Recombinant HIV-1 vaccine candidates based on replication-defective flavivirus vector.

abstract：:The identification of the earliest dogs is challenging because of the absence and/or mosaic pattern of morphological diagnostic features in the initial phases of the domestication process. Furthermore, the natural occurrence of some of these characters in Late Pleistocene wolf populations and the time it took from the...

journal_title：Scientific reports

authors： Boschin F,Bernardini F,Pilli E,Vai S,Zanolli C,Tagliacozzo A,Fico R,Fedi M,Corny J,Dreossi D,Lari M,Modi A,Vergata C,Tuniz C,Moroni A,Boscato P,Caramelli D,Ronchitelli A

更新日期：2020-08-07 00:00:00

abstract：:Bacteria belonging to the genus Acinetobacter have become of clinical importance over the last decade due to the development of a multi-resistant phenotype and their ability to survive under multiple environmental conditions. The development of these traits among Acinetobacter strains occurs frequently as a result of ...

journal_title：Scientific reports

authors： Salto IP,Torres Tejerizo G,Wibberg D,Pühler A,Schlüter A,Pistorio M

更新日期：2018-05-17 00:00:00

abstract：:Mustard aphid, also known as turnip aphid (Lipaphis erysimi) is a major insect pest of rapeseed-mustard group of crops. Tremendous economic significance has led to substantial basic research involving gene-expression studies in this insect species. In qRT-PCR analysis of gene-expression, normalization of data against ...

journal_title：Scientific reports

authors： Koramutla MK,Aminedi R,Bhattacharya R

更新日期：2016-05-11 00:00:00

abstract：:We studied scattering and extinction of individual silver nanorods coupled to the J-aggregate form of the cyanine dye TDBC as a function of plasmon--exciton detuning. The measured single particle spectra exhibited a strongly suppressed scattering and extinction rate at wavelengths corresponding to the J-aggregate abso...

journal_title：Scientific reports

authors： Zengin G,Johansson G,Johansson P,Antosiewicz TJ,Käll M,Shegai T

更新日期：2013-10-29 00:00:00

abstract：:HPIVs are serologically and genetically grouped into four species that account for up to 10% of all hospitalizations due to acute respiratory infection in children under the age of five. Genetic and epidemiological data for the four HPIVs derived from two pediatric cohorts in Viet Nam are presented. Respiratory sample...

journal_title：Scientific reports

authors： Linster M,Do LAH,Minh NNQ,Chen Y,Zhe Z,Tuan TA,Tuan HM,Su YCF,van Doorn HR,Moorthy M,Smith GJD

更新日期：2018-05-01 00:00:00

abstract：:Diapause, a programmed developmental arrest, is common in insects, enabling them to survive adverse seasons. It is well established that pupal diapause is regulated by ecdysteroids secreted by the prothoracic glands (PGs), with cessation of ecdysteroid secretion after pupal ecdysis leading to pupal diapause. A major f...

journal_title：Scientific reports

authors： Yamada N,Kataoka H,Mizoguchi A

更新日期：2017-01-31 00:00:00

abstract：:Fluorescent probes that can distinguish different DNA topologies through changes in optical readout are sought after for DNA-based diagnostics. In this work, the 4,4-difluoro-4-bora-3a, 4a-diaza-s-indacene (BODIPY) chromophore attached to cyanophenyl substituents (BODIPY-CN) has been tethered to the 5'-end of the 15-m...

journal_title：Scientific reports

authors： Deore PS,Soldatov DV,Manderville RA

更新日期：2018-11-15 00:00:00

abstract：:Cancer stem-like cells (CSCs) play a key role in maintaining the aggressiveness of hepatocellular carcinoma (HCC), but the cell-biological regulation of CSCs is unclear. In the study, we report that thyroid hormone (TH) promotes cell self-renewal in HCC cells. TH also increases the percentage of CD90 + HCC cells and p...

journal_title：Scientific reports

authors： Wang T,Xia L,Ma S,Qi X,Li Q,Xia Y,Tang X,Cui D,Wang Z,Chi J,Li P,Feng YX,Xia Q,Zhai B

更新日期：2016-05-12 00:00:00

abstract：:Staphylococcus aureus colonizes the skin of atopic dermatitis (AD) individuals, but the impact of its enterotoxins on the chronic activation of CD4+ T cells demands further analysis. We aimed to analyze the CD4+ T cell anergy profile and their phenotypic and functional features through differential expression of cellu...

journal_title：Scientific reports

authors： Orfali RL,Yoshikawa FSY,Oliveira LMDS,Pereira NZ,de Lima JF,Ramos YÁL,Duarte AJDS,Sato MN,Aoki V

更新日期：2019-09-11 00:00:00

abstract：:In our previous study, a liver-targeting peptide CSP I-plus modified recombinant human Endostatin (rEndostatin, endostar) (rES-CSP) was constructed and showed potent antiangiogenic capability and could specifically bind to human hepatocellular carcinoma cells to make a direct inhibition in vitro. In this study, the bi...

journal_title：Scientific reports

authors： Yan M,Dongmei B,Jingjing Z,Xiaobao J,Jie W,Yan W,Jiayong Z

更新日期：2017-10-26 00:00:00

abstract：:The present work assessed the effects of dietary ratios of essential fatty acids, arachidonic (ARA), eicosapentaenoic (EPA) and docosahexaenoic acid (DHA), on liver and intestine oxidative status, intestinal histomorphology and gut microbiota of gilthead sea bream. Four isoproteic and isolipidic plant-based diets were...

journal_title：Scientific reports

authors： Magalhães R,Guerreiro I,Santos RA,Coutinho F,Couto A,Serra CR,Olsen RE,Peres H,Oliva-Teles A

更新日期：2020-08-14 00:00:00

abstract：:Aging is a multifactorial process that results in progressive loss of regenerative capacity and tissue function while simultaneously favoring the development of a large array of age-related diseases. Evidence suggests that the accumulation of senescent cells in tissue promotes both normal and pathological aging. Oxic ...

journal_title：Scientific reports

authors： Ottaviani A,Eid R,Zoccola D,Pousse M,Dubal JM,Barajas E,Jamet K,Lebrigand K,Lapébie P,Baudoin C,Giraud-Panis MJ,Rouan A,Beauchef G,Guéré C,Vié K,Barbry P,Tambutté S,Gilson E,Allemand D

更新日期：2020-11-17 00:00:00

abstract：:Malaria in India, while decreasing, remains a serious public health problem, and the contribution of submicroscopic and asymptomatic infections to its persistence is poorly understood. We conducted community surveys and clinic studies at three sites in India differing in their eco-epidemiologies: Chennai (Tamil Nadu),...

journal_title：Scientific reports

authors： van Eijk AM,Sutton PL,Ramanathapuram L,Sullivan SA,Kanagaraj D,Priya GSL,Ravishankaran S,Asokan A,Sangeetha V,Rao PN,Wassmer SC,Tandel N,Patel A,Desai N,Choubey S,Ali SZ,Barla P,Oraon RR,Mohanty S,Mishra S,Kale S

更新日期：2019-11-19 00:00:00

abstract：:We study the entanglement structure and the topological edge states of the ground state of the spin-1/2 XXZ model with bond alternation. We employ parity-density matrix renormalization group with periodic boundary conditions. The finite-size scaling of Rényi entropies S2 and S∞ are used to construct the phase diagram ...

journal_title：Scientific reports

authors： Tzeng YC,Dai L,Chung MC,Amico L,Kwek LC

更新日期：2016-05-24 00:00:00

abstract：:Xenobiotic resistance is commonly found in species with short generation times such as bacteria, annual plants, and insects. Nevertheless, the fundamental evolutionary principles that govern the spread of resistance alleles hold true for species with longer generation times. One such example could occur with sea lampr...

journal_title：Scientific reports

authors： Christie MR,Sepúlveda MS,Dunlop ES

更新日期：2019-12-03 00:00:00

abstract：:A number of Bruton's tyrosine kinase (BTK) inhibitors are currently in development, yet it has been difficult to visualize BTK expression and pharmacological inhibition in vivo in real time. We synthesized a fluorescent, irreversible BTK binder based on the drug Ibrutinib and characterized its behavior in cells and in...

journal_title：Scientific reports

authors： Turetsky A,Kim E,Kohler RH,Miller MA,Weissleder R

更新日期：2014-04-24 00:00:00

abstract：:Listeria monocytogenes is an intracellular pathogen that causes listeriosis. Due to its intracellular niche, L. monocytogenes has evolved to limit immune recognition and response to infection. Antibodies that are slightly induced by listerial infection are completely unable to protect re-infection of L. monocytogenes....

journal_title：Scientific reports

authors： Asano K,Sashinami H,Osanai A,Hirose S,Ono HK,Narita K,Hu DL,Nakane A

更新日期：2016-12-22 00:00:00

abstract：:In external radiotherapy (RT), the use of flattening filter-free (FFF) radiation beams obtained by removing the flattening filter (FF) in standard linear accelerators is rapidly increasing, and the benefits of clinical use are the issue of research. Advanced treatment techniques have increased the interest in the oper...

journal_title：Scientific reports

authors： Arslan A,Sengul B

更新日期：2020-06-02 00:00:00

abstract：:Seagrass meadows are among the four most productive marine ecosystems in the world. Zostera japonica (Z. japonica) is the most widely distributed species of seagrass in China. However, there is no reference genome or transcriptome available for Z. japonica, impeding progress in functional genomic and molecular ecology...

journal_title：Scientific reports

authors： Chen S,Qiu G,Yang M

更新日期：2019-10-10 00:00:00

abstract：:Determination of the absolute configrations for natural products is one of the most important and challenging tasks, especially when the molecules display high conformational flexibility. In this paper, eight new prenylxanthones, aspergixanthones A-H (1-8), and one known analogue (9), were isolated from the marine-der...

journal_title：Scientific reports

authors： Zhu A,Yang MY,Zhang YH,Shao CL,Wang CY,Hu LD,Cao F,Zhu HJ

更新日期：2018-07-13 00:00:00

abstract：:The empirical research on the public goods game (PGG) indicates that both institutional rewards and institutional punishment can curb free-riding and that the punishment effect is stronger than the reward effect. Self-regarding models that are based on Nash equilibrium (NE) strategies or evolutionary game dynamics cor...

journal_title：Scientific reports

authors： Dong Y,Zhang B,Tao Y

更新日期：2016-06-24 00:00:00

abstract：:Quantum coherence is one of the old but always important concepts in quantum mechanics, and now it has been regarded as a necessary resource for quantum information processing and quantum metrology. However, the question of how to quantify the quantum coherence has just been paid the attention recently (see, e.g., Bau...

journal_title：Scientific reports

authors： Feng XN,Wei LF

更新日期：2017-11-14 00:00:00

abstract：:The relative and combined effects of sleep apnea with diabetes mellitus (DM) on cardiovascular outcomes in patients undergoing coronary artery bypass grafting (CABG) remain unknown. In this secondary analysis of data from the SABOT study, 1007 patients were reclassified into four groups based on their sleep apnea and ...

journal_title：Scientific reports

authors： Aung AT,Koo CY,Tam WW,Chen Z,Kristanto W,Sim HW,Kojodjojo P,Kofidis T,Lee CH

更新日期：2020-12-10 00:00:00

abstract：:We report on the fabrication of spherical Au spheres by pulsed laser treatment using a KrF excimer laser (248 nm, 25 ns) under ambient conditions as a fast and high throughput fabrication technique. The presented experiments were realized using initial Au layers of 100 nm thickness deposited on optically transparent a...

journal_title：Scientific reports

authors： Schmidl G,Jia G,Gawlik A,Kreusch J,Schmidl F,Dellith J,Dathe A,Lin ZH,Huang JS,Plentz J

更新日期：2018-07-26 00:00:00

abstract：:We tested the hypothesis that epigenetic mechanisms in the brain and the immune system are associated with chronic pain. Genome-wide DNA methylation assessed in 9 months post nerve-injury (SNI) and Sham rats, in the prefrontal cortex (PFC) as well as in T cells revealed a vast difference in the DNA methylation landsca...

journal_title：Scientific reports

authors： Massart R,Dymov S,Millecamps M,Suderman M,Gregoire S,Koenigs K,Alvarado S,Tajerian M,Stone LS,Szyf M

更新日期：2016-01-28 00:00:00

abstract：:A comprehensive understanding of the charge/discharge behaviour of high-capacity anode active materials, e.g., Si and Li, is essential for the design and development of next-generation high-performance Li-based batteries. Here, we demonstrate the in situ scanning electron microscopy (in situ SEM) of Si anodes in a con...

journal_title：Scientific reports

authors： Chen CY,Sano T,Tsuda T,Ui K,Oshima Y,Yamagata M,Ishikawa M,Haruta M,Doi T,Inaba M,Kuwabata S

更新日期：2016-10-26 00:00:00

abstract：:The black rhinoceros is again on the verge of extinction due to unsustainable poaching in its native range. Despite a wide historic distribution, the black rhinoceros was traditionally thought of as depauperate in genetic variation, and with very little known about its evolutionary history. This knowledge gap has hamp...

journal_title：Scientific reports

authors： Moodley Y,Russo IM,Dalton DL,Kotzé A,Muya S,Haubensak P,Bálint B,Munimanda GK,Deimel C,Setzer A,Dicks K,Herzig-Straschil B,Kalthoff DC,Siegismund HR,Robovský J,O'Donoghue P,Bruford MW

更新日期：2017-02-08 00:00:00

abstract：:Nicotine is the psychoactive agent involved in nicotine dependence. However, nicotine as a drug, and its effects on human psychology are largely under-investigated in genetic studies. In this study, we recruited 208 current non-smokers to evaluate the effect of nicotine and its relationship to genetic risks to nicotin...

journal_title：Scientific reports

authors： Chen X,Aggen SH,Chen J,Li L,Kendler KS,Blank M,Eissenberg T

更新日期：2015-03-31 00:00:00

abstract：:Food constitutes a fuel of life for human beings. It is therefore of chief importance that their recognition system readily identifies the most relevant properties of food by drawing on semantic memory. One of the most relevant properties to be considered is the level of processing impressed by humans on food. We hypo...

journal_title：Scientific reports

authors： Vignando M,Aiello M,Rinaldi A,Cattarruzza T,Mazzon G,Manganotti P,Eleopra R,Rumiati RI

更新日期：2019-05-15 00:00:00

abstract：:Approximately 300,000 men around the globe self-identify as Ashkenazi Levites, of whom two thirds were previously shown to descend from a single male. The paucity of whole Y-chromosome sequences precluded conclusive identification of this ancestor's age, geographic origin and migration patterns. Here, we report the va...

journal_title：Scientific reports

authors： Behar DM,Saag L,Karmin M,Gover MG,Wexler JD,Sanchez LF,Greenspan E,Kushniarevich A,Davydenko O,Sahakyan H,Yepiskoposyan L,Boattini A,Sarno S,Pagani L,Carmi S,Tzur S,Metspalu E,Bormans C,Skorecki K,Metspalu M,Roots

更新日期：2017-11-02 00:00:00