A comprehensive study on genome-wide coexpression network of KHDRBS1/Sam68 reveals its cancer and patient-specific association.

abstract：:This paper reports a facile and green method for conversion of graphene oxide (GO) into graphene by low-temperature heating (80 °C) in the presence of a glass wafer. Compared to conventional GO chemical reduction methods, the presented approach is easy-scalable, operationally simple, and based on the use of a non-toxi...

journal_title：Scientific reports

authors： Rabchinskii MK,Dideikin AT,Kirilenko DA,Baidakova MV,Shnitov VV,Roth F,Konyakhin SV,Besedina NA,Pavlov SI,Kuricyn RA,Lebedeva NM,Brunkov PN,Vul' AY

更新日期：2018-09-20 00:00:00

abstract：:Antiretroviral therapy-naive HIV-1 infected infants experience poor viral containment and rapid disease progression compared to adults. Viral factors (e.g. transmitted cytotoxic T- lymphocyte (CTL) escape mutations) or infant factors (e.g. reduced CTL functional capacity) may explain this observation. We assessed CTL ...

journal_title：Scientific reports

authors： Garcia-Knight MA,Slyker J,Payne BL,Pond SL,de Silva TI,Chohan B,Khasimwa B,Mbori-Ngacha D,John-Stewart G,Rowland-Jones SL,Esbjörnsson J

更新日期：2016-07-12 00:00:00

abstract：:Visualization of the surgically operated tissues is vital to improve surgical model animals including mouse. Urological surgeries for urethra include series of fine manipulations to treat the increasing number of birth defects such as hypospadias. Hence visualization of the urethral status is vital. Inappropriate uret...

journal_title：Scientific reports

authors： Hyuga T,Hashimoto D,Matsumaru D,Kumegawa S,Asamura S,Suzuki K,Katayama KI,Nakamura S,Nakai H,Yamada G

更新日期：2020-10-26 00:00:00

abstract：:This study was designed to evaluate the prognostic value of platelet to lymphocyte ratio (PLR) in hepatocellular carcinoma (HCC). A comprehensive literature search for relevant studies was performed in Web of science, Embase and Pubmed. A total of nine studies with 2017 patients were included in this meta-analysis, an...

journal_title：Scientific reports

authors： Ma W,Zhang P,Qi J,Gu L,Zang M,Yao H,Shi X,Wang C,Jiang Y

更新日期：2016-10-14 00:00:00

abstract：:The major components of vitelline membrane (VM) are ovomucin, VM outer (VMO) I and VMO II. At present, the distribution pattern of maternal cells on the VM has not been described in detail. In this study, the existence and distribution characteristics of maternal cells on VM were observed. There were more than 3.2 × 1...

journal_title：Scientific reports

authors： Li Q,Li W,Li X,Liu L,Zhang Y,Guo Y,Chen X,Xu G,Zheng J

更新日期：2017-07-26 00:00:00

abstract：:Studies have demonstrated that inflammatory bowel disease (IBD) patients are at an increased risk of developing anxiety and/or depression. IBD patients with depression/anxiety have higher rates of hospitalization and increased disease severity than those without. So far, there is a paucity of data concerning the impac...

journal_title：Scientific reports

authors： Gao X,Tang Y,Lei N,Luo Y,Chen P,Liang C,Duan S,Zhang Y

更新日期：2021-01-14 00:00:00

abstract：:The secreted Ly-6/uPAR Related Protein-1 (SLURP1) is an immunomodulatory protein that promotes corneal immune- and angiogenic-privilege. Here, we have examined the influence of SLURP1 on neutrophil-vascular endothelial cell interactions using human umbilical vein endothelial cells (HUVEC) and differentiated neutrophil...

journal_title：Scientific reports

authors： Swamynathan S,Tiwari A,Loughner CL,Gnalian J,Alexander N,Jhanji V,Swamynathan SK

更新日期：2019-04-11 00:00:00

abstract：:Living organisms in drying environments build anisotropic structures and exhibit directionality through self-organization of biopolymers. However, the process of macro-scale assembly is still unknown. Here, we introduce a dissipative structure through a non-equilibrium process between hydration and deposition in the d...

journal_title：Scientific reports

authors： Okeyoshi K,Okajima MK,Kaneko T

更新日期：2017-07-21 00:00:00

abstract：:Visual field (VF) testing has usually been performed with the central gaze as a fixed point. Recent publications indicated optic nerve head deformations induced by optic nerve traction force can promote the progression of optic neuropathies, including glaucoma. We generated a new static test protocol that adds 6° addu...

journal_title：Scientific reports

authors： Shoji T,Mine I,Kumagai T,Kosaka A,Yoshikawa Y,Shinoda K

更新日期：2020-12-03 00:00:00

abstract：:To address the limitations of titanium dioxide (TiO2) and expand the applicability of the photocatalytic activity of TiO2,WSe2 and silica, an eco-friendly, self-assembled method for combining a silica precursor with a WSe2-graphene-TiO2 composite with cetyltrimethylammonium bromide (CTAB) as surface active agents is p...

journal_title：Scientific reports

authors： Zhu L,Nguyen DCT,Woo JH,Zhang Q,Cho KY,Oh WC

更新日期：2018-08-24 00:00:00

abstract：:Understanding the neural basis of poor impulse control in Internet addiction (IA) is important for understanding the neurobiological mechanisms of this syndrome. The current study investigated how neuronal pathways implicated in response inhibition were affected in IA using a Go-Stop paradigm and functional magnetic r...

journal_title：Scientific reports

authors： Li B,Friston KJ,Liu J,Liu Y,Zhang G,Cao F,Su L,Yao S,Lu H,Hu D

更新日期：2014-05-22 00:00:00

abstract：:We investigated gender differences in the optic nerve head (ONH) microcirculation status in association with obstructive sleep apnea (OSA) by using laser speckle flowgraphy (LSFG). We evaluated 150 men (60.5 ± 11.0 yrs) and 45 women (63.0 ± 10.6 yrs) who underwent overnight polysomnography. The mean blur rate (MBR), m...

journal_title：Scientific reports

authors： Shiba T,Takahashi M,Matsumoto T,Hori Y

更新日期：2019-12-11 00:00:00

abstract：:A growing body of research suggests that impaired bladder Cajal-like interstitial cells (ICCs) are a important component in the pathogenesis of diabetes-induced bladder dysfunction, although the molecular mechanisms have not been illustrated completely. The purpose of this study was to examine whether the hyperpolariz...

journal_title：Scientific reports

authors： Dong X,Song Q,Zhu J,Zhao J,Liu Q,Zhang T,Long Z,Li J,Wu C,Wang Q,Hu X,Damaser M,Li L

更新日期：2016-04-28 00:00:00

abstract：:Transplantation of stem cell-derived insulin producing cells (IPCs) has been proposed as an alternative to islet transplantation for the treatment of diabetes mellitus. However, current IPC differentiation protocols are focused on generating functional cells from the pluripotent stem cells and tend to rely on multiste...

journal_title：Scientific reports

authors： Oh JE,Choi OK,Park HS,Jung HS,Ryu SJ,Lee YD,Lee SA,Chung SS,Choi EY,Lee DS,Gho YS,Lee H,Park KS

更新日期：2019-03-29 00:00:00

abstract：:The spin-transfer nano-oscillator (STNO) offers the possibility of using the transfer of spin angular momentum via spin-polarized currents to generate microwave signals. However, at present STNO microwave emission mainly relies on both large drive currents and external magnetic fields. These issues hinder the implemen...

journal_title：Scientific reports

authors： Zeng Z,Finocchio G,Zhang B,Khalili Amiri P,Katine JA,Krivorotov IN,Huai Y,Langer J,Azzerboni B,Wang KL,Jiang H

更新日期：2013-01-01 00:00:00

abstract：:In plants and parenchymatous brown algae the body arises through the activity of an apical meristem (a niche of cells or a single cell). The meristem produces lateral organs in specific patterns, referred to as phyllotaxis. In plants, two different control mechanisms have been proposed: one is position-dependent and r...

journal_title：Scientific reports

authors： Linardić M,Braybrook SA

更新日期：2017-10-24 00:00:00

abstract：:Wild and domesticated bee species are exposed to a variety of pesticides which may drive pollinator decline. Due to wild bee sensitivity data shortage, it is unclear if the honey bee Apis mellifera is a suitable surrogate species in the current EU risk assessment scheme. Furthermore, the underlying causes for sensitiv...

journal_title：Scientific reports

authors： Uhl P,Franke LA,Rehberg C,Wollmann C,Stahlschmidt P,Jeker L,Brühl CA

更新日期：2016-09-30 00:00:00

abstract：:Algae-bacteria interaction is one of the main factors underlying the formation of harmful algal blooms (HABs). The aim of this study was to develop a genome-wide high-throughput screening method to identify HAB-influenced specific interactive bacterial metabolites using a comprehensive collection of gene-disrupted E. ...

journal_title：Scientific reports

authors： Heo J,Cho K,Kim U,Cho DH,Ko S,Tran QG,Lee YJ,Ryu CM,Kim HS

更新日期：2020-06-30 00:00:00

abstract：:Synchrotron radiation core-level photoemission spectroscopy, scanning tunneling microscopy (STM), and first-principles calculations have been utilized to explore the growth processes and the atomic structure of the resulting films during the two-step molecular beam epitaxy (MBE) of In and Bi on the Si(111) surface. De...

journal_title：Scientific reports

authors： Lin CY,Hsu CH,Huang YZ,Hsieh SC,Chen HD,Huang L,Huang ZQ,Chuang FC,Lin DS

更新日期：2019-01-24 00:00:00

abstract：:Herein, we propose a new strategy of maskless lithographic approach to fabricate micro/nano-porous structures by phase separation of polystyrene (PS)/Polyethylene glycol (PEG) immiscible polymer blend. Its simple process only involves a spin coating of polymer blend followed by a development with deionized water rinse...

journal_title：Scientific reports

authors： Guo X,Liu L,Zhuang Z,Chen X,Ni M,Li Y,Cui Y,Zhan P,Yuan C,Ge H,Wang Z,Chen Y

更新日期：2015-10-30 00:00:00

abstract：:Acute lymphoblastic leukaemia (ALL) is the most common childhood cancer and has a high survival rate when properly managed. Prognosis is correlated with many factors such as age, gender, white blood cell (WBC) count, CD10, French-American-British (FAB) classification, and many others. Many of these factors are include...

journal_title：Scientific reports

authors： Kakaje A,Alhalabi MM,Ghareeb A,Karam B,Mansour B,Zahra B,Hamdan O

更新日期：2020-04-21 00:00:00

abstract：:Spatially uniform reconstitution of dried reagents is critical to the function of paper microfluidic devices. Advancing fluid fronts in paper microfluidic devices drive (convect) and concentrate rehydrated reagents to the edges, causing steep chemical gradients and imperfect mixing. This largely unsolved problem in pa...

journal_title：Scientific reports

authors： Das D,Dsouza A,Kaur N,Soni S,Toley BJ

更新日期：2019-10-31 00:00:00

abstract：:MircoRNA's (miR) have been recognised as important modulators of gene expression and potential biomarkers. However, they have been rarely investigated in bio fluids apart from blood. We investigated the association of miR-125b and miR-155 with complications of cirrhosis. Ascites was prospectively collected from patien...

journal_title：Scientific reports

authors： Lutz P,M Haimid M,Pohlmann A,Lehmann J,Jansen C,Schierwagen R,Klein S,Strassburg CP,Spengler U,Trebicka J

更新日期：2017-01-11 00:00:00

abstract：:In recent years, there is a growing interest towards the green synthesis of metal nanoparticles, particularly from plants; however, yet no published study on the synthesis of ZnO.NPs using the Deverra tortuosa extract. Through this study, zinc oxide nanoparticles (ZnO.NPs) have been synthesized based on using the envi...

journal_title：Scientific reports

authors： Selim YA,Azb MA,Ragab I,H M Abd El-Azim M

更新日期：2020-02-26 00:00:00

abstract：:Tail-anchored (TA) proteins are post-translationally inserted into membranes. The TRC40 pathway targets TA proteins to the endoplasmic reticulum via a receptor comprised of WRB and CAML. TRC40 pathway clients have been identified using in vitro assays, however, the relevance of the TRC40 pathway in vivo remains unknow...

journal_title：Scientific reports

authors： Rivera-Monroy J,Musiol L,Unthan-Fechner K,Farkas Á,Clancy A,Coy-Vergara J,Weill U,Gockel S,Lin SY,Corey DP,Kohl T,Ströbel P,Schuldiner M,Schwappach B,Vilardi F

更新日期：2016-12-21 00:00:00

abstract：:Src family of kinases (SFKs) has been found to play an important role in the regulation of nociception. However, how each member of this family acts in the central nervous system (CNS) structures involved in the relay and/or modulation of nociceptive signals, and thereby contributes to the formation and maintenance of...

journal_title：Scientific reports

authors： Ma H,Yao C,Ma P,Zhou J,Gong S,Tao J,Yu XM,Jiang X

更新日期：2019-03-07 00:00:00

abstract：:Neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR) and platelet count (PC) were shown to be prognostic in several solid malignancies. We analysed 603 R0 resected patients to assess whether NLR, PLR and PC correlate with other well-known prognostic factors and survival of patients with colorectal ...

journal_title：Scientific reports

authors： Pedrazzani C,Mantovani G,Fernandes E,Bagante F,Luca Salvagno G,Surci N,Campagnaro T,Ruzzenente A,Danese E,Lippi G,Guglielmi A

更新日期：2017-05-04 00:00:00

abstract：:The involvement of brain glycogen in the progress of chronic stress-induced impairment of hippocampal astrocyte structural plasticity and depression-like behavior is yet to be clarified. The present study designed three experiments to determine the role of brain glycogen in the plasticity and behavioral consequences o...

journal_title：Scientific reports

authors： Zhao Y,Zhang Q,Shao X,Ouyang L,Wang X,Zhu K,Chen L

更新日期：2017-02-24 00:00:00

abstract：:Visceral adiposity index (VAI) has been associated with various cardio-metabolic diseases; however, there is limited information about its association with cerebrovascular diseases. In this study, we evaluated the relationship between VAI and silent brain infarct (SBI). We evaluated a consecutive series of healthy vol...

journal_title：Scientific reports

authors： Nam KW,Kwon HM,Jeong HY,Park JH,Kwon H,Jeong SM,Kim HJ

更新日期：2020-10-14 00:00:00

abstract：:Tumorigenesis is driven by genetic alterations that perturb the signaling networks regulating proliferation or cell death. In order to block tumor growth, one has to precisely know how these signaling pathways function and interplay. Here, we identified the transcription factor Ets21C as a pivotal regulator of tumor g...

journal_title：Scientific reports

authors： Toggweiler J,Willecke M,Basler K

更新日期：2016-10-07 00:00:00