Abstract:
:Anxiety, depression, and insomnia are highly prevalent among migraineurs and are associated with negative health consequences. Anxiety and depression, however, unlike insomnia, are usually underdiagnosed, due to less self-reporting of these two conditions. The aim of the present study was to evaluate the risk of anxiety and depression in migraineurs with self-reported insomnia, using a general population-based sample. We used data from a nationwide population-based survey on headache and sleep, the Korean Headache-Sleep Study. Of all 2,695 participants, 143 (5.3%), 268 (10.0%), 116 (4.3%), and 290 (10.8%) were classified as having migraine, anxiety, depression, and self-reported insomnia, respectively. The risk of anxiety (odds ratio [OR] = 7.0, 95% confidence interval [CI] = 3.0-16.7) and depression (OR = 3.3, 95% CI = 1.3-8.5) was significantly increased in migraineurs with self-reported insomnia. The sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) for anxiety in migraineurs with self-reported insomnia were 46.5%, 89.0%, 64.5%, and 79.5%, respectively. For depression, the sensitivity, specificity, PPV, and NPV were 41.7%, 82.4%, 32.3%, and 87.5%, respectively. Self-reported insomnia is likely to be comorbid with anxiety and depression in migraineurs and could thus be a useful predictor of anxiety and depression in migraine.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Kim KM,Lee DH,Lee EJ,Roh YH,Kim WJ,Cho SJ,Yang KI,Yun CH,Chu MKdoi
10.1038/s41598-019-55928-8subject
Has Abstractpub_date
2019-12-20 00:00:00pages
19608issue
1issn
2045-2322pii
10.1038/s41598-019-55928-8journal_volume
9pub_type
杂志文章abstract::Adhesion is a significant concern after surgery. Many researchers studied the anti-adhesive effect of statin, of which results were inconsistent. Thus, we purposed to perform a systematic review and meta-analysis to evaluate the effect of statins on postoperative adhesion in an experimental study. A comprehensive sear...
journal_title:Scientific reports
pub_type: 杂志文章,meta分析
doi:10.1038/s41598-018-33145-z
更新日期:2018-10-03 00:00:00
abstract::Insertion sequences (ISs) are ubiquitous and abundant mobile genetic elements in prokaryotic genomes. ISs often encode only one protein, the transposase, which catalyzes their transposition. Recent studies have shown that transposases of many different IS families interact with the β sliding clamp, a DNA replication f...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep13329
更新日期:2015-08-26 00:00:00
abstract::Triple-negative breast cancer (TNBC) is sometimes mistaken for fibroadenoma due to its tendency to show benign morphology on breast ultrasound (US) albeit its aggressive nature. This study aims to develop a radiomics score based on US texture analysis for differential diagnosis between TNBC and fibroadenoma, and to ev...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-31906-4
更新日期:2018-09-10 00:00:00
abstract::Lower cervical dislocation with facet interlocking is one of the most drastic injuries to the cervical spine. The early reduction is thought critical in preventing progressive secondary spinal cord injury. The authors report a new surgical procedure in the management of lower cervical dislocation with facet interlocki...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-37742-w
更新日期:2019-02-04 00:00:00
abstract::This anatomical study sought to investigate the morphological characteristics and biomechanical properties of the oblique popliteal ligament (OPL). Embalmed cadaveric knees were used for the study. The OPL and its surrounding structures were dissected; its morphology was carefully observed, analyzed and measured; its ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep42698
更新日期:2017-02-16 00:00:00
abstract::A potted experiment with Populus × euramericana 'Neva' was carried out to assess whether there are positive effects of magnetic treatment of saline water (MTSW) on nitrogen metabolism under controlled conditions in a greenhouse. Growth properties, nitrogen contents, enzyme activities and metabolite concentrations were...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-45719-6
更新日期:2019-07-11 00:00:00
abstract::Small for gestational age (SGA) is an established risk factor for cerebral palsy (CP) in term infants. However, there is conflicting data on the association between SGA and CP in moderate to late preterm infants. The aim of the article was to explore the relationship between SGA and CP in the moderate to late preterm ...
journal_title:Scientific reports
pub_type: 杂志文章,meta分析,评审
doi:10.1038/srep38853
更新日期:2016-12-13 00:00:00
abstract::The Toarcian Oceanic Anoxic Event (TOAE, Early Jurassic, ~182 Ma ago) was characterised by severe environmental perturbations which led to habitat degradation and extinction of marine species. Warming-induced anoxia is usually identified as main driver, but because marine life was also affected in oxygenated environme...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-61393-5
更新日期:2020-03-13 00:00:00
abstract::VCF2CNA is a tool (Linux commandline or web-interface) for copy-number alteration (CNA) analysis and tumor purity estimation of paired tumor-normal VCF variant file formats. It operates on whole genome and whole exome datasets. To benchmark its performance, we applied it to 46 adult glioblastoma and 146 pediatric neur...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-45938-x
更新日期:2019-07-17 00:00:00
abstract::Cinnabar is a natural mercury sulfide (HgS) mineral of volcanic or hydrothermal origin that is found worldwide. It has been mined prehistorically and historically in China, Japan, Europe, and the Americas to extract metallic mercury (Hg(0)) for use in metallurgy, as a medicinal, a preservative, and as a red pigment fo...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep14679
更新日期:2015-10-01 00:00:00
abstract::Hand, foot, and mouth disease (HFMD) is a common childhood illness caused by enteroviruses. HFMD outbreaks and reported cases have sharply increased in China since 2008. Epidemiological and clinical data of HFMD cases reported in Henan Province were collected from 2008 to 2013. Clinical specimens were obtained from a ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep08904
更新日期:2015-03-10 00:00:00
abstract::E-mail has become the main carrier of spreading malicious software and been widely used for phishing, even high-level persistent threats. The e-mail accounts with high social reputation are primary targets to be attacked and utilized by attackers, suffering a lot of probing attacks for a long time. In this paper, in o...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-63191-5
更新日期:2020-04-29 00:00:00
abstract::Here we report exquisitely distinct material properties of primary vascular smooth muscle (VSM) cells isolated from the thoracic aorta of adult (8 months) vs. aged (30 months) F344XBN rats. Individual VSM cells derived from the aged animals showed a tense internal network of the actin cytoskeleton (CSK), exhibiting in...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-20763-w
更新日期:2018-02-08 00:00:00
abstract::Structural characteristics of the active layers in organic photovoltaic (OPV) devices play a critical role in charge generation, separation and transport. Here we report on morphology and structural control of p-DTS(FBTTh2)2:PC71BM films by means of thermal annealing and 1,8-diiodooctane (DIO) solvent additive process...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep13407
更新日期:2015-08-28 00:00:00
abstract::The mechanical behavior of a single phase (fcc) Al0.3CoCrFeNi high-entropy alloy (HEA) was studied in the low and high strain-rate regimes. The combination of multiple strengthening mechanisms such as solid solution hardening, forest dislocation hardening, as well as mechanical twinning leads to a high work hardening ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep42742
更新日期:2017-02-17 00:00:00
abstract::Single epitaxially-grown semiconductor quantum dots have great potential as single photon sources for photonic quantum technologies, though in practice devices often exhibit nonideal behavior. Here, we demonstrate that amplitude modulation can improve the performance of quantum-dot-based sources. Starting with a brigh...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep01397
更新日期:2013-01-01 00:00:00
abstract::Silver nanorod arrays prepared by oblique angle deposition (AgOADs) represent versatile, simple and inexpensive substrates for high sensitivity surface enhanced Raman scattering (SERS) applications. Their anisotropic nature suggests that their optical responses such as the SERS signal, the depolarization ratio, reflec...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-04565-0
更新日期:2017-06-27 00:00:00
abstract::This article reports preparation of a crosslinked polydimethylsiloxane (PDMS) network via dynamic transesterification reaction between PDMS-diglycidyl ether and pripol 1017 with Zn(OAc)2 as the catalyst. The thermal dynamic nature of the network was investigated by the creep-recovery and stress-relaxation tests. The s...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-11485-6
更新日期:2017-09-19 00:00:00
abstract::Recent studies have shown that L-proline is a natural osmoprotectant and an antioxidant to protect cells from injuries such as that caused by freezing and thawing in many species including plant, ram sperm and human endothelial cells. Nevertheless, this nontoxic cryoprotectant has not yet been applied to mammalian ooc...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep26326
更新日期:2016-07-14 00:00:00
abstract::We investigated the effect of a new Rho kinase inhibitor, SB772077B (SB77) on aqueous outflow facility (OF) in human eyes using human organ-cultured anterior segment (HOCAS). IOP was monitored for 24 h post-treatment with either SB77 (0.1/10/50 µM) or vehicle after a stable baseline pressure. The hydrodynamic pattern ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-33932-8
更新日期:2018-10-19 00:00:00
abstract::Despite the efficacy of synthetic fungicides in controlling postharvest diseases, public concerns regarding chemical residues in food and an increase in drug-resistant strains of pathogens have led to a need for new agents to control postharvest diseases. The current study was performed to find control agents of micro...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-49779-6
更新日期:2019-09-19 00:00:00
abstract::Understanding the processes that shaped contemporary pathogen populations in agricultural landscapes is quite important to define appropriate management strategies and to support crop improvement efforts. Here, we took advantage of an historical record to examine the adaptation pathway of the rice pathogen Xanthomonas...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep34137
更新日期:2016-09-26 00:00:00
abstract::Conventional myeloablative conditioning (MAC) regimens often cause severe regimen-related toxicity (RRT). Furthermore, many patients suffer from poor quality of life in accordance with the increase in long-term survivors. We therefore devised a reduced-toxicity myeloablative conditioning (RTMAC) regimen consisting of ...
journal_title:Scientific reports
pub_type: 临床试验,杂志文章
doi:10.1038/srep06942
更新日期:2014-11-06 00:00:00
abstract::Platinum resistance is one of the most challenging problems in ovarian cancer treatment. High-throughput functional siRNA screening identified tyrosine kinase with immunoglobulin-like and EGF-like domains 1 (TIE-1) as a gene that confers cells resistant to cisplatin. Conversely enforced over-expression of TIE-1 was va...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-31069-2
更新日期:2018-09-04 00:00:00
abstract::Rheumatoid arthritis (RA) is an autoimmune disease characterized by progressive immune-mediated joint deterioration. Current treatments are not antigen specific and are associated with various adverse. We have previously demonstrated that tolerogenic dendritic cells (Tol-DC) are potent antigen-specific immune regulato...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep43188
更新日期:2017-02-23 00:00:00
abstract::High sensitivity magnetoelectric sensors with their electromechanical resonance frequencies < 200 kHz have been recently demonstrated using magnetostrictive/piezoelectric magnetoelectric heterostructures. In this work, we demonstrate a novel magnetoelectric nano-electromechanical systems (NEMS) resonator with an elect...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep01985
更新日期:2013-01-01 00:00:00
abstract::Analysing the link between terrestrial ecosystem productivity (i.e., Net Primary Productivity: NPP) and extreme climate conditions is vital in the context of increasing threats due to climate change. To reveal the impact of changing extreme conditions on NPP, a copula-based probabilistic model was developed, and the s...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-55067-0
更新日期:2019-12-12 00:00:00
abstract::Determining the core structure of complex network systems allows us to simplify them. Using h-bridge and h-strength measurements in a weighted network, we extract the h-backbone core structure. We find that focusing on the h-backbone in a network allows greater simplification because it has fewer edges and thus fewer ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-32430-1
更新日期:2018-09-25 00:00:00
abstract::Doxorubicin (Dox) is a highly effective anticancer drug but cause acute ventricular dysfunction, and also induce late-onset cardiomyopathy and heart failure. Despite extensive studies, the pathogenic sequelae leading to the progression of Dox-associated cardiomyopathy remains unknown. We assessed temporal changes in a...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-37862-3
更新日期:2019-02-14 00:00:00
abstract::Ocean warming increasingly endangers the fitness of marine invertebrates. Transgenerational effects (TE) potentially mitigate the impacts of environmental stress on the embryos of marine invertebrates. The molecular mechanisms, however, remain largely unknown. Using high-throughput RNA sequencing technology, we invest...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-64872-x
更新日期:2020-05-13 00:00:00