Abstract：
:Three H10 subtype avian influenza viruses were isolated from domestic ducks in China, designated as SH602/H10N8, FJ1761/H10N3 and SX3180/H10N7, with an intravenous pathogenicity index (IVPI) of 0.39, 1.60, and 1.27, respectively. These H10 viruses showed a complex pathology pattern in different species, although full genome characterizations of the viruses could not identify any molecular determinant underlying the observed phenotypes. Our findings describe the pathobiology of the three H10 subtype AIVs in chickens, ducks, and mice. FJ1761/H10N3 evolved E627K and Q591K substitutions in the gene encoding the PB2 protein in infected mice with severe lung damage, suggesting that H10 subtype avian influenza viruses are a potential threat to mammals.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Zhang M,Zhang X,Xu K,Teng Q,Liu Q,Li X,Yang J,Xu J,Chen H,Zhang X,Li Zdoi
10.1038/srep34489subject
Has Abstractpub_date
2016-09-28 00:00:00pages
34489issn
2045-2322pii
srep34489journal_volume
6pub_type
杂志文章abstract：:Lipids play an important role in energy storage, membrane structure stabilization and signaling. Parasitoids are excellent models to study lipidomics because a majority of them do not accumulate during their free-living life-stage. Studies on parasitoids have mostly focused on the changes in the lipids and gene transc...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-26139-4
更新日期：2018-05-17 00:00:00
abstract：:During the Final Eneolithic the Corded Ware Complex (CWC) emerges, chiefly identified by its specific burial rites. This complex spanned most of central Europe and exhibits demographic and cultural associations to the Yamnaya culture. To study the genetic structure and kin relations in CWC communities, we sequenced th...
journal_title：Scientific reports
pub_type： 历史文章,杂志文章
doi：10.1038/s41598-020-63138-w
更新日期：2020-04-14 00:00:00
abstract：:Opioids are effective analgesics for the management of moderate to severe cancer pain. Here we show that κ opioid receptor (KOR) agonists act as anti-angiogenic factors in tumors. Treatment with KOR agonists, U50,488H and TRK820, significantly inhibited human umbilical vein endothelial cell (HUVEC) migration and tube ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep03213
更新日期：2013-11-14 00:00:00
abstract：:Tropical deforestation is responsible for around one tenth of total anthropogenic carbon emissions, and tropical protected areas (PAs) that reduce deforestation can therefore play an important role in mitigating climate change and protecting biodiversity and ecosystem services. While the effectiveness of PAs in reduci...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-14467-w
更新日期：2017-10-25 00:00:00
abstract：:The world is experiencing crisis of antibiotic resistance not only in pathogenic but also in commensal bacteria. We determine the prevalence of antibiotic resistance in commensal Escherichia coli in young children in rural setting of central India and search for its correlations with demographic and behavioral factors...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-43227-1
更新日期：2019-04-30 00:00:00
abstract：:The transition to agriculture was a key event in human history. The extent to which this transition is associated with biological changes in different world regions remains debated. Cultural and osteological records in Lower Nubia throughout the Holocene have been interpreted as a result of in situ differentiation or ...
journal_title：Scientific reports
pub_type： 历史文章,杂志文章
doi：10.1038/srep31040
更新日期：2016-08-09 00:00:00
abstract：:Although differentiated thyroid carcinoma (DTC) has a good prognosis and survival rate, long-term medication and recurrence monitoring might be needed. The factors that affect postoperative health-related quality of life (HRQoL) in patients with DTC in different regions remain unclear or conflicting. The purpose of th...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-62731-3
更新日期：2020-04-01 00:00:00
abstract：:Platelet-driven reduction in blood clot volume (clot contraction or retraction) has been implicated to play a role in hemostasis and thrombosis. Although these processes are often linked with inflammation, the role of inflammatory cells in contraction of blood clots and thrombi has not been investigated. The aim of th...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-05601-9
更新日期：2017-07-11 00:00:00
abstract：:We aimed to examine the prospective association between first trimester HbA1c and gestational diabetes (GDM) and explore the utility of HbA1c for prediction of GDM. We used data from a case-control study within the prospective NICHD Fetal Growth Studies-Singleton Cohort (2009-2013), which enrolled 2,802 women at 12 U....
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-30833-8
更新日期：2018-08-16 00:00:00
abstract：:Little information is available regarding the adverse effects of pesticides on natural honey bee populations. This study highlights the detrimental effects of pesticides on honey bee olfaction through behavioural studies, scanning electron microscopic imaging of antennal sensillae and confocal microscopic studies of h...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep12504
更新日期：2015-07-27 00:00:00
abstract：:Staphylococci are common causes of healthcare-associated and community-associated infections. However, limited data are available on the prevalence, phenotypes and molecular characteristics of Staphylococci in metro system around the world. 320 surface samples were collected from the Guangzhou metro system to isolate ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep16087
更新日期：2015-10-29 00:00:00
abstract：:This work focuses on the optimization of heterogeneous Fenton-like removal of organic pollutant (dye) from water using newly developed fibrous catalysts based on a full factorial experimental design. This study aims to approximate the feasibility of heterogeneous Fenton-like removal process and optionally make predict...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-72401-z
更新日期：2020-09-30 00:00:00
abstract：:Long-term supply of synthetic nitrogen (N) has the potential to affect the soil N processes. This study aimed to (i) establish N response curves to find the best balance between inputs and outputs of N over four ratoons; (ii) use 15N-labeled fertilizer to estimate the N recovery efficiency of fertilizer applied in the...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-75971-0
更新日期：2020-11-02 00:00:00
abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper. ...
journal_title：Scientific reports
pub_type： 已发布勘误
doi：10.1038/s41598-018-21594-5
更新日期：2018-03-06 00:00:00
abstract：:Forest fragmentation threatens the ecosystem carbon (C) storage. The distribution patterns of ecosystem C density are poorly documented for fragmented forests of differing patch size. The objectives of this study were to examine C density in these forest ecosystems and the influence of edge effects on C density. Allom...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-13598-4
更新日期：2017-10-13 00:00:00
abstract：:In this study, ITS, ITS2, matK, rbcL and psbA-trnH in Rehmannia were successfully amplified and sequenced, but some ITS sequences need to be proofread according to ITS2 sequences. Compared with rbcL, matK and psbA-trnH, ITS and ITS2 had higher mutation rate and more information sites, and ITS2 had higher interspecific...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-53752-8
更新日期：2019-11-21 00:00:00
abstract：:The lithium-sulfur battery, which offers a high energy density and is environmental friendly, is a promising next generation of rechargeable energy storage system. However, despite these attractive attributes, the commercialization of lithium-sulfur battery is primarily hindered by the parasitic reactions between the ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-11922-6
更新日期：2017-09-12 00:00:00
abstract：:Increased biosynthesis of abscisic acid (ABA) occurs in plants in response to water deficit, which is mediated by changes in the levels of reactive oxygen species such as H2O2. Water deficit and ABA induce expression of some RD22-like proteins. This study aimed to evaluate the effect of water deficit and exogenous ABA...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-08976-x
更新日期：2017-08-18 00:00:00
abstract：:RNA virus-based episomal vector (REVec) is an emerging viral vector system that mediates long-term stable gene expression in variety of cell types in vitro. However, little is known about its tissue tropism and persistence of gene expression in vivo. Here, to evaluate the feasibility of REVec for in vivo gene delivery...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-62630-7
更新日期：2020-04-03 00:00:00
abstract：:We have investigated the paths taken by Budgerigars while flying in a tunnel. The flight trajectories of nine Budgerigars (Melopsittacus undulatus) were reconstructed in 3D from high speed stereo videography of their flights in an obstacle-free tunnel. Individual birds displayed highly idiosyncratic flight trajectorie...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-59013-3
更新日期：2020-02-13 00:00:00
abstract：:Peroxisome proliferator-activated receptors (PPARs) are nuclear hormone receptors that act as ligand-activated transcription factors. PPAR agonists have well-documented anti-inflammatory and neuroprotective roles in the central nervous system. Recent evidence suggests that PPAR agonists are attractive therapeutic agen...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep27618
更新日期：2016-06-10 00:00:00
abstract：:Inositol Requiring Enzyme-1 (IRE1) is the most conserved transducer of the Unfolded Protein Response (UPR), a surveillance mechanism that ensures homeostasis of the endoplasmic reticulum (ER) in eukaryotes. IRE1 activation orchestrates adaptive responses, including lipid anabolism, metabolic reprogramming, increases i...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-16662-1
更新日期：2017-11-28 00:00:00
abstract：:Pancreatic cancer induces a substantial global burden. We examined its global incidence/mortality rates and their correlation with socioeconomic development (Human Development Index [HDI] and Gross Domestic Product [GDP] in 2000 as proxy measures). Data on age-standardized incidence/mortality rates in 2012 were retrie...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-02997-2
更新日期：2017-06-09 00:00:00
abstract：:Here we describe a new instrument (SpiderMass) designed for in vivo and real-time analysis. In this instrument ion production is performed remotely from the MS instrument and the generated ions are transported in real-time to the MS analyzer. Ion production is promoted by Resonant Infrared Laser Ablation (RIR-LA) base...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep25919
更新日期：2016-05-18 00:00:00
abstract：:Organic nanofibers have found various applications in optoelectronic devices. In such devices, exciton diffusion is a major aspect concerning their efficiency. In the case of singlet excitons, Förster transfer is the mechanism responsible for this process. Temperature and morphology are factors known to influence exci...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-32232-5
更新日期：2018-09-19 00:00:00
abstract：:Two embedded sulfur atoms in a novel [2 + 2] Schiff-base macrocyclic dinuclear Zn(II) complex were found to be easily autoxidized to the sulfone units on air exposure, and the resultant sulfone-functionalized macrocyclic complex was obtained by the post-modification strategy exhibiting enhanced antimicrobial activitie...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-15898-1
更新日期：2017-11-21 00:00:00
abstract：:Chronic obstructive pulmonary disease (COPD) patients are at higher risk of developing lung cancer and its metastasis, but no suitable biomarker has been reported for differential diagnosis of these patients. Levels of serum biomarkers (VEGF, IL-8, MMP-9 and MMP-2) were analyzed in these patients, which were compared ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep36065
更新日期：2016-11-04 00:00:00
abstract：:The bronchoscopy, though usually safe, is occasionally associated with complications, such as pneumonia. However, the use of prophylactic antibiotics is not recommended by the guidelines of the British Thoracic Society. Thus far there are few reports of the risk factors for post-bronchoscopy pneumonia; the purpose of ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-76998-z
更新日期：2020-11-17 00:00:00
abstract：:The pace of two-dimensional materials (2DM) research has been greatly accelerated by the ability to identify exfoliated thicknesses down to a monolayer from their optical contrast. Since this process requires time-consuming and error-prone manual assignment to avoid false-positives from image features with similar con...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-23922-1
更新日期：2018-04-23 00:00:00
abstract：:Algorithms in bioinformatics use textual representations of genetic information, sequences of the characters A, T, G and C represented computationally as strings or sub-strings. Signal and related image processing methods offer a rich source of alternative descriptors as they are designed to work in the presence of no...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-38197-9
更新日期：2019-02-15 00:00:00
