Two-Aperture Microfluidic Probes as Flow Dipole: Theory and Applications.

abstract：:Escherichia coli and Salmonella Enteritidis are foodborne pathogens forming challenging biofilms that contribute to their virulence, antimicrobial resistance, and survival on surfaces. Interspecies interactions occur between species in mixed biofilms promoting different outcomes to each species. Here we describe the i...

journal_title：Scientific reports

authors： Milho C,Silva MD,Alves D,Oliveira H,Sousa C,Pastrana LM,Azeredo J,Sillankorva S

更新日期：2019-12-03 00:00:00

abstract：:Although cisplatin plays a central role in cancer chemotherapy, the mechanisms of cell response to this drug have been unexplored. The present study demonstrates the relationships between the intracellular pH (pHi), cell bioenergetics and the response of cervical cancer to cisplatin. pHi was measured using genetically...

journal_title：Scientific reports

authors： Shirmanova MV,Druzhkova IN,Lukina MM,Dudenkova VV,Ignatova NI,Snopova LB,Shcheslavskiy VI,Belousov VV,Zagaynova EV

更新日期：2017-08-21 00:00:00

abstract：:Circadian clocks keep time via ~ 24 h transcriptional feedback loops. In Drosophila, CLOCK-CYCLE (CLK-CYC) activators and PERIOD-TIMELESS (PER-TIM) repressors are feedback loop components whose transcriptional status varies over a circadian cycle. Although changes in the state of activators and repressors has been cha...

journal_title：Scientific reports

authors： Mahesh G,Rivas GBS,Caster C,Ost EB,Amunugama R,Jones R,Allen DL,Hardin PE

更新日期：2020-10-21 00:00:00

abstract：:In many vertebrates, acoustic cues to body size are encoded in resonance frequencies of the vocal tract ("formants"), rather than in the rate of tissue vibration in the sound source ("pitch"). Anatomical constraints on the vocal tract's size render formants honest cues to size in many bird and mammal species, but it i...

journal_title：Scientific reports

authors： Reber SA,Janisch J,Torregrosa K,Darlington J,Vliet KA,Fitch WT

更新日期：2017-05-12 00:00:00

abstract：:The transparency of animals is an important biological feature. Ascidian eggs have various degrees of transparency, but this characteristic has not yet been measured quantitatively and comprehensively. In this study, we established a method for evaluating the transparency of eggs to first characterize the transparency...

journal_title：Scientific reports

authors： Shito TT,Hasegawa N,Oka K,Hotta K

更新日期：2020-11-30 00:00:00

abstract：:The definition of a precise illumination region is essential in many applications where the electromagnetic field should be confined in some specific volume. By using conventional structures, it is difficult to achieve an adequate confinement distance (or volume) with negligible levels of radiation leakage beyond it. ...

journal_title：Scientific reports

authors： Bonache J,Zamora G,Paredes F,Zuffanelli S,Aguilà P,Martín F

更新日期：2016-11-25 00:00:00

abstract：:Ball-milling utilizes mechanical stress to modify properties of carbon nanotubes (CNTs) including size, capping, and functionalization. Ball-milling, however, may introduce structural defects resulting in altered CNT-biomolecule interactions. Nanomaterial-biomolecule interactions result in the formation of the biocoro...

journal_title：Scientific reports

authors： Raghavendra AJ,Fritz K,Fu S,Brown JM,Podila R,Shannahan JH

更新日期：2017-08-16 00:00:00

abstract：:Crosstalk between phytohormone pathways is essential in plant growth, development and stress responses. Brassinosteroids (BRs) and ethylene are both pivotal plant growth regulators, and the interaction between these two phytohormones in the tomato response to salt stress is still unclear. Here, we explored the mechani...

journal_title：Scientific reports

authors： Zhu T,Deng X,Zhou X,Zhu L,Zou L,Li P,Zhang D,Lin H

更新日期：2016-10-14 00:00:00

abstract：:Dengue virus (DENV) infects 400 million people worldwide annually. Infection of more than one serotype of DENV highly corresponds to dengue hemorrhagic fever and dengue shock syndrome, which are the leading causes of high mortality. Due to lack of effective vaccines and unavailable therapies against DENV, discovery of...

journal_title：Scientific reports

authors： Yu JS,Wu YH,Tseng CK,Lin CK,Hsu YC,Chen YH,Lee JC

更新日期：2017-03-24 00:00:00

abstract：:Vaginal microbiota is an important early source of bacterial colonization for newborns. However, only a few small studies have investigated the composition of vaginal microbiota during labor. In this work, we analyzed vaginal swabs collected at 36 weeks gestation and at the onset of labor from 256 women participating ...

journal_title：Scientific reports

authors： Avershina E,Slangsvold S,Simpson MR,Storrø O,Johnsen R,Øien T,Rudi K

更新日期：2017-12-14 00:00:00

abstract：:Evaluation of the effect of different parameters for designing a non-viral vector in gene delivery systems has great importance. In this manner, 2D crystals, precisely layered double hydroxides, have attracted the attention of scientists due to their significant adjustability and low-toxicity and low-cost preparation ...

journal_title：Scientific reports

authors： Rabiee N,Bagherzadeh M,Ghadiri AM,Salehi G,Fatahi Y,Dinarvand R

更新日期：2020-11-26 00:00:00

abstract：:Excessive activation of inflammation and the accompanying lung vascular endothelial barrier disruption are primary pathogenic features of acute lung injury (ALI). Microtubule-associated protein 4 (MAP4), a tubulin assembly-promoting protein, is important for maintaining the microtubule (MT) cytoskeleton and cell-cell ...

journal_title：Scientific reports

authors： Li L,Hu J,He T,Zhang Q,Yang X,Lan X,Zhang D,Mei H,Chen B,Huang Y

更新日期：2015-03-09 00:00:00

abstract：:The importance of metallurgy for social and economic development is indisputable. Although copper (Cu) was essential for the wealth of pre- and post-colonial societies in the Andes, the onset of extensive Cu metallurgy in South America is still debated. Comprehensive archaeological findings point to first sophisticate...

journal_title：Scientific reports

authors： Eichler A,Gramlich G,Kellerhals T,Tobler L,Rehren T,Schwikowski M

更新日期：2017-01-31 00:00:00

abstract：:Estradiol derived from neural aromatization of testosterone plays a key role in the organization and activation of neural structures underlying male behaviors. This study evaluated the contribution of the estrogen receptor (ER) β in estradiol-induced modulation of social and mood-related behaviors by using mice lackin...

journal_title：Scientific reports

authors： Dombret C,Naulé L,Trouillet AC,Parmentier C,Hardin-Pouzet H,Mhaouty-Kodja S

更新日期：2020-04-10 00:00:00

abstract：:The seven-helical bundle of rhodopsin and other G-protein coupled receptors undergoes structural rearrangements as the transmembrane receptor protein is activated. These structural changes are known to involve tilting and bending of various transmembrane helices. However, the cause and effect relationship among struct...

journal_title：Scientific reports

authors： Ren Z,Ren PX,Balusu R,Yang X

更新日期：2016-09-23 00:00:00

abstract：:Transcriptional coactivator PGC-1α and its splice variant NT-PGC-1α play crucial roles in regulating cold-induced thermogenesis in brown adipose tissue (BAT). PGC-1α and NT-PGC-1α are highly induced by cold in BAT and subsequently bind to and coactivate many transcription factors to regulate expression of genes involv...

journal_title：Scientific reports

authors： Chang JS,Ghosh S,Newman S,Salbaum JM

更新日期：2018-05-18 00:00:00

abstract：:Although more than 1,000 androgen receptor (AR) mutations have been identified and these mutants are pathologically important, few theoretical studies have investigated the role of AR protein folding stability in disease and its relationship with the phenotype of the patients. Here, we extracted AR variant data from f...

journal_title：Scientific reports

authors： Chen F,Chen X,Jiang F,Leng F,Liu W,Gui Y,Yu J

更新日期：2020-07-21 00:00:00

abstract：:The favourable kinetics of 18F-fluoro-2-deoxyglucose (FDG) permits to depict cancer glucose consumption by a single evaluation of late tracer uptake. This standard procedure relies on the slow radioactivity loss, usually attributed to the limited tumour expression of G6P-phosphatase (G6Pase). However, this classical i...

journal_title：Scientific reports

authors： Scussolini M,Bauckneht M,Cossu V,Bruno S,Orengo AM,Piccioli P,Capitanio S,Yosifov N,Ravera S,Morbelli S,Piana M,Sambuceti G,Caviglia G,Marini C

更新日期：2019-02-26 00:00:00

abstract：:Methanol (MOH) and monomethylamine (MMA) are two typical one-carbon (C1) compounds found in natural environments. They play an important role in marine and atmospheric chemistry, cloud formation, and global climate. The main biological sink of MOH and MMA is rapid consumption by marine microbes. Here, field-based time...

journal_title：Scientific reports

authors： Deng W,Peng L,Jiao N,Zhang Y

更新日期：2018-10-18 00:00:00

abstract：:Brain-computer interface (BCI) systems having the ability to classify brain waves with greater accuracy are highly desirable. To this end, a number of techniques have been proposed aiming to be able to classify brain waves with high accuracy. However, the ability to classify brain waves and its implementation in real-...

journal_title：Scientific reports

authors： Kumar S,Sharma A,Tsunoda T

更新日期：2019-06-24 00:00:00

abstract：:For N indistinguishable bosons or fermions impinged on a M-port Haar-random unitary network the average probability to count n 1, … n r particles in a small number r ≪ N of binned-together output ports takes a Gaussian form as N ≫ 1. The discovered Gaussian asymptotic law is the well-known asymptotic law for distingui...

journal_title：Scientific reports

authors： Shchesnovich VS

更新日期：2017-02-16 00:00:00

abstract：:Therapies using mesenchymal stem cell (MSC) seeded scaffolds may be applicable to various fields of regenerative medicine, including craniomaxillofacial surgery. Plastic compression of collagen scaffolds seeded with MSC has been shown to enhance the osteogenic differentiation of MSC as it increases the collagen fibril...

journal_title：Scientific reports

authors： Chamieh F,Collignon AM,Coyac BR,Lesieur J,Ribes S,Sadoine J,Llorens A,Nicoletti A,Letourneur D,Colombier ML,Nazhat SN,Bouchard P,Chaussain C,Rochefort GY

更新日期：2016-12-09 00:00:00

abstract：:In order to investigate the role of lateral angle ratio (LA ratio) and daughter artery ratio (DA ratio) for predicting aneurysmal presence in main cerebral arterial bifurcations, three-dimensional cerebral angiographic data of major cerebral artery bifurcations were used for measurement of artery diameters and bifurca...

journal_title：Scientific reports

authors： Zhang XJ,Hao WL,Zhang DH,Gao BL

更新日期：2019-11-20 00:00:00

abstract：:The GntR family transcription regulator HpaR1 identified from Xanthomonas campestris pv. campestris has been previously shown to positively regulate the genes responsible for hypersensitive reaction and pathogenicity and to autorepress its own expression. Here, we demonstrated that HpaR1 is a global regulator that pos...

journal_title：Scientific reports

authors： Su HZ,Wu L,Qi YH,Liu GF,Lu GT,Tang JL

更新日期：2016-01-28 00:00:00

abstract：:Autophagy is a lysosomal degradation pathway that plays an essential role in neuronal homeostasis and is perturbed in many neurological diseases. Transcriptional downregulation of fat was previously observed in a Drosophila model of the polyglutamine disease Dentatorubral-pallidoluysian atrophy (DRPLA) and this was sh...

journal_title：Scientific reports

authors： Baron O,Grieshober D,Dias C,Fanto M

更新日期：2019-11-06 00:00:00

abstract：:Glomerular filtration rate (GFR) assessment is indicated before every administration of cisplatin. The optimal modality for this purpose [GFR measurement by urinary Creatinine Clearance (uCrCl) versus GFR estimation (eGFR) by the CKD-EPI formula versus both] is unclear. We investigated whether eGFR only is safe in thi...

journal_title：Scientific reports

authors： Klöckl MC,Kasparek AK,Riedl JM,Moik F,Mollnar S,Stotz M,Szkandera J,Terbuch A,Gerger A,Niedrist T,Pichler M,Bauernhofer T,Schilcher G,Zitta S,Rosenkranz AR,Friedl C,Stöger H,Posch F

更新日期：2020-07-08 00:00:00

abstract：:Spinal Muscular Atrophy (SMA) is a monogenic neurodegenerative disorder and the leading genetic cause of infantile mortality. While several functions have been ascribed to the SMN (survival motor neuron) protein, their specific contribution to the disease has yet to be fully elucidated. We hypothesized that some, but ...

journal_title：Scientific reports

authors： Osman EY,Bolding MR,Villalón E,Kaifer KA,Lorson ZC,Tisdale S,Hao Y,Conant GC,Pires JC,Pellizzoni L,Lorson CL

更新日期：2019-07-01 00:00:00

abstract：:Adulterant herbal materials are a threat to consumer safety. In this study, we used DNA barcoding to investigate the proportions and varieties of adulterant species in traditional Chinese medicine (TCM) markets. We used a DNA barcode database of TCM (TCMD) that was established by our group to investigate 1436 samples ...

journal_title：Scientific reports

authors： Han J,Pang X,Liao B,Yao H,Song J,Chen S

更新日期：2016-01-07 00:00:00

abstract：:Active methane seepage occurs congruent with a high density of up to 1 km-wide and 35 m deep seafloor craters (>100 craters within 700 km2 area) within lithified sedimentary rocks in the northern Barents Sea. The crater origin has been hypothesized to be related to rapid gas hydrate dissociation and methane release ar...

journal_title：Scientific reports

authors： Waage M,Serov P,Andreassen K,Waghorn KA,Bünz S

更新日期：2020-05-21 00:00:00

abstract：:Assistive wearable soft robotic systems have recently made a surge in the field of biomedical robotics, as soft materials allow safe and transparent interactions between the users and devices. A recent interest in the field of soft pneumatic actuators (SPAs) has been the introduction of a new class of actuators called...

journal_title：Scientific reports

authors： Nguyen PH,Zhang W

更新日期：2020-06-15 00:00:00