Fat cadherins in mouse models of degenerative ataxias.

abstract：:Human KHDRBS1/Sam68 is an oncogenic splicing factor involved in signal transduction and pre-mRNA splicing. We explored the molecular mechanism of KHDRBS1 to be a prognostic marker in four different cancers. Within specific cancer, including kidney renal papillary cell carcinoma (KIRP), lung adenocarcinoma (LUAD), acut...

journal_title：Scientific reports

authors： Sumithra B,Saxena U,Das AB

更新日期：2019-07-31 00:00:00

abstract：:Selective inhibition of function-specific β-GlcNAcase has great potential in terms of drug design and biological research. The symmetrical bis-naphthalimide M-31850 was previously obtained by screening for specificity against human glycoconjugate-lytic β-GlcNAcase. Using protein-ligand co-crystallization and molecular...

journal_title：Scientific reports

authors： Liu T,Guo P,Zhou Y,Wang J,Chen L,Yang H,Qian X,Yang Q

更新日期：2014-08-26 00:00:00

abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper. ...

journal_title：Scientific reports

authors： Amano SI,Ogawa KI,Miyake Y

更新日期：2018-08-20 00:00:00

abstract：:In a short nanobearing system made from carbon nanotubes, the rotor with high rotational frequency may escape from the stator, which may cause a stability problem to the system of a nanodevice with such a nanobearing. In the present work, nanobearings with tri-walled nanotubes are investigated to reveal the conditions...

journal_title：Scientific reports

authors： Shi J,Liu LN,Cai K,Qin QH

更新日期：2017-07-28 00:00:00

abstract：:Biological validation of new radiotherapy modalities is essential to understand their therapeutic potential. Antiprotons have been proposed for cancer therapy due to enhanced dose deposition provided by antiproton-nucleon annihilation. We assessed cellular DNA damage and relative biological effectiveness (RBE) of a cl...

journal_title：Scientific reports

authors： Kavanagh JN,Currell FJ,Timson DJ,Savage KI,Richard DJ,McMahon SJ,Hartley O,Cirrone GA,Romano F,Prise KM,Bassler N,Holzscheiter MH,Schettino G

更新日期：2013-01-01 00:00:00

abstract：:The growth dynamics of Ga(In)N semiconductors by Plasma-Assisted Molecular Beam Epitaxy (PAMBE) at low temperatures (T = 450 °C) is here investigated. The presence of droplets at the growth surface strongly affects the adatom incorporation dynamics, making the growth rate a decreasing function of the metal flux imping...

journal_title：Scientific reports

authors： Azadmand M,Barabani L,Bietti S,Chrastina D,Bonera E,Acciarri M,Fedorov A,Tsukamoto S,Nötzel R,Sanguinetti S

更新日期：2018-07-26 00:00:00

abstract：:The paper presents the experimental results of studying the dynamics of electron energy relaxation in structures made of thin (d ≈ 6 nm) disordered superconducting vanadium nitride (VN) films converted to a resistive state by high-frequency radiation and transport current. Under conditions of quasi-equilibrium superco...

journal_title：Scientific reports

authors： Pentin I,Vakhtomin Y,Seleznev V,Smirnov K

更新日期：2020-10-08 00:00:00

abstract：:As it is altered by ionizing radiation, the vascular network is considered as a prime target in limiting normal tissue damage and improving tumor control in radiation therapy. Irradiation activates endothelial cells which then participate in the recruitment of circulating cells, especially by overexpressing cell adhes...

journal_title：Scientific reports

authors： Jaillet C,Morelle W,Slomianny MC,Paget V,Tarlet G,Buard V,Selbonne S,Caffin F,Rannou E,Martinez P,François A,Foulquier F,Allain F,Milliat F,Guipaud O

更新日期：2017-07-13 00:00:00

abstract：:Magnetic oscillation is a generic property of electronic conductors under magnetic fields and widely appreciated as a useful probe of their electronic band structure, i.e. the Fermi surface geometry. However, the usage of the strong static magnetic field makes the measurement insensitive to the magnetic order of the t...

journal_title：Scientific reports

authors： Fujita H,Sato M

更新日期：2018-10-24 00:00:00

abstract：:Copper ions play a vital role in a variety of fundamental physiological processes not only in human beings and plants, but also for extensive insects and microorganisms. In this paper, a novel water-soluble ruthenium(II) complex as a turn-on copper(II) ions luminescent sensor based on o-(phenylazo)aniline was designed...

journal_title：Scientific reports

authors： Zhang Y,Liu Z,Yang K,Zhang Y,Xu Y,Li H,Wang C,Lu A,Sun S

更新日期：2015-02-02 00:00:00

abstract：:Due to the limitations of current imaging techniques, visualization of lymphatic capillaries within tissue in vivo has been challenging. Here, we present a label-free high resolution optical coherence tomography (OCT) based lymphangiography (OLAG) within human skin in vivo. OLAG enables rapid (~seconds) mapping of lym...

journal_title：Scientific reports

authors： Baran U,Qin W,Qi X,Kalkan G,Wang RK

更新日期：2016-02-19 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Fülep C,Kovács I,Kránitz K,Erdei G

更新日期：2019-11-22 00:00:00

abstract：:Desmoid tumors (aggressive fibromatosis) are locally invasive soft tissue tumors that lack the ability to metastasize. There are no directed therapies or standard treatment plan, and chemotherapeutics, radiation, and surgery often have temporary effects. The majority of desmoid tumors are related to T41A and S45F muta...

journal_title：Scientific reports

authors： Mercier KA,Al-Jazrawe M,Poon R,Acuff Z,Alman B

更新日期：2018-01-12 00:00:00

abstract：:Climatic changes can induce geographic expansion and altitudinal shifts in the distribution of invasive species by offering more thermally suitable habitats. At the remote sub-Antarctic Kerguelen Islands, the predatory insect Merizodus soledadinus (Coleoptera: Carabidae), introduced in 1913, rapidly invaded coastal ha...

journal_title：Scientific reports

authors： Ouisse T,Day E,Laville L,Hendrickx F,Convey P,Renault D

更新日期：2020-01-27 00:00:00

abstract：:Pachychoroid spectrum diseases have attracted increasing attention, though their pathophysiology has yet to be fully elucidated. In this study, we assessed the vascular diameters of vortex veins in pachychoroid spectrum diseases such as central serous chorioretinopathy (CSC), pachychoroid neovasculopathy without polyp...

journal_title：Scientific reports

authors： Matsumoto H,Hoshino J,Arai Y,Mukai R,Nakamura K,Kikuchi Y,Kishi S,Akiyama H

更新日期：2020-11-11 00:00:00

abstract：:Typhoid fever poses significant burden on healthcare systems in Southeast Asia and other endemic countries. Several epidemiological and genomic studies have attributed pseudogenisation to be the major driving force for the evolution of Salmonella Typhi although its real potential remains elusive. In the present study,...

journal_title：Scientific reports

authors： Baddam R,Kumar N,Shaik S,Lankapalli AK,Ahmed N

更新日期：2014-12-12 00:00:00

abstract：:Crotoxin (CTX) is the primary toxin of South American rattlesnake Crotalus durissus terrificus venom. CTX reduces tumour mass, and tumour cell proliferation and these effects seem to involve the formation of new vessels. Angiogenesis has a key role in tumour growth and progression and is regulated by macrophage secret...

journal_title：Scientific reports

authors： de Araújo Pimenta L,de Almeida MES,Bretones ML,Cirillo MC,Curi R,Sampaio SC

更新日期：2019-03-12 00:00:00

abstract：:The Rho-family small GTPase Cdc42 localizes at plasma membrane and Golgi complex and aside from protrusion and migration operates in vesicle trafficking, endo- and exocytosis as well as establishment and/or maintenance of cell polarity. The formin family members FMNL2 and -3 are actin assembly factors established to r...

journal_title：Scientific reports

authors： Kage F,Steffen A,Ellinger A,Ranftler C,Gehre C,Brakebusch C,Pavelka M,Stradal T,Rottner K

更新日期：2017-08-29 00:00:00

abstract：:The insect vector borne bacterium Xylella fastidiosa was first detected in olive trees in Southern Italy in 2013, and identified as the main culprit behind the 'olive quick decline syndrome'. Since then, the disease has spread rapidly through Italy's main olive oil producing region. The epidemiology of the outbreak is...

journal_title：Scientific reports

authors： Strona G,Carstens CJ,Beck PS

更新日期：2017-03-06 00:00:00

abstract：:The phase diagrams of continuous binary nanoalloys are important in providing guidance for material designs and industrial applications. However, experimental determination of the nano-phase diagram is scarce since calorimetric measurements remain quite challenging at the nanoscale. Based on the size-dependent cohesiv...

journal_title：Scientific reports

authors： Cui M,Lu H,Jiang H,Cao Z,Meng X

更新日期：2017-02-07 00:00:00

abstract：:Crossmodal studies have reported not only facilitatory but also inhibitory perceptual interactions. For instance, tactile stimulation to the index finger of a hand leads to the degradation of visual discrimination performance (touch-induced visual suppression, TIVS). It has been suggested that the magnitude of TIVS de...

journal_title：Scientific reports

authors： Hidaka S,Suzuishi Y,Ide M,Wada M

更新日期：2018-11-19 00:00:00

abstract：:The Kidney Donor Profile Index (KDPI) was introduced in the United States in 2014 to guide the decision making of clinicians with respect to accepting or declining a donated kidney. To evaluate whether the KDPI can be applied to a European cohort, we retrospectively assessed 580 adult patients who underwent renal tran...

journal_title：Scientific reports

authors： Dahmen M,Becker F,Pavenstädt H,Suwelack B,Schütte-Nütgen K,Reuter S

更新日期：2019-08-02 00:00:00

abstract：:Quantum cryptography is commonly used to generate fresh secure keys with quantum signal transmission for instant use between two parties. However, research shows that the relatively low key generation rate hinders its practical use where a symmetric cryptography component consumes the shared key. That is, the security...

journal_title：Scientific reports

authors： Lai H,Luo MX,Pieprzyk J,Zhang J,Pan L,Li S,Orgun MA

更新日期：2017-04-13 00:00:00

abstract：:We report the temperature dependence of the dielectric function ε = ε1 + iε2 and critical point (CP) energies of biaxial α-SnS in the spectral energy region from 0.74 to 6.42 eV and temperatures from 27 to 350 K using spectroscopic ellipsometry. Bulk SnS was grown by temperature gradient method. Dielectric response fu...

journal_title：Scientific reports

authors： Nguyen HT,Le VL,Nguyen TMH,Kim TJ,Nguyen XA,Kim B,Kim K,Lee W,Cho S,Kim YD

更新日期：2020-10-27 00:00:00

abstract：:COX-2 inhibition may be of benefit in the treatment of tuberculosis (TB) through a number of pathways including efflux pump inhibition (increasing intracellular TB drug levels) and diverse effects on inflammation and the immune response. We investigated celecoxib (a COX-2 inhibitor) alone and with standard anti-tuberc...

journal_title：Scientific reports

authors： Naftalin CM,Verma R,Gurumurthy M,Hee KH,Lu Q,Yeo BCM,Tan KH,Lin W,Yu B,Seng KY,Lee LS,Paton NI

更新日期：2018-09-10 00:00:00

abstract：:The importance of microbial natural products has been widely demonstrated in the search for new antibiotics. However, the functional role of microbial metabolites in nature remains to be deciphered. Several natural products are known to mediate microbial interactions through metabolic exchange. One approach to investi...

journal_title：Scientific reports

authors： Caraballo-Rodríguez AM,Dorrestein PC,Pupo MT

更新日期：2017-07-14 00:00:00

abstract：:Fibrin glue has been used clinically for decades in a wide variety of surgical specialties and is now being investigated as a medium for local, prolonged drug delivery. Effective local delivery of antibacterial substances is important perioperatively in patients with implanted medical devices or postoperatively for de...

journal_title：Scientific reports

authors： Rubalskii E,Ruemke S,Salmoukas C,Aleshkin A,Bochkareva S,Modin E,Mashaqi B,Boyle EC,Boethig D,Rubalsky M,Zulkarneev E,Kuehn C,Haverich A

更新日期：2019-02-14 00:00:00

abstract：:Antiphospholipid syndrome is associated with an increased risk of thrombosis and pregnancy loss. Annexin A5 (Anxa5) is a candidate autoantigen. It is not known, however, whether endogenous Anxa5 prevents foetal loss during normal pregnancy. We found significant reductions in litter size and foetal weight in Anxa5-null...

journal_title：Scientific reports

authors： Ueki H,Mizushina T,Laoharatchatathanin T,Terashima R,Nishimura Y,Rieanrakwong D,Yonezawa T,Kurusu S,Hasegawa Y,Brachvogel B,Pöschl E,Kawaminami M

更新日期：2012-01-01 00:00:00

abstract：:Shoulder apprehension is more complex than a pure mechanical problem of the shoulder, creating a scar at the brain level that prevents the performance of specific movements. Surgery corrects for shoulder instability at the physical level, but a re-dislocation within the first year is rather common. Predicting which pa...

journal_title：Scientific reports

authors： Zanchi D,Cunningham G,Lädermann A,Ozturk M,Hoffmeyer P,Haller S

更新日期：2017-03-29 00:00:00

abstract：:The protein encoded by the TERMINAL FLOWER1 (TFL1) gene maintains indeterminacy in inflorescence meristem to repress flowering, and has undergone multiple duplications. However, basal angiosperms have one copy of a TFL1-like gene, which clusters with eudicot TFL1/CEN paralogs. Functional conservation has been reported...

journal_title：Scientific reports

authors： Gao J,Huang BH,Wan YT,Chang J,Li JQ,Liao PC

更新日期：2017-11-01 00:00:00