovarian cancer, other non-serous subtypes of the disease have not been explored as extensively. Here we conduct exome sequencing of nine non-serous ...

journal_title：Scientific reports

authors： Teer JK,Yoder S,Gjyshi A,Nicosia SV,Zhang C,Monteiro ANA

更新日期：2017-08-29 00:00:00

abstract：:Nature within cities will have a central role in helping address key global public health challenges associated with urbanization. However, there is almost no guidance on how much or how frequently people need to engage with nature, and what types or characteristics of nature need to be incorporated in cities for the ...

journal_title：Scientific reports

authors： Shanahan DF,Bush R,Gaston KJ,Lin BB,Dean J,Barber E,Fuller RA

更新日期：2016-06-23 00:00:00

abstract：:Capable of mediating efficient transfection and protein production without eliciting innate immune responses, chemically modified mRNA holds great potential to produce paracrine factors at a physiologically beneficial level, in a spatiotemporally controlled manner, and with low toxicity. Although highly promising in c...

journal_title：Scientific reports

authors： Sun N,Ning B,Hansson KM,Bruce AC,Seaman SA,Zhang C,Rikard M,DeRosa CA,Fraser CL,Wågberg M,Fritsche-Danielson R,Wikström J,Chien KR,Lundahl A,Hölttä M,Carlsson LG,Peirce SM,Hu S

更新日期：2018-11-30 00:00:00

abstract：:Accurate detection of accelerometer non-wear time is crucial for calculating physical activity summary statistics. In this study, we evaluated three epoch-based non-wear algorithms (Hecht, Troiano, and Choi) and one raw-based algorithm (Hees). In addition, we performed a sensitivity analysis to provide insight into th...

journal_title：Scientific reports

authors： Syed S,Morseth B,Hopstock LA,Horsch A

更新日期：2020-04-03 00:00:00

abstract：:Histone acetylation has been linked to cardiac hypertrophy and heart failure. However, the pathological implications of changes in histone methylation and the effects of interventions with histone methyltransferase inhibitors for heart failure have not been fully clarified. Here, we focused on H3K9me3 status in the he...

journal_title：Scientific reports

authors： Ono T,Kamimura N,Matsuhashi T,Nagai T,Nishiyama T,Endo J,Hishiki T,Nakanishi T,Shimizu N,Tanaka H,Ohta S,Suematsu M,Ieda M,Sano M,Fukuda K,Kaneda R

更新日期：2017-01-04 00:00:00

abstract：:Chronic hepatitis B infection remains a serious public health issue worldwide. Hepatitis B virus (HBV) reactivation is commonly reported in patients receiving anticancer therapy, immunosuppressive therapy, or organ and tissue transplantation. However, the precise mechanisms underlying chemotherapeutic agent-related HB...

journal_title：Scientific reports

authors： Li X,Pan E,Zhu J,Xu L,Chen X,Li J,Liang L,Hu Y,Xia J,Chen J,Chen W,Hu J,Wang K,Tang N,Huang A

更新日期：2018-02-22 00:00:00

abstract：:Accumulating evidence indicates that cancer cells show specific alterations in phospholipid metabolism that contribute to tumour progression in several types of cancer, including colorectal cancer. Questions still remain as to what lipids characterize the outer edge of cancer tissues and whether those cancer outer edg...

journal_title：Scientific reports

authors： Hiraide T,Ikegami K,Sakaguchi T,Morita Y,Hayasaka T,Masaki N,Waki M,Sugiyama E,Shinriki S,Takeda M,Shibasaki Y,Miyazaki S,Kikuchi H,Okuyama H,Inoue M,Setou M,Konno H

更新日期：2016-07-20 00:00:00

abstract：:Luminance plays a modulating role in the processes of several visual tasks, which in turn provides significant information for the understanding of visual processing. Here, using a binocular phase combination paradigm, we studied the effect of unilateral changes in mean luminance on binocular combination in both norma...

journal_title：Scientific reports

authors： Zhou J,Jia W,Huang CB,Hess RF

更新日期：2013-01-01 00:00:00

abstract：:Beta oscillations observed in motor cortical local field potentials (LFPs) recorded on separate electrodes of a multi-electrode array have been shown to exhibit non-zero phase shifts that organize into planar waves. Here, we generalize this concept to additional classes of salient patterns that fully describe the spat...

journal_title：Scientific reports

authors： Denker M,Zehl L,Kilavik BE,Diesmann M,Brochier T,Riehle A,Grün S

更新日期：2018-03-26 00:00:00

abstract：:Among patients with non-small cell lung cancer (NSCLC), best supportive care (BSC) is well-known to improve patient's quality of life and prolong survival. This study aimed to clarify (1) the decision-making factors of BSC alone and (2) the prognostic factors after selection of no further anticancer therapies. We retr...

journal_title：Scientific reports

authors： Kitazawa H,Takeda Y,Naka G,Sugiyama H

更新日期：2019-12-27 00:00:00

abstract：:The manuscript highlights the efficacy of silver ions to act as a unique probe for the detection of bacterial contamination in water samples. The bacterial cell membrane adherence property of the silver ions was employed to develop two different bacterial detection assays employing colorimetric and electrochemical tec...

journal_title：Scientific reports

authors： Kumar V,Chopra A,Bisht B,Bhalla V

更新日期：2020-07-20 00:00:00

abstract：:Mucociliary clearance is a biomechanical mechanism of airway protection. It consists of the active transport along the bronchial tree of the mucus, a fluid propelled by the coordinated beating of a myriad of cilia on the epithelial surface of the respiratory tract. The physics of mucus transport is poorly understood b...

journal_title：Scientific reports

authors： Khelloufi MK,Loiseau E,Jaeger M,Molinari N,Chanez P,Gras D,Viallat A

更新日期：2018-02-05 00:00:00

abstract：:In the field of neuroprosthetics, the current state-of-the-art method involves controlling the prosthesis with electromyography (EMG) or electrooculography/electroencephalography (EOG/EEG). However, these systems are both expensive and time consuming to calibrate, susceptible to interference, and require a lengthy lea...

journal_title：Scientific reports

authors： Hazubski S,Hoppe H,Otte A

更新日期：2020-10-01 00:00:00

abstract：:Human papillomavirus (HPV) infection, a primary cause of genital cancer, is also related to the increasing incidence of oropharyngeal cancer among young men. Relatively little is known about the concurrence of oral and genital infection among healthy individuals. Oral and genital swab exfoliated cells were collected s...

journal_title：Scientific reports

authors： Liu F,Hang D,Deng Q,Liu M,Xi L,He Z,Zhang C,Sun M,Liu Y,Li J,Pan Y,Ning T,Guo C,Liang Y,Xu R,Zhang L,Cai H,Ke Y

更新日期：2015-10-27 00:00:00

abstract：:Ancient statues are usually fragile and have a tendency to deteriorate over time, developing cracks, corrosion, and losing color. Before any intervention on the object of art, a conservator must map degradation and take measurements. Deterioration mapping is an extremely long process, as the conservator or restorer mu...

journal_title：Scientific reports

authors： Nasri A,Huang X

更新日期：2020-12-14 00:00:00

abstract：:Liver regeneration is a spontaneous process that occurs after liver injury, but acute liver failure is a complex and fatal disease which is difficult to treat. Cell-based therapies are promising alternative therapeutic approach for liver failure and different cell sources have been tested in this regard. We investigat...

journal_title：Scientific reports

authors： Kumar A,Kumar V,Rattan V,Jha V,Pal A,Bhattacharyya S

更新日期：2017-11-08 00:00:00

abstract：:Astragalus membranaceus (HUANG QI, HQ) is a kind of traditional Chinese medicine. Researchers have widely concerned its antitumor effect. At present, there is still a lack of research on the treatment of laryngeal cancer with HQ. In this study, we integrated data from the weighted gene co-expression network of larynge...

journal_title：Scientific reports

authors： Dong KF,Huo MQ,Sun HY,Li TK,Li D

更新日期：2020-07-07 00:00:00

abstract：:Space radiation brings uneven damages to cells. The detection of the distribution of cell damage plays a very important role in radiation medicine and the related research. In this paper, a new hand-held microfluidic flow cytometer was developed to evaluate the degree of radiation damage of cells. The device we propos...

journal_title：Scientific reports

authors： Wang J,Fan Z,Zhao Y,Song Y,Chu H,Song W,Song Y,Pan X,Sun Y,Li D

更新日期：2016-03-17 00:00:00