Policy perspectives on alternative models for pharmaceutical rebates: a report from the Institute for Clinical and Economic Review Policy Summit.

abstract：:Translation of medical evidence into practice has not kept pace with the growth of medical technology and knowledge. We present three case studies--statins, drug eluting stents and bone marrow transplantation for breast cancer--to propose a framework for describing five factors that may influence the rate of adoption....

journal_title：Journal of comparative effectiveness research

authors： Dubois RW,Lauer M,Perfetto E

更新日期：2013-07-01 00:00:00

abstract：:AIMS: Stakeholder engagement is fundamental to comparative effectiveness research (CER), but lacks consistent terminology. This paper aims to define stakeholder engagement and present a conceptual model for involving stakeholders in CER. MATERIALS #ENTITYSTARTX00026; METHODS: The definitions and model were developed f...

journal_title：Journal of comparative effectiveness research

authors： Deverka PA,Lavallee DC,Desai PJ,Esmail LC,Ramsey SD,Veenstra DL,Tunis SR

更新日期：2012-03-01 00:00:00

abstract：AIM:Explore perspectives of adolescent and young adult (AYA) and parent stakeholders regarding their engagement in comparative effectiveness research (CER) evaluating cholesterol screening and treatment strategies for 17-21 year olds. METHODS:All nine AYAs and parent stakeholders participating in a 20-member panel of ...

journal_title：Journal of comparative effectiveness research

authors： Saunders T,Mackie TI,Shah S,Gooding H,de Ferranti SD,Leslie LK

更新日期：2016-08-01 00:00:00

abstract：AIM:Compare the safety and efficacy of intermittent fenofibrate versus simvastatin in chronic hemodialysis patients. PATIENTS & METHODS:Sixty patients received either fenofibrate 100 mg or simvastatin 20 mg after their dialysis session (parallel study). The safety and efficacy of drugs on lipid profile, oxidized low-d...

journal_title：Journal of comparative effectiveness research

authors： Abdel Magid AM,Abbassi MM,Iskander EEM,Mohamady O,Farid SF

更新日期：2017-07-01 00:00:00

abstract：:Aim: To compare secukinumab with infliximab in biologic-naive patients with psoriatic arthritis using matching-adjusted indirect comparison. Patients & methods: Individual patient baseline data for secukinumab were matched to published aggregate data for infliximab by key baseline characteristics, with matching weight...

journal_title：Journal of comparative effectiveness research

authors： Strand V,McInnes I,Mease P,Nash P,Thom H,Kalyvas C,Hunger M,Gandhi K,Pricop L,Jugl S,Choy E

更新日期：2019-05-01 00:00:00

abstract：AIM:We conducted a meta-analysis to compare the efficacy and safety of oral and intravenous applications of tranexamic acid (TXA) in total hip arthroplasty (THA). MATERIALS & METHODS:Electronic databases, including PubMed, Cochrane CENTRAL, ScienceDirect and Embase, were searched to identify the studies comparing the ...

journal_title：Journal of comparative effectiveness research

authors： Wang L,Cao JG,Liu J

更新日期：2019-04-01 00:00:00

abstract：AIM:Reducing the fluctuation of blood pressure has recently been recognized as a potential target for improving management of hypertension to prevent cardiovascular events, particularly for strokes. Some randomized controlled trials demonstrated that amlodipine can effectively reduce blood pressure as a well-establishe...

journal_title：Journal of comparative effectiveness research

authors： Zhang L,Yang J,Li L,Liu D,Xie X,Dong P,Lin Y

更新日期：2018-07-01 00:00:00

abstract：AIM:Quantify hematopoietic stem cell transplantation (HSCT) costs in German patients with acute lymphoblastic leukemia (ALL), diffuse large B-cell lymphoma (DLBCL) and follicular lymphoma (FL). METHODS:The primary outcome was direct and indirect costs in patients with ALL/DLBCL/FL who received HSCT between 2010 and 20...

journal_title：Journal of comparative effectiveness research

authors： Mayerhoff L,Lehne M,Hickstein L,Salimullah T,Prieur S,Thomas SK,Zhang J

更新日期：2019-01-01 00:00:00

abstract：AIMS:The potential of dedicated Breast-CT is evaluated by simulating its impact onto the performance of the German breast cancer screening program. Attendance rates, cancer detection and economic implications are quantified. METHODS:Based on a prospective health technology assessment approach, we simulated screening i...

journal_title：Journal of comparative effectiveness research

authors： Ruile G,Djanatliev A,Kriza C,Meier F,Leb I,Kalender WA,Kolominsky-Rabas PL,National Leading-Edge Cluster Medical Technologies ‘Medical Valley EMN’.

更新日期：2015-11-01 00:00:00

abstract：AIM:Details of data quality and how quality issues were solved have not been reported in published comparative effectiveness studies using electronic health record data. METHODS:We developed a conceptual framework of data quality assessment and preprocessing and apply it to a study comparing angiotensin-converting enz...

journal_title：Journal of comparative effectiveness research

authors： Huang Y,Voorham J,Haaijer-Ruskamp FM

更新日期：2016-07-01 00:00:00

abstract：:Aim: Increasing use of selective serotonin-reuptake inhibitors (SSRIs) in Scotland, coupled with safety concerns with some SSRIs, and the increasing availability of generic SSRIs, have resulted in multiple initiatives to improve the quality and efficiency of their prescribing in Scotland. Our aim is to assess their in...

journal_title：Journal of comparative effectiveness research

authors： Godman B,Kurdi A,McCabe H,Johnson CF,Barbui C,MacBride-Stewart S,Hurding S,Leporowski A,Bennie M,Morton A

更新日期：2019-05-01 00:00:00

abstract：:Since 2010, four oral anticoagulants have been approved for marketing in addition to warfarin for treatment of thromboembolic disease. Limited head-to-head data exist comparing these treatments, leaving patients and clinicians with little guidance for selecting a strategy that balances recurrence reduction with bleedi...

journal_title：Journal of comparative effectiveness research

authors： Krumme AA,Pawar A,Schneeweiss S,Glynn RJ,Choudhry NK,Kulldorff M,Ortiz AS,Avorn J,Gagne JJ

更新日期：2018-01-01 00:00:00

abstract：AIM:GNE myopathy, a rare, severe, progressive myopathy, presents with lower extremity distal muscle weakness. The GNE myopathy functional activity scale (GNEM-FAS) evaluates the impact of GNE myopathy on functioning in adults. This paper presents the psychometric validation of the GNEM-FAS. PATIENTS & METHODS:Validati...

journal_title：Journal of comparative effectiveness research

authors： Mayhew J,Bonner N,Arbuckle R,Turnbull A,Bowden A,Skrinar A

更新日期：2018-04-01 00:00:00

abstract：:Aim: Indirect treatment comparisons are used when no direct comparison is available. Comparison networks should satisfy the transitivity assumption, that is, equal likelihood of treatment assignment for a given patient based on comparability of studies. Materials & methods: Seven criteria were evaluated across 18 rand...

journal_title：Journal of comparative effectiveness research

authors： Tremblay G,Westley T,Forsythe A,Pelletier C,Briggs A

更新日期：2019-11-01 00:00:00

abstract：AIM:The incremental cost of peripheral orbital atherectomy system (OAS) plus balloon angioplasty (BA) versus BA-only for critical limb ischemia was estimated. MATERIALS & METHODS:A deterministic simulation model used clinical and healthcare utilization data from the CALCIUM 360° trial and current cost data. Incrementa...

journal_title：Journal of comparative effectiveness research

authors： Shammas NW,Boyes CW,Palli SR,Rizzo JA,Martinsen BJ,Kotlarz H,Mustapha JA

更新日期：2018-04-01 00:00:00

abstract：:Patients with acute coronary syndromes and severe multivessel or left main coronary artery disease have better outcomes when prompt revascularization is performed in addition to optimal medical therapy (OMT). However, in patients with stable ischemic heart disease, randomized strategy trials have revealed equipoise be...

journal_title：Journal of comparative effectiveness research

authors： Torosoff MT,Sidhu MS,Desai KP,Fein SA,Boden WE

更新日期：2015-09-01 00:00:00

abstract：AIM:To identify ongoing practices and opportunities for improving national comparative effectiveness research (CER) translation through dissemination and implementation (D&I) via NIH-funded Clinical and Translational Science Award (CTSA) institutions. MATERIALS & METHODS:Key informant interviews were conducted with 18...

journal_title：Journal of comparative effectiveness research

authors： Morrato EH,Concannon TW,Meissner P,Shah ND,Turner BJ

更新日期：2013-03-01 00:00:00

abstract：AIM:To evaluate overall survival (OS) in unresectable American Joint Committee on Cancer (AJCC) stage I/II hepatocellular carcinoma (HCC) treated with drug-eluting-bead transarterial chemoembolization (DEB-TACE) versus best supportive care. MATERIALS & METHODS:OS in consecutive patients with AJCC stage I/II unresectab...

journal_title：Journal of comparative effectiveness research

authors： Xing M,Kokabi N,Prajapati HJ,Close O,Ludwig JM,Kim HS

更新日期：2016-03-01 00:00:00

abstract：:Aim: The systematic review assessed the effect of mindfulness-based interventions on the quality of life among women with breast cancer. Methods: PubMed, Cochrane library, EMBASE, Web of Science and CINAHL databases were searched for studies published. Our review assessed the effect of mindfulness-based interventions ...

journal_title：Journal of comparative effectiveness research

authors： Zhang X,Liu D,Li Y,Zhang Y,Zhang B,Wang X,Wang G

更新日期：2019-08-01 00:00:00

abstract：:Comparative effectiveness research (CER) calls for substantial changes in the way clinical research is conducted, interpreted and practically applied in the USA, in order to produce useful clinical evidence. Departing from classic efficacy and effectiveness research, the evolving CER paradigm requires structural and s...

journal_title：Journal of comparative effectiveness research

authors： Greenfield S,Kaplan SH

更新日期：2012-05-01 00:00:00

abstract：AIM:To estimate healthcare utilization and costs in amyloid light-chain (AL) amyloidosis. PATIENTS & METHODS:AL amyloidosis patients were identified in 2007-2015 claims databases if they had ≥1 inpatient/≥2 outpatient claims consistent with AL amyloidosis and received ≥1 AL-specific treatment. Descriptive statistics w...

journal_title：Journal of comparative effectiveness research

authors： Quock TP,Yan T,Chang E,Guthrie S,Broder MS

更新日期：2018-06-01 00:00:00

abstract：AIMS:This study aimed to identify methods to engage hard-to-reach patients in the research process. MATERIALS & METHODS:With funding from the Patient-Centered Outcomes Research Institute (Washington, DC, USA), the University of Maryland (MD, USA) conducted 20 focus groups and one individual interview. The sample consi...

journal_title：Journal of comparative effectiveness research

authors： Kauffman KS,Dosreis S,Ross M,Barnet B,Onukwugha E,Mullins CD

更新日期：2013-05-01 00:00:00

abstract：AIMS:To develop principles for planning and conducting comparative effectiveness research (CER). METHODS:Beginning with a modified existing list of health technology assessment principles, we developed a set of CER principles using literature review, engagement of multiple experts and broad stakeholder feedback. RESU...

journal_title：Journal of comparative effectiveness research

authors： Luce BR,Drummond MF,Dubois RW,Neumann PJ,Jönsson B,Siebert U,Schwartz JS

更新日期：2012-09-01 00:00:00

abstract：:Aim: To evaluate the patterns of cancer patients-assessed quality of outpatient care in the USA. Materials & methods: Medical Expenditure Panel Survey datasets for the years 2011, 2013, 2015 and 2017 were accessed and adult participants with a history of cancer diagnosis were reviewed. Participants' assessments of dif...

journal_title：Journal of comparative effectiveness research

authors： Abdel-Rahman O

更新日期：2020-09-01 00:00:00

abstract：:Functional tricuspid regurgitation (FTR) is an acquired valvular abnormality that is most frequently encountered during the evaluation and operative management of left-sided heart failure and left heart valve disease. Observational studies have demonstrated that uncorrected significant FTR during mitral valve surgery ...

journal_title：Journal of comparative effectiveness research

authors： Rogers JH,Bolling SF

更新日期：2015-11-01 00:00:00

abstract：:Rationale, aim & objective: The goal of this study was to examine the health and economic impacts related to increased utilization of the Duke Smoking Cessation Program resulting from the addition of two relatively new referral methods - Best Practice Advisory and Population Outreach. Materials & methods: In a compani...

journal_title：Journal of comparative effectiveness research

authors： Datta SK,Dennis PA,Davis JM

更新日期：2020-08-01 00:00:00

abstract：:Aim: Medicaid versus private primary insurance status may predict in-hospital mortality and morbidity after total knee arthroplasty (TKA). Materials & methods: Regression models were used to test our hypothesis in patients in the State Inpatient Database (SID) from five states who underwent primary TKA from January 20...

journal_title：Journal of comparative effectiveness research

authors： Maman SR,Andreae MH,Gaber-Baylis LK,Turnbull ZA,White RS

更新日期：2019-10-01 00:00:00

abstract：:Aim: To perform cost-effectiveness analysis (CEA) and budget impact analysis (BIA) comparing stenting to standard medical treatment (SMT) for the management of deep venous outflow obstruction and leg ulcers from the Italian Healthcare Service perspective. Materials & methods: A Markov model was developed to project co...

journal_title：Journal of comparative effectiveness research

authors： Rognoni C,Lugli M,Maleti O,Tarricone R

更新日期：2020-07-01 00:00:00

abstract：AIM:The importance of adjusting for cross-study heterogeneity when conducting network meta-analyses (NMAs) was demonstrated using a case study of biologic therapies for moderate-to-severe plaque psoriasis. METHODS:Bayesian NMAs were conducted for Psoriasis Area and Severity Index 90 response. Several covariates were c...

journal_title：Journal of comparative effectiveness research

authors： Cameron C,Hutton B,Druchok C,McElligott S,Nair S,Schubert A,Situ A,Varu A,Villacorta R

更新日期：2018-11-01 00:00:00

abstract：AIMS:To analyze administrative claims data from Medicaid, Medicare and commercial insurance sources to estimate stroke risk, bleeding risk, and the use of antithrombotic treatment in patients with atrial fibrillation (AF). METHODS:Included patients were aged ≥18 years with a new or existing diagnosis of AF. Outcomes w...

journal_title：Journal of comparative effectiveness research

authors： Lang K,Federico V,Patel AA,Munsell M,Nelson WW,Owens G,Mody SH,Schein J,Menzin J

更新日期：2016-01-01 00:00:00