Antithrombotic use and bleeding risk in patients with atrial fibrillation: findings from a multipayer analysis.

abstract：BACKGROUND:Palliative cancer patients often require clinic or hospital follow-up after any treatment intervention they may have received. This is typically done in person at either a hospital or a clinic. In these advanced cancer patients, this may be burdensome and result in attrition. Telephone follow-up is becoming ...

journal_title：Journal of comparative effectiveness research

authors： Zhou M,Holden L,Bedard G,Zeng L,Lam H,Chu D,Lao N,Lauzon N,Chow E

更新日期：2012-11-01 00:00:00

abstract：AIM:Reducing the fluctuation of blood pressure has recently been recognized as a potential target for improving management of hypertension to prevent cardiovascular events, particularly for strokes. Some randomized controlled trials demonstrated that amlodipine can effectively reduce blood pressure as a well-establishe...

journal_title：Journal of comparative effectiveness research

authors： Zhang L,Yang J,Li L,Liu D,Xie X,Dong P,Lin Y

更新日期：2018-07-01 00:00:00

abstract：:Aim: To compare secukinumab with infliximab in biologic-naive patients with psoriatic arthritis using matching-adjusted indirect comparison. Patients & methods: Individual patient baseline data for secukinumab were matched to published aggregate data for infliximab by key baseline characteristics, with matching weight...

journal_title：Journal of comparative effectiveness research

authors： Strand V,McInnes I,Mease P,Nash P,Thom H,Kalyvas C,Hunger M,Gandhi K,Pricop L,Jugl S,Choy E

更新日期：2019-05-01 00:00:00

abstract：:Since 2010, four oral anticoagulants have been approved for marketing in addition to warfarin for treatment of thromboembolic disease. Limited head-to-head data exist comparing these treatments, leaving patients and clinicians with little guidance for selecting a strategy that balances recurrence reduction with bleedi...

journal_title：Journal of comparative effectiveness research

authors： Krumme AA,Pawar A,Schneeweiss S,Glynn RJ,Choudhry NK,Kulldorff M,Ortiz AS,Avorn J,Gagne JJ

更新日期：2018-01-01 00:00:00

abstract：:Aim: To evaluate the patterns of cancer patients-assessed quality of outpatient care in the USA. Materials & methods: Medical Expenditure Panel Survey datasets for the years 2011, 2013, 2015 and 2017 were accessed and adult participants with a history of cancer diagnosis were reviewed. Participants' assessments of dif...

journal_title：Journal of comparative effectiveness research

authors： Abdel-Rahman O

更新日期：2020-09-01 00:00:00

abstract：AIM:To provide an overview of thresholds for incremental cost-effectiveness ratios (ICERs) representing willingness-to-pay (WTP) across multiple countries and insights into exemptions pertaining to the ICER (e.g., cancer). To compare ICER thresholds to individual country's estimated ability-to-pay. MATERIALS & METHODS...

journal_title：Journal of comparative effectiveness research

authors： Schwarzer R,Rochau U,Saverno K,Jahn B,Bornschein B,Muehlberger N,Flatscher-Thoeni M,Schnell-Inderst P,Sroczynski G,Lackner M,Schall I,Hebborn A,Pugner K,Fehervary A,Brixner D,Siebert U

更新日期：2015-09-01 00:00:00

abstract：:The COVID-19 pandemic is revealing the unacceptable health disparities across New York City and in this country. The mortality rates of vulnerable and minority populations alone suggest a need to re-evaluate clinical decision making protocols, especially given the recently passed Emergency or Disaster Treatment Protec...

journal_title：Journal of comparative effectiveness research

authors： Caraccio C,White RS,Jotwani R

更新日期：2020-08-01 00:00:00

abstract：AIM:To evaluate overall survival (OS) in unresectable American Joint Committee on Cancer (AJCC) stage I/II hepatocellular carcinoma (HCC) treated with drug-eluting-bead transarterial chemoembolization (DEB-TACE) versus best supportive care. MATERIALS & METHODS:OS in consecutive patients with AJCC stage I/II unresectab...

journal_title：Journal of comparative effectiveness research

authors： Xing M,Kokabi N,Prajapati HJ,Close O,Ludwig JM,Kim HS

更新日期：2016-03-01 00:00:00

abstract：AIM:Many hepatitis C virus regimens are unlikely to be compared head to head. In more difficult to treat populations where there is no standard of care, trials are single arm. We describe a flexible meta-analysis platform in this setting. METHODS:Our meta-analysis is literature based. We illustrate our methodology and...

journal_title：Journal of comparative effectiveness research

authors： Broglio KR,Daar ES,Quintana M,Yuan Y,Kalsekar A,Spellberg B,Lewis RJ,Akker Dv,Detry MA,Le T,Berry SM

更新日期：2015-03-01 00:00:00

abstract：:Alternative approaches to the current rebate system are being considered by policymakers and stakeholders in the private insurance market. This paper presents an analysis of three alternative options to the current rebate model: retaining retroactive rebates but requiring 100% pass-through of rebates and fees to plan ...

journal_title：Journal of comparative effectiveness research

authors： Pearson SD,Segel C,Cole A,Henshall C,Towse A

更新日期：2019-10-01 00:00:00

abstract：:Comparative effectiveness research (CER) calls for substantial changes in the way clinical research is conducted, interpreted and practically applied in the USA, in order to produce useful clinical evidence. Departing from classic efficacy and effectiveness research, the evolving CER paradigm requires structural and s...

journal_title：Journal of comparative effectiveness research

authors： Greenfield S,Kaplan SH

更新日期：2012-05-01 00:00:00

abstract：AIM:To identify ongoing practices and opportunities for improving national comparative effectiveness research (CER) translation through dissemination and implementation (D&I) via NIH-funded Clinical and Translational Science Award (CTSA) institutions. MATERIALS & METHODS:Key informant interviews were conducted with 18...

journal_title：Journal of comparative effectiveness research

authors： Morrato EH,Concannon TW,Meissner P,Shah ND,Turner BJ

更新日期：2013-03-01 00:00:00

abstract：:Translation of medical evidence into practice has not kept pace with the growth of medical technology and knowledge. We present three case studies--statins, drug eluting stents and bone marrow transplantation for breast cancer--to propose a framework for describing five factors that may influence the rate of adoption....

journal_title：Journal of comparative effectiveness research

authors： Dubois RW,Lauer M,Perfetto E

更新日期：2013-07-01 00:00:00

abstract：:Aim: We assessed reporting of data on sex/gender and race/ethnicity in randomized controlled trials of interventions published in the highest-ranking anesthesiology journals from 2014 to 2017. Methods: We extracted data regarding terminology for sex/gender, proportion of participants according to the race/gender and r...

journal_title：Journal of comparative effectiveness research

authors： Begic D,Janda-Martinac C,Vrdoljak M,Puljak L

更新日期：2019-12-01 00:00:00

abstract：AIM:The importance of adjusting for cross-study heterogeneity when conducting network meta-analyses (NMAs) was demonstrated using a case study of biologic therapies for moderate-to-severe plaque psoriasis. METHODS:Bayesian NMAs were conducted for Psoriasis Area and Severity Index 90 response. Several covariates were c...

journal_title：Journal of comparative effectiveness research

authors： Cameron C,Hutton B,Druchok C,McElligott S,Nair S,Schubert A,Situ A,Varu A,Villacorta R

更新日期：2018-11-01 00:00:00

abstract：:Functional tricuspid regurgitation (FTR) is an acquired valvular abnormality that is most frequently encountered during the evaluation and operative management of left-sided heart failure and left heart valve disease. Observational studies have demonstrated that uncorrected significant FTR during mitral valve surgery ...

journal_title：Journal of comparative effectiveness research

authors： Rogers JH,Bolling SF

更新日期：2015-11-01 00:00:00

abstract：:The intense competition that accompanied the growth of internet-based companies ushered in the era of 'big data' characterized by major innovations in processing of very large amounts of data and the application of advanced analytics including data mining and machine learning. Healthcare is on the cusp of its own era ...

journal_title：Journal of comparative effectiveness research

authors： Berger ML,Doban V

更新日期：2014-03-01 00:00:00

abstract：:AIMS: Stakeholder engagement is fundamental to comparative effectiveness research (CER), but lacks consistent terminology. This paper aims to define stakeholder engagement and present a conceptual model for involving stakeholders in CER. MATERIALS #ENTITYSTARTX00026; METHODS: The definitions and model were developed f...

journal_title：Journal of comparative effectiveness research

authors： Deverka PA,Lavallee DC,Desai PJ,Esmail LC,Ramsey SD,Veenstra DL,Tunis SR

更新日期：2012-03-01 00:00:00

abstract：AIM:Develop an accessible exercise to engage underserved populations about research funding priorities; analyze the criteria they use to prioritize research; contrast these criteria to those currently used by Patient Centered Outcomes Research Institute (PCORI). MATERIALS & METHODS:Academic and community partners coll...

journal_title：Journal of comparative effectiveness research

authors： Cargill SS,Baker LL,Goold SD

更新日期：2017-07-01 00:00:00

abstract：:Aim: To perform cost-effectiveness analysis (CEA) and budget impact analysis (BIA) comparing stenting to standard medical treatment (SMT) for the management of deep venous outflow obstruction and leg ulcers from the Italian Healthcare Service perspective. Materials & methods: A Markov model was developed to project co...

journal_title：Journal of comparative effectiveness research

authors： Rognoni C,Lugli M,Maleti O,Tarricone R

更新日期：2020-07-01 00:00:00

abstract：:Clinical trial designs often fail to deliver data that jointly satisfy evolving demands of both regulatory and reimbursement authorities. We propose a new multi-tiered trial design to integrate efficacy and effectiveness, and address the evolving needs of authorities. The mixed randomized trial allocates patients firs...

journal_title：Journal of comparative effectiveness research

authors： Alsop J,Scott M,Archey W

更新日期：2016-11-01 00:00:00

abstract：AIM:Explore perspectives of adolescent and young adult (AYA) and parent stakeholders regarding their engagement in comparative effectiveness research (CER) evaluating cholesterol screening and treatment strategies for 17-21 year olds. METHODS:All nine AYAs and parent stakeholders participating in a 20-member panel of ...

journal_title：Journal of comparative effectiveness research

authors： Saunders T,Mackie TI,Shah S,Gooding H,de Ferranti SD,Leslie LK

更新日期：2016-08-01 00:00:00

abstract：:Evaluation of: Olanow CW, Kieburtz K, Odin P et al. Continuous intrajejunal infusion of levodopa-carbidopa intestinal gel for patients with advanced Parkinson's disease: a randomised, controlled, double-blind, double-dummy study. Lancet Neurol. 13(2), 141-149 (2014). Levodopa-induced motor complications, including mot...

journal_title：Journal of comparative effectiveness research

authors： Guthikonda LN,Lyons KE,Pahwa R

更新日期：2014-07-01 00:00:00

abstract：:As the Senior Editors of the Journal of Comparative Effectiveness Research (JCER) we are delighted to present you with the first issue of this exciting new publication, focusing on the socially and clinically impactful field of comparative effectiveness research (CER). ...

journal_title：Journal of comparative effectiveness research

authors： Greenfield S,Rich E

更新日期：2012-01-01 00:00:00

abstract：AIMS:This study aimed to identify methods to engage hard-to-reach patients in the research process. MATERIALS & METHODS:With funding from the Patient-Centered Outcomes Research Institute (Washington, DC, USA), the University of Maryland (MD, USA) conducted 20 focus groups and one individual interview. The sample consi...

journal_title：Journal of comparative effectiveness research

authors： Kauffman KS,Dosreis S,Ross M,Barnet B,Onukwugha E,Mullins CD

更新日期：2013-05-01 00:00:00

abstract：AIM:We conducted a meta-analysis to compare the efficacy and safety of oral and intravenous applications of tranexamic acid (TXA) in total hip arthroplasty (THA). MATERIALS & METHODS:Electronic databases, including PubMed, Cochrane CENTRAL, ScienceDirect and Embase, were searched to identify the studies comparing the ...

journal_title：Journal of comparative effectiveness research

authors： Wang L,Cao JG,Liu J

更新日期：2019-04-01 00:00:00

abstract：AIM:Details of data quality and how quality issues were solved have not been reported in published comparative effectiveness studies using electronic health record data. METHODS:We developed a conceptual framework of data quality assessment and preprocessing and apply it to a study comparing angiotensin-converting enz...

journal_title：Journal of comparative effectiveness research

authors： Huang Y,Voorham J,Haaijer-Ruskamp FM

更新日期：2016-07-01 00:00:00

abstract：:Aim: To compare efficacy between total gastrectomy (TG) and proximal gastrectomy (PG) for upper-third gastric cancer. Materials & methods: PubMed, Embase and Cochrane library were searched to select suitable researches. Stata was used for meta-analysis including 5-year overall survival rate, recurrence rate, complicat...

journal_title：Journal of comparative effectiveness research

authors： Chen YC,Lu L,Fan KH,Wang DH,Fu WH

更新日期：2019-07-01 00:00:00

abstract：AIM:The incremental cost of peripheral orbital atherectomy system (OAS) plus balloon angioplasty (BA) versus BA-only for critical limb ischemia was estimated. MATERIALS & METHODS:A deterministic simulation model used clinical and healthcare utilization data from the CALCIUM 360° trial and current cost data. Incrementa...

journal_title：Journal of comparative effectiveness research

authors： Shammas NW,Boyes CW,Palli SR,Rizzo JA,Martinsen BJ,Kotlarz H,Mustapha JA

更新日期：2018-04-01 00:00:00

abstract：:Aim: Medicaid versus private primary insurance status may predict in-hospital mortality and morbidity after total knee arthroplasty (TKA). Materials & methods: Regression models were used to test our hypothesis in patients in the State Inpatient Database (SID) from five states who underwent primary TKA from January 20...

journal_title：Journal of comparative effectiveness research

authors： Maman SR,Andreae MH,Gaber-Baylis LK,Turnbull ZA,White RS

更新日期：2019-10-01 00:00:00