Natural products, extracts and formulations comprehensive therapy for the improvement of motor function in alcoholic liver disease.

Abstract:

:Alcoholic liver disease (ALD) is a major cause of chronic liver disease worldwide that afflicts human health. With the in-depth study of the disease, its pathogenesis has gradually become clear. Although great breakthroughs have been made in the research of ALD, the research and development of drugs related to ALD has lagged behind seriously. However, natural products have always inspired the development of drugs. Meanwhile, there is evidence that some natural products can also play a certain role in the treatment of ALD. Thus, we reviewed the natural products, extracts and formulations with potential anti-ALD activities by consulting the relevant data in the databases of PubMed, Web of Science and CNKI databases, in order to elucidate the regulated mechanism of these natural products. Sum up, the insights provided in present review will be needed for further exploration of botanical drugs in the development of ALD therapy.

journal_name

Pharmacol Res

journal_title

Pharmacological research

authors

Hu S,Li SW,Yan Q,Hu XP,Li LY,Zhou H,Pan LX,Li J,Shen CP,Xu T

doi

10.1016/j.phrs.2019.104501

subject

Has Abstract

pub_date

2019-12-01 00:00:00

pages

104501

eissn

1043-6618

issn

1096-1186

pii

S1043-6618(19)31153-3

journal_volume

150

pub_type

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