A rotary plasmonic nanoclock.

abstract：:Hidden hearing loss (HHL) is a recently described auditory neuropathy believed to contribute to speech discrimination and intelligibility deficits in people with normal audiological tests. Animals and humans with HHL have normal auditory thresholds but defective cochlear neurotransmission, that is, reduced suprathresh...

journal_title：Nature communications

authors： Wan G,Corfas G

更新日期：2017-02-17 00:00:00

abstract：:Strategies to harness photosynthesis from living organisms to generate electrical power have long been considered, yet efficiency remains low. Here, we aimed to reroute photosynthetic electron flow in photosynthetic organisms without compromising their phototrophic properties. We show that 2,6-dimethyl-p-benzoquinone ...

journal_title：Nature communications

authors： Fu HY,Picot D,Choquet Y,Longatte G,Sayegh A,Delacotte J,Guille-Collignon M,Lemaître F,Rappaport F,Wollman FA

更新日期：2017-05-03 00:00:00

abstract：:As academic careers become more competitive, junior scientists need to understand the value that mentorship brings to their success in academia. Previous research has found that, unsurprisingly, successful mentors tend to train successful students. But what characteristics of this relationship predict success, and how...

journal_title：Nature communications

authors： Liénard JF,Achakulvisut T,Acuna DE,David SV

更新日期：2018-11-27 00:00:00

abstract：:Membranes with nano-apertures are versatile templates that possess a wide range of electronic, optical and biomedical applications. However, such membranes have been limited to silicon-based inorganic materials to utilize standard semiconductor processes. Here we report a new type of flexible and free-standing polymer...

journal_title：Nature communications

authors： Cho H,Kim J,Park H,Won Bang J,Seop Hyun M,Bae Y,Ha L,Yoon Kim D,Min Kang S,Jung Park T,Seo S,Choi M,Suh KY

更新日期：2014-01-01 00:00:00

abstract：:Loss of seed dispersal is a key agronomical trait targeted by ancient human selection and has been regarded as a milestone of crop domestication. In this study, in the legume crop soybean Glycine max (L.) Merr. which provides vegetable oils and proteins for humans, we show that the key cellular feature of the shatteri...

journal_title：Nature communications

authors： Dong Y,Yang X,Liu J,Wang BH,Liu BL,Wang YZ

更新日期：2014-01-01 00:00:00

abstract：:Microbial communities mediating anaerobic ammonium oxidation (anammox) represent one of the most energy-efficient environmental biotechnologies for nitrogen removal from wastewater. However, little is known about the functional role heterotrophic bacteria play in anammox granules. Here, we use genome-centric metagenom...

journal_title：Nature communications

authors： Lawson CE,Wu S,Bhattacharjee AS,Hamilton JJ,McMahon KD,Goel R,Noguera DR

更新日期：2017-05-31 00:00:00

abstract：:The performance of conjugated polymer devices is largely dictated by charge transport processes. However, it is difficult to obtain a clear relationship between conjugated polymer structures and charge transport properties, due to the complexity of the structure and the dispersive nature of charge transport in conjuga...

journal_title：Nature communications

authors： Jiang Y,McNeill J

更新日期：2018-10-17 00:00:00

abstract：:To colonise their host, pathogens must counter local environmental and immunological challenges. Here, we reveal that the fungal pathogen Candida albicans exploits diverse host-associated signals to promote immune evasion by masking of a major pathogen-associated molecular pattern (PAMP), β-glucan. Certain nutrients, ...

journal_title：Nature communications

authors： Pradhan A,Avelar GM,Bain JM,Childers D,Pelletier C,Larcombe DE,Shekhova E,Netea MG,Brown GD,Erwig L,Gow NAR,Brown AJP

更新日期：2019-11-22 00:00:00

abstract：:Complex materials often exhibit a hierarchical structure with an intriguing mechanism responsible for the 'propagation' of order from the molecular to the nano- or micro-scale level. In particular, the chirality of biological molecules such as nucleic acids and amino acids is responsible for the helical structure of D...

journal_title：Nature communications

authors： Salamończyk M,Vaupotič N,Pociecha D,Walker R,Storey JMD,Imrie CT,Wang C,Zhu C,Gorecka E

更新日期：2019-04-23 00:00:00

abstract：:The original version of this Article contained errors in Figures 1 and 3. In Fig. 1b, the label 'IP-PBP3' above the second of the three blots incorrectly read 'IP-PBP1B'. In Fig. 3b, the label 'PBP1B' under the first bar of each chart incorrectly read 'PBP1A'. These errors have been corrected in both the PDF and HTML ...

journal_title：Nature communications

authors： Pazos M,Peters K,Casanova M,Palacios P,VanNieuwenhze M,Breukink E,Vicente M,Vollmer W

更新日期：2019-01-30 00:00:00

abstract：:Health risk factors such as body mass index (BMI) and serum cholesterol are associated with many common diseases. It often remains unclear whether the risk factors are cause or consequence of disease, or whether the associations are the result of confounding. We develop and apply a method (called GSMR) that performs a...

journal_title：Nature communications

authors： Zhu Z,Zheng Z,Zhang F,Wu Y,Trzaskowski M,Maier R,Robinson MR,McGrath JJ,Visscher PM,Wray NR,Yang J

更新日期：2018-01-15 00:00:00

abstract：:Soil surface temperature, an important driver of terrestrial biogeochemical processes, depends strongly on soil albedo, which can be significantly modified by factors such as plant cover. In sparsely vegetated lands, the soil surface can be colonized by photosynthetic microbes that build biocrust communities. Here we ...

journal_title：Nature communications

authors： Couradeau E,Karaoz U,Lim HC,Nunes da Rocha U,Northen T,Brodie E,Garcia-Pichel F

更新日期：2016-01-20 00:00:00

abstract：:Protein tyrosine O-sulfation (PTS) plays a crucial role in extracellular biomolecular interactions that dictate various cellular processes. It also involves in the development of many human diseases. Regardless of recent progress, our current understanding of PTS is still in its infancy. To promote and facilitate rele...

journal_title：Nature communications

authors： He X,Chen Y,Beltran DG,Kelly M,Ma B,Lawrie J,Wang F,Dodds E,Zhang L,Guo J,Niu W

更新日期：2020-09-24 00:00:00

abstract：:Gfi1b is a transcriptional repressor expressed in hematopoietic stem cells (HSCs) and megakaryocytes (MKs). Gfi1b deficiency leads to expansion of both cell types and abrogates the ability of MKs to respond to integrin. Here we show that Gfi1b forms complexes with β-catenin, its co-factors Pontin52, CHD8, TLE3 and CtB...

journal_title：Nature communications

authors： Shooshtarizadeh P,Helness A,Vadnais C,Brouwer N,Beauchemin H,Chen R,Bagci H,Staal FJT,Coté JF,Möröy T

更新日期：2019-03-20 00:00:00

abstract：:Some two-dimensional liquid systems are theoretically predicted to have an anomalous phase transition due to unique intermolecular interactions, for example the first-order transition between two-dimensional high-density water and low-density amorphous ice. However, it has never been experimentally observed, to the be...

journal_title：Nature communications

authors： Li W,Kong L,Feng B,Fu H,Li H,Zeng XC,Wu K,Chen L

更新日期：2018-01-15 00:00:00

abstract：:Methyl-specific isotope labeling is a powerful tool to study the structure, dynamics and interactions of large proteins and protein complexes by solution-state NMR. However, widespread applications of this methodology have been limited by challenges in obtaining confident resonance assignments. Here, we present Methyl...

journal_title：Nature communications

authors： Nerli S,De Paula VS,McShan AC,Sgourakis NG

更新日期：2021-01-29 00:00:00

abstract：:In nature, individual cells contain multiple isolated compartments in which cascade enzymatic reactions occur to form essential biological products with high efficiency. Here, we report a cell-inspired design of functional hydrogel particles with multiple compartments, in which different enzymes are spatially immobili...

journal_title：Nature communications

authors： Tan H,Guo S,Dinh ND,Luo R,Jin L,Chen CH

更新日期：2017-09-22 00:00:00

abstract：:Locusts are one of the world's most destructive agricultural pests and represent a useful model system in entomology. Here we present a draft 6.5 Gb genome sequence of Locusta migratoria, which is the largest animal genome sequenced so far. Our findings indicate that the large genome size of L. migratoria is likely to...

journal_title：Nature communications

authors： Wang X,Fang X,Yang P,Jiang X,Jiang F,Zhao D,Li B,Cui F,Wei J,Ma C,Wang Y,He J,Luo Y,Wang Z,Guo X,Guo W,Wang X,Zhang Y,Yang M,Hao S,Chen B,Ma Z,Yu D,Xiong Z,Zhu Y,Fan D,Han L,Wang B,Chen Y,Wang J

更新日期：2014-01-01 00:00:00

abstract：:Animals promote their survival by avoiding rapidly approaching objects that indicate threats. In mice, looming-evoked defensive responses are triggered by the superior colliculus (SC) which receives direct retinal inputs. However, the specific neural circuits that begin in the retina and mediate this important behavio...

journal_title：Nature communications

authors： Huang L,Yuan T,Tan M,Xi Y,Hu Y,Tao Q,Zhao Z,Zheng J,Han Y,Xu F,Luo M,Sollars PJ,Pu M,Pickard GE,So KF,Ren C

更新日期：2017-03-31 00:00:00

abstract：:Memory metamaterials are artificial media that sustain transformed electromagnetic properties without persistent external stimuli. Previous memory metamaterials were realized with phase-change materials, such as vanadium dioxide or chalcogenide glasses, which exhibit memory behaviour with respect to electrically/optic...

journal_title：Nature communications

authors： Kim WY,Kim HD,Kim TT,Park HS,Lee K,Choi HJ,Lee SH,Son J,Park N,Min B

更新日期：2016-01-27 00:00:00

abstract：:Oocyte-specific miRNA function remains unclear in mice and worms because loss of Dgcr8 and Dicer from mouse and worm oocytes, respectively, does not yield oogenic defects. These data lead to several models: (a) miRNAs are not generated in oocytes; (b) miRNAs are generated but do not perform an oogenic function; (c) fu...

journal_title：Nature communications

authors： Minogue AL,Tackett MR,Atabakhsh E,Tejada G,Arur S

更新日期：2018-12-14 00:00:00

abstract：:The application of nanoparticle drug formulations, such as nanoliposomal doxorubicin (Doxil), is increasingly integrated in clinical cancer care. Despite nanomedicine's remarkable potential and growth over the last three decades, its clinical benefits for cancer patients vary. Here we report a non-invasive quantitativ...

journal_title：Nature communications

authors： Pérez-Medina C,Abdel-Atti D,Tang J,Zhao Y,Fayad ZA,Lewis JS,Mulder WJM,Reiner T

更新日期：2016-06-20 00:00:00

abstract：:Circular RNAs are non-coding RNAs, and are enriched in the CNS. Dorsal horn neurons of the spinal cord contribute to pain-like hypersensitivity after nerve injury in rodents. Here we show that spinal nerve ligation is associated with an increase in expression of circAnks1a in dorsal horn neurons, in both the cytoplasm...

journal_title：Nature communications

authors： Zhang SB,Lin SY,Liu M,Liu CC,Ding HH,Sun Y,Ma C,Guo RX,Lv YY,Wu SL,Xu T,Xin WJ

更新日期：2019-09-11 00:00:00

abstract：:The role of microglia in spinal cord injury (SCI) remains poorly understood and is often confused with the response of macrophages. Here, we use specific transgenic mouse lines and depleting agents to understand the response of microglia after SCI. We find that microglia are highly dynamic and proliferate extensively ...

journal_title：Nature communications

authors： Bellver-Landete V,Bretheau F,Mailhot B,Vallières N,Lessard M,Janelle ME,Vernoux N,Tremblay MÈ,Fuehrmann T,Shoichet MS,Lacroix S

更新日期：2019-01-31 00:00:00

abstract：:Individual cells in clonal populations often respond differently to environmental changes; for binary phenotypes, such as cell death, this can be measured as a fractional response. These types of responses have been attributed to cell-intrinsic stochastic processes and variable abundances of biochemical constituents, ...

journal_title：Nature communications

authors： Santos LC,Vogel R,Chipuk JE,Birtwistle MR,Stolovitzky G,Meyer P

更新日期：2019-03-21 00:00:00

abstract：:Mutant Huntingtin (mtHtt) causes neurodegeneration in Huntington's disease (HD) by evoking defects in the mitochondria, but the underlying mechanisms remains elusive. Our proteomic analysis identifies valosin-containing protein (VCP) as an mtHtt-binding protein on the mitochondria. Here we show that VCP is selectively...

journal_title：Nature communications

authors： Guo X,Sun X,Hu D,Wang YJ,Fujioka H,Vyas R,Chakrapani S,Joshi AU,Luo Y,Mochly-Rosen D,Qi X

更新日期：2016-08-26 00:00:00

abstract：:Planar neural networks and interfaces serve as versatile in vitro models of central nervous system physiology, but adaptations of related methods to three dimensions (3D) have met with limited success. Here, we demonstrate for the first time volumetric functional imaging in a bioengineered neural tissue growing in a t...

journal_title：Nature communications

authors： Dana H,Marom A,Paluch S,Dvorkin R,Brosh I,Shoham S

更新日期：2014-06-05 00:00:00

abstract：:Anthropogenic mercury (Hg(0)) emissions oxidize to gaseous Hg(II) compounds, before deposition to Earth surface ecosystems. Atmospheric reduction of Hg(II) competes with deposition, thereby modifying the magnitude and pattern of Hg deposition. Global Hg models have postulated that Hg(II) reduction in the atmosphere oc...

journal_title：Nature communications

authors： Saiz-Lopez A,Sitkiewicz SP,Roca-Sanjuán D,Oliva-Enrich JM,Dávalos JZ,Notario R,Jiskra M,Xu Y,Wang F,Thackray CP,Sunderland EM,Jacob DJ,Travnikov O,Cuevas CA,Acuña AU,Rivero D,Plane JMC,Kinnison DE,Sonke JE

更新日期：2018-11-15 00:00:00

abstract：:Micro-optics are widely used in numerous applications, such as beam shaping, collimation, focusing and imaging. We use femtosecond 3D printing to manufacture free-form micro-optical elements. Our method gives sub-micrometre accuracy so that direct manufacturing even on single-mode fibres is possible. We demonstrate th...

journal_title：Nature communications

authors： Gissibl T,Thiele S,Herkommer A,Giessen H

更新日期：2016-06-24 00:00:00

abstract：:X-chromosome inactivation (XCI), i.e., the inactivation of one of the female X chromosomes, restores equal expression of X-chromosomal genes between females and males. However, ~10% of genes show variable degrees of escape from XCI between females, although little is known about the causes of variable XCI. Using a dis...

journal_title：Nature communications

authors： Luijk R,Wu H,Ward-Caviness CK,Hannon E,Carnero-Montoro E,Min JL,Mandaviya P,Müller-Nurasyid M,Mei H,van der Maarel SM,BIOS Consortium.,Relton C,Mill J,Waldenberger M,Bell JT,Jansen R,Zhernakova A,Franke L,'t Hoen PAC

更新日期：2018-09-14 00:00:00