Autophagy and mitophagy biomarkers are reduced in sera of patients with Alzheimer's disease and mild cognitive impairment.

abstract：:The development of 2D nanomaterial coatings across metal surfaces is a challenge due to the mismatch between the metal microstructure and the nanoscale materials. The naturally occurring thin oxidative layer present across all metal surfaces, may lead to low adherence and connectivity. In this paper, graphene/titania/...

journal_title：Scientific reports

authors： Yi Z,Merenda A,Kong L,Radenovic A,Majumder M,Dumée LF

更新日期：2018-05-25 00:00:00

abstract：:Luminescent zeolites exchanged with two distinct and interacted emissive ions are vital but less-studied for the potential applications in white light emitting diodes, solar cells, optical codes, biomedicine and so on. Typical transition metal ion Mn2+ and lanthanide ion Yb3+ are adopted as a case study via their char...

journal_title：Scientific reports

authors： Ye S,Sun J,Yi X,Wang Y,Zhang Q

更新日期：2017-04-10 00:00:00

abstract：:Bone homeostasis is maintained by the balance of osteoblasts (OBs) and osteoclasts (OCs). Increased activity of OCs not only contributes to pathological bone resorption, such as osteoporosis and periodontitis, but also is responsible for physiological conditions like orthodontic tooth movement (OTM). However, the deta...

journal_title：Scientific reports

authors： Guo T,Zhang L,Konermann A,Zhou H,Jin F,Liu W

更新日期：2015-01-26 00:00:00

abstract：:Abiotic synthesis of biomolecules is an essential step for the chemical origin of life. Many attempts have succeeded in synthesizing biomolecules, including amino acids and nucleobases (e.g., via spark discharge, impact shock, and hydrothermal heating), from reduced compounds that may have been limited in their availa...

journal_title：Scientific reports

authors： Takeuchi Y,Furukawa Y,Kobayashi T,Sekine T,Terada N,Kakegawa T

更新日期：2020-06-08 00:00:00

abstract：:The Mongol invasion of Eastern Europe, and especially its sudden withdrawal from Hungary in 1242 CE, has generated much speculation and an array of controversial theories. None of them, however, considered multifaceted environmental drivers and the coupled analysis of historical reports and natural archives. Here we i...

journal_title：Scientific reports

authors： Büntgen U,Di Cosmo N

更新日期：2016-05-26 00:00:00

abstract：:Three-dimensionally (3D) porous morphology of nanostructures can effectively improve their electrocatalytic activity and durability for various electrochemical reactions owing to big surface area and interconnected structure. Cyanogel, a jelly-like inorganic polymer, can be used to synthesize various three-dimensional...

journal_title：Scientific reports

authors： Liu X,Xu G,Chen Y,Lu T,Tang Y,Xing W

更新日期：2015-01-05 00:00:00

abstract：:At mid-ocean ridges volcanism generally decreases with spreading rate but surprisingly massive volcanic centres occur at the slowest spreading ridges. These volcanoes can host unexpectedly strong earthquakes and vigorous, explosive submarine eruptions. Our understanding of the geodynamic processes forming these volcan...

journal_title：Scientific reports

authors： Schmid F,Schlindwein V,Koulakov I,Plötz A,Scholz JR

更新日期：2017-02-20 00:00:00

abstract：:Pyrene-conjugated compounds are detected by label-assisted laser desorption/ionization mass spectrometry (LA-LDI MS) without matrixes. We found that 6-amidopyrene derivatives were highly detectable by the LDI MS instrument equipped with a 355 nm laser. In a certain case of a 6-amidopyrene derivative, a molecular ion p...

journal_title：Scientific reports

authors： Yoneda K,Hu Y,Kita M,Kigoshi H

更新日期：2015-12-15 00:00:00

abstract：:Grassland degradation due to overgrazing is common in many areas of the world. This study analyzed the potential of the stable carbon isotope (δ(13)C) value as a structural microcosmic index to monitor processes of grassland degradation. The δ(13)C values of plant leaves, roots and soils in non-grazed (NG) and over-gr...

journal_title：Scientific reports

authors： Yao H,Wilkes A,Zhu G,Zhang H,Liu X,Dan Ding,Zhai X,Tang S,Chen Q,Zhang Y,Huang D,Wang C

更新日期：2016-08-16 00:00:00

abstract：:Cell fate decisions are controlled by the interplay of transcription factors and epigenetic modifiers, which together determine cellular identity. Here we elaborate on the role of miR302 in the regulation of cell plasticity. Overexpression of miR302 effected silencing of the TGFβ type II receptor and facilitated plast...

journal_title：Scientific reports

authors： De Chiara L,Andrews D,Watson A,Oliviero G,Cagney G,Crean J

更新日期：2017-02-14 00:00:00

abstract：:Three dimensional (3D) microvascular imaging of cubic millimeter to centimeter size volumes often requires much time and expensive instruments. By combining optical clearing with a novel scatter-based optical coherence tomography (OCT) contrast agent, we have greatly extended OCT imaging depth in excised tissues while...

journal_title：Scientific reports

authors： Liu Y,Broberg MCG,Watanabe M,Rollins AM,Jenkins MW

更新日期：2019-01-29 00:00:00

abstract：:Type 1 diabetes can be overcome by regulatory T cells (Treg) in NOD mice yet an efficient method to generate and maintain antigen-specific Treg is difficult to come by. Here, we devised a combination therapy of peptide/MHC tetramers and IL-2/anti-IL-2 monoclonal antibody complexes to generate antigen-specific Treg and...

journal_title：Scientific reports

authors： Izquierdo C,Ortiz AZ,Presa M,Malo S,Montoya A,Garabatos N,Mora C,Verdaguer J,Stratmann T

更新日期：2018-05-25 00:00:00

abstract：:Although semantic processing has traditionally been associated with brain responses maximal at 350-400 ms, recent studies reported that words of different semantic types elicit topographically distinct brain responses substantially earlier, at 100-200 ms. These earlier responses have, however, been achieved using insu...

journal_title：Scientific reports

authors： Moseley RL,Pulvermüller F,Shtyrov Y

更新日期：2013-01-01 00:00:00

abstract：:Thermal management and simulation are becoming increasingly important in many areas of engineering applications. There are three cooling routes for thermal management, namely thermal conduction, thermal convection and thermal radiation, among which the first two approaches have been widely studied and applied, while t...

journal_title：Scientific reports

authors： Zhang HH,Sha WEI,Huang ZX,Shi GM

更新日期：2018-02-08 00:00:00

abstract：:The voltage-gated sodium channel isoform NaV1.7 is highly expressed in dorsal root ganglion neurons and is obligatory for nociceptive signal transmission. Genetic gain-of-function and loss-of-function NaV1.7 mutations have been identified in select individuals, and are associated with episodic extreme pain disorders a...

journal_title：Scientific reports

authors： Pajouhesh H,Beckley JT,Delwig A,Hajare HS,Luu G,Monteleone D,Zhou X,Ligutti J,Amagasu S,Moyer BD,Yeomans DC,Du Bois J,Mulcahy JV

更新日期：2020-09-09 00:00:00

abstract：:Male infertility due to spermatogenesis defects affects millions of men worldwide. However, the genetic etiology of the vast majority remains unclear. Here we describe three men with primary infertility due to multiple morphological abnormalities of the sperm flagella (MMAF) from two unrelated Han Chinese families. We...

journal_title：Scientific reports

authors： Tu C,Nie H,Meng L,Yuan S,He W,Luo A,Li H,Li W,Du J,Lu G,Lin G,Tan YQ

更新日期：2019-11-01 00:00:00

abstract：:Demand is increasing for superhydrophobic materials in many applications, such as membrane distillation, separation and special coating technologies. In this study, we report a chemical vapor deposition (CVD) process to fabricate superhydrophobic carbon nanomaterials (CNM) on nickel (Ni)-doped powder activated carbon ...

journal_title：Scientific reports

authors： Aljumaily MM,Alsaadi MA,Das R,Hamid SBA,Hashim NA,AlOmar MK,Alayan HM,Novikov M,Alsalhy QF,Hashim MA

更新日期：2018-02-09 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Fülep C,Kovács I,Kránitz K,Erdei G

更新日期：2019-11-22 00:00:00

abstract：:Three-dimensional ion and particle concentrations under hydrodynamic focusing in a Y-shaped square microchannel are numerically simulated to clarify the decrease of the ion concentration along the flow direction within the focused particle stream. The simulation model is theoretically governed by the laminar flow and ...

journal_title：Scientific reports

authors： Sato N,Kawashima D,Takei M

更新日期：2021-01-28 00:00:00

abstract：:Novelty seeking (NS) is a personality trait reflecting excitement in response to novel stimuli. High NS is usually a predictor of risky behaviour such as drug abuse. However, the relationships between NS and risk-related cognitive processes, including individual risk preference and the brain activation associated with...

journal_title：Scientific reports

authors： Wang Y,Liu Y,Yang L,Gu F,Li X,Zha R,Wei Z,Pei Y,Zhang P,Zhou Y,Zhang X

更新日期：2015-06-11 00:00:00

abstract：:Many studies speak in favor of a rhythmic mode of listening, by which the encoding of acoustic information is structured by rhythmic neural processes at the time scale of about 1 to 4 Hz. Indeed, psychophysical data suggest that humans sample acoustic information in extended soundscapes not uniformly, but weigh the ev...

journal_title：Scientific reports

authors： Kubetschek C,Kayser C

更新日期：2021-01-27 00:00:00

abstract：:Despite recent advances in drug delivery, the targeted treatment of unhealthy cells or tissues continues to remain a priority. In cancer (much like other pathologies), delivery vectors are designed to exploit physical and biological features of unhealthy tissues that are not always homogenous across the disease. In so...

journal_title：Scientific reports

authors： Evangelopoulos M,Yazdi IK,Acciardo S,Palomba R,Giordano F,Pasto A,Sushnitha M,Martinez JO,Basu N,Torres A,Hmaidan S,Parodi A,Tasciotti E

更新日期：2020-01-13 00:00:00

abstract：:The placenta is an essential organ that is formed during pregnancy and its proper development is critical for embryonic survival. While several animal models have been shown to exhibit some of the pathological effects present in human preeclampsia, these models often do not represent the physiological aspects that hav...

journal_title：Scientific reports

authors： Albers RE,Kaufman MR,Natale BV,Keoni C,Kulkarni-Datar K,Min S,Williams CR,Natale DRC,Brown TL

更新日期：2019-02-26 00:00:00

abstract：:Hand, foot, and mouth disease (HFMD), predominantly occurs among infants and children. Previous studies have shown that suitable, stable temperatures favor HFMD virus reproduction; however, temperature fluctuations also affect virus transmission, and there are, so far, no studies concerning the association between suc...

journal_title：Scientific reports

authors： Xu C,Zhang X,Wang L,Zhou Y,Xiao G,Liao J

更新日期：2020-02-13 00:00:00

abstract：:Species-centric approaches to biodiversity in ecological research are limited in their ability to reflect the evolutionary history and functional diversity of community assembly. Recently, the introduction of alternative facets of biodiversity, such as phylogenetic and functional diversity, has shed light on this prob...

journal_title：Scientific reports

authors： Chun JH,Lee CB

更新日期：2018-02-12 00:00:00

abstract：:Turner syndrome (TS) is characterized by the partial or complete loss of one sex chromosome and results in growth failure, gonadal insufficiency and cardiac anomalies. Treatment with growth hormone (GH) during childhood has indisputable benefits when taking into account the low stature of TS women. Medical records and...

journal_title：Scientific reports

authors： Irzyniec T,Jeż W,Lepska K,Maciejewska-Paszek I,Frelich J

更新日期：2019-11-04 00:00:00

abstract：:Direct estimation of Lagrangian turbulence statistics is essential for the proper modeling of dispersion and transport in highly obstructed canopy flows. However, Lagrangian flow measurements demand very high rates of data acquisition, resulting in bottlenecks that prevented the estimation of Lagrangian statistics in ...

journal_title：Scientific reports

authors： Shnapp R,Shapira E,Peri D,Bohbot-Raviv Y,Fattal E,Liberzon A

更新日期：2019-05-15 00:00:00

abstract：:Traumatic brain injury (TBI) causes brain edema that induces increased intracranial pressure and decreased cerebral perfusion. Decompressive craniectomy has been recommended as a surgical procedure for the management of swollen brain and intracranial hypertension. Proper location and size of a decompressive craniectom...

journal_title：Scientific reports

authors： Lambride C,Christodoulou N,Michail A,Vavourakis V,Stylianopoulos T

更新日期：2020-10-29 00:00:00

abstract：:Assembly of metagenomic samples is a very complex process, with algorithms designed to address sequencing platform-specific issues, (read length, data volume, and/or community complexity), while also faced with genomes that differ greatly in nucleotide compositional biases and in abundance. To address these issues, we...

journal_title：Scientific reports

authors： Scholz M,Lo CC,Chain PS

更新日期：2014-10-01 00:00:00

abstract：:Axolotls have the amazing ability to regenerate. When compared to humans, axolotls display a very fast wound closure, no scarring and are capable to replace lost appendages perfectly. Understanding the signaling mechanism leading to this perfect healing is a key step to help develop regenerative treatments for humans....

journal_title：Scientific reports

authors： Sader F,Denis JF,Laref H,Roy S

更新日期：2019-02-04 00:00:00